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Proteasa del VIH

Proteasa del VIH

Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.

Se han encontrado 489 productos de "Proteasa del VIH"

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  • Etravirine D4

    CAS:
    Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.
    Fórmula:C20H15BrN6O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:439.3
  • Abacavir hydroxyacetate

    CAS:
    Abacavir hydroxyacetate is a nucleoside analog reverse transcriptase inhibitor used in the study of HIV infection.
    Fórmula:C16H20N6O3
    Pureza:98.29%
    Forma y color:Solid
    Peso molecular:344.37
  • Letrazuril

    CAS:
    Letrazuril is a compound of the anti-HIV.
    Fórmula:C17H9Cl2FN4O2
    Forma y color:Solid
    Peso molecular:391.18
  • Cabotegravir sodium

    CAS:
    Cabotegravir sodium inhibits HIV integrase (IC50: 2.5 nM), metabolized by UGT1A1, with minimal ARV interaction.
    Fórmula:C19H16F2N3NaO5
    Pureza:99.63%
    Forma y color:Solid
    Peso molecular:427.34
  • 2-Hydroxyisoquinoline-1,3(2H,4H)-dione

    CAS:
    Hydroxyisoquinoline-1,3(2H,4H)-dione (compound 6a) acts as an inhibitor of both HIV-1 integrase (IN) and HIV-1 reverse transcriptase ribonuclease H (RT RNase H), exhibiting IC50 values of 6.32 µM and 5.9 µM, respectively.
    Fórmula:C9H7NO3
    Peso molecular:177.16
  • PL 100

    CAS:
    <p>PL 100 could inhibit HIV-1 protease.</p>
    Fórmula:C33H44N4O6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:624.79
  • Cyclotriazadisulfonamide

    CAS:
    Cyclotriazadisulfonamide (CADA) is a selective, CD4-targeted HIV and Sec61 inhibitor that downregulates CD4 T-cell receptors and restricts CD4 translocation.
    Fórmula:C31H39N3O4S2
    Pureza:99.91% - 99.98%
    Forma y color:Solid
    Peso molecular:581.79
  • gardiquimod TFA salt

    CAS:
    Gardiquimod diTFA is a TLR7/8 agonist that may block HIV-1 in macrophages and PBMCs, active under 10 μM.
    Fórmula:C21H25F6N5O5
    Forma y color:Solid
    Peso molecular:541.44
  • Loviride

    CAS:
    Loviride, a reverse transcriptase inhibitor with IC50 of 0.3 μM, blocks HIV-1/2 and SIV in MT-4 cells.
    Fórmula:C17H16Cl2N2O2
    Forma y color:Solid
    Peso molecular:351.23
  • 9-Propenyladenine

    CAS:
    9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.
    Fórmula:C8H9N5
    Forma y color:Solid
    Peso molecular:175.19
  • Betulin diacetate

    CAS:
    Betulin diacetate is a bioactive chemical.
    Fórmula:C34H54O4
    Forma y color:Solid
    Peso molecular:526.8
  • Isoquinoline

    CAS:
    Compound PDK0035, with CAS No. 119-65-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0035 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
    Fórmula:C9H7N
    Peso molecular:129.15
  • Ditiocarb sodium

    CAS:
    Ditiocarb sodium (Sodium diethyldithiocarbamate) (sodium diethiocarbamate) is a copper reagent, which reacts with Cu2 + solution to form a complex and improves
    Fórmula:C5H10NNaS2
    Pureza:98.04%
    Forma y color:White Solid Crystalline
    Peso molecular:171.26
  • 2,4-Dihydroxypyridine

    CAS:
    2,4-Dihydroxypyridine: a pyridine derivative, chelates metals, assesses ion levels, measures enzymatic reactions, and quantifies biomolecules.
    Fórmula:C5H5NO2
    Pureza:97.79%
    Forma y color:White To Yellow-Beige Crystals Or
    Peso molecular:111.1
  • Tenofovir alafenamide

    CAS:
    Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.
    Fórmula:C21H29N6O5P
    Pureza:99.68% - 99.81%
    Forma y color:Solid
    Peso molecular:476.47
  • Lopinavir

    CAS:
    <p>Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation.</p>
    Fórmula:C37H48N4O5
    Pureza:98% - 99.62%
    Forma y color:White Crystalline Solid
    Peso molecular:628.8
  • LDC4297 hydrochloride

    CAS:
    LDC4297 hydrochloride is a selective and potent CDK7 inhibitor with broad-spectrum antiviral activity, useful for research on viral infections.
    Fórmula:C23H29ClN8O
    Forma y color:Solid
    Peso molecular:468.98
  • Didanosine

    CAS:
    <p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>
    Fórmula:C10H12N4O3
    Pureza:99.64%
    Forma y color:White Crystalline Powder
    Peso molecular:236.23
  • Raltegravir sodium

    CAS:
    Raltegravir (MK 0518) sodium is a potent, orally active HIV integrase (IN) inhibitor.
    Fórmula:C20H20FN6NaO5
    Forma y color:Solid
    Peso molecular:466.405
  • Temsavir

    CAS:
    <p>Temsavir (BMS626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.</p>
    Fórmula:C24H23N7O4
    Pureza:99.14%
    Forma y color:Solid
    Peso molecular:473.48