Otros inhibidores
Esta categoría abarca una amplia variedad de inhibidores que no encajan en las clasificaciones estándar, pero que son fundamentales para diversas investigaciones bioquímicas y farmacológicas. Estos inhibidores pueden dirigirse a vías, enzimas e interacciones moleculares únicas o menos estudiadas, proporcionando herramientas valiosas para áreas de investigación especializadas. En CymitQuimica, ofrecemos una selección diversa de inhibidores de alta calidad que abarcan múltiples objetivos biológicos y disciplinas de investigación, lo que le permite explorar nuevas vías terapéuticas y profundizar su comprensión de los procesos biológicos complejos.
Se han encontrado 37926 productos de "Otros inhibidores"
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MEIS-IN-1
CAS:<p>MEIS-IN-1 is a potent MEIS inhibitor that induces the expansion of hematopoietic stem cells in mice and humans.</p>Fórmula:C24H21F3N2O4Forma y color:SolidPeso molecular:458.43VEGFR-2-IN-10
<p>VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0.7 μM and no cytotoxic effects.</p>Fórmula:C20H21N3O2Forma y color:SolidPeso molecular:335.4Clavicoronic acid
CAS:<p>Clavicoronic acid, a β-lactamase inhibitor, boosts penicillin antibiotics against resistant bacteria.</p>Fórmula:C15H18O4Forma y color:SolidPeso molecular:262.3H 218-54
CAS:<p>H 218-54 is a renin inhibitor.</p>Fórmula:C37H56N2O5SForma y color:SolidPeso molecular:640.92YM-202074
CAS:<p>YM-202074: Selective mGlu1 antagonist, binds allosteric site (Ki=4.8 nM), inhibits mGlu1 (IC50=8.6 nM).</p>Fórmula:C22H30N4O2SForma y color:SolidPeso molecular:414.56MEIS-IN-2
<p>MEIS-IN-2 is an inhibitor of MEIS1. MEIS-IN-2 can be used in studies of cardiac regeneration and haematopoietic stem cell (HSC) regulation.</p>Fórmula:C23H21ClN2O4Forma y color:SolidPeso molecular:424.88ADH-353
CAS:<p>ADH-353 inhibits Aβ fibrillization and mitigates Aβ-induced cytotoxicity in SH-SY5Y and N2a cells, making it useful for studies related to Alzheimer's disease.</p>Fórmula:C27H38N8O6Forma y color:SolidPeso molecular:570.64Eprociclovir Na
CAS:<p>Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.</p>Fórmula:C11H14N5NaO3Forma y color:SolidPeso molecular:287.25H-Glu(4MβNA)-OH
CAS:<p>H-Glu(4MβNA)-OH serves as a substrate for aminopeptidases (APs).</p>Fórmula:C16H18N2O4Forma y color:SolidPeso molecular:302.33LGB-321 HCl
CAS:<p>LGB-321: potent, selective PIM kinase inhibitor, active against PIM2, halts diverse blood cancers' growth, orally effective in mice.</p>Fórmula:C23H23ClF3N5O2Forma y color:SolidPeso molecular:493.91MB725
CAS:<p>MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.</p>Fórmula:C18H21IN4O2SForma y color:SolidPeso molecular:484.35PKG1α activator 3
<p>PKG1α activator 3 is a PKG1α activator (EC50basal/partial=13/0.52 μM).</p>Fórmula:C27H26Cl2N2O6Forma y color:SolidPeso molecular:545.41Hesperidin dihydrochalcone
CAS:Hesperidin dihydrochalcone, a non-toxic sweetener with high sweetness and low calories, exhibits multiple biological activities including anti-oxidation, liver and kidney protection, bacteriostasis, and enhancement of gastrointestinal health.Fórmula:C28H36O15Forma y color:SolidPeso molecular:612.58Xylarianaphthol-1
CAS:<p>Xylarianaphthol-1 is an activator of p21 promoter in a p53-independent manner.</p>Fórmula:C16H20BrFN2O2Forma y color:SolidPeso molecular:371.24Diarylalkane derivative 1
