Antibacteriano

Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic,and inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the

Nifuroxazide (Diarlidan), an oral nitrofuran antidiarrheal, blocks STAT1/3/5 activation.

Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.

Framycetin sulfate (Neomycin Sulphate B) belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds.

Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.

Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.

Dichlorophen (DDM) is a nontoxic laxative vermicide of chlorinated phenol compound.

(CL227193) )binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the

Tilmicosin (EL-870), a macrolide antibiotic, treats bovine and ovine respiratory diseases in animals.

Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.

Meropenem (SM 7338), a broad-spectrum IV antibiotic, treats severe infections but may cause mild liver enzyme elevations or rare cholestatic injury.

<p>NSC-60339: AcrAB-TolC substrate, efflux pump inhibitor, potential cancer drug.</p>

Closantel (R-31520), a salicylanilide anthelmintic compound, shows different anthelmintic spectra and obvious toxicity in mammals.

Dicloxacillin Sodium hydrate is a narrow-spectrum β-Lactam antibiotic of the penicillin class, treating infections caused by susceptible Gram-positive bacteria

Cefpiramide acid (Cefpiramidum) is a third-generation cephalosporin antibiotic.

Prothionamide (1321-TH)is a thioamide derivative with antitubercular activity.

Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections.

Cefmetazole sodium: semisynthetic cephamycin, broad-spectrum, effective against infections, no severe side effects.

<p>Ronidazole (Ronidazol) is an antiprotozoal and antimicrobial agent used mainly in veterinary practice.</p>

Methicillin sodium salt is the sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity.

Amoxicillin inactivates bacterial cell wall proteins, disrupting peptidoglycan cross-linking, which weakens walls and causes cell lysis.

Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.

Bronopol (BNPD): Low-toxicity antimicrobial, highly effective against Gram-negative bacteria.

Sulfamethoxypyridazine (CL 13494) is a sulfanilamide antibacterial agent.

Nitrofurantoin, an antibiotic, targets bacteria for urinary infections by blocking DNA, RNA, and protein synthesis.

Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent, blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.

Lysostaphin is an anti-staph compound with 3 enzymes: endopeptidase, glucosamidase, amidase.

Lanopepden mesylate (GSK 1322322 mesylate) is a peptide desmethylase inhibitor with antimicrobial activity and is used in the study of pneumonia.

Pyrithione (1-hydroxyl-1H-pyridine-2-thione) is a transition metal complex, a zinc ionophore, that causes elevated zinc levels in mammalian cells.

Cefotaxime: 3rd-gen cephalosporin antibiotic, broad-spectrum, similar to ceftriaxone, sold as Claforan.

Sulfacetamide sodium monohydrate is a sulfonamide antibiotic. It has been investigated for the treatment of rosacea and pityriasis versicolor.

Fosfomycin calcium (Phosphomycin calcium salt) is a BBB penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.

Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.

Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.

Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis.

Imipenem monohydrate (Imipenem) is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall. Cost-effective and quality-assured.

Cefazolin sodium, a beta-lactam antibiotic, targets PBPs to disrupt bacterial cell wall synthesis, causing cell lysis.

Sulfamethazine sodium (Sulfadimethyldiazine Sodium Salt) salt is a sodium salt form of sulfamethazine, a sulfonamide antibiotic used in the livestock industry.

<p>Tinidazole (CP12574) is an antiprotozoal 5-nitroimidazole, metabolizing into toxic radicals that deplete sulfhydryl groups, causing DNA damage and cell death.</p>

Sulfalene (SMP2), a long-acting sulfonamide antibiotic, is used for the therapy of chronic bronchitis, urinary tract infections, and malaria.

Moxifloxacin (Avelox), a 4th-gen fluoroquinolone, fights Gram-positive/negative bacteria and drug-resistant S. pneumoniae.

<p>Sulfacetamide sodium (Sulamyd sodium) is an anti-infective agent. It is used topically to treat orally for urinary tract infections and skin infections.</p>

<p>Sarafloxacin hydrochloride (A-56620 (hydrochloride)), a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.</p>

Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.

Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.

Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis.

Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.

Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic.

Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.

Oxyclozanide (Oxyclozanid) is a salicylanilide anthelmintic used in grazing animals for fasciola and cestode infestations.

Betamipron (CS-443) is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule.

Lactitol monohydrate (D-Lactitol monohydrate) is a disaccharide analog of lactulose. It has been widely used to treat constipation and hepatic encephalopathy.

Zidebactam (WCK-5107) is an effective β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 inhibitor (IC50: 0.26 μg/mL).

Doramectin (Dectomax) is an antiparasitic agent.

Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is a broad spectrum antimicrobial agent, used in the treatment of dysentery, colitis, and gastroenteritis.

Orbifloxacin (CP-104354) is a broad-spectrum fluoroquinolone antibiotic.

Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.

Eremomycin, an antibiotic, can be used intramuscularly due to low toxicity.

MMV1578877 is an inhibitor of Mycobacterium ulcerans with an IC50 of 0.37 μM. It is applicable in research related to Buruli ulcer (BU).

(±)-Heraclenol, a coumarin derivative isolated from the fruits of Angelica lucida, exhibits antibacterial properties [1].

Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.

A 83016A is a kinamycin-type antibiotic.

<p>Platensimycin (PTM): S. platensis antibiotic, inhibits Gram-positive bacteria, blocks lipid making (IC50=0.1μM), may combat antibiotic resistance.</p>

FASN-IN-6 (compound 44), a potent fatty acid biosynthesis (FAB) inhibitor, serves as an antibacterial agent, exhibiting minimum inhibitory concentrations (MICs

Antibacterial 128, a siderophore-Ciprofloxacin blend with cleavable linker, targets P. aeruginosa and B. pseudomallei.

PMAP-23 is an antimicrobial peptide (AMP) with biological activity, derived from porcine myeloid cells.

1-Isothiocyanato-6-(methylsulfenyl)-hexane, identified in wasabi (W. japonica), exhibits multifaceted biological activities. This isothiocyanate compound demonstrates antibacterial properties by inhibiting B. subtilis growth in an agar diffusion assay at 25 µmol/disc, and antifungal effectiveness against T. mentagrophytes with a minimum inhibitory concentration (MIC) of 25 µg/ml. Additionally, it acts as a repellent in the blue mussel (M. edulis) assay and shows antifouling capabilities on polyvinyl chloride (PVC) plates at a concentration of 50 µmol/cm^2, underscoring its potential in biotechnological applications.

2,4-Dihydroxyphenylacetyl-L-asparagine is a natural product for research related to life sciences.

<p>Alliacol B is an antibiotic with mild antibacterial and antifungal properties. It can inhibit DNA synthesis in Ehrlich ascites carcinoma cells.</p>

Amoxicillin + potassium clavulanate (4:1) is a broad-spectrum, well-absorbed oral antibiotic blocking cell wall synthesis.

Chloramine-T (Chloralone) is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.

LEAP-2 (Human liver expressed antimicrobial peptide-2) is an antimicrobial peptide, a growth hormone-releasing peptide antagonist, and a GHS-R1a inverse agonist

α-Lipomycin is an acyclic polyene antibiotic isolated from the Gram-positive bacterium Streptomyces aureofaciens Tü117.

Cyclacillin (Wy-4508), an oral aminopenicillin, fights many gram-positive/negative bacteria.

Efflux pump-IN-3 inhibits AcrB, potentiates antibiotics, and is non-toxic to membranes and nematodes.

SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under

Faropenem daloxate (Faropenem medoxil) is useful for penem and antibiotics.

Pectin, a plant cell wall derived heteropolysaccharide, forms nanoparticles for delivery and acts as an antimicrobial adsorbent.

1-Ethylnaphthalene exhibits antibacterial activity and can be used in biochemical experiments and drug synthesis.

Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486). Fobrepodacin has potent bactericidal activities in vivo.

AcrB-IN-1 (Compound H6) is a highly effective inhibitor of AcrB, utilized for the reversal of bacterial multidrug resistance [1].

Dodicin hydrochloride, an effective disinfectant, demonstrates broad antimicrobial activity [1].

Rose Bengal is a photosensitizer effective against microbial cells. In the presence of light and oxygen, it inhibits the growth of yeast cells and other microorganisms, sometimes leading to their death. Rose Bengal can also limit bacterial growth, restrict the colony size of filamentous fungi, and suppress the growth of "spreading fungi" such as Rhizopus and Trichoderma.

<p>Ibericin, an anthraquinone from Prismatomeris filamentosa roots, exhibits antibacterial effects on Gram-positive and Gram-negative bacteria.</p>

Mycobactin P is one of iron(III) chelating compounds produced by most species of Mycobacteria which act as growth factors.

(R)-Eucomol, a flavonoid derivative, exhibits slight antibacterial properties and demonstrates cytotoxic activity against KB and P-388 cells [1].

Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.

<p>Showdomycin is an antibiotic with antineoplastic activity.</p>

LL-37, Human TFA (154947-66-7 free base) is a 37-residue amphipathic helical peptide, the sole human cathelicidin antimicrobial peptide, antibacterial.