Compuestos policíclicos

Stability Hygroscopic
Applications 2-AMINO-1,2,3,4-TETRAHYDROISOQUINOLINE-1,3-DIONE (cas# 22177-46-4) is a useful research chemical.

Applications N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide is used in synthesis of an antitumor agent, neratinib (N390090).
References Zhang, P., et al.: Zhongguo Yaowu Huaxue Zazhi, 18, 355 (2008);

Applications 2,2'-Bipyridine-4,4'-dicarboxamide

Applications 2,6-Diazaspiro[3.3]heptane-2-carboxylic Acid tert-Butyl Ester Hemioxylate is preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for treatment of diseases.
References Katamreddy, S. R., et al.: PCT Int. Appl. (2020), WO 2020140055 A1

Applications Triclocarban Related Compound A (cas# 1219-99-4) is a useful research chemical.

Applications 2,2'-Bipyridyl-d8 was a useful compound in the NMR study of soft porous nanocrystal and a bulk crystal.
References Hijikata, Y., et al.: Chem. Commun. (Cambridge, UK), 47, 7632 (2011)

Applications 2-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 79999-39-6) is a compound useful in organic synthesis.

Stability Moisture Sensitive
Applications 1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-sulfonyl chloride (cas# 1240529-56-9) is a useful research chemical.

Applications 4-Acetoxyindole is a useful intermediate for organic synthesis of Psilocine and Psilocine analogs.
References Julia, M., et al.: Chimica Therapeutica, 5, 279 (1970); Repke, D. B., et al.: J. Heterocycl. Chem., 14, 71 (1977)

Stability Moisture Sensitive
Applications Isoquinoline-5-sulfonyl Chloride, Hydrochloride (cas# 105627-79-0) is a compound useful in organic synthesis.

Applications 3-Aminoquinoline-2-carboxylic acid (cas# 887245-74-1) is a useful research chemical.

Applications 7-Aminoindole

Applications 1H-Indole-d5-3-acetamide is the isotope labelled analogue of Indole-3-acetamide, a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants.
References Mano, Y., et al.: J. Exp. Bot., 61, 25 (2010);

Applications 9-oxo-9H-Thioxanthene-4-carboxylic acid (cas# 51762-56-2) is a useful research chemical.

Applications 5-Hydroxyquinoline-3-carboxylic acid (cas# 911108-90-2) is a useful research chemical.

Applications 4,8-DICHLOROQUINOLINE (cas# 21617-12-9) is a useful research chemical.

Applications 2-Oxa-7-azaspiro[3.5]nonane is an intermediate used to prepare benzothienoazepine derivatives as potent respiratory syncytial virus RNA polymerase inhibitors. It is also used to prepare 1,7-Diazacarbazole derivatives as inhibitors of checkpoint kinase 1.
References Xiong, H., et al.: Bioorg. Med. Chem. Lett., 23, 6789 (2013); Gazzard, L., et al.: J. Med. Chem., 58, 5053 (2015)

Applications 3-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-3,4-dihydro-5H-imidazo[2,1-i]purine-5-thione is used in the synthesis of azidoetheno analogs of deoxyadenosine as nucleotide photo-affinity probes.
References Flaherty, D. et al.: Nucleos. Nucleot., 14, 65 (1995);

Stability Hygrscopic
Applications 2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt

Applications Methyl quinoline-4-carboxylate (cas# 21233-61-4) is a useful research chemical.

Applications Ethyl 4,6,8-trichloroquinoline-3-carboxylate

Applications Can be used in the preparation of serotoninergic S2 antagonists.
References Andersen, K. et al.: J. Med. Chem. 39, 3723(1996); Perregaard, J. et al.: J. Med. Chem. 35, 1092(1992)

Applications A 6-substituted 8-quinolinecarboxylic acid as antimicrobial and genotoxic agent.
References Weyer, R., et al.: Arzneim.-Forsch., 24, 269 (1974),

Applications Quinoline-3-sulfonyl Chloride (cas# 159182-40-8) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 1H-Indole-3-carboxylic acid hydrazide

Applications 6-Bromo-2-(4-bromophenyl)indole (cas# 28718-96-9) is a compound useful in organic synthesis.

