Antibacteriano
Los inhibidores antibacterianos son compuestos que atacan las células bacterianas, inhibiendo su crecimiento o matándolas directamente. Estos inhibidores son esenciales en el desarrollo de tratamientos para infecciones bacterianas y se utilizan ampliamente en la investigación para estudiar la fisiología bacteriana, los mecanismos de resistencia y la eficacia de nuevos agentes antibacterianos. En CymitQuimica, ofrecemos una gama de inhibidores antibacterianos para apoyar su investigación en microbiología, enfermedades infecciosas y desarrollo de medicamentos.
Se han encontrado 3303 productos para "Antibacteriano".
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Candicidin
CAS:Candicidin, a heptaene macrolide from S. griseus or A. levoris, treats candidiasis topically. Mainly candicidin D.Fórmula:C59H84N2O18Pureza:98%Forma y color:SolidPeso molecular:1109.317SAAP 148 TFA
SAAP 148, an antimicrobial peptide, effectively combats various multidrug-resistant bacteria in vitro and, in vivo, reduces skin colony-forming units (CFUs) inFórmula:C157H261N49O27·XCF3COOHForma y color:SolidPeso molecular:3267.10Naphthalene
CAS:Producto controladoNaphthalene is the simplest polycyclic aromatic hydrocarbon (PAH) and a major component of coal tar, serving as an insect repellent in camphor ballsFórmula:C10H8Pureza:99.94%Forma y color:SolidPeso molecular:128.172,4-Dihydroxyphenylacetyl-L-asparagine
CAS:2,4-Dihydroxyphenylacetyl-L-asparagine is a natural product for research related to life sciences.Fórmula:C12H14N2O6Forma y color:SolidPeso molecular:282.252Kitasamycin tartrate
CAS:Kitasamycin tartrate, a macrolide antibiotic produced by Streptomyces kitasatoensis, has a wide spectrum of antimicrobial activity.Fórmula:C40H67NO18Pureza:98%Forma y color:SolidPeso molecular:849.965Citrocin
Citrocin is a potent inhibitor of bacterial RNA polymerase (RNAP). It exhibits significant inhibitory effects on Escherichia coli RNA polymerase, with a MIC range of 16–125 μM. Citrocin specifically binds to RNA polymerase, inhibiting its activity and thus blocking the bacterial transcription process. It predominantly enters cells through the inner membrane protein SbmA. Citrocin holds potential for research on infections caused by Gram-negative bacteria, such as enterohemorrhagic E. coli.Forma y color:Odour SolidTuberculosis inhibitor 11
Compound 14, also known as Tuberculosis Inhibitor 11, enhances the antimycobacterial efficacy of antitubercular agent [1].Forma y color:Odour SolidPlatensimycin
CAS:Platensimycin (PTM): S. platensis antibiotic, inhibits Gram-positive bacteria, blocks lipid making (IC50=0.1μM), may combat antibiotic resistance.Fórmula:C24H27NO7Forma y color:SolidPeso molecular:441.47NSC 55655
CAS:NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) has antimicrobial activity, inhibits the proliferation of C. albicans, and is used in diabetes.Fórmula:C10H6N2O4SPureza:99.39%Forma y color:SolidPeso molecular:250.23Tazobactam sodium
CAS:Tazobactam sodium,β-Lactamase inhibitor.Fórmula:C10H11N4NaO5SPureza:98.56%Forma y color:SolidPeso molecular:322.27Sedecamycin
CAS:Sedecamycin is a 17-membered macrolide antibiotic. It is used for treating swine dysentery.Fórmula:C27H35NO8Pureza:98%Forma y color:SolidPeso molecular:501.576FtsZ-IN-8
FtsZ-IN-8: Strong FtsZ inhibitor, blocks bacterial cell division, low resistance risk, minimal toxicity to mammalian cells.Fórmula:C27H28BrN3O2Forma y color:SolidPeso molecular:506.43NAB815
