Otros inhibidores

<p>KHK-IN-4 (compound 14) is a potent inhibitor of ketohexokinase (KHK), applicable in the research of fructose metabolism diseases [1].</p>

<p>M 79193 induces total hepatic microsomal cytochrome P-450.</p>

<p>Phthalimide, N-(5-(4-amino-2-ethoxyphenoxy)pentyl)- is a bioactive chemical.</p>

<p>Isobiflorin is a useful organic compound for research related to life sciences. The catalog number is T125766 and the CAS number is 152041-16-2.</p>

<p>L 1215 is a bioactive chemical.</p>

<p>Pyrazosulfuron-ethyl a sulfonylurea herbicide for the control of broadleaf weeds, grasses and sedges in rice, acts by inhibiting ALS (acetolactate synthase).</p>

<p>FITC-labeled ODN 2088 (sodium) serves as a potent inhibitor of TLR3, TLR7, and TLR9, and is utilized to assess CpG ODN cellular uptake and localization</p>

<p>Epicatechin (Epicatechol; Acacatechin; Kakaol) is a useful organic compound for research related to life sciences and the catalog number is T131567.</p>

<p>3,5-Di-O-galloylshikimic acid is a useful organic compound for research related to life sciences.</p>

<p>DNA polymerase-IN-4 (Compd 5c), a coumarin derivative, exhibits antiretroviral activity, achieving an IC50 of 134.22 μM [1].</p>

<p>Alterporriol C is a biochemical.</p>

<p>6,6''-Bigenkwanin is a useful organic compound for research related to life sciences. The catalog number is T125633 and the CAS number is 166824-22-2.</p>

<p>Barbaloin-related compound A is a useful organic compound for research related to life sciences and the catalog number is T124815.</p>

<p>Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.</p>

<p>Mal-amide-PEG2-oxyamineBoc is a PEG-based linker with Boc-protected oxyamine for synthesizing PROTACs.</p>

<p>Methyl 7(Z)-hexadecenoate, a sex pheromone of Trogoderma glabrum, elicits attraction and sexually excitatory responses in male Trogoderma glabrum [1].</p>

<p>N-Tetracosanoyltyramine is a useful organic compound for research related to life sciences and the catalog number is T126368.</p>

<p>Palatiferin A is a useful organic compound for research related to life sciences. The catalog number is T125987 and the CAS number is 1361308-20-4.</p>

<p>AKP-11 is a sphingosine-1-phosphate receptor 1 (S1P1) agonist with an EC50 of 0.047 μM for [35S]GTPγS binding to CHO-K1 cell membranes expressing human S1P1. It reduces S1P1 surface expression and enhances Akt and ERK phosphorylation in CHO cells with S1P1-HA at a 100 nM concentration. At doses of 1.3 and 3 mg/kg, AKP-11 lowers IFN-γ and IL-17 protein levels in the spinal cord and mitigates disease severity in a rat experimental autoimmune encephalomyelitis (EAE) model. Additionally, it decreases peripheral total lymphocyte and specific T cell subsets (CD4+, CD8+, and CD26L+ T cells) counts in both EAE rats and healthy controls at a 1.3 mg/kg dosage.</p>

<p>CHO-CH2-PEG1-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>Bacitracin, a cyclic dipeptide antibiotic from Bacillus, needs Cu2+, Ni2+, Co2+, Zn2+, Mn2+ for efficacy.</p>

<p>BW 633C is a octapeptide with aminoalcohol (AA) linkage between Leu &amp; Val.</p>

<p>Propyl-3-tert-butylphenoxyacetate is a Growth Regulator / Fertilizer.</p>

<p>3,3'-((2-Cl-phenyl)methylene)bis(4-OH-2H-chromen-2-one): ENPP1 inhibitor, Ki=50μM; urease inhibitor, IC50=84.53μM.</p>

<p>m-PEG20-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>Lambertine is a bioactive chemical.</p>

<p>Yinxiancaoside C is a useful organic compound for research related to life sciences and the catalog number is T126317.</p>

<p>Imiclopazine is a phenothiazine derivative with good sedative, analgesic, antiaggressive and antiemetic effects.</p>

<p>Chloromonilinic acid B is a useful organic compound for research related to life sciences. The catalog number is T126197 and the CAS number is 121927-79-5.</p>

<p>Panamycin 607 is a useful organic compound for research related to life sciences and the catalog number is T126536.</p>

<p>Endosidin1 is a natural vesicle trafficking inhibitor.</p>

<p>Linuron-trifluralin mixt is a herbicide.</p>

<p>4-(Dimethylamino)-1-methylpyridinium: a pyridinium salt with anticholinesterase, IC50 of 17 μM in ChoK, and anti-HT-29 cancer activity, IC50 of 2 μM.</p>