CAS:<p>Diarylalkane derivative 1 is used for the research of pancreatitis.</p>Fórmula:C34H51NO4Pureza:98%Forma y color:SolidPeso molecular:537.77ZK168281
CAS:<p>ZK168281 is a 1α,25(OH)2D3 analog, VDR antagonist with 0.1 nM Kd, and blocks receptor CoA interaction.</p>Fórmula:C32H46O5Pureza:98%Forma y color:SolidPeso molecular:510.70ZIKV-IN-5
<p>ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.</p>Fórmula:C36H45NO4SiForma y color:SolidPeso molecular:583.83Edeine A1
CAS:<p>Edeine A1 inhibits DNA replication and protein biosynthesis, exhibiting activity against Gram-positive and Gram-negative bacteria, fungi, and yeasts.</p>Fórmula:C33H58N10O10Forma y color:SolidPeso molecular:754.875AEP-IN-1
<p>APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.</p>Fórmula:C18H27N3O3Forma y color:SolidPeso molecular:333.43Neuraminidase-IN-7
<p>Neuraminidase-IN-7, a thiophene, inhibits neuraminidase (IC50 0.03 μM), showing promise for flu research.</p>Fórmula:C21H20N2O6SForma y color:SolidPeso molecular:428.46AS-1940477 hydrobromide
CAS:<p>AS-1940477 hydrobromide is a p38 mitogen-activated protein kinase (MAPK) inhibitor.</p>Fórmula:C24H23BrFN5O2Forma y color:SolidPeso molecular:512.38Gypsetin
CAS:<p>Gypsetin inhibits the activity of acyl-CoA:cholesterol acyltransferase (ACAT), showing inhibitory effects on rat liver microsomal ACAT with an IC50 of 18 μM, and competes with oleoyl-CoA substrate, possessing a Ki value of 5.5 μM. Additionally, Gypsetin prevents the formation of cholesterol esters from oleic acid with an IC50 of 0.65 μM.</p>Fórmula:C32H36N4O4Forma y color:SolidPeso molecular:540.653PDE4-IN-5
<p>PDE4-IN-5: potent PDE4 inhibitor, IC50 = 3.1 nM, superb skin penetration, anti-psoriasis effect.</p>Fórmula:C21H28N2O3Forma y color:SolidPeso molecular:356.46TP-030-2
CAS:<p>TP-030-2 is a RIPK1 inhibitor (human K i =0.43 nM ; mouse IC 50 =100 nM) .</p>Fórmula:C23H21BrN4O3Forma y color:SolidPeso molecular:481.34RDN2150
CAS:<p>RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69</p>Fórmula:C28H29ClN8O4Forma y color:SolidPeso molecular:577.03C-di-IMP
CAS:<p>Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.</p>Fórmula:C20H22N8O14P2Forma y color:SolidPeso molecular:660.38Terfluranol
CAS:<p>Terfluranol, a benzyl derivative, is utilized as an antitumor medication.</p>Fórmula:C17H17F3O2Forma y color:SolidPeso molecular:310.31Copper(II) ionophore I
CAS:Copper(II) ionophore I is an active compound.Fórmula:C26H44N2S4Forma y color:SolidPeso molecular:512.90Anticancer agent 78
<p>Anticancer agent 78: anti-aromatase (IC50=0.9 μM), cytotoxic, potential in breast cancer research.</p>Fórmula:C19H14BrNO4Forma y color:SolidPeso molecular:400.22Transthyretin-IN-1
<p>Transthyretin-IN-1 inhibits TTR fibril formation, aiding Alzheimer’s research.</p>Fórmula:C10H9Br2NO4Forma y color:SolidPeso molecular:366.99mPGES1-IN-4
CAS:<p>mPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine compound acting as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and significantly suppresses acute inflammation models in vivo.</p>Fórmula:C27H25F2N3OForma y color:SolidPeso molecular:445.50Hynapene A
CAS:<p>Hynapene A exhibits an inhibitory minimum inhibitory concentration (MIC) of 123 μM against Eimeria tenella.</p>Fórmula:C18H28O5Forma y color:SolidPeso molecular:324.412Calphostin A
