Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
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Synucleozid
CAS:<p>Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.</p>Fórmula:C22H20N6Pureza:98%Forma y color:SolidPeso molecular:368.43Glucocorticoid receptor modulator 1
CAS:<p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>Fórmula:C24H23ClN2O4SPureza:99.79%Forma y color:SolidPeso molecular:470.97Bofumustine
CAS:<p>Bofumustine is a chloroethyl nitrosourea with anti tumor properties.</p>Fórmula:C18H21ClN4O9Forma y color:SolidPeso molecular:472.83BMVC
CAS:<p>BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.</p>Fórmula:C28H25I2N3Forma y color:SolidPeso molecular:657.33Picoplatin
CAS:<p>Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.</p>Fórmula:C6H10Cl2N2PtPureza:98%Forma y color:SolidPeso molecular:376.14HHL-6
CAS:<p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>Fórmula:C19H26N2O3Forma y color:SolidPeso molecular:330.42Fozivudine tidoxil
CAS:<p>Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C35H64N5O8PSForma y color:SolidPeso molecular:745.95Werner syndrome RecQ helicase-IN-3
CAS:<p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>Fórmula:C31H30ClF3N8O5Forma y color:SolidPeso molecular:687.072-Fluoroadenine
CAS:<p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>Fórmula:C5H4FN5Pureza:98.84% - 99.62%Forma y color:White To Light Yellow Crystal PowderPeso molecular:153.12D-Xylofuranose, 1,2,3,5-tetraacetate
CAS:<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>Fórmula:C13H18O9Forma y color:SolidPeso molecular:318.28Crisnatol mesylate
CAS:<p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>Fórmula:C24H27NO5SForma y color:SolidPeso molecular:441.54HBV-IN-16
CAS:<p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>Fórmula:C22H20ClNO4Forma y color:SolidPeso molecular:397.85GW8510
CAS:<p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>Fórmula:C21H15N5O3S2Pureza:99.32%Forma y color:SolidPeso molecular:449.51AB-182
CAS:<p>AB-182 is an aziridine derivative with antitumor activity.</p>Fórmula:C11H22N3O4PForma y color:SolidPeso molecular:291.28BPIC
CAS:<p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>Fórmula:C27H20N2O5Forma y color:SolidPeso molecular:452.46HBV-IN-22
CAS:<p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>Fórmula:C26H29N3O2S2Forma y color:SolidPeso molecular:479.66Braco-19 trihydrochloride
CAS:<p>BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.</p>Fórmula:C35H46Cl3N7O2Pureza:98.74%Forma y color:SolidPeso molecular:703.14Datelliptium chloride
CAS:<p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>Fórmula:C23H28ClN3OPureza:98%Forma y color:SolidPeso molecular:397.94UIAA-II-232
CAS:<p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>Fórmula:C20H24FN5O3Forma y color:SolidPeso molecular:401.43RHI002-Me
CAS:<p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>Fórmula:C18H19N3O2S2Pureza:98%Forma y color:SolidPeso molecular:373.49Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Fórmula:C24H31N7Forma y color:SolidPeso molecular:417.55Beaucage reagent
CAS:<p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>Fórmula:C7H4O3S2Pureza:98.50%Forma y color:White To Off-White PowderPeso molecular:200.23CGP 53353
CAS:<p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>Fórmula:C20H13F2N3O2Pureza:98.11%Forma y color:SolidPeso molecular:365.33Homocarbonyltopsentin
CAS:<p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>Fórmula:C21H14N4O3Pureza:98%Forma y color:SolidPeso molecular:370.36Triaziquone
CAS:<p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>Fórmula:C12H13N3O2Forma y color:SolidPeso molecular:231.25Phelorphan
CAS:<p>Phelorphan is an inhibitor of enkephalinase.</p>Fórmula:C20H22N2O4SPureza:98%Forma y color:SolidPeso molecular:386.46MLAF50
