HBV
Los inhibidores del VHB son compuestos diseñados para atacar e inhibir varias etapas del ciclo de vida del virus de la hepatitis B (VHB). Estos inhibidores pueden interferir con la replicación viral, el ensamblaje o la liberación, reduciendo así la carga viral y ayudando a manejar las infecciones crónicas por VHB. La investigación sobre inhibidores del VHB es crucial para desarrollar terapias antivirales efectivas que prevengan enfermedades hepáticas y cánceres asociados con el VHB. En CymitQuimica, ofrecemos una gama de inhibidores del VHB para apoyar su investigación en virología, desarrollo de medicamentos antivirales y gestión de enfermedades infecciosas.
Se han encontrado 176 productos de "HBV"
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BAY39-5493
CAS:<p>BAY39-5493 is a hepatitis B virus inhibitor and possess antiviral activity in vitro and in vivo.</p>Fórmula:C17H15ClFN3O2SForma y color:SolidPeso molecular:379.84LP10
CAS:<p>LP10 is a reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 and a Potent type II inhibitor of Trypanosoma cruzi CYP51.</p>Fórmula:C24H28N4O2Forma y color:SolidPeso molecular:404.5Rolicyprine
CAS:<p>Rolicyprine is an antidepressant.</p>Fórmula:C14H16N2O2Pureza:98%Forma y color:SolidPeso molecular:244.29trans-ccc_R08
CAS:<p>trans-ccc_R08: potent cccDNA inhibitor, IC50 0.08 µM, may help research HBV.</p>Fórmula:C22H19ClO6Forma y color:SolidPeso molecular:414.84HBV-IN-29
CAS:<p>HBV-IN-29 (ex8), a flavone derivative, inhibits cccDNA in HBV research.</p>Fórmula:C22H19ClO6Forma y color:SolidPeso molecular:414.84KKJ00626
CAS:<p>KKJ00626, an inhibitor of HBV virus, inhibits HBV replication in transfected Huh7 cells.</p>Fórmula:C7H8N4SPureza:98%Forma y color:SolidPeso molecular:180.23HBV-IN-19
CAS:<p>HBV-IN19 suppresses HBV, cutting HBsAg output, useful for chronic HBV study.</p>Fórmula:C24H30N2O6Forma y color:SolidPeso molecular:442.5HBV-IN-25
CAS:<p>HBV-IN-25: oral HBV cccDNA reducer, anti-HBeAg, anti-HBV (IC50: 0.58/1.15 μM), soluble (>452 μg/mL), non-toxic.</p>Fórmula:C18H14ClNO4Forma y color:SolidPeso molecular:343.76Selgantolimod
CAS:<p>Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.</p>Fórmula:C14H20FN5OPureza:98%Forma y color:SolidPeso molecular:293.34Inarigivir
CAS:<p>Inarigivir (ORI-9020) is a dinucleotide that can significantly reduce liver HBV DNA.</p>Fórmula:C20H26N7O10PSPureza:98%Forma y color:SolidPeso molecular:587.5Alamifovir
CAS:<p>Alamifovir: HBV-specific antiviral, purine analog prodrug; active against wild-type/lamivudine-resistant HBV; inhibits DNA initiation/packaging.</p>Fórmula:C19H20F6N5O5PSForma y color:SolidPeso molecular:575.42(5S,8R)-HBV-IN-10
CAS:<p>'(5S,8R)-HBV-IN-10 is an EC50 0.1-1 μM HBsAg inhibitor, isomer of compound 6 from patent WO2021204258A1.</p>Fórmula:C23H24FN7OForma y color:SolidPeso molecular:433.48Helioxanthin derivative 5-4-2
CAS:<p>Helioxanthin derivative 5-4-2 （Helioxanthin 5-4-2） is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.</p>Fórmula:C20H13NO5Pureza:99.91% - 99.92%Forma y color:SolidPeso molecular:347.32Fosclevudine alafenamide
CAS:<p>Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent that acts against HBV (EC50: 1.71 μM).</p>Fórmula:C22H29FN3O9PForma y color:SolidPeso molecular:529.45Taribavirin hydrochloride
CAS:<p>Taribavirin HCl: oral drug targeting HCV in liver, spares red blood cells, aims to reduce anemia risk.</p>Fórmula:C8H14ClN5O4Pureza:98%Forma y color:SolidPeso molecular:279.68Helioxanthin 8-1
