Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
NSC 80467
CAS:<p>NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.</p>Fórmula:C24H22BrN3O5Forma y color:SolidPeso molecular:512.36Nolatrexed dihydrochloride
CAS:<p>Nolatrexed dihydrochloride (Thymitaq) is a soluble, lipophilic cancer drug that inhibits DNA replication, causing cell cycle arrest and apoptosis.</p>Fórmula:C14H14Cl2N4OSPureza:97.02%Forma y color:Tan SolidPeso molecular:357.26DTP3
CAS:<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Fórmula:C26H35N7O5Forma y color:SolidPeso molecular:525.62'-O-Me-C(Bz) Phosphoramidite
CAS:<p>2’-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.</p>Fórmula:C47H54N5O9PForma y color:SolidPeso molecular:863.93Synucleozid hydrochloride
CAS:<p>Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.</p>Fórmula:C22H21ClN6Pureza:98.13%Forma y color:SolidPeso molecular:404.92'-O-MOE-5MeU-3'-phosphoramidite
CAS:<p>2'-O-MOE-5MeU-3'-phosphoramidite is a Nucleoside Phosphoramidite.</p>Fórmula:C43H55N4O10PForma y color:SolidPeso molecular:818.89Bz-rA Phosphoramidite
CAS:<p>Bz-rA Phosphoramidite is used for ribonucleotides modification[1].</p>Fórmula:C53H66N7O8PSiForma y color:SolidPeso molecular:988.192'-O-MOE-5-Me-rU
CAS:<p>2'-O-MOE-5-Me-rU is a Nucleoside Derivative - 2'-Modified nucleoside.</p>Fórmula:C13H20N2O7Forma y color:SolidPeso molecular:316.31Balapiravir
CAS:<p>Balapiravir (R1626) is a prodrug targeting HCV polymerase, discontinued due to safety concerns like lymphopenia and other serious side effects.</p>Fórmula:C21H30N6O8Forma y color:SolidPeso molecular:494.52'-O-MOE-rC
CAS:<p>2'-O-MOE-rC is a Nucleoside Phosphoramidite; Nucleoside Derivative - 2'-Modified nucleoside.</p>Fórmula:C49H58N5O10PForma y color:SolidPeso molecular:907.995'-DMTr-dC (Ac)-methylphosphonamidite
CAS:<p>5'-DMTr-dC (Ac)-methylphosphonamidite is a Nucleoside Derivative - phosphonamidite.</p>Fórmula:C39H49N4O7PForma y color:SolidPeso molecular:716.87-TFA-ap-7-Deaza-dG
CAS:<p>5'-O-TBDMS-dG, a modified nucleoside, is utilized in the synthesis of deoxyribonucleic acid or nucleic acid.</p>Fórmula:C16H16F3N5O5Forma y color:SolidPeso molecular:415.3292',3'-Dideoxy tubercidin
CAS:<p>Nucleoside Derivatives - 7-Deaza-purine nucleosides; 2’,3’-Dideoxy nucleosides</p>Fórmula:C11H14N4O2Forma y color:SolidPeso molecular:234.252'-O,4'-C-Methyleneguanosine
CAS:<p>2'-O,4'-C-Methyleneguanosine is a Nucleoside Derivative - LNA-related nucleoside.</p>Fórmula:C11H13N5O5Forma y color:SolidPeso molecular:295.25Remdesivir O-desphosphate acetonide impurity
CAS:<p>Remdesivir impurity, O-desphosphate acetonide, is a byproduct obstructing its antiviral efficacy against COVID-19.</p>Fórmula:C15H17N5O4Forma y color:SolidPeso molecular:331.332'-O-MOE-5-Me-rC
CAS:<p>2'-O-MOE-5-Me-rC is a Nucleoside Derivative - 2'-Modified nucleoside.</p>Fórmula:C13H21N3O6Forma y color:SolidPeso molecular:315.32Maleic hydrazide
CAS:<p>Maleic hydrazide is a plant germination inhibitor that participates in nucleic acid metabolism pathways ,inhibiting cell division in the apical meristem.</p>Fórmula:C4H4N2O2Pureza:98.4%Forma y color:Crystals From Water Maleic Hydrazide Is An Odorless White Solid Sinks In Water (Uscg 1999)Peso molecular:112.092-Amino-2'-deoxyadenosine
