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Síntesis de ADN / ARN

Síntesis de ADN / ARN

Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.

Se han encontrado 708 productos de "Síntesis de ADN / ARN"

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  • UCK2 Inhibitor-3

    CAS:
    <p>UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.</p>
    Fórmula:C19H13BrFN5O2S
    Forma y color:Solid
    Peso molecular:474.31
  • Bromochloroacetonitrile

    CAS:
    <p>Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.</p>
    Fórmula:C2HBrClN
    Forma y color:Solid
    Peso molecular:154.39
  • Ac-rC Phosphoramidite

    CAS:
    <p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>
    Fórmula:C47H64N5O9PSi
    Pureza:98.29%
    Forma y color:Solid
    Peso molecular:902.1
  • MRK-952


    <p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>
    Fórmula:C20H20ClF3N6
    Forma y color:Solid
    Peso molecular:436.861
  • 5'-O-DMT-2'-O-TBDMS-Ac-rC

    CAS:
    <p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Fórmula:C38H47N3O8Si
    Forma y color:Solid
    Peso molecular:701.892
  • Uridine triphosphate 13C9,15N2 sodium

    CAS:
    <p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>
    Fórmula:C9H1415N2NaO15P3
    Forma y color:Solid
    Peso molecular:517.04
  • Guanosine triphosphate

    CAS:
    <p>Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].</p>
    Fórmula:C10H16N5O14P3
    Forma y color:Solid
    Peso molecular:523.18
  • Remdesivir nucleoside monophosphate

    CAS:
    <p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>
    Fórmula:C12H14N5O7P
    Forma y color:Solid
    Peso molecular:371.24
  • 5-BrdUTP sodium salt

    CAS:
    <p>5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.</p>
    Fórmula:C9H10BrN2Na4O14P3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:634.97
  • RNA splicing modulator 3

    CAS:
    <p>RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].</p>
    Fórmula:C19H20N6OS
    Forma y color:Solid
    Peso molecular:380.47
  • 8-NH2-ATP

    CAS:
    <p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>
    Fórmula:C10H17N6O13P3
    Forma y color:Solid
    Peso molecular:522.20
  • 3'-Deoxyuridine-5'-triphosphate trisodium


    <p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>
    Fórmula:C9H12N2Na3O14P3
    Forma y color:Soild
    Peso molecular:534.08
  • HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt

    CAS:
    <p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>
    Fórmula:C57H62N8O10S
    Forma y color:Solid
    Peso molecular:1051.21
  • 2'-OMe-Ac-C Phosphoramidite

    CAS:
    <p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>
    Fórmula:C42H52N5O9P
    Forma y color:Solid
    Peso molecular:801.86
  • CW-2


    <p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>
    Fórmula:C43H42Cl2FN11O10Pt
    Forma y color:Solid
    Peso molecular:1156.21251
  • Demycarosyl-3D-β-D-digitoxosylmithramycin SK

    CAS:
    <p>Demycarosyl-3D-β-D-digitoxosylmithramycin SK, an analog of Mithramycin, exhibits potent anti-tumor activity.</p>
    Fórmula:C50H72O23
    Forma y color:Solid
    Peso molecular:1041.09
  • Bz-rC Phosphoramidite

    CAS:
    <p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Fórmula:C52H66N5O9PSi
    Forma y color:Solid
    Peso molecular:964.185
  • LIN28-IN-2


    <p>LIN28-IN-2 (Compound Ln268) blocks the interaction between the zinc finger domain (ZKD) of Lin28 and RNA substrates, inhibiting both Lin28a and Lin28b. It also suppresses the proliferation of Lin28-positive cancer cells and the growth of 3D spheroids.</p>
    Fórmula:C9H7FN2O2S
    Forma y color:Solid
    Peso molecular:226.227
  • Carbazole

    CAS:
    <p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>
    Fórmula:C12H9N
    Pureza:99.82%
    Forma y color:Solid
    Peso molecular:167.211
  • Guanosine 5'-triphosphate trisodium salt hydrate

