Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
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5,10-Dideazaaminopterin
CAS:<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Fórmula:C21H22N6O5Pureza:98%Forma y color:SolidPeso molecular:438.44HBV-IN-14
CAS:<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Fórmula:C22H21ClN2O5Forma y color:SolidPeso molecular:428.87MMV688845
CAS:<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Fórmula:C24H25N3O3SForma y color:SolidPeso molecular:435.54BMVC2
CAS:<p>BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.</p>Fórmula:C28H25I2N3Forma y color:SolidPeso molecular:657.33CB 3717
CAS:<p>CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.</p>Fórmula:C24H23N5O6Forma y color:SolidPeso molecular:477.47CBL 0100 free base
CAS:<p>CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.</p>Fórmula:C24H26N2O2Pureza:98.18% - 98.86%Forma y color:SolidPeso molecular:374.48Antitumor agent-85
<p>Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.</p>Fórmula:C24H33N7Forma y color:SolidPeso molecular:419.57NSC666715
CAS:<p>NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.</p>Fórmula:C15H13Cl2N5O2S2Pureza:98%Forma y color:SolidPeso molecular:430.33Antibacterial agent 124
CAS:<p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>Fórmula:C16H17ClFN3O2Forma y color:SolidPeso molecular:337.78HBV-IN-15
CAS:<p>HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.</p>Fórmula:C24H23ClO6Forma y color:SolidPeso molecular:442.89REV7/REV3L-IN-1
CAS:<p>REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),</p>Fórmula:C19H21N3O3SPureza:98%Forma y color:SolidPeso molecular:371.45ML372
CAS:<p>ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.</p>Fórmula:C18H20N2O4SForma y color:SolidPeso molecular:360.43SMN-C2
CAS:<p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>Fórmula:C24H27N5O2Pureza:99.14%Forma y color:SolidPeso molecular:417.5CHD1Li 6.11
CAS:<p>CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.</p>Fórmula:C21H22BrN5OSPureza:99.04%Forma y color:SolidPeso molecular:472.4ERCC1-XPF-IN-2
CAS:<p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>Fórmula:C15H13Cl2NO3Pureza:98.21%Forma y color:SolidPeso molecular:326.17DDRI-18
CAS:<p>DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.</p>Fórmula:C26H20N6Pureza:98%Forma y color:SolidPeso molecular:416.48ZIM
CAS:<p>ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.</p>Fórmula:C20H19N3O3Pureza:99.85%Forma y color:SolidPeso molecular:349.38Cytembena
CAS:<p>Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.</p>Fórmula:C11H8BrNaO4Pureza:99.35%Forma y color:White PowderPeso molecular:307.07TTP-8307
CAS:<p>TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.</p>Fórmula:C27H21FN4OPureza:98.95%Forma y color:SolidPeso molecular:436.48Caracemide
CAS:<p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>Fórmula:C6H11N3O4Pureza:99.8%Forma y color:SolidPeso molecular:189.17116-9e
CAS:<p>116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.</p>Fórmula:C31H32N2O5Pureza:99.55%Forma y color:SolidPeso molecular:512.66-Hydroxy-DOPA
CAS:<p>6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.</p>Fórmula:C9H11NO5Pureza:97.78% - 97.95%Forma y color:SolidPeso molecular:213.19Anticancer agent 73
CAS:<p>Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.</p>Fórmula:C14H15NO4Pureza:99.19%Forma y color:SolidPeso molecular:261.27D-I03
CAS:<p>D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.</p>Fórmula:C23H36N6SPureza:99.65%Forma y color:SolidPeso molecular:428.64Galocitabine
CAS:<p>Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.</p>Fórmula:C19H22FN3O8Pureza:99.89%Forma y color:SolidPeso molecular:439.39RP-6685
CAS:<p>RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.</p>Fórmula:C22H14F7N5OPureza:99.65%Forma y color:SoildPeso molecular:497.37Talviraline
CAS:<p>Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a</p>Fórmula:C15H20N2O3S2Pureza:99.82%Forma y color:SolidPeso molecular:340.46AVG-233
CAS:<p>AVG-233 is an RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity for the study of respiratory syncytial virus infections.</p>Fórmula:C26H22ClN5O3Pureza:99%Forma y color:SolidPeso molecular:487.94DNA polymerase-IN-3