<p>Cytidine-5’-O-(2-thiodiphosphate) (CDP-β-S), a non-hydrolyzable derivative of CDP exhibiting antioxidant activity, effectively scavenges free radicals as</p>

<p>Chemodosimeter 1: selective sensor for ATP-triggered phosphate ion production in SF9 cells, first to track PI via half-channel closure.</p>

<p>PI5P4K-β-IN-2 (compound d5) is a potent inhibitor of the PI5P4K-β enzyme, demonstrating an IC50 value of 0.35 μM and exhibiting antitumor activity.</p>

<p>AG 85-12 is a mimic of the C-terminal portion of angiotensin I.</p>

<p>Albireodelphin A is a biochemical.</p>

<p>Tumulosic acid is a natural product for research related to life sciences. The catalog number is T41243 and the CAS number is 508-24-7.</p>

<p>Jasminoside N is a useful organic compound for research related to life sciences. The catalog number is T126179 and the CAS number is 1231710-13-6.</p>

<p>Mito-SilylDCA, a mitochondrial-targeted pyruvate dehydrogenase kinase (PDK1) inhibitor, possesses a thiamine pyrophosphate (TPP) moiety for PDK1 targeting</p>

<p>Isodomoic acid G is a useful organic compound for research related to life sciences and the catalog number is T125500.</p>

<p>Enteropeptidase substrate with AFC; cleaves DDDDK sequence; activates trypsinogen; measured by AFC fluorescence (Ex/Em 380/500 nm).</p>

<p>Levopimaric acid: plant-based diterpene with anticancer, antioxidant, antibacterial, and heart benefits. Promotes cancer cell death.</p>

<p>Lorajmine hydrochloride is used as a Cardiac Depressant (Antiarrhythmic).</p>

<p>Compound 0449-0045 is a useful organic compound for research related to life sciences and the catalog number is T131673.</p>

<p>NCT 501 hydrochloride: potent ALDH1A1 inhibitor, &gt;1000x selectivity vs other ALDHs/GPCRs, IC50=40nM, BBB-permeable.</p>

<p>Cioteronel: antineoplastic, antiandrogenic, inhibits RNA synthesis, blocks DHT binding, no estrogen/progesterone receptor impact.</p>

<p>Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride is a bioactive chemical.</p>

<p>Artemorin is a useful organic compound for research related to life sciences. The catalog number is T124480 and the CAS number is 64845-92-7.</p>

<p>Angeloylgomisin M1 is a useful organic compound for research related to life sciences. The catalog number is T123871 and the CAS number is 95152-96-8.</p>

<p>BMS-1166 is a PD-1/PD-L1 inhibitor with a PROTAC linker, used in PROTAC PD-1/PD-L1 degrader-1 with an IC50 of 39.2 nM.</p>

<p>LXY6090 suppresses HIF-1α in breast cancer, showing anticancer effects in vivo on MX-1 tumors in mice.</p>

<p>Tafluposide is a DNA topoisomerase inhibitor with anti-tumor activity.</p>

<p>Plipastatin A1, a lipopeptide isolated from B.</p>

<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>

<p>L 702157 is a bioactive chemical.</p>

<p>IMCTA-C14, a detergent and derivative of the microbial metabolite 4-trehalosamine, exhibits a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-</p>

<p>Acid-PEG8-S-S-PEG8-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>Compound N050-0021 is a useful organic compound for research related to life sciences and the catalog number is T131247.</p>

<p>Leucoquinizarin is a fluorimetric reagent.</p>

<p>Gnemontanin F is a useful organic compound for research related to life sciences and the catalog number is T125311.</p>

<p>3-Hydroxy tridecanoic acid is a saturated fatty acid found in the LPS of bacteria and can be used as an internal standard for the detection of microbial marker.</p>

<p>Psychotrine is a useful organic compound for research related to life sciences. The catalog number is T124259 and the CAS number is 7633-29-6.</p>

<p>(R)-8-Azido-2-(Fmoc-amino)octanoic acid, a non-cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs).</p>

<p>2-Deoxyribose 5-phosphate disodium acts as a substrate for the enzyme 2-deoxyribose-5-phosphate aldolase (DERA), which is categorized under class I aldolases. DERA efficiently facilitates the reversible aldol condensation reaction independently, without the need for any cofactors [1].</p>

<p>Hispanolone is a useful organic compound for research related to life sciences and the catalog number is T131449.</p>