Applications 2-(1-Cyanoethyl)indole-13C215N is an isotope labelled intermediate for the synthesis of pharmaceutical actives, intermediates and fine chemicals.
References Pezzuto, J.M., et al.: Biochem., 20, 298 (1981), Takeda, K., et al.: Chem. Pharm. Bull., 29, 1280 (1981),

Applications 2-Deuteroindole is a useful reagent in the preparation of deuterated labeled indoles.
References Lautie, M. F., et al.: J. Label. Compd. Radiopharm., 16, 735 (1979); Ibaceta-Lizana, J. S. L., et al.: J. Chem. Soc. Perkin Trans 2., 9, 1221 (1987)

Applications 5-Fluoro-8-nitroquinoline (cas# 152167-85-6) is a useful research chemical.

Applications tert-butyl 7-hydroxy-3,4-dihydroisoquinoline-2(1h)-carboxylate (cas# 188576-49-0) is a useful research chemical.

Applications 6-Fluoroquinolin-2(1H)-one

Applications 7-Deazapurine (cas# 18549-65-0) is a compound useful in organic synthesis.

Applications 2,2'-(2-Hydroxypropane-1,3-diyl)bis(1H-isoindole-1,3(2H)-dione) is a reagent used for the preparation of functionalized tripodal ligands and their metal complexes for imaging applications.
References Dunn, T.J., et al.: PCT Int. Appl., 1995:494561 (1995)

Applications (Z)-9-(2-Propen-1-ylidene)-2-(trifluoromethyl)-9H-thioxanthene is an intermediate used in the synthesis of (E/Z)-Flupentixol-d4 Dihydrochloride (F597982), which is a neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.
References Nielsen, et al.: Acta Pharmacol. Toxicol., 32, 363 (1973), Post, M.L., et al.: Nature, 256, 342 (1975), Peuch, et al.: Neuropharmacology, 20, 1279 (1981),

Applications Indolyl-3-(ethyl-β-bromide) (cas# 3389-21-7) is a compound useful in organic synthesis.

Applications 1,4-Diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct (cas# 119752-83-9) is a useful research chemical.

Applications 4,7-Dimethylquinolin-2(1H)-one is a reagent in the preparartion of citralidene hydrazido quinolinones which has antibacterial activity.
References Piste, P. B., et al.: J. Chem. Biol. Phy. Sci., 3, 1746 (2013);

Applications N’,N’-Dimethylindole-2-carboxamide (cas# 7511-14-0) is a compound useful in organic synthesis.

Applications 1,2,3,4-Tetrahydroisoquinoline-6,7-diol hydrobromide (cas# 52768-23-7) is a useful research chemical.

Applications 2-Azabicyclo[2.2.2]octan-3-one (cas# 3306-69-2) is a useful research chemical.

Applications 5-Nitro-1H-quinolin-2-one is used in the synthetic preparation of novel antileishmanial agents for Leishmania donovani promastigotes.
References Paloque, L., et al.: Europ. J. Med. Chem., 54, 75 (2012);

Applications 8-Hydroxyquinoline (cas# 148-24-3) is a compound useful in organic synthesis.

Applications 5-Aminotricyclo[3.3.1.13,7]decane-1,3-diol is an intermediate used in the synthesis of Hydroxy Vildagliptin (V305035), which is an impurity of Vildagliptin (V305000). Vildagliptin is a DPP-​4 enzyme inhibitor, has anti-oxidant properties and used as an apoptotic agent on pancreatic cancer . Vildagliptin is used to treat type 2 diabetes mellitus (T2DM) and improve the endothelial function of patients.
References Amritha, C.A., et al.: J. Clin. Diagn. Res., 9, FC14 (2015); Cosenso-Martin, L.N., et al.: Diabetol. Metab. Syndr., 7, 70/1 (2015)