CAS:<p>Calphostins, from Cladosporium fungus, inhibit PKC; calphostin C is most potent, used as a biochemical tool.</p>Fórmula:C44H38O12Forma y color:SolidPeso molecular:758.77Anti-inflammatory agent 13
<p>Pentacyclic triterpene, Anti-inflammatory 13 inhibits DAMP/PAMP inflammation models.</p>Fórmula:C30H48O4Forma y color:SolidPeso molecular:472.7Salvinorin A Propionate
CAS:<p>Salvinorin A propionate: partial KOR agonist, Ki=32.6 nM, EC50=4.7 nM; ignores μ/δ/ORL-1, non-opioid receptors; less potent analgesic vs. salvinorin A.</p>Fórmula:C24H30O8Forma y color:SolidPeso molecular:446.49MPro N3
CAS:<p>Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.</p>Fórmula:C35H48N6O8Forma y color:SolidPeso molecular:680.79Glucopiericidin B
CAS:<p>Glucopiericidin B exhibits antibacterial activity.</p>Fórmula:C31H47NO9Forma y color:SolidPeso molecular:577.706Deoxyfuconojirimycin hydrochloride
CAS:<p>Deoxyfuconojirimycin hydrochloride acts as a specific competitive inhibitor targeting human liver α-L-fucosidase.</p>Fórmula:C6H14ClNO3Forma y color:SolidPeso molecular:183.63TCMDC-136230
<p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>Fórmula:C24H34N4O2SForma y color:SolidPeso molecular:442.62Enactin Ⅴa
CAS:<p>EnactinVa is a compound produced by the bacterium Streptomyces roseoviridis and exhibits relatively weak antifungal activity.</p>Fórmula:C19H38N2O5Forma y color:SolidPeso molecular:374.51512(S)-HEPE
CAS:<p>12(S)-HEPE, made from EPA by 12-LO, is an anti-inflammatory ω-3 derivative affecting leukotriene formation.</p>Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.45Naphthablin
CAS:<p>Naphthablin is a naphthoquinone compound that inhibits the function of the Abl oncogene. It prevents the morphological transformation of v-ablts-NIH3T3 cells induced by Abl and also suppresses RNA synthesis.</p>Fórmula:C29H36O8Forma y color:SolidPeso molecular:512.591Cilobamine (free base)
CAS:<p>Cilobamine: a stimulant antidepressant, inhibits norepinephrine-dopamine reuptake, based on dichloroisoprenaline structure.</p>Fórmula:C17H23Cl2NOForma y color:SolidPeso molecular:328.28GNTI TFA
CAS:<p>GNTI TFA is a selective kappa opioid receptor antagonist.</p>Fórmula:C31H31F6N5O7Forma y color:SolidPeso molecular:699.605-Hydroxy-3,4,7-triphenyl-2,6-benzofurandione
CAS:<p>5-Hydroxy-3,4,7-triphenyl-2,6-benzofurandione is an inhibitor of xanthine oxidase (XO) found in the fungus Peniophora sanguinea.</p>Fórmula:C26H16O4Forma y color:SolidPeso molecular:392.40DN-F01
<p>DN-F01 exhibits a potent calcium-dependent inhibitory effect on cardiac myofibrillar ATPase activity, with an IC50 of 11 ± 4 nmol/L.</p>Fórmula:C22H16N2O2Forma y color:SolidPeso molecular:340.37PDE4-IN-14
CAS:<p>PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, including</p>Fórmula:C19H20F2N4O3SForma y color:SolidPeso molecular:422.45Oudemansin A
CAS:<p>Oudemansin A is an antibiotic that targets fungi, inhibiting the synthesis of proteins, RNA, and DNA.</p>Fórmula:C17H22O4Forma y color:SolidPeso molecular:290.35P-gp inhibitor 2
CAS:<p>Potent P-gp inhibitor 2 reverses Doxorubicin resistance in colorectal carcinoma cells with IC50 of 0.22 µM.</p>Fórmula:C29H26N2O6Forma y color:SolidPeso molecular:498.53Antibacterial agent 69
<p>Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).</p>Fórmula:C24H19N3O4SForma y color:SolidPeso molecular:445.4917β-HSD1-IN-1
