Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 799 productos de "Síntesis de ADN / ARN"
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DMT-dG(ib) Phosphoramidite
CAS:DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Fórmula:C44H54N7O8PPureza:99.21%Forma y color:SolidPeso molecular:839.92EFdA-TP
CAS:EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.Fórmula:C12H15FN5O12P3Forma y color:SolidPeso molecular:533.195DMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.Fórmula:C47H54N5O8PForma y color:SolidPeso molecular:847.935-Iminodaunorubicin
CAS:5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.Fórmula:C27H30N2O9Forma y color:SolidPeso molecular:526.54IBU-DC Phosphoramidite
CAS:IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.Fórmula:C43H54N5O8PForma y color:SolidPeso molecular:799.906Pseudorabies virus-IN-1
Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.Fórmula:C27H23ClF2N4O2Forma y color:SolidPeso molecular:508.947ONX 0801 trisodium
CAS:ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.Fórmula:C32H30N5Na3O10Forma y color:SolidPeso molecular:713.582'-OMe-Ac-C Phosphoramidite
CAS:2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.Fórmula:C42H52N5O9PForma y color:SolidPeso molecular:801.86Xanthosine-5'-Triphosphate
CAS:Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.
Fórmula:C10H15N4O15P3Forma y color:SolidPeso molecular:524.164N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS:N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].
Fórmula:C21H35N12O17P3Forma y color:SolidPeso molecular:820.49WRN inhibitor 18
CAS:WRN inhibitor 18 (compound 306) is an orally active inhibitor of WRN with demonstrated anticancer activity in vivo.Fórmula:C35H35F6N5O5SForma y color:SolidPeso molecular:751.742'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.Fórmula:C10H14N5Na2O8PForma y color:SolidPeso molecular:409.202wrwycr-NH2 TFA
wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.Forma y color:Odour SolidAp4dT
CAS:Ap4dT serves as an inhibitor of human adenylate kinase isozyme 1 (hAK1), effectively suppressing the synthesis of ATP and ADP, with IC50 values of 42 μM and 38 μM, respectively.Fórmula:C20H41N11O20P4Forma y color:SolidPeso molecular:879.5Deoxythymidine-5'-triphosphate sodium hydrate
dTTP sodium hydrate, a DNA synthesis component, is a nucleoside triphosphate.Fórmula:C10H17N2O14P3·xNa·xH2OForma y color:SolidPeso molecular:C10H17N2O14P3.xNa.xH2ODIZ-3
CAS:DIZ-3: Selective G4 ligand, stabilizes structure, inhibits ALT cancer cell growth by inducing cell cycle arrest and apoptosis.Fórmula:C46H44F2N8Forma y color:SolidPeso molecular:746.89Primordazine NC-6364997
CAS:Primordazine NC-6364997 is a negative control for Primordazine A and Primordazine B.Fórmula:C22H23N5OSForma y color:SolidPeso molecular:405.52(E)-5-(2-Bromovinyl)uracil
CAS:BVU, a pyrimidine and inactive sorivudine metabolite, inactivates DPD, boosts 5-fluorouracil efficacy in leukemia, and may convert back to BVDU in vivo.Fórmula:C6H5BrN2O2Forma y color:SolidPeso molecular:217.02Anticancer agent 262
Anticanceragent 262 (compound 3h) is a DNA-intercalating antineoplastic agent with an IC50 value of 5.7 µM against A549 cancer cells.Fórmula:C26H31N3OForma y color:SolidPeso molecular:401.544Antiviral agent 36
Antiviral agent 36 (compound 27), a potent inhibitor of both dengue (DENV) and Zika (ZIKV) viruses, demonstrates replication inhibition with EC50 values of 100Fórmula:C30H32N4O3Pureza:98%Forma y color:SolidPeso molecular:496.6
