mTOR
Los inhibidores de mTOR son compuestos que inhiben la actividad de la Proteína diana de la rapamicina en mamíferos (mTOR), un regulador central del crecimiento celular, la proliferación, el metabolismo y la supervivencia. La vía de mTOR se altera con frecuencia en el cáncer y otras enfermedades, lo que convierte a mTOR en un objetivo crítico para la intervención terapéutica. Los inhibidores de mTOR se utilizan ampliamente en la investigación relacionada con el cáncer, el envejecimiento y los trastornos metabólicos. En CymitQuimica, ofrecemos una variedad de inhibidores de mTOR para apoyar su investigación en transducción de señales, oncología y desarrollo terapéutico.
Se han encontrado 144 productos de "mTOR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ETP-46464
CAS:<p>ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).</p>Fórmula:C30H22N4O2Pureza:97.76%Forma y color:SolidPeso molecular:470.52BGT226 maleate
CAS:<p>BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .</p>Fórmula:C28H25F3N6O2·C4H4O4Pureza:97.75% - 98.78%Forma y color:SolidPeso molecular:650.6NVP-BBD130
CAS:<p>NVP-BBD130 is a stable, ATP-competitive, potent, orally active inhibitor of PI3K and mTOR.</p>Fórmula:C28H21N5OForma y color:SolidPeso molecular:443.5PI3K/mTOR Inhibitor-13
CAS:<p>PI3K/mTOR Inhibitor-13, an oral dual blocker of PI3K and mTOR, may treat sexual diseases, solid tumors, and IPF.</p>Fórmula:C20H13F2N5O3SForma y color:SolidPeso molecular:441.41PI3Ka-IN-5
CAS:<p>PI3Ka-IN-5 is a potent PI3Kα/mTOR inhibitor, with an IC 50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer .</p>Fórmula:C30H35N9O5Forma y color:SolidPeso molecular:601.66PKI-179
CAS:<p>PKI-179: Dual PI3K/mTOR inhibitor, orally active, IC50s: 0.42-77 nM, targets E545K and H1047R, antitumor in vivo.</p>Fórmula:C25H28N8O3Forma y color:SolidPeso molecular:488.54PKI-179 hydrochloride
CAS:<p>PKI-179: oral PI3K/mTOR inhibitor; IC50: PI3Kα/β/δ/γ (8-74 nM), PI3Kα mutants (11-14 nM), mTOR (0.42 nM); selective; inhibits cancer cell growth.</p>Fórmula:C25H29ClN8O3Forma y color:SolidPeso molecular:525PI3K/mTOR Inhibitor-8
CAS:<p>PI3K/mTOR Inhibitor-8: Dual PI3Kα (IC50: 0.46 nM) & mTOR (IC50: 12 nM) inhibitor; blocks G1/S phase & induces apoptosis in HCT-116 cells.</p>Fórmula:C23H22N8O4SForma y color:SolidPeso molecular:506.54eCF-309
CAS:<p>eCF-309 is a potent mTOR inhibitor with IC50 value of 15 nM.</p>Fórmula:C18H21N7O3Forma y color:SolidPeso molecular:383.4PI3K/mTOR Inhibitor-4
CAS:<p>Oral PI3K/mTOR Inhibitor-4 targets PI3Kα, γ, δ, mTOR; IC50s: 0.63, 22, 9.2, 13.85 nM. Used in cancer research.</p>Fórmula:C27H22FN3O6SForma y color:SolidPeso molecular:535.54PI3-Kinase α Inhibitor 2
CAS:<p>Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce the second messengers PtdIns-(3,4)-P2 and</p>Fórmula:C16H15N3O2SForma y color:SolidPeso molecular:313.37OXA-01
CAS:<p>OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC 50 values of 29 nM and 7 nM, respectively [1]. OXA-01 demonstrates broad anti-tumor activity.</p>Fórmula:C21H20ClN5O2Forma y color:SolidPeso molecular:409.87FT-1518
CAS:<p>FT-1518 is an orally available, selective and potent mTORC1 and mTORC2 inhibitor with anticancer and antitumor activity for cancer research.</p>Fórmula:C20H26N8OPureza:98.34% - 98.80%Forma y color:SolidPeso molecular:394.47P-2281
CAS:<p>P-2281 is an mTOR inhibitor with anticancer and anti-inflammatory properties.P-2281 inhibits dextran sulfate sodium (DSS)-induced colitis by suppressing T-cell</p>Fórmula:C9H8ClN3OPureza:99.95%Forma y color:SolidPeso molecular:209.63mTOR inhibitor-2
CAS:<p>mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).</p>Fórmula:C23H21N7OPureza:98%Forma y color:SolidPeso molecular:411.46PI3K/mTOR Inhibitor-2
CAS:<p>Potent PI3K/mTOR Inhibitor-2 targets PI3Kα/β/δ/γ & mTOR (IC50: 3.4, 34, 16,1, 4.7 nM); exhibits antitumor effects.</p>Fórmula:C20H13ClF2N4O4SPureza:96.16%Forma y color:SolidPeso molecular:478.86PI3K/mTOR Inhibitor-9
CAS:<p>PI3K/mTOR Inhibitor-9 acts on mTOR (38 nM IC50) and PI3Kα/γ (6.6 nM IC50), PI3Kδ (0.8 nM IC50).</p>Fórmula:C23H27N7O2Forma y color:SolidPeso molecular:433.51PP30
CAS:<p>PP30 is an inhibitor of mTORC1 and mTORC2. It is selective within the PI3K family, inhibiting other PI3Ks only at high concentrations.</p>Fórmula:C18H19N7OSPureza:98%Forma y color:SolidPeso molecular:381.45PI3K/mTOR Inhibitor-3
CAS:<p>PI3K/mTOR Inhibitor-3, a potent dual-action anti-cancer imidazoline, targets PI3K and mTOR.</p>Fórmula:C22H23N5OForma y color:SolidPeso molecular:373.45PI-540
CAS:<p>PI-540 is a potent and selective inhibitor of class 1A phosphatidylinositide 3-kinases (PI3K).</p>Fórmula:C22H27N5O2SForma y color:SolidPeso molecular:425.55
