Proteasa del VIH
Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.
Se han encontrado 449 productos de "Proteasa del VIH"
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HIV-1 inhibitor-54
CAS:<p>HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.</p>Fórmula:C27H30N6O4SPureza:98.05% - 99.44%Forma y color:SoildPeso molecular:534.63Lamivudine, (+/-)-trans-
CAS:<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Fórmula:C8H11N3O3SPureza:98%Forma y color:SolidPeso molecular:229.26Methyl piperazine-2-carboxylate
CAS:<p>Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.</p>Fórmula:C6H12N2O2Forma y color:SolidPeso molecular:144.172Desthiazolylmethyl ritonavir
CAS:<p>Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.</p>Fórmula:C33H43N5O4SForma y color:SolidPeso molecular:605.791NBD-14189
CAS:<p>NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).</p>Fórmula:C18H16F4N4O2SForma y color:SolidPeso molecular:428.40HIV-1 protease-IN-6
<p>HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.</p>Fórmula:C27H31FN2O6SForma y color:SolidPeso molecular:530.61BRD-K98645985
CAS:<p>BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.</p>Fórmula:C33H43N5O4Pureza:98%Forma y color:SolidPeso molecular:573.73HIV-1 inhibitor-52
CAS:<p>HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.</p>Fórmula:C46H72FNO5SForma y color:SolidPeso molecular:770.13ZK-316
CAS:<p>ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.</p>Fórmula:C27H22D6N6O3S2Forma y color:SolidPeso molecular:554.72PD 134922
CAS:<p>PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.</p>Fórmula:C37H61N5O7SPureza:98%Forma y color:SolidPeso molecular:719.97MIV-150
CAS:<p>MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).</p>Fórmula:C19H17FN4O3Pureza:98%Forma y color:SolidPeso molecular:368.36BMIM-TFSI
CAS:<p>BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.</p>Fórmula:C10H15F6N3O4S2Forma y color:SolidPeso molecular:419.364A 76889
CAS:<p>A 76889 is an inhibitor of HIV-1 protease.</p>Fórmula:C44H58N8O6Pureza:98%Forma y color:SolidPeso molecular:794.98HIV-1 inhibitor-44
<p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>Fórmula:C23H26N2O4SForma y color:SolidPeso molecular:426.53Gardiquimod hydrochloride
CAS:<p>Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.</p>Fórmula:C17H24ClN5OForma y color:SolidPeso molecular:349.858BRN3OMe
CAS:<p>BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.</p>Fórmula:C7H13N3O4Forma y color:SolidPeso molecular:203.196GSK3739936
CAS:<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Fórmula:C34H43FN2O4Forma y color:SolidPeso molecular:562.71Telinavir
CAS:<p>Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.</p>Fórmula:C33H44N6O5Forma y color:SolidPeso molecular:604.74HIV-1 inhibitor-40
<p>HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.</p>Fórmula:C25H18N6O2Forma y color:SolidPeso molecular:434.45L-697639
CAS:<p>L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.</p>Fórmula:C18H21N3O2Forma y color:SolidPeso molecular:311.38