CAS:<p>2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis.</p>Fórmula:C10H14N6O3Forma y color:SolidPeso molecular:266.263'-Deoxy-3'-fluoroguanosine
CAS:<p>3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons.</p>Fórmula:C10H12FN5O4Pureza:99.33%Forma y color:SolidPeso molecular:285.23DMTr-FNA-C(Bz)phosphoramidite
CAS:<p>Nucleoside phosphoramidites；Nucleoside Derivatives - Acyclic nucleosides;</p>Fórmula:C45H52N5O8PForma y color:SolidPeso molecular:821.92'-OMe-A(Bz) Phosphoramidite
CAS:<p>2’-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.</p>Fórmula:C48H54N7O8PForma y color:SolidPeso molecular:887.962'-OMe-G(ibu) Phosphoramidite
CAS:<p>2’-OMe-G(ibu) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.</p>Fórmula:C45H56N7O9PForma y color:SolidPeso molecular:869.947-TFA-ap-7-Deaza-dA
CAS:<p>7-TFA-ap-7-Deaza-dA, a modified nucleoside, finds application in the synthesis of deoxyribonucleic acid or nucleic acid.</p>Fórmula:C16H16F3N5O4Forma y color:SolidPeso molecular:399.335'-O-DMT-3'-O-TBDMS-Ac-rC
CAS:<p>5’-O-DMT-3’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C38H47N3O8SiForma y color:SolidPeso molecular:701.882'-O-MOE-5-Me-C(Bz)
CAS:<p>Nucleoside Phosphoramidites; Ready for phosphorylation</p>Fórmula:C50H60N5O10PForma y color:SolidPeso molecular:922.01DMT-dC(ac) Phosphoramidite
CAS:<p>DMT-dC(ac) Phosphoramidite is a phosphoramidite monomer that has been modified for use in oligonucleotide synthesis.</p>Fórmula:C41H50N5O8PForma y color:SolidPeso molecular:771.84DHPS-IN-1
CAS:<p>DHPS-IN-1, a chemical compound, demonstrates exceptional inhibitory potency against melanoma cells, as evidenced by its IC50 value of 0.014 μM.</p>Fórmula:C17H13BrClN3O2Forma y color:SolidPeso molecular:406.663'-Deoxy-3'-α-C-methyluridine
CAS:<p>3'-Deoxy-3'-alpha-C-methyluridine is a Nucleoside; Used for nucleoside and nucleic acid modifications.</p>Fórmula:C10H14N2O5Forma y color:SolidPeso molecular:242.23Napropamide
CAS:<p>Napropamide is an acetamide herbicide that inhibits root growth to control annual grasses and broadleaf weeds.</p>Fórmula:C17H21NO2Pureza:99.14%Forma y color:Colorless Crystals; (Tech Brown Solid) White-Like CrystalPeso molecular:271.35N6-Methyl-dA phosphoramidite
CAS:<p>N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides.</p>Fórmula:C41H50N7O6PForma y color:SolidPeso molecular:767.85DMTr-TNA-U-amidite
CAS:<p>DMTr-TNA-U-amidite is a Nucleoside Phosphoramidite.</p>Fórmula:C38H45N4O8PForma y color:SolidPeso molecular:716.76Antipain dihydrochloride
CAS:<p>Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes with analgesic activity.</p>Fórmula:C27H46Cl2N10O6Pureza:95%Forma y color:White To Off-White PowderPeso molecular:677.625'-O-DMT-N6-Me-2'-dA
CAS:<p>5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modification effects.</p>Fórmula:C32H33N5O5Forma y color:SolidPeso molecular:567.635'-O-DMT-2'-TBDMS-Uridine
CAS:<p>5’-O-DMT-2’-TBDMS-Uridine is a deoxyribonucleoside used for the oligonucleotide synthesis.</p>Fórmula:C36H44N2O8SiForma y color:SolidPeso molecular:660.83DMTr-MOE-Inosine-3-CED-phosphoramidite
<p>DMTr-MOE-Inosine-3-CED-phosphoramidite is a useful organic compound for research related to life sciences and the catalog number is TNU1574.</p>Forma y color:SolidBPN-15477
