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Proteasa del VIH

Proteasa del VIH

Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.

Se han encontrado 449 productos de "Proteasa del VIH"

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  • HIV-1 protease-IN-11

    CAS:
    <p>HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacy</p>
    Fórmula:C26H37N3O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:503.65
  • HIV-1 protease-IN-8

    CAS:
    <p>HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.</p>
    Fórmula:C25H35N3O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:489.63
  • HIV-1 protease-IN-7

    CAS:
    <p>HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].</p>
    Fórmula:C68H104N10O12S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1285.68
  • HIV-1 protease-IN-12

    CAS:
    <p>HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-</p>
    Fórmula:C25H35N3O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:489.63
  • HIV-1 protease-IN-9

    CAS:
    <p>HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and a</p>
    Fórmula:C37H41N7O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:679.83
  • NNRTIs-IN-1

    CAS:
    <p>NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-type</p>
    Fórmula:C28H22N6O3
    Forma y color:Solid
    Peso molecular:490.51
  • L 687908

    CAS:
    <p>L 687908 is a potent inhibitor of hydroxyethylene-containing HIV protease.</p>
    Fórmula:C40H51N5O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:681.86
  • HIV-IN-8

    CAS:
    <p>HIV-IN-8 (Compound 9) acts as an HIV inhibitor, suppressing HIV replication with an effective concentration (EC50) of 13 μg/mL [1].</p>
    Fórmula:C36H30O16
    Forma y color:Solid
    Peso molecular:718.61
  • PNU-103017

    CAS:
    <p>PNU-103017 is an inhibitor of HIV protease.</p>
    Fórmula:C28H28N2O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:504.6
  • R 87366

    CAS:
    <p>R 87366 is used as a water-soluble HIV protease inhibitor.</p>
    Fórmula:C32H39N7O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:617.7
  • L 694746

    CAS:
    <p>L 694746 is an inhibitor of HIV-1 protease.</p>
    Fórmula:C35H42N2O8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:618.72
  • Berlopentin

    CAS:
    <p>Berlopentin is splenopentin analog used to treat HIV-positive patients. It also has immunostimulatory properties.</p>
    Fórmula:C35H55N9O11
    Forma y color:Solid
    Peso molecular:777.86
  • DGKα-IN-8

    CAS:
    <p>DGKα-IN-8 (Example 51) is a potent diacylglycerol kinase alpha (DGKα) inhibitor, exhibiting an IC50 of 22.491 nM and an EC50 of 0.256 nM.</p>
    Fórmula:C23H19ClF3N5O
    Forma y color:Solid
    Peso molecular:473.88
  • Ulonivirine

    CAS:
    <p>Ulonivirine is an orally active non-nucleoside reverse transcriptase inhibitor that exhibits high antiviral activity and can be used to study HIV-1 infection.</p>
    Fórmula:C18H8ClF6N5O3
    Forma y color:Solid
    Peso molecular:491.73
  • Teropavimab

    CAS:
    <p>Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].</p>
    Forma y color:Liquid
  • Azt-pmap

    CAS:
    <p>AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].</p>
    Fórmula:C20H25N6O8P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:508.42
  • Ro 31-8588

    CAS:
    <p>Talviraline (HBY 097) inhibits HIV-1 replication and reduces cell death in various cells and immune cells.</p>
    Fórmula:C33H56N4O5
    Forma y color:Solid
    Peso molecular:588.82
  • I-XW-053

    CAS:
    <p>I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-</p>
    Fórmula:C22H16N2O2
    Pureza:99.05%
    Forma y color:Solid
    Peso molecular:340.37
  • Glycolithocholic acid 3-sulfate disodium

    CAS:
    <p>Glycolithocholic acid 3-sulfate (disodium) demonstrates inhibitory effects on in vitro HIV-1 replication and has potential applications in HIV infection and</p>
    Fórmula:C26H41NNa2O7S
    Forma y color:Solid
    Peso molecular:557.65
  • PDDC inhibitor

    CAS:
    <p>PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is an nSMase2 inhibitor.</p>
    Fórmula:C27H29N5O4
    Pureza:96.09% - 99.39%
    Forma y color:Solid
    Peso molecular:487.55