    CAS:
    <p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>
    Fórmula:C10H18N5NaO15P3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:564.185
  • KWR137


    <p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>
    Fórmula:C33H31ClF3N9O4
    Forma y color:Solid
    Peso molecular:710.105
  • EFdA-TP tetraammonium


    <p>EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.</p>
    Fórmula:C12H27N9O12P3
    Forma y color:Solid
    Peso molecular:601.31
  • Ribonuclease T1

    CAS:
    <p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>
    Forma y color:Solid
  • TS-002902


    <p>TS-002902 is a small molecule inhibitor of TUT4/7, exhibiting antiproliferative activity. It holds potential for use in cancer research.</p>
    Forma y color:Odour Solid
  • cis-Lomibuvir

    CAS:
    <p>cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.</p>
    Fórmula:C25H35NO4S
    Forma y color:Solid
    Peso molecular:445.61
  • RNA polymerase II-IN-2


    <p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>
    Fórmula:C41H58N10O12S
    Forma y color:Solid
    Peso molecular:915.02
  • 7-TFA-ap-7-Deaza-ddA

    CAS:
    <p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>
    Fórmula:C16H16F3N5O3
    Forma y color:Solid
    Peso molecular:383.331
  • AV-153

    CAS:
    <p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>
    Fórmula:C14H19NNaO6
    Forma y color:Solid
    Peso molecular:320.297
  • 5'-O-DMT-N4-Bz-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>
    Fórmula:C37H34FN3O7
    Forma y color:Solid
    Peso molecular:651.68
  • 3'Ome-m7GpppAmpG

    CAS:
    <p>3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.</p>
    Fórmula:C33H45N15O24P4
    Forma y color:Solid
    Peso molecular:1159.69
  • 7-Deazaxanthine

    CAS:
    <p>7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.</p>
    Fórmula:C6H5N3O2
    Forma y color:Solid
    Peso molecular:151.12
  • FR901463

    CAS:
    <p>FR 901463 is a biochemical.</p>
    Fórmula:C27H42ClNO8
    Forma y color:Solid
    Peso molecular:544.08
  • PINT-87aa TFA


    PINT-87aa TFA, an 87-aa peptide from LINC-PINT, binds PAF1c, blocking oncogene transcription and glioblastoma growth.
    Fórmula:C396H628N140O115S13·C2HF3O2
    Peso molecular:9721.05
  • DMT-5Me-dC(Bz)-CE Phosphoramidite

    CAS:
    <p>DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.</p>
    Fórmula:C47H54N5O8P
    Forma y color:Solid
    Peso molecular:847.93
  • 2'-Deoxy-2'-fluoro-l-uridine

    CAS:
    <p>2'-Deoxy-2'-fluoro-1-uridine: an L-nucleoside, inhibits RNA viruses by blocking viral RNA polymerase.</p>
    Fórmula:C9H11FN2O5
    Forma y color:Solid
    Peso molecular:246.19
  • Maleuric acid

    CAS:
    <p>Maleuric acid is an anti-mitotic agent for research and boosts growth and fertility in flora and fauna.</p>
    Fórmula:C5H6N2O4
    Pureza:98.92%
    Forma y color:Solid
    Peso molecular:158.11
  • c-Fos-IN-1


    <p>c-Fos-IN-1 (Compound P16) acts as a c-Jun inhibitor, effectively reducing the mRNA and protein levels of c-Fos. It also inhibits the phosphorylation activity of ERK and the transcriptional activity of AP-1. This compound demonstrates anticancer properties through the inhibition of the ERK/c-Fos/Jun pathway. c-Fos-IN-1 curbs the proliferation and migration of gastric cancer cells, with an IC50 of 2.31 μM for MGC-803 cells, causing cell cycle arrest at the G2/M phase and inducing apoptosis in cancer cells. Additionally, c-Fos-IN-1 hampers the growth of gastric cancer tumors.</p>
    Fórmula:C28H35NO3
    Forma y color:Solid
    Peso molecular:433.582
  • Deoxythymidine-5'-triphosphate

