Proteasa del VIH
Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.
Se han encontrado 449 productos de "Proteasa del VIH"
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SPD-756
CAS:<p>SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C12H16N6O3Pureza:98%Forma y color:SolidPeso molecular:292.29NNRT-IN-6
<p>NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.</p>Fórmula:C32H31N9O3SForma y color:SolidPeso molecular:621.71Aureothin
CAS:<p>Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).</p>Fórmula:C22H23NO6Forma y color:SolidPeso molecular:397.42HIV-1 inhibitor-80
<p>HIV-1inhibitor-80 (compound M44) is an HIV-1 inhibitor with an EC50 of 5-148 nM. It demonstrates excellent metabolic stability and low cytotoxicity in human plasma and liver microsomes.</p>Fórmula:C26H19N7OForma y color:SolidPeso molecular:445.475Bictegravir Sodium
CAS:<p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>Fórmula:C21H17F3N3NaO5Pureza:99.97%Forma y color:SolidPeso molecular:471.36CI-39
CAS:<p>CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 >30 µM.</p>Fórmula:C19H18N2O4Forma y color:SolidPeso molecular:338.36Indoline
CAS:<p>Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C8H9NForma y color:Clear To Yellow LiquidPeso molecular:119.16(-)-Rabdosiin
CAS:<p>(-)-Rabdosiin, identified as a novel phenolic marker in Symphytum officinale L., exhibits antioxidant, neuroprotective, and anti-HIV activities [1].</p>Fórmula:C36H30O16Forma y color:SolidPeso molecular:718.61HIV-1 protease-IN-14
<p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>Forma y color:Odour SolidHIV-IN-2
CAS:<p>HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].</p>Fórmula:C34H27ClF7N9O3SForma y color:SolidPeso molecular:810.144-Deoxy-4α-phorbol
CAS:<p>4-Deoxy-4α-phorbol, a tetracyclic diterpene identified in E.</p>Fórmula:C20H28O5Forma y color:SolidPeso molecular:348.43JE-2178
CAS:<p>JE-2178 is compound with high bioavailability .</p>Fórmula:C35H51N5O6SForma y color:SolidPeso molecular:669.87Hinnuliquinone
CAS:Hinnuliquinone is an anti-HIV agent.Fórmula:C32H30N2O4Pureza:98%Forma y color:SolidPeso molecular:506.59ICeD-2
<p>ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.</p>Fórmula:C20H29N3OForma y color:SolidPeso molecular:327.46Elvucitabine
CAS:<p>Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.</p>Fórmula:C9H10FN3O3Forma y color:SolidPeso molecular:227.19Clavirolide L
<p>Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without</p>Fórmula:C20H28O3Forma y color:SolidPeso molecular:316.43RPR103611
CAS:<p>RPR103611, a betulinic acid derivative, inhibits HIV-1; IC50s: CCR5 (YU2) 80, CXCR4 (NL4-3) 0.27, dual-tropic (89.6) 0.17.</p>Fórmula:C46H78N2O6Forma y color:SolidPeso molecular:755.12Decanoyl-RVKR-CMK TFA
CAS:<p>Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.</p>Fórmula:C36H67ClF3N11O7Forma y color:SolidPeso molecular:858.45Emtricitabine S-oxide
CAS:<p>Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.</p>Fórmula:C8H10FN3O4SPureza:98%Forma y color:SolidPeso molecular:263.25(+)-Carbovir triphosphate
CAS:<p>(+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.</p>Fórmula:C11H16N5O11P3Forma y color:SolidPeso molecular:487.19TAT peptide
<p>TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.</p>Fórmula:C65H124N34O15Pureza:98%Forma y color:SolidPeso molecular:1621.91HIV-1 protease-IN-4
<p>HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC & 67x C24 compared to atazanavir.</p>Fórmula:C48H69N7O11Forma y color:SolidPeso molecular:920.1JE-2147
CAS:<p>JE-2147: a hybrid peptide with multiple amino acid types linked by peptide bonds.</p>Fórmula:C32H37N3O5SForma y color:SolidPeso molecular:575.72GLR-19
CAS:<p>GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].</p>Fórmula:C102H194N40O20Pureza:98%Forma y color:SolidPeso molecular:2300.89HIV-1 protease-IN-10
