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HBV

HBV

Los inhibidores del VHB son compuestos diseñados para atacar e inhibir varias etapas del ciclo de vida del virus de la hepatitis B (VHB). Estos inhibidores pueden interferir con la replicación viral, el ensamblaje o la liberación, reduciendo así la carga viral y ayudando a manejar las infecciones crónicas por VHB. La investigación sobre inhibidores del VHB es crucial para desarrollar terapias antivirales efectivas que prevengan enfermedades hepáticas y cánceres asociados con el VHB. En CymitQuimica, ofrecemos una gama de inhibidores del VHB para apoyar su investigación en virología, desarrollo de medicamentos antivirales y gestión de enfermedades infecciosas.

Se han encontrado 177 productos de "HBV"

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  • HBV-IN-24


    <p>HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.</p>
    Fórmula:C23H27NO6
    Forma y color:Solid
    Peso molecular:413.46
  • HBV/HDV-IN-3

    CAS:
    <p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>
    Fórmula:C28H27BrF3N5O3
    Forma y color:Solid
    Peso molecular:618.44
  • SAG-524

    CAS:
    <p>SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].</p>
    Fórmula:C30H32ClN5O4S
    Forma y color:Solid
    Peso molecular:594.12
  • HBV/HDV-IN-2

    CAS:
    <p>HBV/HDV-IN-2 (Compd 143) functions as an inhibitor for HBV, HDV, and PD-1/PD-L1, demonstrating an EC 50 of 35 nM in T cell activation.</p>
    Fórmula:C38H44ClN7O5
    Forma y color:Solid
    Peso molecular:714.25
  • TLR8 agonist 4


    <p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>
    Fórmula:C28H27N5O5S
    Forma y color:Solid
    Peso molecular:545.61
  • HBV-IN-12

    CAS:
    <p>HBV-IN-12: strong HBsAg &amp; HBV DNA inhibitor; EC50 0.001-0.05 μM &amp; 0.001-0.02 μM respectively. (WO2021204252A1)</p>
    Fórmula:C23H27NO8
    Forma y color:Solid
    Peso molecular:445.46
  • HBV-IN-11

    CAS:
    <p>HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).</p>
    Fórmula:C21H24ClNO6
    Forma y color:Solid
    Peso molecular:421.87
  • HBV-IN-18


    <p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>
    Fórmula:C17H15F6N5O2
    Forma y color:Solid
    Peso molecular:435.32
  • HBV-IN-48

    CAS:
    <p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>
    Fórmula:C22H15F4N3O3
    Forma y color:Solid
    Peso molecular:445.37
  • FNC-TP trisodium


    <p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>
    Fórmula:C9H11FN6Na3O13P3
    Forma y color:Solid
    Peso molecular:592.11
  • HBV-IN-31

    CAS:
    <p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>
    Fórmula:C23H18ClNO6
    Forma y color:Solid
    Peso molecular:439.85
  • HBV-IN-20


    <p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>
    Forma y color:Solid
  • ALG-000184

    CAS:
    <p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>
    Fórmula:C23H20FN4Na2O8P
    Forma y color:Solid
    Peso molecular:576.379
  • HBV-IN-19 TFA

    CAS:
    <p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>
    Fórmula:C26H31F3N2O8
    Forma y color:Solid
    Peso molecular:556.53
  • HBV-IN-34

    CAS:
    <p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>
    Fórmula:C21H19F2N7
    Pureza:98%
    Forma y color:Solid
    Peso molecular:407.42

    Ref: TM-T79469

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  • HBV-IN-38

    CAS:
    <p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>
    Fórmula:C18H16F3N5O4S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:487.48

    Ref: TM-T79879

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  • Yhhu6669

    CAS:
    <p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>
    Fórmula:C29H28ClFN6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:563.02

    Ref: TM-T78756

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