CAS:<p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>Fórmula:C15H12I2O4Forma y color:SolidPeso molecular:510.06JFN05510
CAS:<p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>Fórmula:C50H68N7O9PSiForma y color:SolidPeso molecular:970.18BMH-22
CAS:<p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Fórmula:C16H17N3Forma y color:SolidPeso molecular:251.33Phen-DC3
CAS:<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Fórmula:C34H26N6O2Pureza:98%Forma y color:SolidPeso molecular:550.61Zelpolib
CAS:<p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>Fórmula:C22H21N3O5S2Pureza:98.79%Forma y color:SolidPeso molecular:471.55HBV-IN-4
CAS:<p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>Fórmula:C24H19ClFN5O3Forma y color:SolidPeso molecular:479.89AS-136A
CAS:<p>AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.</p>Fórmula:C17H19F3N4O3SPureza:98.52%Forma y color:SolidPeso molecular:416.42HIPP
CAS:<p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>Fórmula:C9H9NO3Forma y color:SolidPeso molecular:179.17HIV-1 inhibitor-43
CAS:<p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>Fórmula:C24H21ClN2O4SForma y color:SolidPeso molecular:468.95360A iodide
CAS:<p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>Fórmula:C27H23I2N5O2Pureza:98%Forma y color:SolidPeso molecular:703.31Cylindrospermopsin
CAS:<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Fórmula:C15H21N5O7SForma y color:SolidPeso molecular:415.42BAY-707
CAS:<p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>Fórmula:C15H20N4O2Pureza:98%Forma y color:SolidPeso molecular:288.34EGFR/HER2/TS-IN-2
CAS:<p>EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).</p>Fórmula:C26H21N7OS2Forma y color:SolidPeso molecular:511.62FLDP-5
CAS:<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Fórmula:C21H21NO5Forma y color:SolidPeso molecular:367.4HBV-IN-21
CAS:<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Fórmula:C17H17FN4OS2Forma y color:SolidPeso molecular:376.4715(S)-HpETE
CAS:<p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47NPD9948
CAS:<p>NPD9948 is a competitive inhibitor of MTH1.</p>Fórmula:C13H14N6Forma y color:SolidPeso molecular:254.29CAY10760
CAS:<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Fórmula:C28H24ClN3O3Forma y color:SolidPeso molecular:485.96BMH-23
CAS:<p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Fórmula:C15H15N3Pureza:98%Forma y color:SolidPeso molecular:237.3ERCC1-XPF-IN-1
CAS:<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Fórmula:C28H32ClN5O2Forma y color:SolidPeso molecular:506.04Halofuginone hydrobromide
CAS:<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Fórmula:C16H17BrClN3O3·HBrPureza:97.01% - 99.73%Forma y color:SolidPeso molecular:495.59Enocitabine
CAS:<p>Enocitabine is a nucleoside analog.</p>Fórmula:C31H55N3O6Pureza:97.22%Forma y color:SolidPeso molecular:565.78cp028
CAS:<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Fórmula:C23H17FN2O4Forma y color:SolidPeso molecular:404.39IACS-4759
CAS:<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Fórmula:C10H17N3O2Forma y color:SolidPeso molecular:211.265,10-Dideazaaminopterin
CAS:<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Fórmula:C21H22N6O5Pureza:98%Forma y color:SolidPeso molecular:438.44HBV-IN-14
CAS:<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Fórmula:C22H21ClN2O5Forma y color:SolidPeso molecular:428.87MMV688845
CAS:<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Fórmula:C24H25N3O3SForma y color:SolidPeso molecular:435.54BMVC2
CAS:<p>BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.</p>Fórmula:C28H25I2N3Forma y color:SolidPeso molecular:657.33CB 3717