    CAS:
    <p>Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.</p>
    Fórmula:C10H17N2O14P3
    Forma y color:Solid
    Peso molecular:482.167
  • 5'-O-DMT-N4-Ac-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Fórmula:C32H32FN3O7
    Forma y color:Solid
    Peso molecular:589.61
  • Suricapavir

    CAS:
    <p>Suricapavir is an effective viral replication inhibitor with antiviral activity.</p>
    Fórmula:C41H29ClF9N9O4S
    Forma y color:Solid
    Peso molecular:950.23
  • SR15006

    CAS:
    <p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>
    Fórmula:C16H20ClN3O4S
    Pureza:99.87%
    Forma y color:Soild
    Peso molecular:385.87
  • N6-Methyladenine

    CAS:
    <p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>
    Fórmula:C6H7N5
    Pureza:99.78%
    Forma y color:Solid
    Peso molecular:149.15
  • Diguanosine 5′-triphosphate

    CAS:
    <p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>
    Fórmula:C20H27N10O18P3
    Forma y color:Solid
    Peso molecular:788.409
  • 5'-O-DMT-rU

    CAS:
    <p>5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.</p>
    Fórmula:C30H30N2O8
    Forma y color:Solid
    Peso molecular:546.57
  • 5'-O-TBDMS-dG

    CAS:
    <p>5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.</p>
    Fórmula:C16H27N5O4Si
    Forma y color:Solid
    Peso molecular:381.50
  • (+)-Glaucarubinone


    <p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>
    Fórmula:C25H34O10
    Forma y color:Solid
    Peso molecular:494.537
  • Clofarabine-5'-diphosphate trisodium


    <p>Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Fórmula:C10H10ClFN5Na3O9P2
    Forma y color:Solid
    Peso molecular:529.58
  • Cy5-dATP


    <p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>
    Fórmula:C47H58N7O19P3S2
    Forma y color:Solid
    Peso molecular:1182.05
  • 5'-O-TBDMS-N2-ibu-dG

    CAS:
    <p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>
    Fórmula:C20H33N5O5Si
    Forma y color:Solid
    Peso molecular:451.59
  • Pyrindamycin A

    CAS:
    <p>Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.</p>
    Fórmula:C26H26ClN3O8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:543.95
  • Mulnitorsen

    CAS:
    <p>Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].</p>
    Fórmula:C172H217N74O82P17S17
    Forma y color:Solid
    Peso molecular:5704.66
  • YL-5092


    <p>YL-5092 is an inhibitor of YT521-B homology (YTH) domain-containing protein 1 (YTHDC1). It inhibits acute myeloid leukemia cells with an IC50 of 0.28-2.87 μM. YL-5092 exhibits antitumor activity in xenograft mice models using MOLM-13 or U937 cells.</p>
    Fórmula:C22H14F3N3O2S
    Forma y color:Solid
    Peso molecular:441.43
  • 5'-O-DMT-N2-DMF-dG

    CAS:
    <p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>
    Fórmula:C34H36N6O6
    Forma y color:Solid
    Peso molecular:624.698
  • N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium

    CAS:
    <p>N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].</p>
    Fórmula:C21H35N12O17P3
    Forma y color:Solid
    Peso molecular:820.49
  • (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor,reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Fórmula:C23H30N6O3S2
    Pureza:99.42%
    Forma y color:Soild
    Peso molecular:502.65
  • wrwycr-NH2 TFA


    <p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>
    Forma y color:Odour Solid
  • IBU-DC Phosphoramidite

    CAS:
    <p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>
    Fórmula:C43H54N5O8P
    Forma y color:Solid
    Peso molecular:799.906
  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    <p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>
    Fórmula:C10H14N5Na2O8P
    Forma y color:Solid
    Peso molecular:409.202
  • ddGTP trisodium


