Proteasa del VIH
Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.
Se han encontrado 486 productos para "Proteasa del VIH".
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HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Forma y color:Odour SolidHIV-1 inhibitor-81
HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.Fórmula:C32H44N2O8SForma y color:SolidPeso molecular:616.77Bictegravir Sodium
CAS:Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Fórmula:C21H17F3N3NaO5Pureza:99.97%Forma y color:SolidPeso molecular:471.36NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Fórmula:C32H31N9O3SForma y color:SolidPeso molecular:621.7112-Oxocalanolide A
12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.Fórmula:C22H24O5Forma y color:SolidPeso molecular:368.429SPD-756
CAS:SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C12H16N6O3Pureza:98%Forma y color:SolidPeso molecular:292.29Carbovir triphosphate
CAS:Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].Fórmula:C11H16N5O11P3Forma y color:SolidPeso molecular:487.19HIV-IN-12
HIV-IN-12 (Compound A1) is a dual inhibitor targeting both HIV-1 Vif and reverse transcriptase (RT). It shows potential for use in HIV infection research.NNRT-IN-11
NNRT-IN-11 (14l) is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor, exhibiting EC50 values ranging from 6.50 to 52.9 nM against both wild-type (WT) and a range of HIV-1 mutant strains. NNRT-IN-11 demonstrates antiviral properties.Forma y color:Odour SolidAL-470
CAS:AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFórmula:C67H57N7O23Forma y color:SolidPeso molecular:1328.2Decanoyl-RVKR-CMK
CAS:Inhibits all seven proprotein convertases; stops proET-1 processing; hinders VGF secretion in PC12 cells.Fórmula:C34H66ClN11O5Pureza:98%Forma y color:SolidPeso molecular:744.42HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFórmula:C26H24N6O2Forma y color:SolidPeso molecular:452.51Cys-TAT(47-57)
CAS:Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Fórmula:C67H124N34O14SPureza:98%Forma y color:SolidPeso molecular:1661.99HIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Forma y color:Odour SolidHIV-IN-2
CAS:HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].Fórmula:C34H27ClF7N9O3SForma y color:SolidPeso molecular:810.14HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.Fórmula:C42H36ClF10N7O5S2Forma y color:SolidPeso molecular:1008.35Peptide T TFA
CAS:Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.Fórmula:C37H56F3N9O18Pureza:98%Forma y color:SolidPeso molecular:971.89IC-1k
IC-1k is an effective inhibitor of HIV-1, exhibiting anti-viral activity with EC50 values of 2.69 nM against HIV-1IIIB and 97.97 nM against HIV-2 ROD. Additionally, IC-1k has been noted to possess cytotoxic properties.Fórmula:C27H22F2N4O3SForma y color:SolidPeso molecular:520.55VIR-165
VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.Fórmula:C109H158N22O25S2Pureza:98%Forma y color:SolidPeso molecular:2240.7Clavirolide L
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 withoutFórmula:C20H28O3Forma y color:SolidPeso molecular:316.43