CAS:<p>Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 μM.</p>Fórmula:C20H12N2O6Pureza:98%Forma y color:SolidPeso molecular:376.32(-)-5′-Noraristeromycin
CAS:<p>(-)-5′-Noraristeromycin is an antiviral agent.</p>Fórmula:C10H13N5O3Forma y color:SolidPeso molecular:251.24RIG-1 modulator 1
CAS:<p>RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.</p>Fórmula:C14H17N5OS2Pureza:98%Forma y color:SolidPeso molecular:335.45BA38017
CAS:<p>BA38017 is a potent assembly modulator of HBV core protein that inhibits the replication of HBV (EC50 = 0.20 μM) [1].</p>Fórmula:C15H11ClFNO3Forma y color:SolidPeso molecular:307.7BA-53038B
CAS:<p>BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).</p>Fórmula:C14H16ClNOForma y color:SolidPeso molecular:249.74Bay 41-4109 (less active enantiomer)
CAS:<p>Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).</p>Fórmula:C18H13ClF3N3O2Pureza:98%Forma y color:SolidPeso molecular:395.76Bentysrepinine
CAS:<p>Bentysrepinine, a novel anti-HBV agent, inhibits DNA-HBV and cccDNA activities for the treatment of hepatitis B virus (HBV)-infected hepatitis.</p>Fórmula:C29H35N3O4Pureza:98%Forma y color:SolidPeso molecular:489.61HBV-IN-10
CAS:<p>HBV-IN-10, an isomer of compound 6, inhibits HBsAg with EC50 between 0.1-1 μM (Patent WO2021204258A1).</p>Fórmula:C23H24FN7OForma y color:SolidPeso molecular:433.48NVP018
CAS:<p>NVP018 (BC 556) inhibits HBV, HCV, HIV-1 replication, barely affects drug transporters, and resists HCV/HIV-1 resistance development.</p>Fórmula:C45H62FN5O11Forma y color:SolidPeso molecular:868DVR-01
CAS:<p>DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions.</p>Fórmula:C20H23ClN2O3SPureza:99.95%Forma y color:SolidPeso molecular:406.93Clevudine triphosphate
CAS:<p>Clevudine triphosphate is a TTP analog that is able to inhibit protein priming independently of the deoxynucleoside triphosphate substrate.</p>Fórmula:C10H16FN2O14P3Pureza:98%Forma y color:SolidPeso molecular:500.16Lagociclovir
CAS:<p>Lagociclovir (MIV-210), a nucleoside analogue antiviral, treats HBV by inhibiting its replication in liver cancer cells.</p>Fórmula:C10H12FN5O3Pureza:99.18% - 99.33%Forma y color:SolidPeso molecular:269.23Bay 41-4109
CAS:<p>BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).</p>Fórmula:C18H13ClF3N3O2Forma y color:SolidPeso molecular:395.76HBV-IN-9
CAS:<p>HBV-IN-9 inhibits HBsAg (IC50: 10 nM) and HBV DNA replication (IC50: 0.15 nM) per WO2018001952A1.</p>Fórmula:C22H24FN7OForma y color:SolidPeso molecular:421.47Taribavirin
CAS:<p>Taribavirin: oral drug targeting HCV in liver, spares RBCs to reduce risk of anemia.</p>Fórmula:C8H13N5O4Pureza:98%Forma y color:SolidPeso molecular:243.22HBV-IN-6
CAS:<p>HBV-IN-6 is a potent inhibitor of HBV (EC50: 44 nM).</p>Fórmula:C23H21ClFN3O5S2Forma y color:SolidPeso molecular:538.01Vidarabine phosphate
CAS:<p>Vidarabine phosphate is an adenosine monophosphate analog.</p>Fórmula:C10H14N5O7PPureza:99.75%Forma y color:White Crystalline PowderPeso molecular:347.22HBV-IN-32
CAS:<p>HBV-IN-32 is a strong cccDNA inhibitor with an IC50 of 0.14 µM against HBsAg, also halting cell growth.</p>Fórmula:C22H19ClO5SForma y color:SolidPeso molecular:430.9L-Fd4A
CAS:<p>L-Fd4A (compound 36) is an adenine derivative with anti-HIV (EC50=1.5μM) and anti-HBV (EC50=1.7μM) effects, low cytotoxicity.</p>Fórmula:C10H10FN5O2Forma y color:SolidPeso molecular:251.22AB-506
CAS:<p>AB-506: Oral HBV replication blocker, targets core protein, hinders pgRNA encapsidation, for CHB study.</p>Fórmula:C21H18ClF2N5O3Forma y color:SolidPeso molecular:461.85cis-ccc_R08
