HBV
Los inhibidores del VHB son compuestos diseñados para atacar e inhibir varias etapas del ciclo de vida del virus de la hepatitis B (VHB). Estos inhibidores pueden interferir con la replicación viral, el ensamblaje o la liberación, reduciendo así la carga viral y ayudando a manejar las infecciones crónicas por VHB. La investigación sobre inhibidores del VHB es crucial para desarrollar terapias antivirales efectivas que prevengan enfermedades hepáticas y cánceres asociados con el VHB. En CymitQuimica, ofrecemos una gama de inhibidores del VHB para apoyar su investigación en virología, desarrollo de medicamentos antivirales y gestión de enfermedades infecciosas.
Se han encontrado 170 productos para "HBV".
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Emtricitabine triphosphate tetrasodium salt
CAS:Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleosideFórmula:C8H9FN3Na4O12P3SPureza:98%Forma y color:SolidPeso molecular:575.11Carbovir
CAS:Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.Fórmula:C11H13N5O2Forma y color:SolidPeso molecular:247.25Tobevibart
CAS:Tobevibart, an IgG1-lambda humanized monoclonal antibody targeting the hepatitis B virus (HBV) surface envelope protein, exhibits antiviral activity [1].Pureza:98%Forma y color:Liquident-Entecavir
CAS:Ent-Entecavir, an enantiomeric impurity of Entecavir (an oral HBV drug), inhibits HBV replication as a reverse transcriptase inhibitor.Fórmula:C12H15N5O3Forma y color:SolidPeso molecular:277.28HBF-0259
CAS:HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.Fórmula:C16H12Cl2FN5Pureza:98.07% - 99.42%Forma y color:White SolidPeso molecular:364.2Ref: TM-T27527
2mg34,00€1mL*10mM (DMSO)34,00€10mg46,00€5mg49,00€25mg77,00€50mg103,00€100mg155,00€200mg349,00€AB-836
CAS:AB-836, an orally active hepatitis B virus (HBV) capsid inhibitor, hampers viral replication by engaging with the HBV core protein.Fórmula:C20H15F3N4O2Forma y color:SolidPeso molecular:400.35Helioxanthin 8-1
CAS:Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 μM.Fórmula:C20H12N2O6Pureza:98%Forma y color:SolidPeso molecular:376.32HBV-IN-8
CAS:HBV-IN-6 is a potent inhibitor of HBV (EC50: 287.9 nM).Fórmula:C21H25ClFN5O5S2Forma y color:SolidPeso molecular:546.04HBV-IN-13
CAS:HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).Fórmula:C22H25NO7Forma y color:SolidPeso molecular:415.44Besifovir Dipivoxil maleate
CAS:Besifovir Dipivoxil maleate, an oral HBV prodrug (LB80380), suppresses HBV DNA in naive and lamivudine-resistant CHB cases.Fórmula:C22H34N5O8PPureza:98%Forma y color:SolidPeso molecular:527.51IR415
CAS:IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBxFórmula:C13H14F2N4SPureza:99.85%Forma y color:White SolidPeso molecular:296.34Ref: TM-T11669
5mg43,00€1mL*10mM (DMSO)47,00€10mg71,00€25mg128,00€50mg215,00€100mg318,00€200mg444,00€ZINC20451377
CAS:ZINC20451377 is a small molecule compound that binds with high affinity to the hepatitis B surface antigen (HBsAg), with a dissociation constant (Kd) of 65.3 nM. It reduces HBsAg levels and HBV particle secretion in HBV cell culture models.Fórmula:C32H38N4O3Forma y color:SolidPeso molecular:526.67HBV-IN-30
CAS:HBV-IN-30, a flavone derivative, inhibits cccDNA in HBV research.Fórmula:C22H18BrClO6Forma y color:SolidPeso molecular:493.73SHR5133
CAS:SHR5133 is a potent, orally active regulator of HBV capsid assembly that reduces HBV DNA (EC50: 26.6 nM).Fórmula:C19H18F4N6O2Forma y color:SolidPeso molecular:438.38Tenofovir amibufenamide
CAS:Tenofovir amibufenamide (HS-10234) 是一种 Tenofovir 前药，是一种具有口服活性的抗病毒化合物。Tenofovir amibufenamide 对乙型肝炎病毒 (HBV)具有抑制作用，可用于慢性乙型肝炎 (CHB) 研究。Fórmula:C22H31N6O5PPureza:99.19% - 99.87%Forma y color:SolidPeso molecular:490.49CCC-0975
CAS:CCC-0975 is an inhibitor of hepatitis B virus (HBV) with an EC50 of 10 μM. It interferes with the conversion of relaxed circular DNA (rcDNA) to covalently closed circular DNA (cccDNA) and reduces cccDNA and its precursor deproteinized rcDNA (DP-rcDNA), without promoting their degradation inside cells. CCC-0975 holds potential for chronic hepatitis B research.Fórmula:C21H17ClF3N3O3SForma y color:SolidPeso molecular:483.89HBV/HDV-IN-3
CAS:HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .Fórmula:C28H27BrF3N5O3Forma y color:SolidPeso molecular:618.44SAG-524
CAS:SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].Fórmula:C30H32ClN5O4SForma y color:SolidPeso molecular:594.12HBV/HDV-IN-2
CAS:HBV/HDV-IN-2 (Compd 143) functions as an inhibitor for HBV, HDV, and PD-1/PD-L1, demonstrating an EC 50 of 35 nM in T cell activation.Fórmula:C38H44ClN7O5Forma y color:SolidPeso molecular:714.25HBV-IN-18
HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).Fórmula:C17H15F6N5O2Forma y color:SolidPeso molecular:435.32
