Proteasa del VIH
Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.
Se han encontrado 449 productos de "Proteasa del VIH"
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HIV p17 Gag (77-85)
CAS:<p>Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.</p>Fórmula:C44H72N10O15Pureza:98%Forma y color:SolidPeso molecular:981.1Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
CAS:<p>Tenofovir-C3-O-C12 has a longer half-life, potent anti-HIV effects, and better pharmacokinetics than tenofovir.</p>Fórmula:C29H55N6O5PSiForma y color:SolidPeso molecular:626.855SPD-756
CAS:<p>SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C12H16N6O3Pureza:98%Forma y color:SolidPeso molecular:292.29Scirpusin A
CAS:<p>Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.</p>Fórmula:C28H22O7Forma y color:SolidPeso molecular:470.47HIV-1 inhibitor-58
<p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>Fórmula:C26H24N6O2Forma y color:SolidPeso molecular:452.51Salvianan A
CAS:<p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>Fórmula:C20H17NO2Forma y color:SolidPeso molecular:303.35BMS-955176 TFA
CAS:<p>GSK3532795: Oral HIV-1 maturation inhibitor, broad virus coverage, EC50: 15 nM, good preclinical pharmacokinetics.</p>Fórmula:C44H64N2O8SPureza:98%Forma y color:SolidPeso molecular:781.06Kadsuralignan A
CAS:<p>Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an</p>Fórmula:C22H26O7Forma y color:SolidPeso molecular:402.44HIV-IN-2
CAS:<p>HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].</p>Fórmula:C34H27ClF7N9O3SForma y color:SolidPeso molecular:810.14Clavirolide L
<p>Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without</p>Fórmula:C20H28O3Forma y color:SolidPeso molecular:316.43Bictegravir Sodium
CAS:<p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>Fórmula:C21H17F3N3NaO5Pureza:99.97%Forma y color:SolidPeso molecular:471.36(2S,5S)-Censavudine
<p>(2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.</p>Fórmula:C12H12N2O4Forma y color:SolidPeso molecular:248.23UK-88947 HCl
CAS:<p>UK 88947 is a protease inhibitor.</p>Fórmula:C41H63ClN6O6Pureza:98%Forma y color:SolidPeso molecular:771.44MPG, HIV related
CAS:<p>MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.</p>Fórmula:C126H201N35O33SPureza:98%Forma y color:SolidPeso molecular:2766.22Elvucitabine
CAS:<p>Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.</p>Fórmula:C9H10FN3O3Forma y color:SolidPeso molecular:227.19BNM-III-170
CAS:<p>BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.</p>Fórmula:C25H26ClF7N6O6Forma y color:SolidPeso molecular:674.96N36Mut(e,g)
<p>N36Mut(e,g) is an HIV fusion peptide inhibitor targeting gp41. It functions by disrupting the formation of the homotrimeric coiled coil of the N-terminal helix in the pre-hairpin intermediate, leading to the creation of a heterotrimer.</p>Fórmula:C189H317N55O56Forma y color:SolidPeso molecular:4255.87PROTAC Vif degrader-1
<p>PROTACVif degrader-1 (Compound L15) is a Vif-targeted PROTAC degrader exhibiting anti-HIV-1 virucidal activity, with an EC50 of 33.35 μM against HIV-1IIIB.</p>Forma y color:Odour SolidHIV-1 protease-IN-14
<p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>Forma y color:Odour SolidIndoline
CAS:<p>Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C8H9NForma y color:Clear To Yellow LiquidPeso molecular:119.16Pol (476-484), HIV-1 RT Epitope
CAS:<p>Pol (476-484), HIV-1 RT Epitope is a biologically active peptide and represents the dominant HLA A*0201-restricted epitope within HIV-1 reverse transcriptase (</p>Fórmula:C46H78N12O12Forma y color:SolidPeso molecular:991.18[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92)
CAS:[(Cys(Bzl)84, Glu(OBzl)85)]CD4 (81-92) is a selective HIV-1 inhibitor that blocks the interaction between HIV-1 and CD4 molecules, thereby inhibiting viral infection and cell fusion. At a concentration of 25 μM, it can completely prevent fusion formation [1].Fórmula:C76H108N14O26SForma y color:SolidPeso molecular:1665.81NF279
CAS:<p>P2X1 antagonist</p>Fórmula:C49H36N6Na6O23S6Pureza:98%Forma y color:SolidPeso molecular:1407.17VIR-165
<p>VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.</p>Fórmula:C109H158N22O25S2Pureza:98%Forma y color:SolidPeso molecular:2240.7GP120, HIV-1 MN
GP120, HIV-1 MN, a peptide, is utilized in researching HIV infection [1] [2].Fórmula:C135H221N45O33Forma y color:SolidPeso molecular:3002.5Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2
CAS:<p>Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2, a peptide substrate for HIV-1 protease, is used in inhibition assays.</p>Fórmula:C38H58N10O12Forma y color:SolidPeso molecular:846.93Peptide T
