
Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 711 productos de "Síntesis de ADN / ARN"
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EGFR/HER2/TS-IN-2
CAS:<p>EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).</p>Fórmula:C26H21N7OS2Forma y color:SolidPeso molecular:511.6215(S)-HpETE
CAS:<p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47REV7/REV3L-IN-1
CAS:<p>REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),</p>Fórmula:C19H21N3O3SPureza:98%Forma y color:SolidPeso molecular:371.45FLDP-5
CAS:<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Fórmula:C21H21NO5Forma y color:SolidPeso molecular:367.4HBV-IN-21
CAS:<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Fórmula:C17H17FN4OS2Forma y color:SolidPeso molecular:376.47CAY10760
CAS:<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Fórmula:C28H24ClN3O3Forma y color:SolidPeso molecular:485.96BMH-23
CAS:<p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Fórmula:C15H15N3Pureza:98%Forma y color:SolidPeso molecular:237.3Enocitabine
CAS:<p>Enocitabine is a nucleoside analog.</p>Fórmula:C31H55N3O6Pureza:97.22%Forma y color:SolidPeso molecular:565.78Halofuginone hydrobromide
CAS:<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Fórmula:C16H17BrClN3O3·HBrPureza:97.01% - 99.73%Forma y color:SolidPeso molecular:495.59ERCC1-XPF-IN-1
CAS:<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Fórmula:C28H32ClN5O2Forma y color:SolidPeso molecular:506.04TDRL-551
CAS:TDRL-551 is a novel and potent replication protein A (RPA) inhibitor (IC50=18 µM) with potential anticancer activity.TDRL-551 inhibits RPA-DNA interaction andFórmula:C25H23ClIN3O4Pureza:98.09%Forma y color:SolidPeso molecular:591.83Piposulfan
CAS:Piposulfan, a water-insoluble alkylating agent, is used as an antineoplastic and anti-tumor agent.Fórmula:C12H22N2O8S2Forma y color:SolidPeso molecular:386.44cp028
CAS:<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Fórmula:C23H17FN2O4Forma y color:SolidPeso molecular:404.395,10-Dideazaaminopterin
CAS:<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Fórmula:C21H22N6O5Pureza:98%Forma y color:SolidPeso molecular:438.44IACS-4759
CAS:<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Fórmula:C10H17N3O2Forma y color:SolidPeso molecular:211.26HBV-IN-14
CAS:<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Fórmula:C22H21ClN2O5Forma y color:SolidPeso molecular:428.87AB-182
CAS:<p>AB-182 is an aziridine derivative with antitumor activity.</p>Fórmula:C11H22N3O4PForma y color:SolidPeso molecular:291.28BMVC2
CAS:<p>BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.</p>Fórmula:C28H25I2N3Forma y color:SolidPeso molecular:657.33MMV688845
CAS:<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Fórmula:C24H25N3O3SForma y color:SolidPeso molecular:435.54CBL 0100 free base
CAS:<p>CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.</p>Fórmula:C24H26N2O2Pureza:98.18% - 98.86%Forma y color:SolidPeso molecular:374.48
