Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 708 productos de "Síntesis de ADN / ARN"
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L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Forma y color:SolidPeso molecular:486.11Pseudouridine
CAS:<p>Pseudouridine, prevalent in non-coding RNAs, boosts tRNA and rRNA function by RNA stabilization.</p>Fórmula:C9H12N2O6Pureza:99.3%Forma y color:SolidPeso molecular:244.2Garenoxacin mesylate hydrate
CAS:<p>Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains</p>Fórmula:C23H20F2N2O4·CH4O3S·H2OPureza:99.56%Forma y color:SolidPeso molecular:540.53NSC 617145
CAS:<p>NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent</p>Fórmula:C13H10Cl4N2O4Pureza:99.72%Forma y color:SolidPeso molecular:400.04Gemcitabine hydrochloride
CAS:<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Forma y color:White Crystalline Granular OdorlessPeso molecular:299.66Isoindigotin
CAS:<p>Isoindigotin is used in the therapy of Y.</p>Fórmula:C16H10N2O2Pureza:98.14% - ≥95%Forma y color:SolidPeso molecular:262.26Pyridostatin Trihydrochloride
CAS:<p>Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.</p>Fórmula:C31H35Cl3N8O5Pureza:99.69%Forma y color:SolidPeso molecular:706.02Quinizarin
CAS:<p>Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product</p>Fórmula:C14H8O4Pureza:95.02%Forma y color:Leaves Yellow Red And Needles Dark Red Solid Leaves Or NeedlesPeso molecular:240.21O6-Benzylguanine
CAS:<p>O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.</p>Fórmula:C12H11N5OPureza:98.9%Forma y color:Solid CrystallinePeso molecular:241.25Deoxycytidine triphosphate
CAS:<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Fórmula:C9H16N3O13P3Pureza:99.68%Forma y color:SolidPeso molecular:467.16GS-441524
CAS:<p>GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.</p>Fórmula:C12H13N5O4Pureza:98.78% - 99.75%Forma y color:SolidPeso molecular:291.26Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Fórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Forma y color:SolidPeso molecular:498.4Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Forma y color:SolidPeso molecular:938.71L189
CAS:<p>L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).</p>Fórmula:C11H10N4OSPureza:97.37%Forma y color:SolidPeso molecular:246.29TH588
CAS:<p>TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.</p>Fórmula:C13H12Cl2N4Pureza:96.05% - 99.82%Forma y color:SolidPeso molecular:295.17PfDHODH-IN-1
CAS:<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Fórmula:C14H11F3N2O2Pureza:99.87%Forma y color:SolidPeso molecular:296.24NSAH
CAS:<p>NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-</p>Fórmula:C18H14N2O3Pureza:99.27%Forma y color:SolidPeso molecular:306.32Triciribine
CAS:Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.Fórmula:C13H16N6O4Pureza:99.01% - 99.87%Forma y color:SolidPeso molecular:320.3Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Fórmula:C18H21ClFN3O4Pureza:99.78% - 99.98%Forma y color:SolidPeso molecular:397.8CeMMEC13
CAS:<p>CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).</p>Fórmula:C19H16N2O4Pureza:98.52%Forma y color:SolidPeso molecular:336.34SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Fórmula:C19H13Cl2N3O2SPureza:98.9%Forma y color:SolidPeso molecular:418.3360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Fórmula:C27H23N5O2Pureza:98.68%Forma y color:SolidPeso molecular:449.5PCNA-I1
CAS:<p>PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.</p>Fórmula:C17H14N2O2SPureza:97.64%Forma y color:SolidPeso molecular:310.376-AZATHYMINE
CAS:<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Fórmula:C4H5N3O2Pureza:99.47%Forma y color:SolidPeso molecular:127.1RI-2
CAS:<p>RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.</p>Fórmula:C21H18Cl2N2O4Pureza:99.63% - 99.86%Forma y color:SolidPeso molecular:433.28AT-130