CAS:<p>Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.</p>Fórmula:C35H55N9O16Pureza:98%Forma y color:SolidPeso molecular:857.86Interiorin
CAS:<p>Interiorin, extracted from Kadsura heteroclita, exhibits moderate anti-HIV activity, exhibiting an EC_50 of 1.6 μg/mL [1].</p>Fórmula:C27H30O8Forma y color:SolidPeso molecular:482.52Amdoxovir
CAS:<p>Amdoxovir is a reverse transcriptase inhibitor.</p>Fórmula:C9H12N6O3Forma y color:SolidPeso molecular:252.23HIV-1 inhibitor-75
<p>HIV-1inhibitor-75 is a human immunodeficiency virus 1 (HIV-1) inhibitor with an EC50 range of 0.0039-0.338 μM. Its target is the reverse transcriptase, exhibiting an IC50 value of 0.055 μM. Additionally, HIV-1inhibitor-75 demonstrates good metabolic stability in vitro, presenting moderate clearance rates and an extended half-life in human plasma and liver microsomes.</p>Fórmula:C25H20ClN3O3SForma y color:SolidPeso molecular:477.96Globotriaosylceramides (porcine)
CAS:<p>Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.</p>Fórmula:C60H113NO18Forma y color:SolidPeso molecular:1136.553Enfuvirtide
CAS:<p>Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.</p>Fórmula:C204H301N51O64Pureza:98%Forma y color:White To Off-White Amorphous SolidPeso molecular:4491.9454-Acetylbutyric acid
CAS:<p>4-Acetylbutyric acid is a ketone acid widely used in biochemical experiments and drug synthesis research.</p>Fórmula:C6H10O3Pureza:99.88%Forma y color:SolidPeso molecular:130.14CI-39
CAS:<p>CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 >30 µM.</p>Fórmula:C19H18N2O4Forma y color:SolidPeso molecular:338.36NNRTIs-IN-3
<p>NNRTIs-IN-3 (compound 8) is an HIV-1 non-nucleoside reverse transcriptase inhibitor, displaying potent efficacy with an EC50 value of 0.01 µM [1].</p>Fórmula:C17H20ClN5OPureza:98%Forma y color:SolidPeso molecular:345.83Aureothin
CAS:<p>Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).</p>Fórmula:C22H23NO6Forma y color:SolidPeso molecular:397.42(±)-BI-D
CAS:<p>(±)-BI-D is an effective ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site (IC50: 2.4–2.9 μM).</p>Fórmula:C25H27NO4Forma y color:SolidPeso molecular:405.49Saquinavir mesylate
CAS:<p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>Fórmula:C39H54N6O8SPureza:99.19%Forma y color:White Or Pale Yellow PowderPeso molecular:766.9Dideoxyadenosine
CAS:<p>2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].</p>Fórmula:C10H13N5O2Pureza:99.28%Forma y color:Physical Description Off-White Powder (Ntp 1992)Peso molecular:235.242'-Deoxy-2'-fluoroarabinoadenosine
CAS:<p>2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases.</p>Fórmula:C10H12FN5O3Pureza:99.95%Forma y color:SolidPeso molecular:269.23Pseudothymidine
CAS:<p>Pseudothymidine is a C-nucleoside analog of thymidine.</p>Fórmula:C10H14N2O5Pureza:98%Forma y color:SolidPeso molecular:242.23Pentosan Polysulfate Sodium (W/W 43%)
CAS:<p>Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.</p>Pureza:98%Forma y color:SolidPeso molecular:N/A(Z)-9-Propenyladenine
CAS:<p>(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.</p>Fórmula:C8H9N5Forma y color:SolidPeso molecular:175.19TAT (48-57)
CAS:<p>TAT (48-57) is a cell-permeable HIV-1 Tat protein fragment, amino acids 48-57.</p>Fórmula:C55H109N31O12Pureza:98%Forma y color:SolidPeso molecular:1396.65Abacavir hydroxyacetate
CAS:<p>Abacavir hydroxyacetate is a nucleoside analog reverse transcriptase inhibitor used in the study of HIV infection.</p>Fórmula:C16H20N6O3Pureza:98.29%Forma y color:SolidPeso molecular:344.37gardiquimod TFA salt
CAS:<p>Gardiquimod diTFA is a TLR7/8 agonist that may block HIV-1 in macrophages and PBMCs, active under 10 μM.</p>Fórmula:C21H25F6N5O5Forma y color:SolidPeso molecular:541.44Tenofovir hydrate
CAS:<p>Tenofovir hydrate (GS 1278 hydrate) is a nucleotide reverse transcriptase inhibitor with antiviral activity.</p>Fórmula:C9H16N5O5PPureza:99.63%Forma y color:SolidPeso molecular:305.23Letrazuril
CAS:<p>Letrazuril is a compound of the anti-HIV.</p>Fórmula:C17H9Cl2FN4O2Forma y color:SolidPeso molecular:391.18Etravirine D4
CAS:<p>Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.</p>Fórmula:C20H15BrN6OPureza:98%Forma y color:SolidPeso molecular:439.3Cabotegravir sodium
CAS:<p>Cabotegravir sodium inhibits HIV integrase (IC50: 2.5 nM), metabolized by UGT1A1, with minimal ARV interaction.</p>Fórmula:C19H16F2N3NaO5Forma y color:SolidPeso molecular:427.34
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