Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 708 productos de "Síntesis de ADN / ARN"
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EFdA-TP
CAS:<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Fórmula:C12H15FN5O12P3Forma y color:SolidPeso molecular:533.195Ribonuclease T1
CAS:<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Forma y color:Solid5'-O-DMT-N2-DMF-dG
CAS:<p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>Fórmula:C34H36N6O6Forma y color:SolidPeso molecular:624.698FF-10502
CAS:<p>FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.</p>Fórmula:C9H12FN3O3SForma y color:SolidPeso molecular:261.275'-O-TBDMS-dU
CAS:<p>5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.</p>Fórmula:C15H26N2O5SiForma y color:SolidPeso molecular:342.467EFdA-TP tetraammonium
<p>EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.</p>Fórmula:C12H27N9O12P3Forma y color:SolidPeso molecular:601.31RNA splicing modulator 1
CAS:<p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>Fórmula:C19H20N6OSForma y color:SolidPeso molecular:380.4713-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Fórmula:C12H19F2N6O12P3Forma y color:SolidPeso molecular:570.23Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Fórmula:C21H25FN4O2Forma y color:SolidPeso molecular:384.45Thailanstatin C
CAS:<p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>Fórmula:C30H46ClNO9Forma y color:SolidPeso molecular:600.15Ac-rC Phosphoramidite
CAS:<p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>Fórmula:C47H64N5O9PSiPureza:98.29%Forma y color:SolidPeso molecular:902.15'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:<p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C38H47N3O8SiForma y color:SolidPeso molecular:701.892Garenoxacin
CAS:<p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>Fórmula:C23H20F2N2O4Pureza:98%Forma y color:SolidPeso molecular:426.41N2-Acetylguanine
CAS:<p>Compound 19962-37-9, with CAS No. 19962-37-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 19962-37-9 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C7H7N5O2Pureza:99.90%Forma y color:White SolidPeso molecular:193.166Clofarabine-5'-diphosphate
CAS:<p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>Fórmula:C10H13ClFN5O9P2Forma y color:SolidPeso molecular:463.64Bromochloroacetonitrile
CAS:<p>Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.</p>Fórmula:C2HBrClNForma y color:SolidPeso molecular:154.395'-O-TBDMS-dA
CAS:<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C16H27N5O3SiForma y color:SolidPeso molecular:365.5095'-O-DMT-ibu-dC
CAS:<p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>Fórmula:C34H37N3O7Forma y color:SolidPeso molecular:599.67Nusinersen
CAS:<p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>Pureza:98.62%Forma y color:Solid7-TFA-ap-7-Deaza-ddG
CAS:<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Fórmula:C16H16F3N5O4Forma y color:SolidPeso molecular:399.33
