Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 800 productos de "Síntesis de ADN / ARN"
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Clofarabine-5'-diphosphate
CAS:Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.Fórmula:C10H13ClFN5O9P2Forma y color:SolidPeso molecular:463.645'-O-DMT-rI
CAS:5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].Fórmula:C31H30N4O7Forma y color:SolidPeso molecular:570.59ddGTP trisodium
ddGTP trisodium, a ddNTP, inhibits or serves as a substrate for DNA polymerase α, halting DNA chain elongation.Fórmula:C10H13N5Na3O12P3Forma y color:SolidPeso molecular:557.135'-O-DMT-N2-DMF-dG
CAS:5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.Fórmula:C34H36N6O6Forma y color:SolidPeso molecular:624.698Guanosine 5'-triphosphate trisodium salt hydrate
CAS:5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.Fórmula:C10H18N5NaO15P3Pureza:98%Forma y color:SolidPeso molecular:564.18523-Oxa-OSW-1
CAS:23-Oxa-OSW-1 (SBF-1), a derivative of OSW-1, serves as a potent inhibitor of the osterol-binding protein (OSBP) with demonstrated antitumor activity [1] [2].Fórmula:C54H82O16Forma y color:SolidPeso molecular:987.22cis-Lomibuvir
CAS:cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.Fórmula:C25H35NO4SForma y color:SolidPeso molecular:445.61VPC-18005
CAS:VPC-18005: a luciferase inhibitor that blocks ERG-induced transcription by binding ERG-ETS, hindering DNA attachment.
Fórmula:C15H17N3O3SPureza:99.95%Forma y color:SoildPeso molecular:319.38Phen-DC3 Trifluoromethanesulfonate
CAS:Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Fórmula:C36H26F6N6O8S2Pureza:98%Forma y color:SolidPeso molecular:848.75Mulnitorsen
CAS:Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].Fórmula:C172H217N74O82P17S17Forma y color:SolidPeso molecular:5704.66Dezecapavir
CAS:Dezecapavir (example 4) acts as an effective inhibitor of viral replication, exhibiting an EC50 value of 0.025 nM in MT2 cells with a CC50 greater than 0.5 μM.Fórmula:C37H29ClF9N9O5SForma y color:SolidPeso molecular:918.195'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.Fórmula:C38H47N3O8SiForma y color:SolidPeso molecular:701.892Guanosine triphosphate
CAS:Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].Fórmula:C10H16N5O14P3Forma y color:SolidPeso molecular:523.1816,16-dimethyl Prostaglandin A1
CAS:16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.Fórmula:C22H36O4Forma y color:SolidPeso molecular:364.5265'-O-DMT-Bz-rC
CAS:5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.Fórmula:C37H35N3O8Forma y color:SolidPeso molecular:649.69EFdA-TP
CAS:EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.Fórmula:C12H15FN5O12P3Forma y color:SolidPeso molecular:533.195wrwyar-NH2 TFA
wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.Forma y color:Odour Solid5-BrdUTP sodium salt
CAS:5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.Fórmula:C9H10BrN2Na4O14P3Pureza:98%Forma y color:SolidPeso molecular:634.97HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
CAS:HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.Fórmula:C57H62N8O10SForma y color:SolidPeso molecular:1051.218-NH2-ATP
CAS:8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.Fórmula:C10H17N6O13P3Forma y color:SolidPeso molecular:522.20