CAS:NAB815 is a specific inhibitor of Stx2a (Kd= 0.01 μM)/TLR4 interactions. It inhibits the interaction between neutrophils and Stx2a with an IC50 of 0.057 μg/mL. NAB815 also prevents the formation of extracellular vesicles (EV) containing Stx2 from leukocytes and platelets, reducing its toxicity in cells (Vero cells) and in animal models (CD-1 mice). Additionally, NAB815 decreases the bacterial load in the kidneys, urine, and bladder of mice infected with Escherichia coli. It is applicable for research in hemolytic uremic syndrome (HUS).Fórmula:C55H94N14O14Forma y color:SolidPeso molecular:1175.428-Br-GTP tetrasodium
8-Br-GTP (tetrasodium) [8-Bromoguanosine-5'-triphosphate (tetrasodium)] is a derivative of the energy substrate GTP, utilized in protein synthesis and gluconeogenesis. It inhibits the E. coli GTPase FtsZ with a Ki value of 31.8 μM and promotes the assembly of microtubules in pig brains.Forma y color:Odour Solidtrans-β-Terpineol
CAS:Trans-β-terpineol, a monoterpenoid compound extracted from Schinus terebinthifolius leaves, exhibits antioxidant and antibacterial properties.Fórmula:C10H18OForma y color:SolidPeso molecular:154.25MtbHU-IN-1
CAS:MtbHU-IN-1 is a Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU)inhibitor(binding to WT MtbHU with a Kd of 98 nM).Fórmula:C44H36N4O12S2Pureza:98%Forma y color:SolidPeso molecular:876.91Anacardic Acid Diene
CAS:Polyunsaturated anacardic acid diene from cashew shells fights MRSA, S. mutans, and S. mansoni; inhibits soybean lipoxygenase-1.Fórmula:C22H32O3Forma y color:SolidPeso molecular:344.49Brilacidin tetrahydrochloride
CAS:Brilacidin tetrahydrochloride is a synthetic antibiotic effective against multiple bacteria with MIC90 values ranging from 1 to 8 μg/mL.Fórmula:C40H54Cl4F6N14O6Forma y color:SolidPeso molecular:1082.75Urechistachykinin I
CAS:Urechistachykinin I (Uru-TK I) is an invertebrate kalinin-related peptide (TRPs) isolated from thylakoid nematodes.Fórmula:C50H85N19O14Pureza:98%Forma y color:SolidPeso molecular:1176.33Periplanetasin-2
CAS:Periplanetasin-2 is an antimicrobial peptide that induces oxidative stress by generating reactive oxygen species (ROS) and initiating lipid peroxidation. Additionally, Periplanetasin-2 can trigger apoptosis.Fórmula:C84H134N22O17SForma y color:SolidPeso molecular:1756.17Dienone B
CAS:Dienone B is a cytotoxic secondary metabolite from tyrosine as isolated from the sponges Verongia aerophoba & Aplysina aerophoba.Fórmula:C8H7Br2NO3Forma y color:SolidPeso molecular:324.95KPC-2-IN-3
KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with an IC50 of 0.533 μM and a Ki of 0.194 μM. It works synergistically with Meropenem to exhibit antibacterial activity against carbapenem-resistant K. pneumoniae K47-25, reducing bacterial count and demonstrating a post-antibiotic effect. Additionally, KPC-2-IN-3 significantly decreases lung bacterial load in a mouse pneumonia model.Forma y color:Odour SolidTomopenem
CAS:Tomopenem is a penem antibiotic.Fórmula:C23H35N7O6SPureza:98%Forma y color:SolidPeso molecular:537.63Viquidacin
CAS:NXL-101, an oral/IV antibiotic for Gram-positive bacteria like MRSA, was discontinued by Novexel in 2008.Fórmula:C25H29FN2O4S2Forma y color:SolidPeso molecular:504.64CRAMP (1-39)
CRAMP (1-39) is an antimicrobial peptide that demonstrates potent bactericidal effects against various Neisseria meningitidis strains in vitro. CRAMP (1-39) is applicable in research focused on drug-resistant bacterial infections.Fórmula:C202H346N58O52Forma y color:SolidPeso molecular:4416.621314-Epianhydrotetracycline hydrochloride
