Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 798 productos de "Síntesis de ADN / ARN"
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TH5427 hydrochloride
CAS:TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.Fórmula:C20H21Cl3N8O3Forma y color:SolidPeso molecular:527.79SR18662
SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.Fórmula:C16H19Cl2N3O4SPureza:98.97% - 99.2%Forma y color:SolidPeso molecular:420.31Ref: TM-T22429
1mg46,00€5mg90,00€10mg152,00€25mg295,00€50mg475,00€100mg680,00€200mg888,00€500mg1.378,00€1mL*10mM (DMSO)100,00€Remdesivir
CAS:Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase ofFórmula:C27H35N6O8PPureza:97.62% - 99.98%Forma y color:SolidPeso molecular:602.58Ref: TM-T7766
1mg108,00€5mg205,00€10mg326,00€25mg497,00€50mg663,00€100mg1.063,00€1mL*10mM (DMSO)268,00€RNase L-IN-2
CAS:RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.Fórmula:C16H14N2O2SPureza:98.81%Forma y color:SolidPeso molecular:298.36Ref: TM-T8591
1mg120,00€5mg264,00€10mg395,00€25mg627,00€50mg890,00€100mg1.198,00€200mg1.603,00€1mL*10mM (DMSO)243,00€Nemorubicin
CAS:Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.
Fórmula:C32H37NO13Pureza:97.4%Forma y color:SolidPeso molecular:643.64Eriodictyol
CAS:Eriodictyol: anti-inflammatory, antioxidant, may improve diabetes and atopic dermatitis symptoms.Fórmula:C15H12O6Pureza:98.03% - 99.32%Forma y color:SolidPeso molecular:288.253-Deazauridine
CAS:3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.Fórmula:C10H13NO6Pureza:99.86%Forma y color:SolidPeso molecular:243.21T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFórmula:C29H27NO8Pureza:97.88% - 99.29%Forma y color:SolidPeso molecular:517.53Ref: TM-T5416
1mg48,00€5mg96,00€10mg144,00€25mg254,00€50mg424,00€100mg627,00€200mg998,00€1mL*10mM (DMSO)107,00€AI-10-49
CAS:AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Fórmula:C30H22F6N6O5Pureza:97.14%Forma y color:SolidPeso molecular:660.52Ref: TM-T6753
2mg38,00€5mg57,00€10mg92,00€25mg160,00€50mg231,00€100mg343,00€200mg485,00€1mL*10mM (DMSO)84,00€Brr2-IN-3
CAS:Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.Fórmula:C24H20N4O3SPureza:99.26%Forma y color:SolidPeso molecular:444.51Ref: TM-T22282
1mg52,00€2mg65,00€5mg92,00€10mg161,00€25mg290,00€50mg420,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)110,00€Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.
Fórmula:C10H14N2Na3O14P3Pureza:99.78%Forma y color:White Amorphous PowderPeso molecular:548.115-BrdU
CAS:5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!Fórmula:C9H11BrN2O5Pureza:99.54% - 99.87%Forma y color:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:307.1Phosphonoformic acid trisodium salt hexa
CAS:Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.Fórmula:CH12Na3O11PPureza:98%Forma y color:SolidPeso molecular:300.03Tipiracil
CAS:Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.Fórmula:C9H11ClN4O2Pureza:99.815%Forma y color:SolidPeso molecular:242.661,4-Anthraquinone
CAS:1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.Fórmula:C14H8O2Pureza:95.96% - 97.01%Forma y color:Orange Brown SolidPeso molecular:208.21TH588 hydrochloride
CAS:TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.Fórmula:C13H13Cl3N4Forma y color:SolidPeso molecular:331.63SCR7 pyrazine
CAS:SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Fórmula:C18H12N4OSPureza:98.72% - 99.85%Forma y color:SolidPeso molecular:332.38Ref: TM-T1724
1mg39,00€2mg50,00€5mg79,00€10mg120,00€25mg258,00€50mg408,00€100mg588,00€1mL*10mM (DMSO)79,00€Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Fórmula:C5H7N6NaO5SPureza:99.55%Forma y color:SolidPeso molecular:286.2CX-5461 dihydrochloride
CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).Fórmula:C27H29Cl2N7O2SForma y color:SolidPeso molecular:586.54Simeprevir
CAS:Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Fórmula:C38H47N5O7S2Pureza:99.45% - 99.92%Forma y color:SolidPeso molecular:749.94
