Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 710 productos de "Síntesis de ADN / ARN"
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HBV-IN-16
CAS:<p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>Fórmula:C22H20ClNO4Forma y color:SolidPeso molecular:397.85Phen-DC3
CAS:<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Fórmula:C34H26N6O2Pureza:98%Forma y color:SolidPeso molecular:550.61GW8510
CAS:<p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>Fórmula:C21H15N5O3S2Pureza:99.32%Forma y color:SolidPeso molecular:449.51Homocarbonyltopsentin
CAS:<p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>Fórmula:C21H14N4O3Pureza:98%Forma y color:SolidPeso molecular:370.36ST7612AA1
CAS:<p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>Fórmula:C20H27N3O4SPureza:99.71%Forma y color:SolidPeso molecular:405.51Phelorphan
CAS:<p>Phelorphan is an inhibitor of enkephalinase.</p>Fórmula:C20H22N2O4SPureza:98%Forma y color:SolidPeso molecular:386.46TDRL-X80
CAS:<p>TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).</p>Fórmula:C23H15ClN2O6Forma y color:SolidPeso molecular:450.83HIPP
CAS:<p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>Fórmula:C9H9NO3Forma y color:SolidPeso molecular:179.17JFN05510
CAS:<p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>Fórmula:C50H68N7O9PSiForma y color:SolidPeso molecular:970.18NPD9948
CAS:<p>NPD9948 is a competitive inhibitor of MTH1.</p>Fórmula:C13H14N6Forma y color:SolidPeso molecular:254.29Triaziquone
CAS:<p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>Fórmula:C12H13N3O2Forma y color:SolidPeso molecular:231.253'-Deoxyuridine-5'-triphosphate
CAS:<p>3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.</p>Fórmula:C9H15N2O14P3Forma y color:SolidPeso molecular:468.14RHI002-Me
CAS:<p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>Fórmula:C18H19N3O2S2Pureza:98%Forma y color:SolidPeso molecular:373.49Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Fórmula:C7H4O3S2Pureza:98.50%Forma y color:White To Off-White PowderPeso molecular:200.23HIV-1 inhibitor-43
CAS:<p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>Fórmula:C24H21ClN2O4SForma y color:SolidPeso molecular:468.95BMH-22
CAS:<p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Fórmula:C16H17N3Forma y color:SolidPeso molecular:251.33MLAF50
CAS:<p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>Fórmula:C15H12I2O4Forma y color:SolidPeso molecular:510.06Cylindrospermopsin
CAS:<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Fórmula:C15H21N5O7SForma y color:SolidPeso molecular:415.42REV7/REV3L-IN-1
CAS:<p>REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),</p>Fórmula:C19H21N3O3SPureza:98%Forma y color:SolidPeso molecular:371.45HBV-IN-4
CAS:<p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>Fórmula:C24H19ClFN5O3Forma y color:SolidPeso molecular:479.89
