Antibacteriano
Los inhibidores antibacterianos son compuestos que atacan las células bacterianas, inhibiendo su crecimiento o matándolas directamente. Estos inhibidores son esenciales en el desarrollo de tratamientos para infecciones bacterianas y se utilizan ampliamente en la investigación para estudiar la fisiología bacteriana, los mecanismos de resistencia y la eficacia de nuevos agentes antibacterianos. En CymitQuimica, ofrecemos una gama de inhibidores antibacterianos para apoyar su investigación en microbiología, enfermedades infecciosas y desarrollo de medicamentos.
Se han encontrado 3362 productos de "Antibacteriano"
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Alpibectir
CAS:Alpibectir has antibacterial activity [1].Fórmula:C12H14F6N2O2Forma y color:SolidPeso molecular:332.24BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Fórmula:C26H33FN2O4SForma y color:SolidPeso molecular:488.61PptT-IN-3
PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.Fórmula:C16H27N5O3SForma y color:SolidPeso molecular:369.48RhlR antagonist 1
RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.Fórmula:C12H10F2OForma y color:SolidPeso molecular:208.2MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Fórmula:C23H18Cl2FNO3Forma y color:SolidPeso molecular:446.3Enzyme-IN-3 disodium
CAS:Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.Fórmula:C20H13N3Na2O8S2Forma y color:SolidPeso molecular:533.442Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Fórmula:C16H15N3O4Forma y color:SolidPeso molecular:313.31ZG297
CAS:ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.Fórmula:C31H35F3N4O3Forma y color:SolidPeso molecular:568.63MtTMPK-IN-2
CAS:MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Fórmula:C23H24ClN3O3Forma y color:SolidPeso molecular:425.91Metallo-β-lactamase-IN-16
CAS:Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.Fórmula:C16H16N8O4S3Forma y color:SolidPeso molecular:480.54NDM-1 inhibitor-5
CAS:NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].Fórmula:C24H23NO4Forma y color:SolidPeso molecular:389.44Antibacterial agent 204
CAS:Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].Fórmula:C14H18N2Forma y color:SolidPeso molecular:214.31Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Fórmula:C24H28FN5O8Forma y color:SolidPeso molecular:533.51Antitubercular agent-29
Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.Fórmula:C20H12ClN3O5Forma y color:SolidPeso molecular:409.78Rf470 TFA
CAS:Rf470 (Rotor NO.4) TFA is an FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently integrated into bacterial peptidoglycan. In its free state, Rf470 TFA exhibits weak fluorescence, which significantly increases upon integration into peptidoglycan by transpeptidase catalysis. This fluorescence change allows Rf470 TFA to be used for real-time monitoring of peptidoglycan biosynthesis, detecting transpeptidase activity, and screening antibiotics.Fórmula:C28H31F3N4O7SForma y color:SolidPeso molecular:624.63MetRS-IN-1
CAS:MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Fórmula:C15H13N3O4SForma y color:SolidPeso molecular:331.35Mt KARI-IN-1
Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.Fórmula:C14H11N5O4S2Forma y color:SolidPeso molecular:377.4Xeruborbactam isoboxil
CAS:Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.Fórmula:C15H16BFO6Forma y color:SolidPeso molecular:322.093Antifungal agent 38
Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.Fórmula:C8H12N2S2Forma y color:SolidPeso molecular:200.327-Hydroxytropolone
CAS:7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Fórmula:C7H6O3Forma y color:SolidPeso molecular:138.12
