Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 708 productos de "Síntesis de ADN / ARN"
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KWR137
<p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>Fórmula:C33H31ClF3N9O4Forma y color:SolidPeso molecular:710.105Cytarabine triphosphate
CAS:<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Fórmula:C9H16N3O14P3Forma y color:SolidPeso molecular:483.16AV-153
CAS:<p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>Fórmula:C14H19NNaO6Forma y color:SolidPeso molecular:320.297m7GpppGmpG
CAS:<p>m7GpppGmpG, a trinucleotide 5′ cap analog, exhibits capping efficiencies of 86% for the RNAs obtained [1].</p>Fórmula:C32H43N15O25P4Forma y color:SolidPeso molecular:1161.66RNA splicing modulator 2
CAS:<p>RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .</p>Fórmula:C20H21N5OSForma y color:SolidPeso molecular:379.48Cy5-dATP
<p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>Fórmula:C47H58N7O19P3S2Forma y color:SolidPeso molecular:1182.05EFdA-TP
CAS:<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Fórmula:C12H15FN5O12P3Forma y color:SolidPeso molecular:533.1955'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:<p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C38H47N3O8SiForma y color:SolidPeso molecular:701.8925-Iminodaunorubicin
CAS:<p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>Fórmula:C27H30N2O9Forma y color:SolidPeso molecular:526.54Chrexanthomycin C
<p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>Fórmula:C31H24O15Forma y color:SolidPeso molecular:636.51RNA polymerase II-IN-2
<p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>Fórmula:C41H58N10O12SForma y color:SolidPeso molecular:915.02Thailanstatin C
CAS:<p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>Fórmula:C30H46ClNO9Forma y color:SolidPeso molecular:600.15Pseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Fórmula:C27H23ClF2N4O2Forma y color:SolidPeso molecular:508.9475'-O-DMT-N4-Ac-2'-F-dC
CAS:<p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C32H32FN3O7Forma y color:SolidPeso molecular:589.613'Ome-m7GpppAmpG
CAS:<p>3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.</p>Fórmula:C33H45N15O24P4Forma y color:SolidPeso molecular:1159.695'-O-DMT-N4-Bz-2'-F-dC
CAS:<p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>Fórmula:C37H34FN3O7Forma y color:SolidPeso molecular:651.68(S)-DI-87
CAS:<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Fórmula:C23H30N6O3S2Pureza:99.42%Forma y color:SoildPeso molecular:502.65Ac-dA Phosphoramidite
CAS:<p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Fórmula:C42H50N7O7PForma y color:SolidPeso molecular:795.878SR15006
CAS:<p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>Fórmula:C16H20ClN3O4SPureza:99.87%Forma y color:SoildPeso molecular:385.875'-O-DMT-PAC-dA
CAS:<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C39H37N5O7Forma y color:SolidPeso molecular:687.74