<p>Methyl nomilinate, derived from citrus, can modulate cell cycle regulators, thereby inducing cytotoxicity in human colon cancer (SW480) cells in vitro.</p>

<p>Steroid sulfatase-IN-5 (compound 10b), an inhibitor of steroid sulfatase (STS) with an IC50 of 0.32 nM, effectively suppresses T-47D breast cancer cell</p>

<p>LysoFP-NH2: CO-detecting lysosomal fluorescent probe, turns on with CO, reacts from lysoFP-NO2, excites at 440 nm, emits at 528 nm.</p>

<p>N, N-Diethyl-p-toluamide is an agent of mosquito repellent.</p>

<p>Antiparasitic Agent-19 (Compound 40) is a broad-spectrum antiparasitic with minimal toxicity to Trypanosoma brucei, Leishmania infantum, and Trypanosoma cruzi [</p>

<p>2-Azabicyclo(3.2.1)octane, 3,4,4-trimethyl- is a bioactive chemical.</p>

<p>Cordatin is a useful organic compound for research related to life sciences. The catalog number is T126401 and the CAS number is 110382-43-9.</p>

<p>Ent-Norsecurinine is a useful organic compound for research related to life sciences and the catalog number is T131499.</p>

<p>Glutathione S-Transferase (GST) π-class inhibitor acts to inhibit a specific class within the GST enzyme family, targeting the π variant. This compound selectively blocks the activity of this enzyme, which plays a critical role in the detoxification of compounds by catalyzing their conjugation with glutathione.</p>

<p>Isobutyryl-CoA: a short-chain acyl CoA, valine catabolism substrate, and precursor to isobutyryl-L-carnitine.</p>

<p>Compound 0080-0034 is a useful organic compound for research related to life sciences and the catalog number is T131698.</p>

<p>L 650719 is a bioactive chemical.</p>

<p>Peperomin B is a useful organic compound for research related to life sciences. The catalog number is T126098 and the CAS number is 129011-96-7.</p>

<p>C17 Ceramide, synthetic with C17:0 fatty acid, marks arylsulfatase A/B activity in metachromatic leukodystrophy therapy.</p>

<p>Lankanolide is the aglycon of lankamycin.</p>

<p>24-Methylenecycloartane-3β,26-diol is a natural product and can be used as a standard reference.</p>

<p>BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.</p>

<p>Extensumside H is a useful organic compound for research related to life sciences. The catalog number is T125381 and the CAS number is 2079912-14-2.</p>

<p>H-Asn-Arg-OH is used for the solid-phase peptide synthesis.</p>

<p>GGA, an isoprenoid anticancer agent from S. chinensis, induces apoptosis in cancerous hepatocytes, not healthy ones, affecting mitochondria and enzymes.</p>

<p>NKG2D-IN-2 (compound 47) is an inhibitor of the natural killer group 2D receptor (NKG2D), demonstrating half-maximal inhibitory concentrations (IC50s) of 0.1 µM</p>

<p>CBGAQ, an analytical reference standard, is an oxidative quinone derivative of cannabigerolic acid (CBGA), designed for research and forensic applications.</p>

<p>TL13-149 is an AC220-based FLT3 degrader.</p>

<p>RIP2 Kinase Inhibitor 4, a selective RIPK2 PROTAC, degrades RIPK2 (pIC50=8), inhibits TNF-α release.</p>

<p>5-O-Coumaroylquinic acid (3-O-Coumaroylquinic acid), exhibits significant inhibition of PTP1B and a concentration-dependent inhibitory effect on α-glucosidase, thereby demonstrating anti-hyperglycemic properties. Additionally, this compound enhances glucose uptake and inhibits PTP1B in vitro, emphasizing its potential therapeutic applications in glucose regulation.</p>

<p>icFSP1, an inhibitor of ferroptosis suppressor protein 1 (FSP1), promotes condensation and phase separation of FSP1 in cellular environments at 2.5 µM</p>

<p>2H-1-Benzopyran-5-ol is a natural product that can be used as a reference standard.</p>

<p>Q151 is an IMPDH inhibitor. It also is a potential antituberculosis agent.</p>

<p>Latanoprost amide is a derivative of latanoprost.</p>

<p>Salverine is a bioactive chemical.</p>

<p>Baogongteng A is a useful organic compound for research related to life sciences and the catalog number is T124289.</p>

<p>5,7,4'-Trihydroxy-3,8,3'-trimethoxyflavone is a natural product and can be used as a standard reference.</p>

<p>Marrubic Acid is a useful organic compound for research related to life sciences and the catalog number is T131400.</p>