    <p>ddGTP trisodium, a ddNTP, inhibits or serves as a substrate for DNA polymerase α, halting DNA chain elongation.</p>
    Fórmula:C10H13N5Na3O12P3
    Forma y color:Solid
    Peso molecular:557.13
  • TS-002266

    CAS:
    <p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>
    Fórmula:C31H32Cl2N6O5
    Pureza:98.18%
    Forma y color:Soild
    Peso molecular:639.53
  • R-1479

    CAS:
    <p>R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.</p>
    Fórmula:C9H12N6O5
    Pureza:98.11% - 99.95%
    Forma y color:Solid
    Peso molecular:284.23
  • 12R-LOX-IN-2

    CAS:
    <p>12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.</p>
    Fórmula:C19H13NO
    Pureza:99.84%
    Forma y color:Solid
    Peso molecular:271.31
  • Vasoactive intestinal contractor

    CAS:
    <p>Vasoactive intestinal contractor, a novel member of the endothelin family, stimulates a rapid increase in intracellular Ca2+ concentration in fura-2-overexpressed Swiss 3T3 cells [1.</p>
    Fórmula:C116H161N27O32S4
    Forma y color:Solid
    Peso molecular:2573.94
  • 5'-O-TBDMS-Bz-dA

    CAS:
    <p>5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.</p>
    Fórmula:C23H31N5O4Si
    Forma y color:Solid
    Peso molecular:469.617
  • m7GpppAmpG

    CAS:
    <p>M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].</p>
    Fórmula:C32H43N15O24P4
    Forma y color:Solid
    Peso molecular:1145.66
  • Antipain

    CAS:
    <p>Antipain, from Actinomycetes, blocks proteases and combats MNNG-induced genetic changes.</p>
    Fórmula:C27H44N10O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:604.713
  • Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Fórmula:C10H13ClFN5O9P2
    Forma y color:Solid
    Peso molecular:463.64
  • 13-TP


    <p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>
    Fórmula:C12H19F2N6O12P3
    Forma y color:Solid
    Peso molecular:570.23
  • Brr2-IN-2


    <p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>
    Fórmula:C21H25FN4O2
    Forma y color:Solid
    Peso molecular:384.45
  • Thailanstatin C

    CAS:
    <p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>
    Fórmula:C30H46ClNO9
    Forma y color:Solid
    Peso molecular:600.15
  • DG1


    <p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>
    Fórmula:C19H17N5O5S
    Forma y color:Solid
    Peso molecular:427.43
  • 5-Methylcytidine 5′-triphosphate

    CAS:
    <p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>
    Fórmula:C10H18N3O14P3
    Forma y color:Solid
    Peso molecular:497.18
  • Garenoxacin

    CAS:
    <p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>
    Fórmula:C23H20F2N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:426.41
  • BRP


    BRP, a peptide related to BRINP2, exhibits anti-obesity activity through the activation of FOS. It triggers FOS activation in the central nervous system, and its effect is independent of leptin, GLP-1 receptor, and melanocortin 4 receptor.
    Forma y color:Odour Solid
  • Ditercalinium chloride

    CAS:
    <p>Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].</p>
    Fórmula:C46H50Cl2N6O2
    Forma y color:Solid
    Peso molecular:789.83
  • HDAC-IN-85


    <p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>
    Fórmula:C24H27FN4O5
    Forma y color:Solid
    Peso molecular:470.49
  • 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine

    CAS:
    <p>5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.</p>
    Fórmula:C22H31N3O5Si
    Forma y color:Solid
    Peso molecular:445.58
  • RNA binder 1


    <p>RNA binder 1 (Compound 4b) is an RNA-binding agent capable of crossing the blood-brain barrier. It selectively binds to the G-quadruplex structure of the G4C2 repeat sequence RNA of the C9orf72 gene. This compound significantly reduces levels of the toxic polypeptides poly(GA) and poly(GP) in cells derived from amyotrophic lateral sclerosis (ALS) patients, while it has no significant impact on the antisense polypeptide poly(PR), demonstrating selectivity for sense RNA. RNA binder 1 is useful for studying ALS and frontotemporal dementia (FTD).</p>
    Fórmula:C22H20N10S2
    Forma y color:Solid
    Peso molecular:488.13138
  • Nusinersen