<p>17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research.</p>Fórmula:C21H21NO3Forma y color:SolidPeso molecular:335.4PI3K-IN-26
CAS:<p>PI3K-IN-26 is an effective PI3K inhibitor. PI3K-IN-26 inhibits the proliferation of SU-DHL-6 cells, IC50= 36 nM.</p>Fórmula:C21H18N6OSForma y color:SolidPeso molecular:402.47GLS1 Inhibitor-5
<p>GLS1 Inhibitor-5 (24y): Selective, oral glutaminase 1 inhibitor; IC50 68 nM; induces apoptosis; anti-tumor.</p>Forma y color:SolidMopivabil
<p>Mopivabil is the angiotensin II receptor antagonist[1].</p>Fórmula:C14H20O3Forma y color:SolidPeso molecular:236.31NTPDase-IN-1
<p>NTPDase-IN-1 selectively inhibits NTPDases 1, 2, 8 with IC50 of 0.05, 0.23, 0.54 μM. Non-competitive, K m 21 μM, used in cancer, immune, infection research.</p>Fórmula:C18H25N3OS2Forma y color:SolidPeso molecular:363.54Cilazapril HCl
CAS:<p>Cilazapril, also known as Ro 31 2848, is a potent ACE inhibitor used for hypertension.</p>Fórmula:C22H32ClN3O5Forma y color:SolidPeso molecular:453.96Isoleucyl tRNA synthetase-IN-2
CAS:<p>Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).</p>Fórmula:C22H33N5O8SForma y color:SolidPeso molecular:527.59MK-7445
CAS:<p>MK-7445 is a conformationally constrained inhibitor of non-nucleoside reverse transcriptase.</p>Fórmula:C21H13Cl2N7OForma y color:SolidPeso molecular:450.28EBOV-GP-IN-1
<p>EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).</p>Fórmula:C25H40ClN3O2Forma y color:SolidPeso molecular:450.06Clavamycin A
CAS:<p>Clavamycin A displays notable antifungal activity against Candida species, with its effects being antagonized by dipeptides or tripeptides, although not by amino acids. It lacks antibacterial properties and does not inhibit β-lactamase.</p>Fórmula:C16H22N4O9Forma y color:SolidPeso molecular:414.367Kirrothricin
CAS:<p>Kirrothricin exhibits antibacterial properties, but it is inactive against Bacillus subtilis, Escherichia coli, and fungi.</p>Fórmula:C44H64N2O10Forma y color:SolidPeso molecular:780.986Brostallicin HCl
CAS:<p>Brostallicin, a synthetic MGB, inhibits DNA replication in cancer cells, inducing cell death, effective against MMR-defective tumors.</p>Fórmula:C30H36BrClN12O5Forma y color:SolidPeso molecular:760.04MRS2279 diammonium
CAS:<p>MRS2279 diammonium, a P2Y1 antagonist with K i 2.5 nM, IC 50 51.6 nM, blocks ADP-induced platelet aggregation, pK b 8.05.</p>Fórmula:C13H24ClN7O8P2Forma y color:SolidPeso molecular:503.77LRH-1 modulator-1
CAS:<p>LRH-1 modulator-1: potent agonist, boosts IL-10, reduces IL-1b/TNFa, anti-inflammatory in gut.</p>Fórmula:C28H36N2O2SForma y color:SolidPeso molecular:464.669-O-Demethyltrigonostemone
CAS:<p>9-O-Demethyltrigonostemone is a natural IDO1 inhibitor, cytotoxic and antiplasmodial agent from the Roots of Strophioblachia fimbricalyx.</p>Fórmula:C19H20O4Forma y color:SolidPeso molecular:312.36WS-898
<p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>Fórmula:C33H25N7OSForma y color:SolidPeso molecular:567.66Heme Oxygenase-1-IN-2
<p>Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.</p>Fórmula:C19H18ClN3OForma y color:SolidPeso molecular:339.82CYP2C1/CYP2C19-IN-2
<p>CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.</p>Fórmula:C27H28N2O6SForma y color:SolidPeso molecular:508.59Revamilast sodium
CAS:<p>Revamilast sodium, also known as GRC4039 sodium, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritis</p>Fórmula:C18H8Cl2F2N3NaO4Forma y color:SolidPeso molecular:462.17Anti-ToCV agent 1
