DHFR
La dihidrofolato reductasa (DHFR) es una enzima que desempeña un papel crucial en el ciclo del folato, esencial para la síntesis, reparación y metilación del ADN. Los inhibidores de DHFR se utilizan ampliamente como agentes quimioterapéuticos en el tratamiento del cáncer y las enfermedades autoinmunes debido a su capacidad para inhibir la proliferación celular. En CymitQuimica, ofrecemos una variedad de inhibidores de DHFR para apoyar su investigación en terapia contra el cáncer, inmunología y biología molecular.
Se han encontrado 34 productos para "DHFR".
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Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
Key enzyme in folate metabolism.Forma y color:Lyophilized PowderPeso molecular:22.0 kDa (predicted)Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
Key enzyme in folate metabolism.Forma y color:Lyophilized PowderPeso molecular:25.6 kDa (predicted)Dihydrofolate reductase Protein, Human, Recombinant (His)
Key enzyme in folate metabolism.Forma y color:Lyophilized PowderPeso molecular:25.5 kDa (predicted)QDPR-IN-1
CAS:QDPR-IN-1 (Compound 9b) is an effective inhibitor of QDPR, exhibiting an IC50 value of 0.72 μM.Fórmula:C12H15N3O2Forma y color:SolidPeso molecular:233.2664Piritrexim
CAS:Piritrexim (BW 301U) is an orally available fat-soluble dihydrofolate reductase inhibitor with pulmonary toxicity used in the study of uroepithelial carcinomaFórmula:C17H19N5O2Pureza:99.29% - >99.99%Forma y color:SolidPeso molecular:325.3651(Rac)-Managlinat dialanetil
CAS:Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.Fórmula:C21H33N4O6PSPureza:98.52%Forma y color:SolidPeso molecular:500.55Aditoprime
CAS:Aditoprime (Aditoprim) is a selective bacterial DHFR inhibitor with strong nanomolar potency and broad-spectrum antibacterial activity.Fórmula:C15H21N5O2Pureza:99.89%Forma y color:White SolidPeso molecular:303.36Clociguanil
CAS:Clociguanil has antimalarial activity.Fórmula:C12H15Cl2N5OForma y color:SolidPeso molecular:316.1910-Deazaaminopterin
CAS:10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.Fórmula:C20H21N7O5Forma y color:SolidPeso molecular:439.42DHFR-IN-5
CAS:DHFR-IN-5: potent, oral DHFR inhibitor, Ki 0.54 nM against mutant P. falciparum, anti-malarial.Fórmula:C18H24N4O4Forma y color:SolidPeso molecular:360.41Phototrexate
CAS:Phototrexate, a photochromic Methotrexate analog, is a UVA-activated, reversible DHFR inhibitor with antifolate properties (IC50: 6 nM cis vs. 34 μM trans).Fórmula:C20H19N7O5Forma y color:SolidPeso molecular:437.41TH9028
CAS:TH9028 inhibits MTHFD1/2/2L, induces replication stress & apoptosis, and shows anti-AML activity.Fórmula:C16H18N12O5Pureza:97.57%Peso molecular:458.39Methotrexate-γ-aspartate
CAS:Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.Fórmula:C24H27N9O8Pureza:98%Forma y color:SolidPeso molecular:569.53DHFR-IN-4
CAS:DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.Fórmula:C18H21N5O2SPureza:99.41%Forma y color:White SolidPeso molecular:371.46