    CAS:
    <p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>
    Pureza:98.62%
    Forma y color:Solid
  • N1-Methylpseudouridine-5′-triphosphate tetralithium


    <p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>
    Fórmula:C10H13Li4N2O15P3
    Forma y color:Solid
    Peso molecular:521.9
  • Carboxy-pyridostatin

    CAS:
    <p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>
    Fórmula:C35H34N10O7
    Forma y color:Solid
    Peso molecular:706.71
  • 5'-O-DMT-ibu-dC

    CAS:
    <p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>
    Fórmula:C34H37N3O7
    Forma y color:Solid
    Peso molecular:599.67
  • ML-60218

    CAS:
    <p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>
    Fórmula:C19H15Cl2N3O2S2
    Pureza:98.1%
    Forma y color:Solid
    Peso molecular:452.38
  • 16,16-dimethyl Prostaglandin A1

    CAS:
    <p>16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.</p>
    Fórmula:C22H36O4
    Forma y color:Solid
    Peso molecular:364.526
  • Chrexanthomycin C


    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Fórmula:C31H24O15
    Forma y color:Solid
    Peso molecular:636.51
  • PAT-LM1


    <p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>
    Forma y color:Odour Liquid
  • 5'-O-DMT-Bz-rC

    CAS:
    <p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Fórmula:C37H35N3O8
    Forma y color:Solid
    Peso molecular:649.69
  • 5-Methylcytidine 5′-triphosphate trisodium


    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Fórmula:C10H15N3Na3O14P3
    Forma y color:Solid
    Peso molecular:563.13
  • M7G(3'-OMe-5')pppA(2'-OMe)


    <p>M7G(3'-OMe-5')pppA(2'-OMe) is a cap analogue for mRNA synthesis in vitro.</p>
    Fórmula:C23H33N10O17P3
    Forma y color:Solid
    Peso molecular:814.49
  • GS-443902 trisodium

    CAS:
    <p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>
    Fórmula:C12H16N5O13P3·xNa
    Forma y color:Solid
  • POLRMT-IN-1


    <p>POLRMT-IN-1 (compound S7) is an inhibitor of POLRMT, specifically utilized in cancer-related research.</p>
    Forma y color:Odour Solid
  • Cytidine 5'-diphosphate trisodium salt

    CAS:
    <p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>
    Fórmula:C9H15N3Na3O11P2
    Pureza:99.55%
    Forma y color:White Crystalline Powder
    Peso molecular:472.15
  • Nitrosofolic acid

    CAS:
    <p>Nitrosofolic acid is a folic acid derivaive.</p>
    Fórmula:C19H18N8O7
    Forma y color:Solid
    Peso molecular:470.40
  • Carboxy pyridostatin trifluoroacetate salt


    <p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>
    Fórmula:C37H35F3N10O9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:820.73
  • Xanthosine-5'-Triphosphate

    CAS:
    <p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>
    Fórmula:C10H15N4O15P3
    Forma y color:Solid
    Peso molecular:524.164
  • RNA splicing modulator 1

    CAS:
    <p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>
    Fórmula:C19H20N6OS
    Forma y color:Solid
    Peso molecular:380.47
  • Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Fórmula:C30H50N8O12
    Forma y color:Solid
    Peso molecular:714.764
  • CSN5-IN-2


    <p>CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.</p>
    Forma y color:Odour Solid
  • Pseudorabies virus-IN-1


    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Fórmula:C27H23ClF2N4O2
    Forma y color:Solid
    Peso molecular:508.947
  • 2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium


    <p>2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium, an ATP analog, exhibits robust mixed-type inhibition of poly(AU) synthesis.</p>
    Fórmula:C10H11FLi4N5O12P3
    Forma y color:Solid
    Peso molecular:532.9