Antibacteriano
Los inhibidores antibacterianos son compuestos que atacan las células bacterianas, inhibiendo su crecimiento o matándolas directamente. Estos inhibidores son esenciales en el desarrollo de tratamientos para infecciones bacterianas y se utilizan ampliamente en la investigación para estudiar la fisiología bacteriana, los mecanismos de resistencia y la eficacia de nuevos agentes antibacterianos. En CymitQuimica, ofrecemos una gama de inhibidores antibacterianos para apoyar su investigación en microbiología, enfermedades infecciosas y desarrollo de medicamentos.
Se han encontrado 2949 productos de "Antibacteriano"
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844-TFM
<p>844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.</p>Fórmula:C24H25F3N4O2Forma y color:SolidPeso molecular:458.48Antitubercular agent-29
<p>Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.</p>Fórmula:C20H12ClN3O5Forma y color:SolidPeso molecular:409.78OPC-167832
CAS:<p>OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.</p>Fórmula:C21H20ClF3N2O4Forma y color:SolidPeso molecular:456.847-Hydroxytropolone
CAS:<p>7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.</p>Fórmula:C7H6O3Forma y color:SolidPeso molecular:138.12(4-Aminobenzoyl)-D-glutamic acid
CAS:<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Fórmula:C12H14N2O5Forma y color:SolidPeso molecular:266.25Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Fórmula:C7H14N3NaO8SForma y color:SolidPeso molecular:323.26Antibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Fórmula:C16H23N3S2Forma y color:SolidPeso molecular:321.5Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Fórmula:C18H23N5OSForma y color:SolidPeso molecular:357.47PF 03709270
CAS:<p>PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.</p>Fórmula:C19H27NO7S3Pureza:98%Forma y color:SolidPeso molecular:477.61Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Fórmula:C31H44N2O6SForma y color:SolidPeso molecular:572.76Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Fórmula:C21H27N3SForma y color:SolidPeso molecular:353.52VEGFR-2/DHFR-IN-1
<p>Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.</p>Fórmula:C20H18ClNO4Forma y color:SolidPeso molecular:371.81Elongation factor P-IN-2
<p>Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.</p>Fórmula:C16H35N3O2Forma y color:SolidPeso molecular:301.47N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:<p>N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.</p>Fórmula:C17H19N5O5Forma y color:SolidPeso molecular:373.363VEGFR-2/DHFR-IN-2
<p>VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.</p>Fórmula:C21H21NO4Forma y color:SolidPeso molecular:351.4Rubropunctatin
CAS:<p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>Fórmula:C21H23NO4Forma y color:SolidPeso molecular:353.41BM635 mesylate
<p>BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.</p>Fórmula:C26H33FN2O4SForma y color:SolidPeso molecular:488.61(E)-Cefodizime
CAS:<p>(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.</p>Fórmula:C20H20N6O7S4Forma y color:SolidPeso molecular:584.669RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Fórmula:C22H26BrN5O4SForma y color:SolidPeso molecular:536.44Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Fórmula:C19H21N5O2SForma y color:SolidPeso molecular:383.47LpxC-IN-10
CAS:<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Fórmula:C30H31N5O3Forma y color:SolidPeso molecular:509.6LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Fórmula:C22H19N3O2Forma y color:SolidPeso molecular:357.41PqsR-IN-2
<p>PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.</p>Fórmula:C18H20ClN3OSForma y color:SolidPeso molecular:361.89MtMetAP1-IN-1
<p>MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.</p>Fórmula:C15H10BrN5O2SForma y color:SolidPeso molecular:404.24MtTMPK-IN-3
CAS:<p>MtTMPK-IN-3 inhibits Mycobacterium tuberculosis kinase with IC50 0.12μM, MIC 12.5μM on Mtb, cytotoxic EC50 12.5μM on MRC-5 cells.</p>Fórmula:C23H23Cl2N3O3Forma y color:SolidPeso molecular:460.35FG-2101