<p>Anti-ToCV agent 1 can be used as a potential anti-ToCV drug.</p>Fórmula:C22H19FN2O5SForma y color:SolidPeso molecular:442.46AL 6598
CAS:<p>AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.</p>Fórmula:C23H39ClO5Forma y color:SolidPeso molecular:431.01Neoenactin A
CAS:<p>Neoenactin A exhibits potent activity against yeasts and filamentous fungi.</p>Fórmula:C19H36N2O5Forma y color:SolidPeso molecular:372.5NI-Pano
<p>NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor capable of O2-dependent release of the compound panobinostat.</p>Fórmula:C26H28N6O4Forma y color:SolidPeso molecular:488.54Resorcinomycin A
CAS:<p>Resorcinomycin A is an antibiotic with potent antimycobacterial activity and relatively weaker activity against mycoplasma.</p>Fórmula:C14H20N4O5Forma y color:SolidPeso molecular:324.332Ribocil-C R enantiomer
<p>Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.</p>Fórmula:C21H21N7OSPureza:98%Forma y color:SolidPeso molecular:419.5ITK inhibitor 6
CAS:<p>ITK inhibitor 6 selectively targets ITK, BTK, JAK3, EGFR, LCK, blocks PLCγ1 and ERK1/2 phosphorylation, and inhibits cell proliferation.</p>Fórmula:C28H24F2N4O2Forma y color:SolidPeso molecular:486.51SIK1 activator 1
CAS:<p>SIK1 activator 1 boosts SIK1 phosphorylation, reduces type 2 diabetes hyperglycemia, and inhibits liver gluconeogenesis.</p>Fórmula:C23H32O6Forma y color:SolidPeso molecular:404.50Antileishmanial agent-6
<p>Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.</p>Fórmula:C24H26O8Forma y color:SolidPeso molecular:442.46ZK824859 hydrochloride
<p>ZK824859 hydrochloride: oral uPA inhibitor with IC50 of 79 nM (uPA), 1580 nM (tPA), 1330 nM (fibrin).</p>Fórmula:C23H23ClF2N2O4Forma y color:SolidPeso molecular:464.89DMP 728
CAS:<p>DMP 728 is an antagonist of Glycoprotein IIb-IIIa.</p>Fórmula:C26H40N8O10SPureza:98%Forma y color:SolidPeso molecular:656.71Irinotecan Carboxylate Sodium Salt
CAS:<p>Irinotecan Carboxylate Sodium Salt is a DNA topoisomerase inhibitor.</p>Fórmula:C33H39N4NaO7Forma y color:SolidPeso molecular:626.68J-104132
CAS:<p>J-104132: potent human ETA/B antagonist; Ki: ETA=0.034nM, ETB=0.104nM; prevents ET-1 effects, ED50 i.v.=0.045mg/kg, p.o.=0.35mg/kg.</p>Fórmula:C31H33NO7Pureza:98%Forma y color:SolidPeso molecular:531.60Elaiomycin
CAS:<p>Elaiomycin exhibits activity against Gram-positive bacteria, certain anaerobic bacteria, Eimeria tenella, and Eimeria stiedai.</p>Fórmula:C13H26N2O3Forma y color:SolidPeso molecular:258.357rel-MDM2/4-p53-IN-2
<p>Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.</p>Fórmula:C25H17Cl3FN3O3Forma y color:SolidPeso molecular:532.78IACS-8779 disodium
CAS:<p>IACS-8779 disodium: potent STING agonist, strong systemic anti-tumor effects, effective in melanoma model.</p>Fórmula:C21H23N9Na2O10P2S2Forma y color:SolidPeso molecular:733.52Moflomycin
CAS:<p>Moflomycin is an anthracycline derivative. It exhibits a higher antileukemic activity compared to other anthracyclines.</p>Fórmula:C25H25IO10Pureza:98%Forma y color:SolidPeso molecular:612.36G12Si-1
<p>G12Si-1 selectively binds and inhibits K-Ras(G12S) to block oncogenic signaling and nucleotide exchange.</p>Fórmula:C29H32ClN5O3Forma y color:SolidPeso molecular:534.05Ceclazepide
CAS:<p>Ceclazepide is an antagonist of cholecystokinin receptor.</p>Fórmula:C30H32N6O5Pureza:98%Forma y color:SolidPeso molecular:556.61DDCPPB-Glu
