Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
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Clofarabine-5'-triphosphate
CAS:<p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>Fórmula:C10H14ClFN5O12P3Forma y color:SolidPeso molecular:543.625'-O-TBDMS-dA
CAS:<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C16H27N5O3SiForma y color:SolidPeso molecular:365.509Cytarabine triphosphate
CAS:<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Fórmula:C9H16N3O14P3Forma y color:SolidPeso molecular:483.16Ac-dA Phosphoramidite
CAS:<p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Fórmula:C42H50N7O7PForma y color:SolidPeso molecular:795.8785'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:<p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C38H47N3O8SiForma y color:SolidPeso molecular:701.89213-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Fórmula:C12H19F2N6O12P3Forma y color:SolidPeso molecular:570.235'-O-TBDMS-Bz-dA
CAS:<p>5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.</p>Fórmula:C23H31N5O4SiForma y color:SolidPeso molecular:469.617Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Fórmula:C21H25FN4O2Forma y color:SolidPeso molecular:384.45Deoxythymidine-5'-triphosphate
CAS:<p>Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.</p>Fórmula:C10H17N2O14P3Forma y color:SolidPeso molecular:482.167Phen-DC3 Trifluoromethanesulfonate
CAS:<p>Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.</p>Fórmula:C36H26F6N6O8S2Pureza:98%Forma y color:SolidPeso molecular:848.75Thailanstatin C
CAS:<p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>Fórmula:C30H46ClNO9Forma y color:SolidPeso molecular:600.155'-O-TBDMS-N2-ibu-dG
CAS:<p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>Fórmula:C20H33N5O5SiForma y color:SolidPeso molecular:451.59CTP Synthetase-IN-1 Ammonium salt
<p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>Fórmula:C20H22F3N7O3S2Pureza:99.97%Forma y color:SolidPeso molecular:529.56Garenoxacin
CAS:<p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>Fórmula:C23H20F2N2O4Pureza:98%Forma y color:SolidPeso molecular:426.41Pyrindamycin A
CAS:<p>Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.</p>Fórmula:C26H26ClN3O8Pureza:98%Forma y color:SolidPeso molecular:543.95Carboxy pyridostatin trifluoroacetate salt
<p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>Fórmula:C37H35F3N10O9Pureza:98%Forma y color:SolidPeso molecular:820.73EFdA-TP
CAS:<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Fórmula:C12H15FN5O12P3Forma y color:SolidPeso molecular:533.195(+)-Glaucarubinone
<p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>Fórmula:C25H34O10Forma y color:SolidPeso molecular:494.537ML-60218
CAS:<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Fórmula:C19H15Cl2N3O2S2Pureza:98.1%Forma y color:SolidPeso molecular:452.385'-O-TBDMS-dG
CAS:<p>5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.</p>Fórmula:C16H27N5O4SiForma y color:SolidPeso molecular:381.50