CAS:<p>cis-ccc_R08 infection . cis-ccc_R08 is a cccDNA (covalently closed circular DNA) inhibitor .</p>Fórmula:C22H19ClO6Forma y color:SolidPeso molecular:414.84Besifovir PM
<p>Besifovir PM (LB80331 PM) is an analogue of Besifovir, a novel orally available acyclic nucleotide phosphonate for the treatment of chronic hepatitis B</p>Fórmula:C11H15N5OPureza:98.48% - 99.90%Forma y color:SoildPeso molecular:233.27Isothiafludine
CAS:<p>Isothiafludine is a HBV virus inhibitor that dramatically reduces the HBV DNA level in cells.</p>Fórmula:C18H18FN3OS2Pureza:99.71%Forma y color:SolidPeso molecular:375.48Bersacapavir
CAS:<p>Bersacapavir (JNJ-56136379) is an in vitro modulator of hepatitis B virus capsid assembly that inhibits HBV replication.</p>Fórmula:C16H14F4N4O3SPureza:98.53%Forma y color:SolidPeso molecular:418.37Tivicilovir
CAS:<p>Tivicilovir (AM188) is a hepatitis B virus inhibitor. tiviclovir is a guanine-related acyclic 2'-deoxyguanine analogue with anti-herpesvirus activity.</p>Fórmula:C9H13N5O3Pureza:99.94%Forma y color:SolidPeso molecular:239.23Pradefovir
CAS:<p>Pradefovir (Remofovir) is a prodrug for chronic HBV, converting to PMEA in the liver with a Km of 60 μM and clearance of 359 ml/min.</p>Fórmula:C17H19ClN5O4PPureza:97.50%Forma y color:SolidPeso molecular:423.79HBV-IN-8
CAS:<p>HBV-IN-6 is a potent inhibitor of HBV (EC50: 287.9 nM).</p>Fórmula:C21H25ClFN5O5S2Forma y color:SolidPeso molecular:546.04HBF-0259
CAS:HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.Fórmula:C16H12Cl2FN5Pureza:98.07% - 99.42%Forma y color:SolidPeso molecular:364.2HBV-IN-13
CAS:<p>HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).</p>Fórmula:C22H25NO7Forma y color:SolidPeso molecular:415.44HEC72702
CAS:<p>HEC72702: New HBV capsid inhibitor, from GLS4. No CYP1A2, CYP3A4, CYP2B6 induction at 10μM.</p>Fórmula:C24H26BrFN4O5SForma y color:SolidPeso molecular:581.45HBV-IN-17
CAS:<p>HBV-IN-17 (compound 8) is a potent regulator of HBV capsid assembly (EC50: 511 nM).</p>Fórmula:C17H15F6N5O2Forma y color:SolidPeso molecular:435.32Oxynitidine
CAS:<p>Oxynitidine, an HBV inhibitor (ID50 = 30.8 µg/mL), effectively suppresses HBV DNA replication and may be utilized in viral infection research [1].</p>Fórmula:C21H17NO5Pureza:98%Forma y color:SolidPeso molecular:363.36HBV-IN-41
CAS:<p>HBV-IN-41 (compound 45) is a potent, orally active inhibitor of Hepatitis B Virus (HBV), exhibiting an EC50 value of 0.027μM [1].</p>Fórmula:C18H19ClFN5O3Pureza:98%Forma y color:SolidPeso molecular:407.83Emtricitabine triphosphate tetrasodium salt
CAS:<p>Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside</p>Fórmula:C8H9FN3Na4O12P3SPureza:98%Forma y color:SolidPeso molecular:575.11Tobevibart
CAS:<p>Tobevibart, an IgG1-lambda humanized monoclonal antibody targeting the hepatitis B virus (HBV) surface envelope protein, exhibits antiviral activity [1].</p>Pureza:98%Forma y color:LiquidIR415
CAS:<p>IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx</p>Fórmula:C13H14F2N4SPureza:99.85%Forma y color:SolidPeso molecular:296.34Valtorcitabine dihydrochloride
CAS:<p>Valtorcitabine dihydrochloride, a DNA polymerase inhibitor, is used potentially for the treatment of HBV infection.</p>Fórmula:C14H24Cl2N4O5Forma y color:SolidPeso molecular:399.27Besifovir Dipivoxil maleate
CAS:<p>Besifovir Dipivoxil maleate, an oral HBV prodrug (LB80380), suppresses HBV DNA in naive and lamivudine-resistant CHB cases.</p>Fórmula:C22H34N5O8PPureza:98%Forma y color:SolidPeso molecular:527.51HBV-IN-30
