Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 793 productos de "Síntesis de ADN / ARN"
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PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Fórmula:C21H16ClN5O3SPureza:99.19%Forma y color:SolidPeso molecular:453.9Ref: TM-T84770
1mg92,00€5mg188,00€10mg313,00€25mg603,00€50mg840,00€100mg1.169,00€200mg1.586,00€1mL*10mM (DMSO)216,00€DHX9-IN-8
CAS:<p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>Fórmula:C18H16N2O3S2Forma y color:SolidPeso molecular:372.46VVD-214
CAS:VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Fórmula:C20H21F2N3O4SPureza:99.24% - 99.93%Forma y color:SoildPeso molecular:437.46Ref: TM-T85309
1mg72,00€5mg156,00€10mg235,00€25mg378,00€50mg540,00€100mg747,00€1mL*10mM (DMSO)167,00€Metribuzin
CAS:<p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>Fórmula:C8H14N4OSPureza:99.07%Forma y color:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Peso molecular:214.29GSK4418959
CAS:GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.Fórmula:C31H30F4N4O5SPureza:99.141%Forma y color:SoildPeso molecular:646.65Locked nucleic acid 1
CAS:Locked nucleic acid 1 is an LNA-type nucleoside derivative.Fórmula:C32H32N2O8Pureza:98%Forma y color:SolidPeso molecular:572.61RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Fórmula:C19H17N3Forma y color:SolidPeso molecular:287.362'-Azido-2'-deoxyuridine
CAS:2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.Fórmula:C9H11N5O5Pureza:98%Forma y color:SolidPeso molecular:269.21E-982
CAS:E-982 is derived from the reference compound.Fórmula:C25H31NO6SPureza:98%Forma y color:SolidPeso molecular:473.58Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Fórmula:C16H17BrClN3O3Pureza:99.53%Forma y color:Off-White SolidPeso molecular:414.68Ref: TM-T6856
1mg37,00€5mg87,00€10mg123,00€25mg240,00€50mg363,00€100mg547,00€500mg1.198,00€1mL*10mM (DMSO)A consultarE3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Fórmula:C21H30O6Pureza:99.52%Forma y color:SolidPeso molecular:378.463,4-Dihydroxybenzylamine hydrobromide
CAS:<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Fórmula:C7H10BrNO2Pureza:98.49%Forma y color:Light Beige Crystalline PowderPeso molecular:220.06CGP 53353
CAS:CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Fórmula:C20H13F2N3O2Pureza:98.11%Forma y color:SolidPeso molecular:365.33Phelorphan
CAS:Phelorphan is an inhibitor of enkephalinase.Fórmula:C20H22N2O4SPureza:98%Forma y color:SolidPeso molecular:386.46Homocarbonyltopsentin
CAS:Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.Fórmula:C21H14N4O3Pureza:98%Forma y color:SolidPeso molecular:370.36ML372
CAS:ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.Fórmula:C18H20N2O4SForma y color:SolidPeso molecular:360.43DDD100097
CAS:DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.Fórmula:C22H30Cl2F2N4O2SPureza:98.89%Forma y color:SolidPeso molecular:523.47HBV-IN-14
CAS:HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).Fórmula:C22H21ClN2O5Forma y color:SolidPeso molecular:428.87CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Fórmula:C16H18N2O7SPureza:99.95%Forma y color:SolidPeso molecular:382.392-Keto-D-galactose
CAS:2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.Fórmula:C6H10O6Pureza:98%Forma y color:SolidPeso molecular:178.14