CAS:<p>DDCPPB-Glu is a 6-5 fused ring heterocycle antifolate that shows antitumor activity.</p>Fórmula:C22H27N5O5Pureza:98%Forma y color:SolidPeso molecular:441.48MSA-2 dimer
CAS:<p>MSA-2 dimer: selective oral non-nucleotide STING agonist, Kd=145 μM, long-term antitumor effect, non-covalent, higher permeability.</p>Fórmula:C29H28O8S2Forma y color:SolidPeso molecular:568.66SLC7A11-IN-2
CAS:<p>SLC7A11-IN-2 (Compound 1) is an inhibitor of SLC7A11/xCT. It disrupts the oxidative balance in HeLa cells by decreasing intracellular glutathione levels and increasing oxidative stress, thereby inducing cell death with an IC50 of 10.23 μM. Molecular dynamics simulations have demonstrated that SLC7A11-IN-2 exhibits a stronger binding affinity to SLC7A11 compared to Erastin. This compound is useful for research in the field of cervical cancer.</p>Fórmula:C19H24N4O3Forma y color:SolidPeso molecular:356.42GSK 932121
CAS:<p>GSK 932121: potent antimalarial, targets P. falciparum by inhibiting cytochrome bc1 in the electron transport chain.</p>Fórmula:C20H15ClF3NO4Pureza:98%Forma y color:SolidPeso molecular:425.79A 74273
CAS:<p>A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.</p>Fórmula:C44H74N4O8Pureza:98%Forma y color:SolidPeso molecular:787.08SX 3202
CAS:<p>SX 3202 is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy.</p>Fórmula:C17H11BrFN3O4Forma y color:SolidPeso molecular:420.19DMGF
CAS:<p>DMGF, a biflavonoid from Taxus, induces apoptosis, autophagy, and inhibits B16F10 cell motility and MMP-2 expression, hindering melanoma metastasis.</p>Fórmula:C32H22O10Forma y color:SolidPeso molecular:566.51MK-7128
CAS:<p>MK-7128 is a CB1 receptor inverse agonist.</p>Fórmula:C29H25ClF2N4O2Forma y color:SolidPeso molecular:534.98Galactostatin
CAS:<p>Galactostatin is an inhibitor of β-galactosidase.</p>Fórmula:C6H13NO5Forma y color:SolidPeso molecular:179.171Ezomycin B2
CAS:<p>Ezomycin B2 is an antibiotic with antifungal activity.</p>Fórmula:C19H25N5O13Forma y color:SolidPeso molecular:531.427DNDI-8219
CAS:<p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>Fórmula:C13H10F3N3O5Forma y color:SolidPeso molecular:345.23(-)-Adenophorine
CAS:<p>(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.</p>Fórmula:C8H17NO4Forma y color:SolidPeso molecular:191.22SENP2-IN-1
CAS:<p>SENP2-IN-1 selectively inhibits SENP2, SENP1, and SENP5 with low IC50 values; useful in cancer studies.</p>Fórmula:C32H29N3O5S2Forma y color:SolidPeso molecular:599.72FK-906 HCl
CAS:<p>FK-906 HCl is a human renin inhibitor used for the long-term treatment of patients with essential hypertension.</p>Fórmula:C40H64ClN7O7Forma y color:SolidPeso molecular:790.44Antitumor agent-75
<p>Antitumor agent-75 is a novel and potent antitumor agent.</p>Fórmula:C26H23FN6Forma y color:SolidPeso molecular:438.5Kaitocephalin
CAS:<p>Kaitocephalin: naturally occurring, non-selective antagonist blocking glutamate receptors, made by Eupenicillium shearii fungus.</p>Fórmula:C18H21Cl2N3O9Forma y color:SolidPeso molecular:494.28Motuporin
CAS:<p>Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).</p>Fórmula:C40H57N5O10Forma y color:SolidPeso molecular:767.91Afeletecan HCl
CAS:<p>Afeletecan (BAY 56-3722) is a water-soluble, anti-cancer camptothecin conjugated to a carbohydrate, inhibiting DNA replication and inducing apoptosis.</p>Fórmula:C45H50ClN7O11SForma y color:SolidPeso molecular:932.44DC4SMe
