Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Synucleozid
CAS:<p>Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.</p>Fórmula:C22H20N6Pureza:98%Forma y color:SolidPeso molecular:368.43Glucocorticoid receptor modulator 1
CAS:<p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>Fórmula:C24H23ClN2O4SPureza:99.79%Forma y color:SolidPeso molecular:470.97Bofumustine
CAS:<p>Bofumustine is a chloroethyl nitrosourea with anti tumor properties.</p>Fórmula:C18H21ClN4O9Forma y color:SolidPeso molecular:472.83BMVC
CAS:<p>BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.</p>Fórmula:C28H25I2N3Forma y color:SolidPeso molecular:657.33Picoplatin
CAS:<p>Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.</p>Fórmula:C6H10Cl2N2PtPureza:98%Forma y color:SolidPeso molecular:376.14HHL-6
CAS:<p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>Fórmula:C19H26N2O3Forma y color:SolidPeso molecular:330.42Fozivudine tidoxil
CAS:<p>Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C35H64N5O8PSForma y color:SolidPeso molecular:745.95Werner syndrome RecQ helicase-IN-3
CAS:<p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>Fórmula:C31H30ClF3N8O5Forma y color:SolidPeso molecular:687.072-Fluoroadenine
CAS:<p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>Fórmula:C5H4FN5Pureza:98.84% - 99.62%Forma y color:White To Light Yellow Crystal PowderPeso molecular:153.12D-Xylofuranose, 1,2,3,5-tetraacetate
CAS:<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>Fórmula:C13H18O9Forma y color:SolidPeso molecular:318.28Crisnatol mesylate
CAS:<p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>Fórmula:C24H27NO5SForma y color:SolidPeso molecular:441.54HBV-IN-16
CAS:<p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>Fórmula:C22H20ClNO4Forma y color:SolidPeso molecular:397.85GW8510
CAS:<p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>Fórmula:C21H15N5O3S2Pureza:99.32%Forma y color:SolidPeso molecular:449.51AB-182
CAS:<p>AB-182 is an aziridine derivative with antitumor activity.</p>Fórmula:C11H22N3O4PForma y color:SolidPeso molecular:291.28BPIC
CAS:<p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>Fórmula:C27H20N2O5Forma y color:SolidPeso molecular:452.46HBV-IN-22
CAS:<p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>Fórmula:C26H29N3O2S2Forma y color:SolidPeso molecular:479.66Braco-19 trihydrochloride
CAS:<p>BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.</p>Fórmula:C35H46Cl3N7O2Pureza:98.74%Forma y color:SolidPeso molecular:703.14Datelliptium chloride
CAS:<p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>Fórmula:C23H28ClN3OPureza:98%Forma y color:SolidPeso molecular:397.94UIAA-II-232
CAS:<p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>Fórmula:C20H24FN5O3Forma y color:SolidPeso molecular:401.43RHI002-Me
CAS:<p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>Fórmula:C18H19N3O2S2Pureza:98%Forma y color:SolidPeso molecular:373.49Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Fórmula:C24H31N7Forma y color:SolidPeso molecular:417.55Beaucage reagent
CAS:<p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>Fórmula:C7H4O3S2Pureza:98.50%Forma y color:White To Off-White PowderPeso molecular:200.23CGP 53353
CAS:<p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>Fórmula:C20H13F2N3O2Pureza:98.11%Forma y color:SolidPeso molecular:365.33Homocarbonyltopsentin
CAS:<p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>Fórmula:C21H14N4O3Pureza:98%Forma y color:SolidPeso molecular:370.36Triaziquone
CAS:<p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>Fórmula:C12H13N3O2Forma y color:SolidPeso molecular:231.25Phelorphan
CAS:<p>Phelorphan is an inhibitor of enkephalinase.</p>Fórmula:C20H22N2O4SPureza:98%Forma y color:SolidPeso molecular:386.46MLAF50
CAS:<p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>Fórmula:C15H12I2O4Forma y color:SolidPeso molecular:510.06JFN05510
CAS:<p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>Fórmula:C50H68N7O9PSiForma y color:SolidPeso molecular:970.18BMH-22
CAS:<p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Fórmula:C16H17N3Forma y color:SolidPeso molecular:251.33Phen-DC3
CAS:<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Fórmula:C34H26N6O2Pureza:98%Forma y color:SolidPeso molecular:550.61Zelpolib
CAS:<p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>Fórmula:C22H21N3O5S2Pureza:98.79%Forma y color:SolidPeso molecular:471.55HBV-IN-4
CAS:<p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>Fórmula:C24H19ClFN5O3Forma y color:SolidPeso molecular:479.89AS-136A
CAS:<p>AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.</p>Fórmula:C17H19F3N4O3SPureza:98.52%Forma y color:SolidPeso molecular:416.42HIPP
CAS:<p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>Fórmula:C9H9NO3Forma y color:SolidPeso molecular:179.17HIV-1 inhibitor-43
CAS:<p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>Fórmula:C24H21ClN2O4SForma y color:SolidPeso molecular:468.95360A iodide
CAS:<p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>Fórmula:C27H23I2N5O2Pureza:98%Forma y color:SolidPeso molecular:703.31Cylindrospermopsin
CAS:<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Fórmula:C15H21N5O7SForma y color:SolidPeso molecular:415.42BAY-707
CAS:<p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>Fórmula:C15H20N4O2Pureza:98%Forma y color:SolidPeso molecular:288.34EGFR/HER2/TS-IN-2
CAS:<p>EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).</p>Fórmula:C26H21N7OS2Forma y color:SolidPeso molecular:511.62FLDP-5
CAS:<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Fórmula:C21H21NO5Forma y color:SolidPeso molecular:367.4HBV-IN-21
CAS:<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Fórmula:C17H17FN4OS2Forma y color:SolidPeso molecular:376.4715(S)-HpETE
CAS:<p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47NPD9948
CAS:<p>NPD9948 is a competitive inhibitor of MTH1.</p>Fórmula:C13H14N6Forma y color:SolidPeso molecular:254.29CAY10760
CAS:<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Fórmula:C28H24ClN3O3Forma y color:SolidPeso molecular:485.96BMH-23
CAS:<p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Fórmula:C15H15N3Pureza:98%Forma y color:SolidPeso molecular:237.3ERCC1-XPF-IN-1
CAS:<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Fórmula:C28H32ClN5O2Forma y color:SolidPeso molecular:506.04Halofuginone hydrobromide
CAS:<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Fórmula:C16H17BrClN3O3·HBrPureza:97.01% - 99.73%Forma y color:SolidPeso molecular:495.59Enocitabine
CAS:<p>Enocitabine is a nucleoside analog.</p>Fórmula:C31H55N3O6Pureza:97.22%Forma y color:SolidPeso molecular:565.78cp028
CAS:<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Fórmula:C23H17FN2O4Forma y color:SolidPeso molecular:404.39IACS-4759
CAS:<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Fórmula:C10H17N3O2Forma y color:SolidPeso molecular:211.26
