Antibacteriano
Los inhibidores antibacterianos son compuestos que atacan las células bacterianas, inhibiendo su crecimiento o matándolas directamente. Estos inhibidores son esenciales en el desarrollo de tratamientos para infecciones bacterianas y se utilizan ampliamente en la investigación para estudiar la fisiología bacteriana, los mecanismos de resistencia y la eficacia de nuevos agentes antibacterianos. En CymitQuimica, ofrecemos una gama de inhibidores antibacterianos para apoyar su investigación en microbiología, enfermedades infecciosas y desarrollo de medicamentos.
Se han encontrado 2949 productos de "Antibacteriano"
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Cetefloxacin
CAS:<p>Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.</p>Fórmula:C20H16F3N3O3Peso molecular:403.35MtTMPK-IN-1
<p>MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.</p>Fórmula:C22H24N4O3Forma y color:SolidPeso molecular:392.45Antitubercular agent-23
<p>Antitubercular agent-23 combats Candida albicans (MIC: 1.1 μg/ml) and M. tuberculosis (MIC: 1 μg/ml).</p>Fórmula:C20H22FN5O8SForma y color:SolidPeso molecular:511.48Antibacterial agent 79
<p>Antibacterial agent 79 is an antibacterial agent.</p>Fórmula:C18H27N3O2S3Forma y color:SolidPeso molecular:413.62Ibafloxacine
CAS:<p>Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against</p>Fórmula:C15H14FNO3Pureza:97.67%Forma y color:SolidPeso molecular:275.27Enzyme-IN-3 disodium
CAS:<p>Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.</p>Fórmula:C20H13N3Na2O8S2Forma y color:SolidPeso molecular:533.442epi-D-Captopril
CAS:<p>epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.</p>Fórmula:C9H15NO3SForma y color:SolidPeso molecular:217.285WQ3810
CAS:<p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>Fórmula:C22H22F3N5O3Pureza:98%Forma y color:SolidPeso molecular:461.44RNAP-σ interaction inhibitor-1
CAS:<p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>Fórmula:C19H11Cl3N2O6S2Forma y color:SolidPeso molecular:533.792'-Amino-2'-deoxyadenosine
CAS:<p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>Fórmula:C10H14N6O3Peso molecular:266.26Meclocycline
CAS:<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Fórmula:C22H21ClN2O8Forma y color:SolidPeso molecular:476.86Antibacterial agent 75
<p>Antibacterial agent 75 re-sensitizes VRSA to vancomycin.</p>Fórmula:C22H28N6OForma y color:SolidPeso molecular:392.5Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Fórmula:C17H12BrFN4O2SForma y color:SolidPeso molecular:435.27Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Fórmula:C16H11F2N3Forma y color:SolidPeso molecular:283.28Nitrovin
CAS:<p>Nitrovin is an antimicrobial growth promoter that induces ROS-mediated non-apoptotic and quasi-apoptotic cell death by targeting TrxR1. It exhibits anticancer activity with IC50 values ranging from 1.31 to 6.60 μM for both tumor and normal cells.</p>Fórmula:C14H12N6O6Forma y color:SolidPeso molecular:360.28Streptothricin F
CAS:<p>Streptothricin F is a biochemical.</p>Fórmula:C19H34N8O8Forma y color:SolidPeso molecular:502.52TBAJ-5307
CAS:<p>TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].</p>Fórmula:C30H35BrN4O6Forma y color:SolidPeso molecular:627.53BDM91288
CAS:<p>BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].</p>Fórmula:C17H22ClN5Forma y color:SolidPeso molecular:331.84Antibiotic U 44590
CAS:<p>5,6-Dihydro-5-azathymidine exhibits activity against both Gram-positive and Gram-negative bacteria, as well as DNA viruses.</p>Fórmula:C9H15N3O5Forma y color:SolidPeso molecular:245.23Anti-MRSA agent 23
CAS:<p>Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.</p>Fórmula:C20H17N5O3SForma y color:SolidPeso molecular:407.446Kendomycin
CAS:<p>Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.</p>Fórmula:C29H42O6Forma y color:SolidPeso molecular:486.64NDM-1 inhibitor-5
CAS:<p>NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].</p>Fórmula:C24H23NO4Forma y color:SolidPeso molecular:389.44Levofloxacin mesylate
CAS:<p>Levofloxacin mesylate is an orally active antibiotic effective against both Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase and topoisomerase IV enzymes. Levofloxacin mesylate is employed in research related to chronic periodontitis, airway inflammation, and BK viremia. Additionally, it possesses anti-Orthopoxvirus activity.</p>Fórmula:C19H24FN3O7SForma y color:SolidPeso molecular:457.473Antibacterial agent 204