CAS:<p>AT-130: Strong HBV inhibitor (IC50 0.13 μM), low toxicity in HepAD38, hinders RNA packaging.</p>Fórmula:C22H22BrN3O5Pureza:97.81%Forma y color:SolidPeso molecular:488.33CRT0044876
CAS:<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Fórmula:C9H6N2O4Pureza:98.27% - 98.98%Forma y color:Brown PowderPeso molecular:206.15Ro5-3335
CAS:<p>Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.</p>Fórmula:C13H10ClN3OPureza:99.42% - 99.87%Forma y color:SolidPeso molecular:259.69Favipiravir
CAS:<p>Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.</p>Fórmula:C5H4FN3O2Pureza:97.32% - 99.90%Forma y color:SolidPeso molecular:157.1Quarfloxin
CAS:<p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>Fórmula:C35H33FN6O3Pureza:99.77%Forma y color:SolidPeso molecular:604.67Madrasin
CAS:<p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>Fórmula:C16H17N5O2Pureza:99.06% - 99.61%Forma y color:SolidPeso molecular:311.34Nimustine Hydrochloride
CAS:<p>Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.</p>Fórmula:C9H14Cl2N6O2Pureza:98.80%Forma y color:SolidPeso molecular:309.15Cidofovir
CAS:<p>Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。</p>Fórmula:C8H14N3O6PPureza:99.24% - 99.76%Forma y color:Fluffy White PowderPeso molecular:279.19RAD51-IN-1
CAS:<p>Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.</p>Fórmula:C22H16ClN3OPureza:99.95%Forma y color:SolidPeso molecular:373.833-Hydroxy-2-methylpyridine
CAS:<p>3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.</p>Fórmula:C6H7NOPureza:98.96% - 99.03%Forma y color:Beige-Brown PowderPeso molecular:109.13NITD-2
CAS:<p>NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.</p>Fórmula:C23H19N3O4SPureza:98.03% - 99.46%Forma y color:SolidPeso molecular:433.48CBFβ Inhibitor
CAS:<p>CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.</p>Fórmula:C12H14N2OSPureza:96.50%Forma y color:SolidPeso molecular:234.32CX-5461
CAS:<p>CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C27H27N7O2SPureza:95.44% - 99.25%Forma y color:SolidPeso molecular:513.61BVDV-IN-1
CAS:<p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>Fórmula:C20H22N4OPureza:98.43%Forma y color:SolidPeso molecular:334.41Danofloxacin
CAS:<p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>Fórmula:C19H20FN3O3Pureza:99.77% - 99.8%Forma y color:SolidPeso molecular:357.38Cynaroside
CAS:<p>Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.</p>Fórmula:C21H20O11Pureza:98% - >99.99%Forma y color:SolidPeso molecular:448.38Levofloxacin
CAS:<p>Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.</p>Fórmula:C18H20FN3O4Pureza:98.14% - 99.80%Forma y color:Off-White To Yellow CrystalsPeso molecular:361.37Zoliflodacin
CAS:<p>Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.</p>Fórmula:C22H22FN5O7Pureza:99.82% - 99.93%Forma y color:SolidPeso molecular:487.44Tubercidin
CAS:<p>Tubercidin, an adenosine analogue nucleoside antibiotic, hinders DNA/RNA synthesis and possesses antifungal and antiviral properties.</p>Fórmula:C11H14N4O4Pureza:98.66% - >99.99%Forma y color:SolidPeso molecular:266.25Branaplam
CAS:<p>Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.</p>Fórmula:C22H27N5O2Pureza:98.28% - 99.72%Forma y color:SolidPeso molecular:393.485-Methylcytosine
CAS:<p>5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA.</p>Fórmula:C5H7N3OPureza:99.17%Forma y color:SolidPeso molecular:125.13N-Nitrosodiethylamine
CAS:<p>N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine.</p>Fórmula:C4H10N2OPureza:99.26% - 99.88%Forma y color:SolidPeso molecular:102.14Bractoppin
CAS:<p>Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits</p>Fórmula:C25H23FN4OPureza:98.38%Forma y color:SolidPeso molecular:414.47ML264
CAS:<p>ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.</p>Fórmula:C17H21ClN2O4SPureza:99.33% - 99.45%Forma y color:SolidPeso molecular:384.88Didox
CAS:<p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>Fórmula:C7H7NO4Pureza:99.83%Forma y color:SolidPeso molecular:169.13
