DHFR
La dihidrofolato reductasa (DHFR) es una enzima que desempeña un papel crucial en el ciclo del folato, esencial para la síntesis, reparación y metilación del ADN. Los inhibidores de DHFR se utilizan ampliamente como agentes quimioterapéuticos en el tratamiento del cáncer y las enfermedades autoinmunes debido a su capacidad para inhibir la proliferación celular. En CymitQuimica, ofrecemos una variedad de inhibidores de DHFR para apoyar su investigación en terapia contra el cáncer, inmunología y biología molecular.
Se han encontrado 32 productos de "DHFR"
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Dihydrofolate reductase Protein, Human, Recombinant (His)
Key enzyme in folate metabolism.Forma y color:Lyophilized PowderPeso molecular:25.5 kDa (predicted)Ref: TM-TMPH-01224
1mg1.738,00€5µg82,00€10µg117,00€20µg188,00€50µg283,00€100µg405,00€200µg625,00€500µg1.111,00€Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
Key enzyme in folate metabolism.Forma y color:Lyophilized PowderPeso molecular:22.0 kDa (predicted)Ref: TM-TMPH-03581
1mg2.480,00€5µg137,00€10µg223,00€20µg371,00€50µg549,00€100µg754,00€200µg1.083,00€500µg1.696,00€DHFR-IN-5
CAS:DHFR-IN-5: potent, oral DHFR inhibitor, Ki 0.54 nM against mutant P. falciparum, anti-malarial.
Fórmula:C18H24N4O4Forma y color:SolidPeso molecular:360.41(Rac)-Managlinat dialanetil
CAS:Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.
Fórmula:C21H33N4O6PSPureza:98.52%Forma y color:SolidPeso molecular:500.5510-Deazaaminopterin
CAS:10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.Fórmula:C20H21N7O5Forma y color:SolidPeso molecular:439.42Clociguanil
CAS:Clociguanil has antimalarial activity.Fórmula:C12H15Cl2N5OForma y color:SolidPeso molecular:316.19Piritrexim
CAS:Piritrexim (BW 301U) is an orally available fat-soluble dihydrofolate reductase inhibitor with pulmonary toxicity used in the study of uroepithelial carcinomaFórmula:C17H19N5O2Pureza:98.50% - >99.99%Forma y color:SolidPeso molecular:325.37Talotrexin ammonium
CAS:Talotrexin ammonium, a non-polyglutamic antifolate, inhibits cancer by targeting DHFR.
Fórmula:C27H30N10O6Pureza:97.49%Forma y color:SolidPeso molecular:590.59Ref: TM-T64295
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€Phototrexate
CAS:Phototrexate, a photochromic Methotrexate analog, is a UVA-activated, reversible DHFR inhibitor with antifolate properties (IC50: 6 nM cis vs. 34 μM trans).Fórmula:C20H19N7O5Forma y color:SolidPeso molecular:437.41Brodimoprim
CAS:Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).Fórmula:C13H15BrN4O2Pureza:98% - 99.71%Forma y color:SolidPeso molecular:339.19Methotrexate-γ-aspartate
CAS:Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.Fórmula:C24H27N9O8Pureza:98%Forma y color:SolidPeso molecular:569.53DHFR-IN-4
CAS:DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.Fórmula:C18H21N5O2SPureza:99.41%Forma y color:SolidPeso molecular:371.46