CAS:<p>CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.</p>Fórmula:C24H23N5O6Forma y color:SolidPeso molecular:477.47CBL 0100 free base
CAS:<p>CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.</p>Fórmula:C24H26N2O2Pureza:98.18% - 98.86%Forma y color:SolidPeso molecular:374.48Antitumor agent-85
<p>Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.</p>Fórmula:C24H33N7Forma y color:SolidPeso molecular:419.57NSC666715
CAS:<p>NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.</p>Fórmula:C15H13Cl2N5O2S2Pureza:98%Forma y color:SolidPeso molecular:430.33Antibacterial agent 124
CAS:<p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>Fórmula:C16H17ClFN3O2Forma y color:SolidPeso molecular:337.78HBV-IN-15
CAS:<p>HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.</p>Fórmula:C24H23ClO6Forma y color:SolidPeso molecular:442.89REV7/REV3L-IN-1
CAS:<p>REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),</p>Fórmula:C19H21N3O3SPureza:98%Forma y color:SolidPeso molecular:371.45ML372
CAS:<p>ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.</p>Fórmula:C18H20N2O4SForma y color:SolidPeso molecular:360.43SMN-C2
CAS:<p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>Fórmula:C24H27N5O2Pureza:99.14%Forma y color:SolidPeso molecular:417.5CHD1Li 6.11
CAS:<p>CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.</p>Fórmula:C21H22BrN5OSPureza:99.04%Forma y color:SolidPeso molecular:472.4ERCC1-XPF-IN-2
CAS:<p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>Fórmula:C15H13Cl2NO3Pureza:98.21%Forma y color:SolidPeso molecular:326.17DDRI-18
CAS:<p>DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.</p>Fórmula:C26H20N6Pureza:98%Forma y color:SolidPeso molecular:416.48ZIM
CAS:<p>ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.</p>Fórmula:C20H19N3O3Pureza:99.85%Forma y color:SolidPeso molecular:349.38Cytembena
CAS:<p>Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.</p>Fórmula:C11H8BrNaO4Pureza:99.35%Forma y color:White PowderPeso molecular:307.07TTP-8307
CAS:<p>TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.</p>Fórmula:C27H21FN4OPureza:98.95%Forma y color:SolidPeso molecular:436.48Caracemide
CAS:<p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>Fórmula:C6H11N3O4Pureza:99.8%Forma y color:SolidPeso molecular:189.17116-9e
CAS:<p>116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.</p>Fórmula:C31H32N2O5Pureza:99.55%Forma y color:SolidPeso molecular:512.66-Hydroxy-DOPA
CAS:<p>6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.</p>Fórmula:C9H11NO5Pureza:97.78% - 97.95%Forma y color:SolidPeso molecular:213.19Anticancer agent 73
CAS:<p>Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.</p>Fórmula:C14H15NO4Pureza:99.19%Forma y color:SolidPeso molecular:261.27D-I03
CAS:<p>D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.</p>Fórmula:C23H36N6SPureza:99.65%Forma y color:SolidPeso molecular:428.64Galocitabine
CAS:<p>Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.</p>Fórmula:C19H22FN3O8Pureza:99.89%Forma y color:SolidPeso molecular:439.39RP-6685
CAS:<p>RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.</p>Fórmula:C22H14F7N5OPureza:99.65%Forma y color:SoildPeso molecular:497.37Talviraline
CAS:<p>Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a</p>Fórmula:C15H20N2O3S2Pureza:99.82%Forma y color:SolidPeso molecular:340.46AVG-233
CAS:<p>AVG-233 is an RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity for the study of respiratory syncytial virus infections.</p>Fórmula:C26H22ClN5O3Pureza:99%Forma y color:SolidPeso molecular:487.94DNA polymerase-IN-3
CAS:<p>DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in</p>Fórmula:C13H12O4Pureza:98%Forma y color:SolidPeso molecular:232.23Votoplam
CAS:<p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>Fórmula:C21H25N9OPureza:98%Forma y color:SolidPeso molecular:419.485,6,7,8-Tetrahydro-8-deazahomofolic acid
