Proteasa del VIH
Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.
Se han encontrado 450 productos de "Proteasa del VIH"
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Raltegravir potassium
CAS:<p>Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.</p>Fórmula:C20H20FN6O5·KPureza:98% - 99.55%Forma y color:Off-White SolidPeso molecular:482.51Des(benzylpyridyl) Atazanavi
CAS:<p>The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.</p>Fórmula:C26H43N5O7Pureza:98% - 99.75%Forma y color:SolidPeso molecular:537.65PMEDAP
CAS:<p>PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency</p>Fórmula:C8H13N6O4PPureza:99.77%Forma y color:SolidPeso molecular:288.2Obefazimod
CAS:<p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>Fórmula:C16H10ClF3N2OPureza:99.86%Forma y color:SolidPeso molecular:338.71Raltegravir
CAS:<p>Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV</p>Fórmula:C20H21FN6O5Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:444.42Dolutegravir
CAS:<p>Dolutegravir (GSK1349572), HIV integrase inhibitor with IC50 of 2.7 nM, partly effective against some raltegravir-resistant HIV strains.</p>Fórmula:C20H19F2N3O5Pureza:98.97% - 99.75%Forma y color:White To Pale Yellow SolidPeso molecular:419.38RN-18
CAS:<p>RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).</p>Fórmula:C20H16N2O4SPureza:97.21% - 98.39%Forma y color:SolidPeso molecular:380.42Filgotinib
CAS:<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Fórmula:C21H23N5O3SPureza:98.03% - ≥95%Forma y color:SolidPeso molecular:425.5Filgotinib maleate
CAS:<p>Filgotinib maleate, a selective oral JAK1 inhibitor, treats RA and Crohn's. IC50s: JAK1-10nM, JAK2-28nM, JAK3-810nM, TYK2-116nM.</p>Fórmula:C25H27N5O7SForma y color:SolidPeso molecular:541.58Nelfinavir Mesylate
CAS:<p>Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).</p>Fórmula:C33H49N3O7S2Pureza:95.81% - 98.51%Forma y color:A White Or Almost White PowderPeso molecular:663.89HIV-1 Inhibitor 18A
CAS:<p>HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates.</p>Fórmula:C14H11N5O2SPureza:99.79%Forma y color:SolidPeso molecular:313.33HIV-1 Nef-IN-1
CAS:<p>HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).</p>Fórmula:C18H16O2Pureza:99.90%Forma y color:SolidPeso molecular:264.32Etravirine
CAS:<p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Fórmula:C20H15BrN6OPureza:97.61% - 99.74%Forma y color:White To Off-White SolidPeso molecular:435.28Lamivudine 13C,15N2
CAS:<p>Lamivudine 13C,15N2, a BCH-189 impurity, blocks HIV/HBV reverse transcriptase as an NRTI.</p>Fórmula:C8H9N3O4SPureza:98%Forma y color:SolidPeso molecular:246.22Nelfinavir
CAS:<p>Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.</p>Fórmula:C32H45N3O4SPureza:98.16% - 99.5%Forma y color:White To Off-White Crystalline PowderPeso molecular:567.78Suvizumab
CAS:<p>Suvizumab (KD-247) is a neutralizing anti-HIV-1 antibody with IC50 values of 0.1-1.0 µg/mL; it lowers viral load and prevents infection.</p>Forma y color:LiquidElipovimab
CAS:<p>Elipovimab, a potent and broadly neutralizing antibody against HIV-1, targets and eliminates HIV-infected cells [1].</p>Forma y color:LiquidSemzuvolimab
CAS:<p>Semzuvolimab, a murine IgG1κ antibody, targets the p55 T-cell surface antigen T4/Leu-3 (CD4).</p>Forma y color:LiquidBenzalphthalide
CAS:<p>Benzalphthalide (NSC-2824) is a chemical compound with anti-HIV activity.</p>Fórmula:C15H10O2Pureza:99.94%Forma y color:Pale Yellow To Yellow Crystalline PowderPeso molecular:222.24Zinlirvimab
CAS:<p>Zinlirvimab is a humanized IgG1-λ2 monoclonal antibody that neutralizes HIV by targeting the HIV-1 gp120 envelope glycoprotein, specifically the IIIB gp120 V3</p>Forma y color:Liquid
