Proteasa del VIH
Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.
Se han encontrado 450 productos de "Proteasa del VIH"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
DPC-681
CAS:<p>DPC-681 is a potent and selective HIV protease inhibitor (IC90s: 4 to 40 nM for wild-type HIV-1).</p>Fórmula:C35H48FN5O5SForma y color:SolidPeso molecular:669.85HIV-1 inhibitor-19
CAS:<p>HIV-1 inhibitor-19 is a potent NNRTI targeting L100I, K103N, V106A/F227L mutants; EC50s: 7.3, 9.2, 21.0 nM respectively.</p>Fórmula:C24H22BClN2O5SForma y color:SolidPeso molecular:496.77HIV-1 inhibitor-15
CAS:<p>HIV-1 inhibitor-15 (compound 9d): Potent, broad-spectrum, EC50=1.7-9 nM for various strains, good solubility/safety, oral use.</p>Fórmula:C24H20N6Forma y color:SolidPeso molecular:392.46TX-1918
CAS:<p>TX-1918, a tyrphostin, blocks eEF-2K to hinder HepG2, HCT116 cell growth.</p>Fórmula:C14H12O3Forma y color:SolidPeso molecular:228.24S 2720
CAS:<p>S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline.</p>Fórmula:C14H15ClN2O2SForma y color:SolidPeso molecular:310.81E7-03
CAS:<p>1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).</p>Fórmula:C28H29N3O6Forma y color:SolidPeso molecular:503.55DPC-961
CAS:<p>DPC-961, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C14H10ClF3N2OForma y color:SolidPeso molecular:314.69B07 hydrochloride
CAS:B07 hydrochloride is a CCR5 antagonist-based inhibitor of HIV-1 entry.Fórmula:C29H38ClFN4O2Pureza:98%Forma y color:SolidPeso molecular:529.09HIV-1 inhibitor-20
CAS:<p>HIV-1 inhibitor-20 is a potent HIV-1 inhibitor.</p>Fórmula:C19H11ClF3N3O2Forma y color:SolidPeso molecular:405.76BMS-585248
CAS:<p>BMS-585248 is a highly effective HIV-1 adhesion inhibitor that targets the viral envelope protein gp120.</p>Fórmula:C22H18FN7O3Forma y color:SolidPeso molecular:447.42AIC-292
CAS:<p>AIC-292 is a potent, tolerable reverse transcriptase inhibitor active against various HIV-1 strains, including NNRTI-resistant K103N, G190A, Y181C.</p>Fórmula:C19H12Cl2F2N4O2Forma y color:SolidPeso molecular:437.23L 739594
CAS:<p>L 739594 is an inhibitor of HIV-1 protease.</p>Fórmula:C31H47N3O6Pureza:98%Forma y color:SolidPeso molecular:557.72HIV-1 inhibitor-28
CAS:<p>HIV-1 inhibitor-28: potent, selective, EC50=58 nM, low MT-4 cell toxicity (CC50=38.6 μM), valuable in AIDS research.</p>Fórmula:C26H32N6O3SForma y color:SolidPeso molecular:508.64HIV-1 inhibitor-45
CAS:<p>HIV-1 inhibitor-45 is a potent inhibitor of HIV-1 RNase H (IC50: 0.067 μM) and has antiviral effects.</p>Fórmula:C23H24N4O8SForma y color:SolidPeso molecular:516.52HIV-1 inhibitor-21
CAS:<p>HIV-1 inhibitor-21 (compound 9b) blocks HIV-1 RT effectively (IC50: 0.55 μM), targeting wild-type and K103N strains, with low toxicity (CC50: 10.2 μM).</p>Fórmula:C28H24N6O2Forma y color:SolidPeso molecular:476.53HI-236
CAS:<p>HI-236 is used as a non-nucleoside HIV-1 reverse-transcriptase inhibitor.</p>Fórmula:C16H18BrN3O2SPureza:98%Forma y color:SolidPeso molecular:396.3Adenallene
CAS:<p>Adenallene inhibits replication and cytopathic effects of HIV in vitro.</p>Fórmula:C9H9N5OPureza:98%Forma y color:SolidPeso molecular:203.2AQ 148