CAS:<p>5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>Fórmula:C21H26N6O6Forma y color:SolidPeso molecular:458.475-DACTHF
CAS:<p>5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.</p>Fórmula:C19H24N6O6Pureza:98%Forma y color:SolidPeso molecular:432.43Diazoketone methotrexate
CAS:<p>Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.</p>Fórmula:C21H22N10O4Forma y color:SolidPeso molecular:478.46TAS-114
CAS:<p>TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.</p>Fórmula:C21H29N3O6SPureza:99.76%Forma y color:SolidPeso molecular:451.54WRN inhibitor 3
CAS:<p>WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Fórmula:C20H20N2O5SForma y color:SolidPeso molecular:400.45UNC-2170
CAS:<p>UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.</p>Fórmula:C14H21BrN2OPureza:97.44%Forma y color:SolidPeso molecular:313.23BVDU 5′-Triphosphate
CAS:<p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>Fórmula:C11H16BrN2O14P3Pureza:98%Forma y color:SolidPeso molecular:573.088-Azahypoxanthine
CAS:<p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>Fórmula:C4H3N5OPureza:99.66%Forma y color:Light Yellow To Light Beige Fine CrystallinePeso molecular:137.19-Deazaguanine
CAS:<p>9-Deazaguanine is a nucleoside analogue exhibiting inhibitory activity against bovine purine nucleoside phosphorylase (PNP).</p>Fórmula:C6H6N4OPureza:98%Forma y color:SolidPeso molecular:150.14WRN inhibitor 1
CAS:<p>WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.</p>Fórmula:C16H13FN2O4SPureza:98%Forma y color:SolidPeso molecular:348.35UNC2170 maleate
CAS:<p>53BP1-binding protein 1 (53BP1) engages with dimethylated lysine 20 on histone 4 (H4K20me2) through its tandem tudor domains within a homodimer configuration, crucial for the DNA damage response. UNC2170, a micromolar 53BP1 ligand, selectively interacts with this site, demonstrating at least 17-fold preference for 53BP1 over similar proteins. This interaction occurs in a pocket formed by the 53BP1's tudor domains. Moreover, UNC2170 acts as an antagonist to 53BP1 in cellular lysates, effectively inhibiting class switch recombination, a process dependent on the functional 53BP1 tudor domain, thus confirming its cellular activity.</p>Fórmula:C14H21BrN2OC4H4O4Forma y color:SolidPeso molecular:429.31DAM-IN-1
CAS:<p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>Fórmula:C16H17NO4Pureza:98%Forma y color:SolidPeso molecular:287.31Pencitabine
CAS:<p>Pen is an oral cancer drug that blocks DNA synthesis by inhibiting key enzymes and integrating into DNA.</p>Fórmula:C15H20F3N3O6Forma y color:SolidPeso molecular:395.33COH1
CAS:<p>COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].</p>Fórmula:C11H10N2O3SPureza:98%Forma y color:SolidPeso molecular:250.27WRN inhibitor 2
CAS:<p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>Fórmula:C15H11F3N2O5S2Pureza:98%Forma y color:SolidPeso molecular:420.38H3B-968
CAS:<p>H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease</p>Fórmula:C22H18F6N4O4SPureza:98%Forma y color:SolidPeso molecular:548.46hDHODH-IN-1
CAS:<p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>Fórmula:C17H14N2O2Pureza:99.97%Forma y color:SolidPeso molecular:278.31RNA polymerase II-IN-1
CAS:<p>RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.</p>Fórmula:C38H53N11O12SPureza:98%Forma y color:SolidPeso molecular:887.96DHX9-IN-6
CAS:<p>DHX9-IN-6 is a highly effective ATP-dependent RNA helicase A (DHX9) inhibitor, used in cancer research.</p>Fórmula:C23H18ClFN4O4S2Pureza:99.71%Forma y color:SolidPeso molecular:533DHX9-IN-4
CAS:<p>DHX9-IN-4 is an ATP-dependent RNA helicase DHX9 inhibitor used in cancer research.</p>Fórmula:C21H22ClN5O4S2Pureza:98.12%Forma y color:SolidPeso molecular:508.01