CAS:EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.Fórmula:C22H23ClN2O7Forma y color:SolidPeso molecular:462.88Xenopsin precursor fragment
CAS:Xenopsin precursor fragment, an antimicrobial peptide, exhibits both antibacterial/antifungal activity at concentrations ranging from 10 to 500 μg/mL and anti-Fórmula:C123H211N33O32Pureza:98%Forma y color:SolidPeso molecular:2664.19(RXR)4XB TFA
(RXR)4XB TFA is a cell-penetrating peptide that binds phosphorodiamidate morpholino oligomer (PMO) to create a peptide-conjugated PMO (PPMO) for enhanced delivery into bacterial cells. The (RXR)4XB TFA-PMO complex inhibits biofilm formation, suppresses Pseudomonas aeruginosa with a MIC50 of 0.5-16 μM, and reduces bacterial load in a mouse acute pneumonia model.Forma y color:Odour SolidMaximin H5
CAS:Maximin H5, an antimicrobial peptide from Bombina maxima [1], possesses antibacterial properties.Fórmula:C93H161N21O28Forma y color:SolidPeso molecular:2021.4SAAP 148
SAAP 148 is an antimicrobial and antibiofilm agent that demonstrates inhibitory activity against antibiotic-resistant pathogens, with an LC50 of 0.8-12.8 μM.Fórmula:C157H261N49O27Forma y color:SolidPeso molecular:3265.05565LZ1 peptide
CAS:LZ1 peptide is an antimicrobial peptide with antimalarial activity [1].Fórmula:C113H167N33O15Forma y color:SolidPeso molecular:2227.75Methyl quinoline-2-carboxylate
CAS:Methyl quinoline-2-carboxylate (Methyl 2-quinolinecarboxylate) inhibits the binding of Mycobacterium tuberculosis.Fórmula:C11H9NO2Pureza:99.13%Forma y color:SolidPeso molecular:187.19Narasin (sodium salt)
CAS:Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells andFórmula:C43H71NaO11Pureza:98%Forma y color:White SolidPeso molecular:787.01Cys-LL37
Cys-LL37 is a biomaterial with antibacterial properties developed by covalently attaching it to titanium surfaces. It utilizes a flexible, hydrophilic polyethylene glycol spacer and selectively N-terminally couples LL37 to create a surface peptide layer that kills bacteria upon contact. Cys-LL37 can be employed in the development of new antimicrobial biomaterials.Fórmula:C208H345N61O54SForma y color:SolidPeso molecular:4593.58461Antibacterial agent 284
Antibacterialagent 284 (Compound 7) is an antibacterial agent with a zinc-binding structure, showing potent inhibitory activity against the Legionella pneumophila metalloprotease ProA, with an IC50 of 0.96 μM. It effectively inhibits the cleavage of type IV collagen and flagellin (ProA substrates), and reduces immune evasion within the TLR5-NF-κB pathway and neutrophil (PMN)-mediated inflammation in human lung tissue explants. Antibacterialagent 284 holds potential for Legionnaires' disease research.Forma y color:Odour SolidSitafloxacin
CAS:Sitafloxacin: potent broad-spectrum oral fluoroquinolone effective against resistant strains.Fórmula:C19H18ClF2N3O3Pureza:99.65%Forma y color:Yellow SolidPeso molecular:409.81SYNV-cyclo(CGGYF) TFA
SYNV-cyclo(CGGYF) TFA: a S. hominis autoinducer that inhibits S. aureus, may help research into S. aureus-related damage.Fórmula:C48H59F3N10O15SForma y color:SolidPeso molecular:1105.1Lucidin ethyl ether
CAS:Ibericin, an anthraquinone from Prismatomeris filamentosa roots, exhibits antibacterial effects on Gram-positive and Gram-negative bacteria.Fórmula:C17H14O5Forma y color:SolidPeso molecular:298.29Microcin J25
CAS:Microcin J25 (MccJ25) is a cyclic peptide antibiotic from E. coli that inhibits DNA-dependent RNA polymerase and exhibits antibacterial activity.Fórmula:C101H139N23O27Forma y color:White SolidPeso molecular:2107.32AcrAP1
