Proteasa del VIH
Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.
Se han encontrado 451 productos de "Proteasa del VIH"
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(2S,5S)-Censavudine
<p>(2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.</p>Fórmula:C12H12N2O4Forma y color:SolidPeso molecular:248.23MB-66
MB-66 (MAPP-66) is a fully human IgG1 antibody targeting HSV and HIV. It is a monoclonal antibody membrane intended for vaginal application. The isotype control for MB-66 can be referred to as HumanIgG1kappa, Isotype Control.Forma y color:Odour LiquidTAT peptide
<p>TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.</p>Fórmula:C65H124N34O15Pureza:98%Forma y color:SolidPeso molecular:1621.91Cys-TAT(47-57)
CAS:Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Fórmula:C67H124N34O14SPureza:98%Forma y color:SolidPeso molecular:1661.9912-Oxocalanolide A
<p>12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.</p>Fórmula:C22H24O5Forma y color:SolidPeso molecular:368.429HIV-1 protease-IN-10
<p>HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) and</p>Fórmula:C23H40O5Pureza:98%Forma y color:SolidPeso molecular:396.56Kuguacin N
<p>Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.</p>Fórmula:C30H46O4Forma y color:SolidPeso molecular:470.694Peptide T TFA
CAS:<p>Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.</p>Fórmula:C37H56F3N9O18Pureza:98%Forma y color:SolidPeso molecular:971.89HIV-1 inhibitor-6
CAS:<p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>Fórmula:C14H10N4O4SPureza:99.33%Forma y color:SolidPeso molecular:330.32HIV p17 Gag (77-85)
CAS:<p>Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.</p>Fórmula:C44H72N10O15Pureza:98%Forma y color:SolidPeso molecular:981.1SPD-756
CAS:<p>SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C12H16N6O3Pureza:98%Forma y color:SolidPeso molecular:292.29NNRT-IN-6
<p>NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.</p>Fórmula:C32H31N9O3SForma y color:SolidPeso molecular:621.71ICeD-2
<p>ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.</p>Fórmula:C20H29N3OForma y color:SolidPeso molecular:327.46HIV-1 inhibitor-58
<p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>Fórmula:C26H24N6O2Forma y color:SolidPeso molecular:452.51Bictegravir Sodium
CAS:<p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>Fórmula:C21H17F3N3NaO5Pureza:99.97%Forma y color:SolidPeso molecular:471.36CI-39
CAS:<p>CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 >30 µM.</p>Fórmula:C19H18N2O4Forma y color:SolidPeso molecular:338.36Indoline
CAS:<p>Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C8H9NForma y color:Clear To Yellow LiquidPeso molecular:119.16Tenofovir-C3-O-C15-CF3 ammonium
CAS:<p>Tenofovir-C3-O-C15-CF3 (ammonium) has a longer half-life and stronger anti-HIV action, improving pharmacokinetics in vivo.</p>Fórmula:C28H52F3N6O5PForma y color:SolidPeso molecular:640.73HIV-1 protease-IN-14
<p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>Forma y color:Odour SolidCarbovir triphosphate
CAS:<p>Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].</p>Fórmula:C11H16N5O11P3Forma y color:SolidPeso molecular:487.19