CAS:<p>AQ 148 is a potent competitive inhibitor of HIV-1 PR.</p>Fórmula:C30H37N3O4Forma y color:SolidPeso molecular:503.63HIV-1 integrase inhibitor 9
CAS:<p>HIV-1 integrase inhibitor 9 (compound 8a) is a potent inhibitor of HIV-1 RNase H (IC50: 12.3 μM) and has antiviral effects.</p>Fórmula:C18H12N2O10Forma y color:SolidPeso molecular:416.3Reverse transcriptase-IN-4
<p>Reverse transcriptase-IN-4: potent, selective NNRT inhibitor; EC50 = 0.053 μM for HIV-1, 0.26 μM for E138K mutant.</p>Fórmula:C17H21N5OSForma y color:SolidPeso molecular:343.45Rovafovir Etalafenamide
CAS:<p>Rovafovir Etalafenamide is a prodrug of anti-HIV nucleoside phosphonate.</p>Fórmula:C21H24FN6O6PPureza:98%Forma y color:SolidPeso molecular:506.42SARS-CoV-IN-2
CAS:<p>SARS-CoV-IN-2 is an effective SARS-CoV replication inhibitor</p>Fórmula:C24H26ClFeN3OPureza:98%Forma y color:SolidPeso molecular:463.78HIV-1 inhibitor-23
CAS:<p>HIV-1 inhibitor-23 suppresses HIV reverse transcriptase, effective on wild-type (EC50: 24.9 nM) and K103N mutant (EC50: 10.4 nM), with in vitro stability.</p>Fórmula:C30H26N6O4SForma y color:SolidPeso molecular:566.63R 82150
CAS:<p>R 82150 is an antiviral and a member of the tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepin-2(1H)-thione family.</p>Fórmula:C16H21N3SPureza:98%Forma y color:SolidPeso molecular:287.42DLC27-14
CAS:<p>DLC27-14 is an HIV-1 Nef specific protein disorder catalyzer.</p>Fórmula:C25H25NO4Forma y color:SolidPeso molecular:403.47HIV-1 inhibitor-32
CAS:<p>HIV-1 inhibitor-32 is a potent inhibitor of HIV-1 that acts on wild-type HIV (IC50: 34 nM) and can be used in AIDS research.</p>Fórmula:C26H29N5O3SForma y color:SolidPeso molecular:491.61HIV-1 protease-IN-2
CAS:<p>HIV-1 protease-IN-2: strong HIV-1 protease blocker, IC50 2.53 nM, fights DRV-sensitive/resistant HIV-1.</p>Fórmula:C27H34N4O7SForma y color:SolidPeso molecular:558.65HIV-1 inhibitor-46
CAS:<p>HIV-1 inhibitor-46, compound 13d, is a potent non-nucleoside reverse transcriptase inhibitor with an EC50 of 1.425 μM, useful in AIDS research.</p>Fórmula:C24H21ClN4OSForma y color:SolidPeso molecular:448.97HIV-1 inhibitor-37
CAS:<p>HIV-1 inhibitor-37, a potent HIV-1 suppressant, shows promise as a novel latent reactivator.</p>Fórmula:C14H11Cl3N4OForma y color:SolidPeso molecular:357.62Tenofovir maleate
CAS:<p>Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used in the treatment of HIV and chronic Hepatitis B.</p>Fórmula:C13H18N5O8PForma y color:SolidPeso molecular:403.28Stampidine
CAS:<p>Stampidine prevents HIV-1, effective against resistant strains at subnanomolar levels.</p>Fórmula:C20H23BrN3O8PPureza:98%Forma y color:SolidPeso molecular:544.29HIV-1 inhibitor-30
CAS:<p>HIV-1 inhibitor-30 (10i) targets RT enzyme, EC50=40nM, IC50=80nM. Effective against seven NNRTI-resistant HIV-1 strains.</p>Fórmula:C19H20ClN3O2Forma y color:SolidPeso molecular:357.83Edelfosine
CAS:<p>inhibits phosphatidylinositol phospholipase C</p>Fórmula:C27H58NO6PPureza:98%Forma y color:SolidPeso molecular:523.73(+)-Dihydrocalanolide A
