Receptor de adenosina
Los receptores de adenosina son una clase de GPCR que responden al nucleósido endógeno adenosina. Estos receptores están involucrados en la regulación de diversos procesos fisiológicos, incluidos la función cardiovascular, los ciclos sueño-vigilia y las respuestas inmunitarias. Los moduladores de los receptores de adenosina tienen un potencial terapéutico en el tratamiento de afecciones como las arritmias cardíacas, la inflamación y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una selección de moduladores de receptores de adenosina de alta calidad para apoyar su investigación en biología cardiovascular, neurociencia e inmunología.
Se han encontrado 242 productos de "Receptor de adenosina"
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PSB-10 hydrochloride
CAS:<p>PSB-10 hydrochloride is a human adenosine A3 receptor antagonist.</p>Fórmula:C16H15Cl4N5OPureza:98%Forma y color:SolidPeso molecular:435.14MSX-2
CAS:<p>MSX-2 is an A2A adenosine receptor antagonist.</p>Fórmula:C21H22N4O4Pureza:98%Forma y color:SolidPeso molecular:394.42MNI-444
CAS:<p>MNI-444 is a PET radiotracer for adenosine 2A receptors.</p>Fórmula:C24H26FN9O2Forma y color:SolidPeso molecular:491.52KF21213
CAS:<p>KF21213 shows a high affinity for the adenosine A2A receptors (Ki=3.0 nM). KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors.</p>Fórmula:C19H22N4O3Pureza:98%Forma y color:SolidPeso molecular:354.4ATL802
CAS:<p>ATL802 is an adenosine A2B Receptor antagonist.</p>Fórmula:C24H22F3N7O3Pureza:98%Forma y color:SolidPeso molecular:513.47MRS5698
CAS:<p>MRS5698, an A3 adenosine receptor agonist with Ki ~3 nM, blocks chronic pain, highly selective (>1000-fold over A1/A2A).</p>Fórmula:C28H23ClF2N6O3Pureza:98%Forma y color:SolidPeso molecular:564.97ST4206
CAS:<p>ST4206 is an antagonist of adenosine A2A. For adenosine A2A receptor and adenosine A1 receptor, the Kis values are 12 nM and 197 nM , respectively.</p>Fórmula:C12H14N8OPureza:98%Forma y color:SolidPeso molecular:286.29A1/A3 AR antagonist 3
CAS:<p>A1/A3 AR Antagonist 3 is a dual A1R/A3R antagonist that demonstrates high affinity within the low-micromolar to nanomolar range, and is potentially useful in</p>Fórmula:C22H19N5O3Pureza:98%Forma y color:SolidPeso molecular:401.42PF-02575799
CAS:<p>PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).</p>Fórmula:C42H37FN4O4Pureza:98%Forma y color:SolidPeso molecular:680.77PSB 0788
CAS:<p>adenosine A2B receptor antagonist</p>Fórmula:C25H27ClN6O4SPureza:98%Forma y color:SolidPeso molecular:543.04CGS 21680
CAS:<p>CGS 21680 is a chemical compound that acts as a selective agonist for both adenosine and its A2A receptor, demonstrating a binding affinity (K i) of 27 nM.</p>Fórmula:C23H29N7O6Forma y color:SolidPeso molecular:499.52Dansyl-NECA
CAS:<p>Dansyl-NECA is a selective agonist of fluorescent adenosine A1 receptor.</p>Fórmula:C30H40N8O6SForma y color:SolidPeso molecular:640.75PSB-1901 free base
CAS:<p>PSB-1901: potent A2B Adenosine Receptor Antagonist; Ki=0.0835 nM; >10,000x selective; effective in mice for preclinical studies.</p>Fórmula:C24H25BrN6O4SForma y color:SolidPeso molecular:573.46CV1808
CAS:<p>CV-1808 is a coronary vasodilator, antihypertensive, and antipsychotic following systemic administration in vivo. CV-1808 is an adenosine A2 receptor agonist.</p>Fórmula:C16H18N6O4Forma y color:Off-White To Pale Yellow SolidPeso molecular:358.35GS-6201
CAS:<p>GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor.</p>Fórmula:C21H21F3N6O2Pureza:99.74% - 99.78%Forma y color:SolidPeso molecular:446.43MRS 1754
CAS:<p>MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.</p>Fórmula:C26H26N6O4Pureza:97.57% - 99.3%Forma y color:SolidPeso molecular:486.52A2B receptor antagonist 1
CAS:<p>A2B receptor antagonist 1 (EXAMPLE 9B) is a potent A2B adenosine receptor antagonist.</p>Fórmula:C21H24N6O2Pureza:99.53%Forma y color:SolidPeso molecular:392.45PSB-603
CAS:<p>PSB-603 is a selective antagonist of Adenosine A2B receptor(Ki = 0.553 nM) with anti-inflammatory effects.</p>Fórmula:C24H25ClN6O4SPureza:97.13%Forma y color:SolidPeso molecular:529.01PSB 1115
CAS:<p>PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.</p>Fórmula:C14H14N4O5SPureza:98.69% - >99.99%Forma y color:SolidPeso molecular:350.35A1/A3 AR antagonist 1
<p>Compound 10 is a potent dual A1/A3 AR antagonist, with Ki values of 37.6 nM (hA1), 25.4 nM (hA3), and 1.47 nM (rA1), studied in renal, lung, and Alzheimer's.</p>Fórmula:C24H18N2O3SForma y color:SolidPeso molecular:414.48L-97-1