CAS:<p>DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in</p>Fórmula:C13H12O4Pureza:98%Forma y color:SolidPeso molecular:232.23Votoplam
CAS:<p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>Fórmula:C21H25N9OPureza:98%Forma y color:SolidPeso molecular:419.485,6,7,8-Tetrahydro-8-deazahomofolic acid
CAS:<p>5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>Fórmula:C21H26N6O6Forma y color:SolidPeso molecular:458.475-DACTHF
CAS:<p>5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.</p>Fórmula:C19H24N6O6Pureza:98%Forma y color:SolidPeso molecular:432.43Diazoketone methotrexate
CAS:<p>Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.</p>Fórmula:C21H22N10O4Forma y color:SolidPeso molecular:478.46TAS-114
CAS:<p>TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.</p>Fórmula:C21H29N3O6SPureza:99.76%Forma y color:SolidPeso molecular:451.54WRN inhibitor 3
CAS:<p>WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Fórmula:C20H20N2O5SForma y color:SolidPeso molecular:400.45UNC-2170
CAS:<p>UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.</p>Fórmula:C14H21BrN2OPureza:97.44%Forma y color:SolidPeso molecular:313.23BVDU 5′-Triphosphate
CAS:<p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>Fórmula:C11H16BrN2O14P3Pureza:98%Forma y color:SolidPeso molecular:573.088-Azahypoxanthine
CAS:<p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>Fórmula:C4H3N5OPureza:99.66%Forma y color:Light Yellow To Light Beige Fine CrystallinePeso molecular:137.19-Deazaguanine
CAS:<p>9-Deazaguanine is a nucleoside analogue exhibiting inhibitory activity against bovine purine nucleoside phosphorylase (PNP).</p>Fórmula:C6H6N4OPureza:98%Forma y color:SolidPeso molecular:150.14WRN inhibitor 1
CAS:<p>WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.</p>Fórmula:C16H13FN2O4SPureza:98%Forma y color:SolidPeso molecular:348.35UNC2170 maleate
CAS:<p>53BP1-binding protein 1 (53BP1) engages with dimethylated lysine 20 on histone 4 (H4K20me2) through its tandem tudor domains within a homodimer configuration, crucial for the DNA damage response. UNC2170, a micromolar 53BP1 ligand, selectively interacts with this site, demonstrating at least 17-fold preference for 53BP1 over similar proteins. This interaction occurs in a pocket formed by the 53BP1's tudor domains. Moreover, UNC2170 acts as an antagonist to 53BP1 in cellular lysates, effectively inhibiting class switch recombination, a process dependent on the functional 53BP1 tudor domain, thus confirming its cellular activity.</p>Fórmula:C14H21BrN2OC4H4O4Forma y color:SolidPeso molecular:429.31DAM-IN-1
CAS:<p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>Fórmula:C16H17NO4Pureza:98%Forma y color:SolidPeso molecular:287.31Pencitabine
CAS:<p>Pen is an oral cancer drug that blocks DNA synthesis by inhibiting key enzymes and integrating into DNA.</p>Fórmula:C15H20F3N3O6Forma y color:SolidPeso molecular:395.33COH1
CAS:<p>COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].</p>Fórmula:C11H10N2O3SPureza:98%Forma y color:SolidPeso molecular:250.27WRN inhibitor 2
CAS:<p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>Fórmula:C15H11F3N2O5S2Pureza:98%Forma y color:SolidPeso molecular:420.38H3B-968
CAS:<p>H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease</p>Fórmula:C22H18F6N4O4SPureza:98%Forma y color:SolidPeso molecular:548.46hDHODH-IN-1
CAS:<p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>Fórmula:C17H14N2O2Pureza:99.97%Forma y color:SolidPeso molecular:278.31RNA polymerase II-IN-1
CAS:<p>RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.</p>Fórmula:C38H53N11O12SPureza:98%Forma y color:SolidPeso molecular:887.96DHX9-IN-6
CAS:<p>DHX9-IN-6 is a highly effective ATP-dependent RNA helicase A (DHX9) inhibitor, used in cancer research.</p>Fórmula:C23H18ClFN4O4S2Pureza:99.71%Forma y color:SolidPeso molecular:533DHX9-IN-4
CAS:<p>DHX9-IN-4 is an ATP-dependent RNA helicase DHX9 inhibitor used in cancer research.</p>Fórmula:C21H22ClN5O4S2Pureza:98.12%Forma y color:SolidPeso molecular:508.01