CAS:<p>HBV-IN-30, a flavone derivative, inhibits cccDNA in HBV research.</p>Fórmula:C22H18BrClO6Forma y color:SolidPeso molecular:493.73SHR5133
CAS:<p>SHR5133 is a potent, orally active regulator of HBV capsid assembly that reduces HBV DNA (EC50: 26.6 nM).</p>Fórmula:C19H18F4N6O2Forma y color:SolidPeso molecular:438.38AB-836
CAS:<p>AB-836, an orally active hepatitis B virus (HBV) capsid inhibitor, hampers viral replication by engaging with the HBV core protein.</p>Fórmula:C20H15F3N4O2Forma y color:SolidPeso molecular:400.35Lagociclovir valactate
CAS:<p>Lagociclovir valactate is a prodrug of Lagociclovir . Lagociclovir valactate is an orally active anti- HBV agent [1] .</p>Fórmula:C18H25FN6O6Forma y color:SolidPeso molecular:440.43Linvencorvir
CAS:<p>Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection.</p>Fórmula:C29H35FN6O5SPureza:99.9% - 99.9%Forma y color:SolidPeso molecular:598.69Tenofovir amibufenamide
CAS:<p>Tenofovir amibufenamide (HS-10234) 是一种 Tenofovir 前药，是一种具有口服活性的抗病毒化合物。Tenofovir amibufenamide 对乙型肝炎病毒 (HBV)具有抑制作用，可用于慢性乙型肝炎 (CHB) 研究。</p>Fórmula:C22H31N6O5PPureza:99.19% - 99.87%Forma y color:SolidPeso molecular:490.49HBV-IN-24
<p>HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.</p>Fórmula:C23H27NO6Forma y color:SolidPeso molecular:413.46HBV/HDV-IN-3
CAS:<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Fórmula:C28H27BrF3N5O3Forma y color:SolidPeso molecular:618.44SAG-524
CAS:<p>SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].</p>Fórmula:C30H32ClN5O4SForma y color:SolidPeso molecular:594.12HBV/HDV-IN-2
CAS:<p>HBV/HDV-IN-2 (Compd 143) functions as an inhibitor for HBV, HDV, and PD-1/PD-L1, demonstrating an EC 50 of 35 nM in T cell activation.</p>Fórmula:C38H44ClN7O5Forma y color:SolidPeso molecular:714.25TLR8 agonist 4
<p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>Fórmula:C28H27N5O5SForma y color:SolidPeso molecular:545.61HBV-IN-12
CAS:<p>HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)</p>Fórmula:C23H27NO8Forma y color:SolidPeso molecular:445.46HBV-IN-11
CAS:<p>HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).</p>Fórmula:C21H24ClNO6Forma y color:SolidPeso molecular:421.87HBV-IN-18
<p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>Fórmula:C17H15F6N5O2Forma y color:SolidPeso molecular:435.32HBV-IN-48
CAS:<p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>Fórmula:C22H15F4N3O3Forma y color:SolidPeso molecular:445.37FNC-TP trisodium
<p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>Fórmula:C9H11FN6Na3O13P3Forma y color:SolidPeso molecular:592.11HBV-IN-31
CAS:<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Fórmula:C23H18ClNO6Forma y color:SolidPeso molecular:439.85HBV-IN-20
<p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>Forma y color:SolidALG-000184
CAS:<p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>Fórmula:C23H20FN4Na2O8PForma y color:SolidPeso molecular:576.379HBV-IN-19 TFA
CAS:<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Fórmula:C26H31F3N2O8Forma y color:SolidPeso molecular:556.53HBV-IN-34
CAS:<p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>Fórmula:C21H19F2N7Pureza:98%Forma y color:SolidPeso molecular:407.42Ref: TM-T79469
Producto descatalogadoHBV-IN-38
CAS:<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Fórmula:C18H16F3N5O4S2Pureza:98%Forma y color:SolidPeso molecular:487.48Yhhu6669
CAS:<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Fórmula:C29H28ClFN6O3Pureza:98%Forma y color:SolidPeso molecular:563.02Ref: TM-T78756
Producto descatalogado
