Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
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DMTr-TNA-U-amidite
CAS:<p>DMTr-TNA-U-amidite is a Nucleoside Phosphoramidite.</p>Fórmula:C38H45N4O8PForma y color:SolidPeso molecular:716.76Antipain dihydrochloride
CAS:<p>Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes with analgesic activity.</p>Fórmula:C27H46Cl2N10O6Pureza:95%Forma y color:White To Off-White PowderPeso molecular:677.625'-O-DMT-N6-Me-2'-dA
CAS:<p>5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modification effects.</p>Fórmula:C32H33N5O5Forma y color:SolidPeso molecular:567.635'-O-DMT-2'-TBDMS-Uridine
CAS:<p>5’-O-DMT-2’-TBDMS-Uridine is a deoxyribonucleoside used for the oligonucleotide synthesis.</p>Fórmula:C36H44N2O8SiForma y color:SolidPeso molecular:660.83DMTr-MOE-Inosine-3-CED-phosphoramidite
<p>DMTr-MOE-Inosine-3-CED-phosphoramidite is a useful organic compound for research related to life sciences and the catalog number is TNU1574.</p>Forma y color:SolidBPN-15477
CAS:<p>BPN-15477 is a splicing modulator compound (SMC) that which restores correct splicing of exon 20 in ELP1 (Elongator complex protein 1).</p>Fórmula:C12H10ClN5Pureza:99.84%Forma y color:SolidPeso molecular:259.692'-O-MOE-U
CAS:<p>2'-O-MOE-U is a Nucleoside Phosphoramidite; Nucleoside Derivative - 2'-Modified nucleoside.</p>Fórmula:C42H53N4O10PForma y color:SolidPeso molecular:804.86DMT-dG(dmf) Phosphoramidite
CAS:<p>DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer employed for oligonucleotide synthesis.</p>Fórmula:C43H53N8O7PForma y color:SolidPeso molecular:824.92'-MOE-G(iBu)-3'-phosphoramidite
CAS:<p>2'-MOE-G(iBu)-3'-phosphoramidite is a Nucleoside Phosphoramidite;Nucleoside Derivative - 2'-Modified nucleoside;.</p>Fórmula:C47H60N7O10PForma y color:SolidPeso molecular:913.99DMTr-LNA-U-3-CED-phosphoramidite
CAS:<p>Nucleoside Phosphoramidites; Nucleoside Derivatives - LNA-related nucleosides</p>Fórmula:C40H47N4O9PForma y color:SolidPeso molecular:758.8Branaplam hydrochloride
CAS:<p>Branaplam hydrochloride (LMI070; NVS-SM1) is an orally active SMN2 splicing modulator (EC50 20 nM) that also inhibits hERG channels (IC50 6.3 μM).</p>Fórmula:C22H28ClN5O2Pureza:98.45%Forma y color:SolidPeso molecular:429.95HDGFRP2/PSIP1-IN-1
CAS:<p>Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual inhibitor targeting the PWWP domains of Hepatoma-derived Growth Factor Related Protein 2 (HDGFRP2) and its homologue PSIP1. This compound effectively hinders the occurrence and progression of Diffuse Intrinsic Pontine Glioma (DIPG). It demonstrates binding affinity with a Kd value of 7 μM for HDGFRP2, indicative of its efficient ligand efficacy at 0.47. Additionally, Compound BPP exhibits a Kd value of 27 μM when binding to the PSIP1 PWWP domain, and a Kd value of 14 μM against HDGFRP3, confirming its potency as an inhibitor within the HDGFRP2 PWWP subfamily.</p>Fórmula:C8H6BrN3Forma y color:SolidPeso molecular:224.063'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite
CAS:<p>3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite is a Nucleoside Phosphoramidite.</p>Fórmula:C12H5Cl3F3N5O4Forma y color:SolidPeso molecular:446.55Uridine 5'-diphosphate sodium salt
CAS:<p>Uridine 5'-diphosphate sodium, P2Y6 agonist (EC50: 300 nM), P2Y14 antagonist (pEC50: 7.28).</p>Fórmula:C9H11N2Na3O12P2Pureza:98%Forma y color:SolidPeso molecular:470.106RNase L-IN-1
<p>RNase L-IN-1 is an RNase L inhibitor with potential anticancer activity and inhibits viral replication.</p>Fórmula:C27H35FN6O3SPureza:98.55%Forma y color:SolidPeso molecular:542.67DMT-locMeC(bz) phosphoramidite
CAS:<p>Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phorphoramidites</p>Fórmula:C48H54N5O9PForma y color:SolidPeso molecular:875.94ML216
CAS:<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Fórmula:C15H9F4N5OSPureza:98.12%Forma y color:SolidPeso molecular:383.32Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Fórmula:C41H44N4O10SPureza:98.11%Forma y color:SolidPeso molecular:784.87Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Fórmula:C26H26N3NaO5SForma y color:SolidPeso molecular:515.56TH5427 hydrochloride
CAS:<p>TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.</p>Fórmula:C20H21Cl3N8O3Forma y color:SolidPeso molecular:527.79
