Receptor de adenosina
Los receptores de adenosina son una clase de GPCR que responden al nucleósido endógeno adenosina. Estos receptores están involucrados en la regulación de diversos procesos fisiológicos, incluidos la función cardiovascular, los ciclos sueño-vigilia y las respuestas inmunitarias. Los moduladores de los receptores de adenosina tienen un potencial terapéutico en el tratamiento de afecciones como las arritmias cardíacas, la inflamación y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una selección de moduladores de receptores de adenosina de alta calidad para apoyar su investigación en biología cardiovascular, neurociencia e inmunología.
Se han encontrado 215 productos para "Receptor de adenosina".
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hA3AR agonist 2
hA3AR agonist 2 is a potent activator of A3AR, with a Ki value of 3.5 nM.Fórmula:C11H14ClN5O2SForma y color:SolidPeso molecular:315.78LUF6096
CAS:LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically whileFórmula:C22H21Cl2N3OPureza:99.5%Forma y color:White SolidPeso molecular:414.33A3AR agonist 2
Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM.Fórmula:C34H34N6O6Pureza:98%Forma y color:SolidPeso molecular:622.67Xanthine amine congener dihydrochloride
CAS:XAC dihydrochloride is an Adenosine A1 and A2 receptor antagonist with IC50s of 1.8 nM and 114 nM, also a mouse convulsant.Fórmula:C21H30Cl2N6O4Forma y color:SolidPeso molecular:501.41PSB 0777 ammonium hydrate
PSB 0777 ammonium hydrate is a potent and selective adenosine A2A receptor full agonist, exhibiting K i values of 44.4 nM for rat A2A receptors and 360 nM forFórmula:C18H20N5O7S2·NH4·75H2OPureza:98%Forma y color:SolidPeso molecular:532.09Heterobivalent ligand-1
Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.Fórmula:C86H115FN16O21Forma y color:SolidPeso molecular:1727.93Adenosine receptor agonist 1
Compound 6m, an A3 adenosine receptor (AR) partial agonist, exhibits a K i value of 6.7 nM as an adenosine receptor agonist.Fórmula:C12H14ClN5O2SeForma y color:SolidPeso molecular:374.68A3AR modulator 1
MRS8054 is an oral A3 adenosine receptor positive allosteric modulator, enhancing Cl-IB-MECA-induced activity.Fórmula:C23H25IN4Forma y color:SolidPeso molecular:484.38Inupadenant
CAS:Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity[1].Fórmula:C25H26F2N8O4S2Forma y color:SolidPeso molecular:604.65A-286501
CAS:A-286501: Oral adenosine kinase inhibitor, IC50=0.47 nM, reduces pain via non-opioid, non-NSAID ADO receptors.Fórmula:C11H14BrN5O2Pureza:98%Forma y color:SolidPeso molecular:328.17LUF7690
CAS:LUF7690 (Compound 9), a clickable and covalent affinity-based probe (AfBP) for the human A3 adenosine receptor (hA3AR), facilitates the detection andFórmula:C25H24FN5O6SForma y color:SolidPeso molecular:541.553F6-9G5
3F6-9G5 is a humanized monoclonal antibody targeting AA2AR/Adenosine A2aR, used in neurodegenerative disease research.Pureza:>95%Forma y color:LiquidPeso molecular:146.66 kDaA2A/A3 AR antagonist-1
A2A/A3 AR antagonist-1 is a dual fluorescent AR ligand with K i of 90 nM (hA2A) & 31.8 nM (hA3).Fórmula:C56H71N15O12S2Forma y color:SolidPeso molecular:1210.39AR ligand 40
AR ligand 40 (compound 19c) is an Adenosine A1 Receptor ligand with antagonistic activity. It exhibits antiproliferative effects on SW480, SW48, HCT116, K562, MDA-MB-231, and A549 cells, with EC50 values of 7, 10, 12, 13, 15, and 39 μM, respectively.Fórmula:C21H25N5Forma y color:SolidPeso molecular:347.211ABT-702
CAS:ABT-702 is an orally active, competitive, and reversible non-nucleoside adenosine kinase (AK) inhibitor analgesic and anti-inflammatory.Fórmula:C22H19BrN6OPureza:99.57%Forma y color:SoildPeso molecular:463.33Theophyllol
CAS:Theophyllol (theophylline sodium acetate) can alter calcium levels in subcellular fractions of rat brain cortex.Fórmula:C9H10N4Na2O4Forma y color:SolidPeso molecular:284.18Adenosine receptor antagonist 1
CAS:A2aR-selective antagonist with IC50 of 0.29 nM; 14x more selective over A2bR.Fórmula:C22H15ClFN7OForma y color:SolidPeso molecular:447.86MRS-1706
CAS:MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.Fórmula:C27H29N5O5Pureza:99.00%Forma y color:SolidPeso molecular:503.55Ref: TM-T16136
1mg34,00€5mg74,00€1mL*10mM (DMSO)84,00€10mg113,00€25mg222,00€50mg356,00€100mg572,00€200mg803,00€A3AR agonist 1
A3AR Agonist 1 (Compound 12), with a Ki of 25.8 nM, is a potent A3 adenosine receptor (A3AR) agonist that promotes β-arrestin2 recruitment with an effectiveFórmula:C28H34N6O6Pureza:98%Forma y color:SolidPeso molecular:550.61A3AR antagonist 6
A3AR antagonist 6 (Compound 5p) is a selective A3AR antagonist with a Ki of 6.8 nM, suitable for tumor research.