AcrAP1 (AP1-Z1) is an antimicrobial peptide found in the venom of the Arabian scorpion (Androctonus crassicauda). It exhibits antibacterial properties, effectively inhibiting the growth of both Gram-positive and Gram-negative bacteria, as well as yeasts. AcrAP1 also displays antitumor activity by promoting apoptosis in cancer cells and inhibiting angiogenesis, making it a potential candidate for cancer treatment research.Fórmula:C97H150N22O21Forma y color:SolidPeso molecular:1959.13459Temporin A acetate
Temporin A acetate is a natural short α-helical antimicrobial peptide against Gram-positive bacteria and fungi.Fórmula:C70H121N17O16Pureza:99.96%Forma y color:White SolidPeso molecular:1456.84IDR-HH2
CAS:IDR-HH2 is an immunoregulatory peptide with the ability to modulate the host cytokine/chemokine environment. It enhances the adhesion of monocytes and THP-1 cells to fibronectin. Additionally, IDR-HH2 exhibits antibacterial activity, inhibiting P. aeruginosa and S. aureus with MIC values of 75 µg/mL and 38 µg/mL, respectively.Fórmula:C62H117N23O13Forma y color:SolidPeso molecular:1392.74G(IIKK)3I-NH2
CAS:G(IIKK)3I-NH2 is an antimicrobial peptide with potent efficacy against both Gram-negative and Gram-positive bacteria. It demonstrates low toxicity in primary cells and mice, and has a minimal tendency to induce bacterial resistance. G(IIKK)3I-NH2 is applicable in the study of anti-infective drugs.Fórmula:C80H155N21O14Forma y color:SolidPeso molecular:1635.22Brevinin-1Ea
CAS:Brevinin-1Ea, an antimicrobial peptide, originates from the skin secretions of the European green frog (Rana esculenta) [1].Fórmula:C123H206N30O28S3Forma y color:SolidPeso molecular:2649.33D2A21 TFA
D2A21 TFA is an antimicrobial peptide that exhibits significant antibacterial activity against Pseudomonas, and it possesses bactericidal properties on burn eschar. It also has antitumor properties and can be utilized in prostate cancer research.Forma y color:Odour SolidN-Acetyl-D-mannosamine-13C
N-Acetyl-D-mannosamine-13C is the carbon-13 labeled version of N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (T19655) (ManNAc) is a critical precursor to N-acetylneuraminic acid (NeuAc) and plays a role as a specific monomer of bacterial capsular polysialic acid (PA). It is metabolized into ManNAc-6-phosphate and GlcN through the actions of GNE and GlcNAc 2-epimerase (renin-binding protein, RnBP).Forma y color:Odour SolidGCO-(GPO)10-GCOG
GCO-(GPO)10-GCOG is a polypeptide containing GPO repeat sequences, exhibiting a collagen-like single collagen triple-helix structure. The cross-linked triple-helix GCO-(GPO)10-GCOG can form collagen-related peptide (CRP) mimetics that closely bind Yersinia adhesin YadA. YadA mediates the adhesion of the human intestinal pathogen Yersinia enterocolitica to collagen and other extracellular matrix components, potentially disrupting host processes mediated by endogenous collagen-binding proteins. GCO-(GPO)10-GCOG is useful for studying YadA-related infections.Forma y color:Odour SolidDodicin hydrochloride
CAS:Dodicin hydrochloride, an effective disinfectant, demonstrates broad antimicrobial activity [1].Fórmula:C18H39N3O2·xHClForma y color:SolidColistin
CAS:Colistin: polypeptide antibiotic for Gram-negative bacteria, including drug-resistant strains, but may cause nephrotoxicity.Fórmula:C53H100N16O13(forE1)Forma y color:SolidPeso molecular:1169.5Midecamycin acetate
CAS:Midecamycin acetate is a broad-spectrum antibiotic active against Gram-positive and some Gram-negative strains.Fórmula:C45H71NO17Pureza:98%Forma y color:SolidPeso molecular:898.04
