Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
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Polθ-IN-6
CAS:<p>Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.</p>Fórmula:C25H23N3O3SForma y color:SolidPeso molecular:445.53GSK_WRN4
CAS:<p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>Fórmula:C16H20N2O4SPureza:99.95%Forma y color:SolidPeso molecular:336.41Plevitrexed
CAS:<p>Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor & reduced folate carrier, treats gastric cancer.</p>Fórmula:C26H25FN8O4Pureza:98%Forma y color:SolidPeso molecular:532.53Zorubicin
CAS:<p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>Fórmula:C34H35N3O10Forma y color:SolidPeso molecular:645.66Dencatistat
CAS:<p>Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.</p>Fórmula:C24H27N7O5SPureza:98.85%Forma y color:SolidPeso molecular:525.58Methyl 3-oxodecanoate
CAS:<p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>Fórmula:C11H20O3Forma y color:SolidPeso molecular:200.275(R)-CSN5i-3
CAS:<p>(R)-CSN5i-3 is CSN5i-3 of the R configuration.</p>Fórmula:C28H29F2N5O2Pureza:99.76% - 99.97%Forma y color:SolidPeso molecular:505.56Epolactaene
CAS:<p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.</p>Fórmula:C21H27NO6Forma y color:SolidPeso molecular:389.44DIDS
CAS:<p>DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.</p>Fórmula:C16H10N2O6S4Pureza:98%Forma y color:SolidPeso molecular:454.52DHX9-IN-19
CAS:<p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>Fórmula:C20H21ClN4O4S2Forma y color:SolidPeso molecular:480.9885-Methylcytosine hydrochloride
CAS:<p>5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.</p>Fórmula:C5H8ClN3OForma y color:SolidPeso molecular:161.59L-2'-Fd4C
CAS:<p>L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].</p>Fórmula:C9H10FN3O3Forma y color:SolidPeso molecular:227.19Ladirubicin
CAS:<p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>Fórmula:C29H31NO11SForma y color:SolidPeso molecular:601.62Pol I-IN-1
<p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>Fórmula:C23H22N4O2Forma y color:SolidPeso molecular:386.45Antiviral agent 67
CAS:<p>Antiviralagent 67 (compound PC6) is an inhibitor of DENVNS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM.</p>Fórmula:C19H19N3OForma y color:SolidPeso molecular:305.374CB 30900
CAS:<p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>Fórmula:C31H32FN5O9Forma y color:SolidPeso molecular:637.61DENV-IN-6
CAS:<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Fórmula:C23H26ClFN4OSForma y color:SolidPeso molecular:461Polθ-IN-8
CAS:<p>Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.</p>Fórmula:C22H22ClN7O3SForma y color:SolidPeso molecular:499.972'-(2-Nitrobenzyl)-ATP
CAS:<p>2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.</p>Fórmula:C17H21N6O15P3Forma y color:SolidPeso molecular:642.30RAD51-IN-6
CAS:<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Fórmula:C27H40N3O5PSForma y color:SolidPeso molecular:549.66
