Antibacteriano

Dodec-1-ene is toxic to MIAPaCa2 cells, Pseudokirchneriella subcapitata, and Daphnia magna,antibacterial. It can also be used in the synthesis of surfactants.

Glutathione S-Transferase (GST) π class inhibitor is a chemical compound designed to inhibit the action of the π class of GST enzymes.

Trans-β-terpineol, a monoterpenoid compound extracted from Schinus terebinthifolius leaves, exhibits antioxidant and antibacterial properties.

Luteoreticulin, a nitro-containing bacterial metabolite first isolated from S. luteoreticuli, exhibits mosquitocidal activity against A. aegypti at a concentration of 6.25 mg/L and nematocidal activity against C. elegans.

Kalimantacin A: a potent antibiotic effective against MRSA and other staphylococci.

Deethylindanomycin, a polyether antibiotic from S. setonii, combats Gram-positive bacteria and in vitro coccidia; ionophore selective for K+ ions.

Xenopsin precursor fragment, an antimicrobial peptide, exhibits both antibacterial/antifungal activity at concentrations ranging from 10 to 500 μg/mL and anti-

CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor.

Halocyamine B, isolated from Halocynthia roretzi, is an antibiotic peptide.

Baquiloprim: an antibiotic that inhibits bacterial dihydrofolate reductases; fights Gram-negative and Gram-positive bacteria.

Antibacterialagent 272 (Compound Z22) is a potential antibacterial agent that targets the DNA and DNA-topoisomerase II (DNA-Topo II) complex. It exhibits strong antibacterial activity, with a minimum inhibitory concentration (MIC) of 1 μg/mL against Staphylococcus aureus 25923 and 29213, 2 μg/mL against Staphylococcus epidermidis 12228, 2-4 μg/mL against Enterococcus faecalis, and 4 μg/mL against Pseudomonas aeruginosa 9027 and 27853. Antibacterialagent 272 binds by intercalating between DNA base pairs, disrupting the normal function of bacterial DNA, and is suitable for research into bacterial infectious diseases.

Amp1EP9: antimicrobial peptide, non-toxic, combats multidrug-resistant bacteria.

Urechistachykinin I (Uru-TK I) is an invertebrate kalinin-related peptide (TRPs) isolated from thylakoid nematodes.

SPR741, a cationic peptide from polymyxin B, is being developed to treat serious Gram-negative infections.

Midecamycin acetate is a broad-spectrum antibiotic active against Gram-positive and some Gram-negative strains.

Amythiamicin C is an antimicrobial antibiotic effective against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and also exhibits activity against Plasmodium falciparum (the causative agent of malaria).

ANT3310 inhibits several Serine β-Lactamases (IC50: 1-175 nM); useful for bacterial infection research.

DprE1-IN-5 (Compound 10), a potent DprE1 inhibitor, exhibits anti-TB activity with an MIC of 4 μM against the Mtb H37Rv strain and demonstrates

10-Isobutyryloxy-8,9-epoxythymol isobutyrate is a major constituent of Inula helenium and Inula royleana root cultures.

Cloflucarban can be used as a disinfectant agent.

Secnidazole hemihydrate is an oral azole antibiotic for treating amoebiasis, giardiasis, and bacterial vaginitis. It inhibits P. aeruginosa and S. marcescens.

NXL-101, an oral/IV antibiotic for Gram-positive bacteria like MRSA, was discontinued by Novexel in 2008.

2,2-Dithiobis(Benzothiazole) inhibits MAPK8 and Pseudomonas aeruginosa and is commonly used as an accelerator in rubber and plastic synthesis.

Antibacterial agent 40 is an antibacterial agent.

Maximin H4, an antimicrobial peptide originating from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits inhibitory activity against a

Cephabacin M4 is a new cephem antibiotic isolated from bacterial.

Monascorubramine, a colorant from Monascus bacteria (Talaromyces), changes hue with pH.

Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria.

Viomycin: tuberactinomycin antibiotic, halts prokaryotic protein synthesis and group I intron splicing, arrests bacterial ribosomes.

Malacidin B, a macrocyclic lipopeptide antibiotic, demonstrates calcium-dependent antibacterial activity [1] [2].

Setomimycin is an antibiotic against Gram positive bacteria, including mycobacteria.

Tomopenem is a penem antibiotic.

Dienone B is a cytotoxic secondary metabolite from tyrosine as isolated from the sponges Verongia aerophoba & Aplysina aerophoba.

Siomycin A: thiopeptide antibiotic, selectively inhibits FOXM1, anti-tumor, induces apoptosis.

Antituberculosis agent-9 (Compound 5a), an orally administered compound, demonstrates potent antitubercular activity, exhibiting a minimum inhibitory

Phanerosporic acid, from P. chrysosporum, fights bacteria like B. cereus and fungi including C. cladosporioides; used in macrolide synthesis.

Xinjiachalcone A, from Glycyrrhiza inflata, kills H. pylori effectively (MIC: 12.5-50 μM, 17 strains).

Polyphemusin II is an antimicrobial peptide isolated from the blood cells of the American horseshoe crab. It exhibits antimicrobial activity against a variety of Gram-positive and Gram-negative bacteria, as well as fungi.

BAL30072: Antibiotic effective against MDR Acinetobacter (4 μg/mL) and P. aeruginosa (8 μg/mL); a monocyclic beta-lactam.

Loloatin B 10 is a bioactive chemical.

Antibacterial agent 132 showed antimicrobial activity against C.

Arginomycin is a nucleoside antibiotic (antibiotic) that inhibits the growth of Gram-positive bacteria and fungi in vitro.

Altertoxin III is a mutagenic agent that induces mutations in Salmonella typhimurium strains TA98, TA100, and TA1537. It is isolated from extracts of A. alternata strains that demonstrate mutagenic responses in the Ames Salmonella typhimurium test.

Cyclic L27-11 is a cyclic peptide analog antibiotic that exhibits potent antimicrobial activity against specific bacteria, particularly Pseudomonas sp. It is highly effective against Pseudomonas aeruginosa, demonstrating nanomolar-level antibacterial activity. The mechanism of action for Cyclic L27-11 involves interfering with the function of the bacterial outer membrane protein LptD, inhibiting the normal transport of lipopolysaccharide (LPS). This inhibition leads to the accumulation of membrane-like substances within the bacterial cell, adversely affecting bacterial survival. Consequently, Cyclic L27-11 is a promising candidate for antimicrobial agent development.

Kapurimycin A3 is an antitumor antibiotics.

Aurein 2.6, an antibiotic antimicrobial peptide, exhibits activity against various Gram-positive bacteria with minimum inhibitory concentrations (MIC) of 25, 25

Neamine: antibiotic, anti-angiogenic, battles bacteria, cancer, protects nerves.

1-Methyl-2-tridecenylquinolinone fights H. pylori (MIC50: 22 µM, MIC90: 50 µM); may research ulcers.