CAS:<p>L-97-1 is an antagonist of the adenosine A1 receptor.</p>Fórmula:C29H38N6O3Pureza:98%Forma y color:SolidPeso molecular:518.65CVT-5440
CAS:<p>CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.</p>Fórmula:C27H28N6O5Forma y color:SolidPeso molecular:516.55A1AR antagonist 1
<p>Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).</p>Fórmula:C18H14N4OForma y color:SolidPeso molecular:302.33DMPX
CAS:<p>DMPX (3,7-Dimethyl-1-propargylxanthine) is a caffeine-like compound capable of crossing the blood-brain barrier. It serves as an A2-selective adenosine receptor (AR) antagonist, effectively and selectively blocking the hypothermia and behavioral inhibition induced by A2 adenosine receptor agonists, such as NECA. DMPX is utilized in research on diseases like Parkinson's disease.</p>Fórmula:C10H10N4O2Forma y color:SolidPeso molecular:218.212A2A receptor antagonist 2
<p>A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).</p>Fórmula:C25H28FN7O3Forma y color:SolidPeso molecular:493.53ADORA2A/PDE4D-IN-1
CAS:<p>ADORA2A/PDE4D-IN-1 (Compound 9) is a dual inhibitor of the adenosine A2a receptor (ADORA2A) and phosphodiesterase 4D (PDE4D). This compound is applicable for research in bronchial asthma.</p>Fórmula:C14H11N5Forma y color:SolidPeso molecular:249.271PSB 36
CAS:<p>A1 adenosine receptor antagonist</p>Fórmula:C21H30N4O3Pureza:98%Forma y color:SolidPeso molecular:386.49LJ-4517
<p>LJ-4517 is an effective A2AAR antagonist (Ki=18.3 nM). LJ-4517 can effectively replace the binding of [3H] ZM241385 at WT A2AAR.</p>Fórmula:C19H21N5O3SForma y color:SolidPeso molecular:399.47M1069
<p>M1069 is an oral A2A/A2B receptor antagonist, 100x more selective over A1/A3, with antitumor properties by blocking adenosine's immunosuppressive effects.</p>Fórmula:C25H30N4O8SForma y color:SolidPeso molecular:546.59UK-432097
CAS:<p>UK 432097 is an adenosine A2A agonist.</p>Fórmula:C40H47N11O6Forma y color:SolidPeso molecular:777.87YGZ-331
CAS:<p>YGZ-331, a sedative hypnotic, acts by elevating GABA levels as a derivative of the adenosine nucleoside NGBA. It functions through activating A1R and A2aR, and inhibiting the phosphorylation of CaMKII (pCaMKII), thereby exerting its calming effects. Additionally, YGZ-331 reduces spontaneous motor activity in mice.</p>Fórmula:C19H23N5O4Forma y color:SolidPeso molecular:385.42CP-608039
CAS:<p>CP-608039 is a selective adenosine A3 receptor agonist for both human A3 and human A1 receptors.</p>Fórmula:C23H25ClN8O5Forma y color:SolidPeso molecular:528.95Neladenoson
CAS:<p>Neladenoson is an effective and selective agonist of the Adenosine A1 Receptor (A1R). EGFR-IN-162 shows potential for research in heart failure.</p>Fórmula:C29H24ClN5O2S2Forma y color:SolidPeso molecular:574.12MRS7799
CAS:<p>MRS7799 is a selective A3 Adenosine Receptor antagonist with Kd values of 0.55 nM for humans, 3.74 nM for mice, and 2.80 nM for rats. MRS7799 can be utilized in research related to neurodegenerative diseases, cancer, cardiac and cerebral ischemia, and autoimmune inflammatory diseases.</p>Fórmula:C22H18N4OSForma y color:SolidPeso molecular:386.47Tonapofylline
CAS:<p>Tonapofylline, orally active, selectively blocks A1 adenosine receptor (Ki: 7.4 nM), used in heart failure research.</p>Fórmula:C22H32N4O4Pureza:98.57%Forma y color:SolidPeso molecular:416.51A3AR antagonist 5
CAS:<p>A3AR antagonist 5 (Compound 16) acts as a selective antagonist for the human adenosine A3 receptor (human adenosine A3 receptor), with an affinity expressed as a pC value of 4.542 μM.</p>Fórmula:C18H16N2O2SForma y color:SolidPeso molecular:324.40hA3AR agonist 1
<p>hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .</p>Fórmula:C10H14N6OSForma y color:SolidPeso molecular:266.32KF26777
CAS:<p>KF26777 is a potent and selective antagonist of adenosine A3 receptor.</p>Fórmula:C16H16BrN5OPureza:98%Forma y color:SolidPeso molecular:374.23MSX-3
CAS:<p>MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.</p>Fórmula:C21H23N4Na2O7PPureza:98%Forma y color:SolidPeso molecular:520.389Inupadenant HCl
CAS:<p>Inupadenant (EOS-850) is a selective A2a receptor antagonist, targeting immunosuppression in tumors.</p>Fórmula:C25H27ClF2N8O4S2Forma y color:SolidPeso molecular:641.11ATL444
CAS:<p>ATL444 is an adenosine receptor antagonist with affinity (Ki values) for rA1AR, rA2AAR, rA2BAR, and rA3AR of 7.0, 2.5, 61.8, and >1000 nM, respectively.</p>Fórmula:C17H19N5OForma y color:SolidPeso molecular:309.37Zaladenant
CAS:<p>Zaladenant is an adenosine receptor antagonist with antitumor properties.</p>Fórmula:C19H15F3N6OForma y color:SolidPeso molecular:400.357