CAS:<p>FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.</p>Fórmula:C30H32N5O6PForma y color:SolidPeso molecular:589.579Antibacterial agent 77
<p>Antibacterial agent 77 (compound 12) is an antibacterial agent [1].</p>Fórmula:C22H27N3OSForma y color:SolidPeso molecular:381.53GSK-3036656 free base
CAS:<p>GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.</p>Fórmula:C10H13BClNO4Forma y color:SolidPeso molecular:257.48PptT-IN-3
<p>PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.</p>Fórmula:C16H27N5O3SForma y color:SolidPeso molecular:369.48Cefoxazole
CAS:<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Fórmula:C21H18ClN3O7SForma y color:SolidPeso molecular:491.902RhlR antagonist 1
<p>RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.</p>Fórmula:C12H10F2OForma y color:SolidPeso molecular:208.2MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Fórmula:C26H35FN16O2Pureza:98%Forma y color:SolidPeso molecular:622.66MtTMPK-IN-7
<p>MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.</p>Fórmula:C27H29ClN6O3Forma y color:SolidPeso molecular:521.01Antitubercular agent-11
<p>Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].</p>Fórmula:C16H15N3O4Forma y color:SolidPeso molecular:313.31Antibacterial agent 279
CAS:<p>Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.</p>Fórmula:C9H11NO2SForma y color:SolidPeso molecular:197.25MtTMPK-IN-2
CAS:<p>MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).</p>Fórmula:C23H24ClN3O3Forma y color:SolidPeso molecular:425.91Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Fórmula:C25H18N2O2SForma y color:SolidPeso molecular:410.49NFC nitro probe 1
CAS:<p>NFC nitro probe 1 (compound 18) is a chemical probe designed for the detection of Mtb, exhibiting high potency against both R-Mtb and NR-Mtb.</p>Fórmula:C19H19NO6Forma y color:SolidPeso molecular:357.357Probenecid sodium
CAS:<p>Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.</p>Fórmula:C13H18NNaO4SForma y color:SolidPeso molecular:307.341Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Fórmula:C25H24O9Forma y color:SolidPeso molecular:468.453Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Fórmula:C24H33BrN2O2Forma y color:SolidPeso molecular:461.44Antibacterial agent 262
CAS:<p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>Fórmula:C17H18F2N6O4S3Forma y color:SolidPeso molecular:504.554Cephalosporin C
CAS:<p>Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.</p>Fórmula:C16H21N3O8SForma y color:SolidPeso molecular:415.418Colistin adjuvant-2
<p>Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].</p>Fórmula:C14H7Cl2F3N2OForma y color:SolidPeso molecular:347.12MurA-IN-6
CAS:<p>MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 of 26.63 μM. It exhibits antibacterial activity by inhibiting the function of MurA, a key protein essential for bacterial cell wall synthesis.</p>Fórmula:C22H17N3O3SForma y color:SolidPeso molecular:403.4544-Bromo A23187
CAS:<p>4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.</p>Fórmula:C29H36BrN3O6Pureza:98%Forma y color:SolidPeso molecular:602.52NBTIs-IN-5
CAS:<p>NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.</p>Fórmula:C24H25F3N4O2Forma y color:SolidPeso molecular:458.48Deprodone
CAS:<p>Deprodone is an active compound that inhibits key processes such as bacterial cell wall synthesis by interacting with hydrolase and transferase proteins of methicillin-resistant Staphylococcus aureus (MRSA). It is applied in the research of MRSA infections, inflammatory skin diseases, intestinal disorders, and fatty acid metabolism disorders.</p>Fórmula:C21H28O4Forma y color:SolidPeso molecular:344.44Diclosulam
CAS:<p>Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.</p>Fórmula:C13H10Cl2FN5O3SForma y color:SolidPeso molecular:406.22Anthelvencin A
CAS:<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Fórmula:C19H25N9O3Forma y color:SolidPeso molecular:427.46
