Otros inhibidores

<p>1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzodioxin (PCDD) congener. At the highest dose (10,000 μg/kg), it can cause hepatic pallor (fatty liver), gastrointestinal bleeding, and early mortality in H/W and A strain rats. Additionally, 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin induces liver sinusoidal dilatation and can lead to severe purpura in B strain rats.</p>

Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker commonly employed for synthesizing PROTACs[1].

<p>The synthetic compound me4 Peptide, designed from the microexon me4 sequence of the neuronal CPEB4 protein, can inhibit the aggregation of CPEB4 and is applicable in research on autism spectrum disorder-related conditions.</p>

Add 4743 is an analog of sitoglitazone, which is also a fat-forming agent.

<p>Berninamycin C is a useful organic compound for research related to life sciences. The catalog number is T125688 and the CAS number is 161263-49-6.</p>

<p>OVA-PEG-Cy3 is a conjugate of OVA-PEG labeled with Cy3. The Cy3 fluorophore is widely used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry, with its maximum emission wavelength approximately at 562-570 nm. Ovalbumins (OVA) are the primary proteins found in egg whites, known for their diverse biological activities, including anticancer, antihypertensive, antibacterial, antioxidant, and immunoregulatory effects. Ovalbumins are the most abundant proteins synthesized in oviducts treated with progesterone or estrogen and are commonly used as markers to study hormone regulation of gene expression in tissues.</p>

<p>Symplocoside is a natural product that can be used as a reference standard. The CAS number of Symplocoside is 76502-76-6.</p>

<p>Compound 0831-0931 is a useful organic compound for research related to life sciences and the catalog number is T131638.</p>

<p>Eicosapentaenoyl-L-carnitine chloride is a long-chain acylcarnitine comprised of Eicosapentaenoic Acid and L-Carnitine. In a mouse model of myopia induced by defocus lenses, mice fed with diets rich in n-3/n-6 polyunsaturated fatty acids (PUFAs) showed increased levels of Eicosapentaenoyl-L-carnitine chloride in their eyes.</p>

1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].

N-(Azido-PEG4)-biocytin serves as a PEG-based PROTAC linker for PROTAC synthesis[1].

<p>KRL74 is a cyclic peptide inhibitor that interferes with the interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein (p6/UEV), with an IC50 of 5.44 μM and a Kd of 11.9 μM. It also inhibits the budding of HIV from host cells, exhibiting an IC50 of 2 μM in virus-like particle (VLP) budding assays.</p>

Tetrahydropyranyldiethyleneglycol is a polyethylene glycol (PEG)-based PROTAC linker utilized in the synthesis of PROTACs[1].

<p>4-Methylpentan-2-amine hydrochloride is classified as an aliphatic amine and acts as a stimulant. It has been identified in dietary supplements.</p>

Benzyloxy carbonyl-PEG3-C2-Boc, an alkyl/ether-based PROTAC linker, is a synthetic compound employed for the synthesis of PROTACs[1].

Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid is a polyethylene glycol (PEG) derived linker that is employed in PROTAC synthesis[1].

<p>(5α)-3,6-Dioxocholan-24-oic acid is a type of secondary bile acid.</p>

VEGFR-2-IN-57 (compound 6n) exhibits significant cytotoxicity on HUVEC cells, with an IC50 value of 28.77 nM.

<p>Ganosinensic acid C is a natural product that can be used as a reference standard. The CAS number of Ganosinensic acid C is 2231756-23-1.</p>

Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite: a PEG linker for PROTAC synthesis.