CAS:<p>BPN-15477 is a splicing modulator compound (SMC) that which restores correct splicing of exon 20 in ELP1 (Elongator complex protein 1).</p>Fórmula:C12H10ClN5Pureza:99.84%Forma y color:SolidPeso molecular:259.692'-O-MOE-U
CAS:<p>2'-O-MOE-U is a Nucleoside Phosphoramidite; Nucleoside Derivative - 2'-Modified nucleoside.</p>Fórmula:C42H53N4O10PForma y color:SolidPeso molecular:804.86DMT-dG(dmf) Phosphoramidite
CAS:<p>DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer employed for oligonucleotide synthesis.</p>Fórmula:C43H53N8O7PForma y color:SolidPeso molecular:824.92'-MOE-G(iBu)-3'-phosphoramidite
CAS:<p>2'-MOE-G(iBu)-3'-phosphoramidite is a Nucleoside Phosphoramidite;Nucleoside Derivative - 2'-Modified nucleoside;.</p>Fórmula:C47H60N7O10PForma y color:SolidPeso molecular:913.99DMTr-LNA-U-3-CED-phosphoramidite
CAS:<p>Nucleoside Phosphoramidites; Nucleoside Derivatives - LNA-related nucleosides</p>Fórmula:C40H47N4O9PForma y color:SolidPeso molecular:758.8Branaplam hydrochloride
CAS:<p>Branaplam hydrochloride (LMI070; NVS-SM1) is an orally active SMN2 splicing modulator (EC50 20 nM) that also inhibits hERG channels (IC50 6.3 μM).</p>Fórmula:C22H28ClN5O2Pureza:98.45%Forma y color:SolidPeso molecular:429.95HDGFRP2/PSIP1-IN-1
CAS:<p>Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual inhibitor targeting the PWWP domains of Hepatoma-derived Growth Factor Related Protein 2 (HDGFRP2) and its homologue PSIP1. This compound effectively hinders the occurrence and progression of Diffuse Intrinsic Pontine Glioma (DIPG). It demonstrates binding affinity with a Kd value of 7 μM for HDGFRP2, indicative of its efficient ligand efficacy at 0.47. Additionally, Compound BPP exhibits a Kd value of 27 μM when binding to the PSIP1 PWWP domain, and a Kd value of 14 μM against HDGFRP3, confirming its potency as an inhibitor within the HDGFRP2 PWWP subfamily.</p>Fórmula:C8H6BrN3Forma y color:SolidPeso molecular:224.063'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite
CAS:<p>3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite is a Nucleoside Phosphoramidite.</p>Fórmula:C12H5Cl3F3N5O4Forma y color:SolidPeso molecular:446.55Uridine 5'-diphosphate sodium salt
CAS:<p>Uridine 5'-diphosphate sodium, P2Y6 agonist (EC50: 300 nM), P2Y14 antagonist (pEC50: 7.28).</p>Fórmula:C9H11N2Na3O12P2Pureza:98%Forma y color:SolidPeso molecular:470.106RNase L-IN-1
<p>RNase L-IN-1 is an RNase L inhibitor with potential anticancer activity and inhibits viral replication.</p>Fórmula:C27H35FN6O3SPureza:98.55%Forma y color:SolidPeso molecular:542.67DMT-locMeC(bz) phosphoramidite
CAS:<p>Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phorphoramidites</p>Fórmula:C48H54N5O9PForma y color:SolidPeso molecular:875.94ML216
CAS:<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Fórmula:C15H9F4N5OSPureza:98.12%Forma y color:SolidPeso molecular:383.32Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Fórmula:C41H44N4O10SPureza:98.11%Forma y color:SolidPeso molecular:784.87Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Fórmula:C26H26N3NaO5SForma y color:SolidPeso molecular:515.56TH5427 hydrochloride
CAS:<p>TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.</p>Fórmula:C20H21Cl3N8O3Forma y color:SolidPeso molecular:527.79