CAS:<p>DHCal A (NSC 678323) is an oral nonnucleoside Reverse Transcriptase inhibitor for HIV research.</p>Fórmula:C22H28O5Forma y color:SolidPeso molecular:372.45HIV-IN-5
CAS:<p>HIV-IN-5 (5r) inhibits HIV-1 with 0.16 μM IC50, targeting NNIBP as a NNRTI.</p>Fórmula:C30H24N2O8SForma y color:SolidPeso molecular:572.59HIV-1 inhibitor-47
CAS:<p>HIV-1 Inhibitor-47 blocks Vif-APOBEC3G interaction, has 14.33 μM IC50, and may yield antianxiety and antipsychotic derivatives.</p>Fórmula:C12H14N6Forma y color:SolidPeso molecular:242.28L 870810
CAS:<p>L 870810 is a small-molecule inhibitor of HIV-1 integrase with potent antiviral activity in cell culture and good pharmacokinetic properties.</p>Fórmula:C20H19FN4O4SForma y color:SolidPeso molecular:430.45HIV-1 protease-IN-5
CAS:<p>HIV-1 protease-IN-5 is an HIV-1 protease inhibitor (IC50: 1.64 nM). HIV-1 protease-IN-5 exhibits significant effects on wild-type and DRV-resistant HIV-1.</p>Fórmula:C27H29F3N2O7SForma y color:SolidPeso molecular:582.59DPC-963
CAS:<p>DPC-963 is a RNA-directed DNA polymerase inhibitor.</p>Fórmula:C14H9F5N2OForma y color:SolidPeso molecular:316.23Brecanavir
CAS:<p>Brecanavir is a tyrosyl-based arylsulfonamide, high affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type 1.</p>Fórmula:C33H41N3O10S2Forma y color:SolidPeso molecular:703.82ZINC04177596
CAS:<p>ZINC04177596 is a novel Nef Protein Inhibitor with anti-HIV activity.</p>Fórmula:C22H16N6O4Forma y color:SolidPeso molecular:428.4HIV-1 inhibitor-42
CAS:<p>HIV-1 inhibitor-42 (5b) strongly blocks HIV-1 (IC50: 0.06μM) and its RT RNA/DNA polymerases (IC50: 0.518/0.072μM).</p>Fórmula:C22H20N2O5SForma y color:SolidPeso molecular:424.47EP39
<p>EP39 is a potent HIV-1 inhibitor, stabilizing the SP1 domain's helix and blocking virus maturation.</p>Fórmula:C38H62N2O5Forma y color:SolidPeso molecular:626.91SJ-3366
CAS:<p>SJ3366 is a unique and highly potent nonnucleoside reverse transcriptase human immunodeficiency virus type 1 and HIV-2 inhibitor.</p>Fórmula:C21H24N2O3Forma y color:SolidPeso molecular:352.43HIV-1 protease-IN-1
CAS:<p>HIV-1 protease-IN-1, potent HIV inhibitor; IC50=90pM, fights B/C-HIV strains with EC50=89-13.59/8.23nM.</p>Fórmula:C25H35N3O6SForma y color:SolidPeso molecular:505.63VEC-5
CAS:<p>VEC-5: an HIV-1 inhibitor, outperforms RN18 by better binding with Vif in studies.</p>Fórmula:C29H21NO4Pureza:98%Forma y color:SolidPeso molecular:447.48HIV-1 inhibitor-38
CAS:<p>HIV-1 inhibitor-38, or Compound 91, shows promise as a strong latency reversing agent against HIV-1.</p>Fórmula:C15H13Cl3N6Forma y color:SolidPeso molecular:383.66A3N19
CAS:<p>A3N19 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase and is able to act on HIV-1 IIIB (EC50: 3.28 nM).</p>Fórmula:C31H31N9O2SForma y color:SolidPeso molecular:593.7DMJ-I-228
CAS:<p>DMJ-I-228 is a specific inhibitor of HIV-1 entry through interaction with the Env spike by virtue of the incorporation of a guandinium group.</p>Fórmula:C19H19ClFN5O4Forma y color:SolidPeso molecular:435.84gp120-IN-2
CAS:<p>gp120-IN-2 is a potent HIV-1 inhibitor (IC50 = 7.5 μM) with low cytotoxicity (CC50 = 112.93 μM).</p>Fórmula:C15H18N2O5Forma y color:SolidPeso molecular:306.31