CAS:<p>Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].</p>Fórmula:C14H18N2Forma y color:SolidPeso molecular:214.31DL-2-Aminopimelic Acid
CAS:<p>DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.</p>Fórmula:C7H13NO4Forma y color:SolidPeso molecular:175.18Antitubercular agent-13
<p>Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.</p>Fórmula:C18H18N4O5Forma y color:SolidPeso molecular:370.36Antibacterial agent 81
CAS:<p>Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.</p>Fórmula:C33H28N2O8Forma y color:SolidPeso molecular:580.58Pneumolysin-IN-1
CAS:<p>Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].</p>Fórmula:C23H16Cl2N2O4Forma y color:SolidPeso molecular:455.29LasR antagonist 1
CAS:<p>LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].</p>Fórmula:C20H15F3N2O3Forma y color:SolidPeso molecular:388.34L 689065
CAS:<p>L 689065 is a 5-lipoxygenase inhibitor.</p>Fórmula:C35H33ClN2O3SPureza:98%Forma y color:SolidPeso molecular:597.17MA220607
CAS:<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Fórmula:C34H38INForma y color:SolidPeso molecular:587.58Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Fórmula:C15H16BFO6Forma y color:SolidPeso molecular:322.093Diploicin
CAS:<p>Diploicin is a dibenzofuran lactone compound with activity against Gram-positive bacteria, found in lichens (lichens).</p>Fórmula:C16H10Cl4O5Forma y color:SolidPeso molecular:424.06HKI12134085
CAS:<p>HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].</p>Fórmula:C18H18F3N3O5SForma y color:SolidPeso molecular:445.41Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Fórmula:C14H11N5O4S2Forma y color:SolidPeso molecular:377.4Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Fórmula:C21H29FN2Forma y color:SolidPeso molecular:328.47N-Cbz-L-Cysteine
CAS:<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Fórmula:C11H13NO4SForma y color:SolidPeso molecular:255.29QPX7728 bis-acetoxy methyl ester
CAS:<p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>Fórmula:C15H14BFO8Pureza:98%Forma y color:SolidPeso molecular:352.08Ro 24-4383
CAS:<p>Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.</p>Fórmula:C32H31FN8O10S2Pureza:98%Forma y color:SolidPeso molecular:770.76BRL-42715
CAS:<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Fórmula:C10H7N4NaO3SPureza:98%Forma y color:SolidPeso molecular:286.24MBL-IN-5
CAS:<p>MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.</p>Fórmula:C20H16ClNO3Forma y color:SolidPeso molecular:353.80MK-3402
CAS:<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Fórmula:C15H19N9O5S2Forma y color:SolidPeso molecular:469.50Antifungal agent 38
<p>Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.</p>Fórmula:C8H12N2S2Forma y color:SolidPeso molecular:200.32H052
CAS:<p>H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.</p>Fórmula:C21H15ClFN3O4SForma y color:SolidPeso molecular:459.88LasR-IN-1
<p>LasR-IN-1 (9g) strongly inhibits LasR, potent vs E. coli, with a 28.13 μM MIC against P. aeruginosa.</p>Fórmula:C23H21N3O2Forma y color:SolidPeso molecular:371.43OSUAB-0284
CAS:<p>OSUAB-0284 is an inhibitor of bacterial topoisomerase. It exhibits significant activity against staphylococci, particularly methicillin-resistant Staphylococcus aureus (MRSA). The compound exerts its antibacterial effect by inhibiting bacterial topoisomerase and may be used in research on infections caused by drug-resistant bacteria, including MRSA.</p>Fórmula:C22H23FN6O6Forma y color:SolidPeso molecular:486.45Antibacterial agent 278
CAS:<p>Antibacterialagent 278 (compound B1) is an antimicrobial agent that exhibits potent inhibitory activity against Gram-positive bacteria.</p>Fórmula:C24H17ClF2N4O3Forma y color:SolidPeso molecular:482.87Palmitanilide
CAS:<p>Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.</p>Fórmula:C22H37NOForma y color:SolidPeso molecular:331.535(R)-ZG197
<p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>Fórmula:C28H35F3N4O3Forma y color:SolidPeso molecular:532.6Cefclidin
CAS:<p>Cefclidin (Cefclidine) is a cephalosporin compound.</p>Fórmula:C21H26N8O6S2Forma y color:SolidPeso molecular:550.611