<p>HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) and</p>Fórmula:C23H40O5Pureza:98%Forma y color:SolidPeso molecular:396.56Alvircept sudotox
CAS:<p>Alvircept sudotox, a recombinant CD4 fused with exotoxin A from Pneumonas aeruginosa, is utilized in HIV infection research [1].</p>Forma y color:LiquidCarbovir triphosphate
CAS:<p>Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].</p>Fórmula:C11H16N5O11P3Forma y color:SolidPeso molecular:487.19Kni 102
CAS:<p>Kni 102 is a biochemical.</p>Fórmula:C31H41N5O7Forma y color:SolidPeso molecular:595.69Lopinavir Metabolite M-1
CAS:<p>Lopinavir Metabolite M-1, derived from Lopinavir, inhibits HIV protease (Ki=0.7 pM) and shows antiviral activity in vitro.</p>Fórmula:C37H46N4O6Forma y color:SolidPeso molecular:642.78Scirpusin A
CAS:<p>Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.</p>Fórmula:C28H22O7Forma y color:SolidPeso molecular:470.47NF279
CAS:<p>P2X1 antagonist</p>Fórmula:C49H36N6Na6O23S6Pureza:98%Forma y color:SolidPeso molecular:1407.17HIV-1 inhibitor-59
<p>HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.</p>Fórmula:C28H28FN5O3SForma y color:SolidPeso molecular:533.62QYL-685
CAS:<p>QYL-685 is a methylenecyclopropane nucleoside analog.</p>Fórmula:C20H24N7O5PForma y color:SolidPeso molecular:473.42Delavirdine
CAS:<p>Delavirdine, an NNRTI for HIV-1, is used in HAART.</p>Fórmula:C22H28N6O3SForma y color:SolidPeso molecular:456.56Hypoglaunine D
CAS:<p>Hypoglaunine D, an anti-HIV analogue of Triptonine B, inhibits HIV in H9 cells with an EC50 of 22 μg/ml.</p>Fórmula:C41H47NO19Forma y color:SolidPeso molecular:857.81HIV-IN-9
<p>HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.</p>Forma y color:Odour SolidKadsuralignan A
CAS:<p>Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an</p>Fórmula:C22H26O7Forma y color:SolidPeso molecular:402.44MB-66
<p>MB-66 (MAPP-66) is a fully human IgG1 antibody targeting HSV and HIV. It is a monoclonal antibody membrane intended for vaginal application. The isotype control for MB-66 can be referred to as HumanIgG1kappa, Isotype Control.</p>Forma y color:Odour LiquidCys-TAT(47-57)
CAS:<p>Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.</p>Fórmula:C67H124N34O14SPureza:98%Forma y color:SolidPeso molecular:1661.99HIV-1 inhibitor-58
<p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>Fórmula:C26H24N6O2Forma y color:SolidPeso molecular:452.5112-Oxocalanolide A
<p>12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.</p>Fórmula:C22H24O5Forma y color:SolidPeso molecular:368.429Salvianan A
CAS:<p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>Fórmula:C20H17NO2Forma y color:SolidPeso molecular:303.35Amdoxovir
CAS:<p>Amdoxovir is a reverse transcriptase inhibitor.</p>Fórmula:C9H12N6O3Forma y color:SolidPeso molecular:252.23HIV gag peptide (197-205)
CAS:<p>HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI</p>Fórmula:C45H81N11O14S2Pureza:98%Forma y color:SolidPeso molecular:1064.32MPG, HIV related
CAS:<p>MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.</p>Fórmula:C126H201N35O33SPureza:98%Forma y color:SolidPeso molecular:2766.22Kuguacin N
<p>Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.</p>Fórmula:C30H46O4Forma y color:SolidPeso molecular:470.694Peptide T TFA
CAS:<p>Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.</p>Fórmula:C37H56F3N9O18Pureza:98%Forma y color:SolidPeso molecular:971.89Peptide T
CAS:<p>Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.</p>Fórmula:C35H55N9O16Pureza:98%Forma y color:SolidPeso molecular:857.86HIV-1 inhibitor-81
<p>HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.</p>Fórmula:C32H44N2O8SForma y color:SolidPeso molecular:616.77Globotriaosylceramides (porcine)
CAS:<p>Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.</p>Fórmula:C60H113NO18Forma y color:SolidPeso molecular:1136.553