CAS:<p>DC4SMe, a prodrug for targeted tumor therapy and ADC synthesis, has IC50s: 1.9 nM (Ramos), 2.9 nM (Namalwa), 1.8 nM (HL60/s).</p>Fórmula:C35H31ClN5O7PS2Pureza:98%Forma y color:SolidPeso molecular:764.21ICA-105665
CAS:<p>ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.</p>Fórmula:C19H15F2N3O2Pureza:98%Forma y color:SolidPeso molecular:355.34Glidobactin F
CAS:<p>Glidobactin F is an antitumor antibiotic effective against pathogenic fungi and yeasts. It has been shown to increase the survival time of mice inoculated with leukemia P388 cells.</p>Fórmula:C25H40N4O6Forma y color:SolidPeso molecular:492.608Fandosentan
CAS:<p>Fandosentan is an endothelin receptor antagonist.</p>Fórmula:C25H18F3NO6SForma y color:SolidPeso molecular:517.47G-4120
CAS:<p>G-4120 is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis.</p>Fórmula:C26H36N8O11SForma y color:SolidPeso molecular:668.68Antitumor agent-51
<p>Antitumor agent-51 targets osteosarcoma with 21.9 nM IC50, high selectivity, and low toxicity.</p>Fórmula:C23H25N5O2SForma y color:SolidPeso molecular:435.54U 80215
CAS:<p>U 80215 is an enzyme-competitive inhibitor.</p>Fórmula:C42H60N8O6SForma y color:SolidPeso molecular:805.04Cremimycin
CAS:<p>Cremimycin exhibits activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) of 0.2-0.39 μg/mL. Additionally, Cremimycin demonstrates cytotoxic effects on mouse tumor cell lines P388, L1210, IMC, S180, B16, and SS3 in vitro.</p>Fórmula:C35H53NO9Forma y color:SolidPeso molecular:631.797UCN-02
CAS:<p>UCN-02 (7-epi-Hydroxystaurosporine) is a PKC inhibitor produced by Streptomyces N-126 strain, which inhibits PKA.</p>Fórmula:C28H26N4O4Pureza:98%Forma y color:SolidPeso molecular:482.53Fonsartan free acid
CAS:<p>Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.</p>Fórmula:C26H32N4O5S2Pureza:98%Forma y color:SolidPeso molecular:544.69RN941
CAS:<p>RN941 is a highly potent Bruton's tyrosine kinase (BTK) inhibitor.</p>Fórmula:C34H34FN7O5Pureza:98%Forma y color:SolidPeso molecular:639.68P7170
CAS:<p>P7170 is an anti-cancer agent active as an mTORC1/C2 and activin receptor-like kinase 1 (ALK1) inhibitor.</p>Fórmula:C21H16F3N9Forma y color:SolidPeso molecular:451.42Anti-inflammatory agent 23
<p>Anti-inflammatory agent 23 blocks LPS-induced NO (IC50: 0.449 μM) and binds p65 well.</p>Fórmula:C34H49NO6Forma y color:SolidPeso molecular:567.76O4
CAS:<p>O4 is a novel stabilizer of amyloid- fibrils. O4 used for accelerating the formation of end-stage mature fibrils.</p>Fórmula:C24H15NO7Pureza:98%Forma y color:SolidPeso molecular:429.38Retelliptine
CAS:<p>Retelliptine, a DNA topoisomerase II inhibitor, is used potentially for the treatment of cancer.</p>Fórmula:C25H32N4OPureza:98%Forma y color:SolidPeso molecular:404.55ALK5-IN-7
CAS:<p>ALK5-IN-7 inhibits ALK5, useful in TGF-β disease research like cancer, fibrosis, and autoimmune disorders. See WO2021129621A1.</p>Fórmula:C26H28N4O3SForma y color:SolidPeso molecular:476.59Dup-714
CAS:<p>Dup-714 is a thrombin inhibitor.</p>Fórmula:C21H33BN6O5Pureza:98%Forma y color:SolidPeso molecular:460.33ZK118182 isopropyl ester
CAS:<p>ZK118182 isopropyl ester is a PG analog with potent DP-agonist activity (EC50 = 16.5 nM) and high affinity for the DP receptor (Ki = 74 nM).</p>Fórmula:C23H37ClO5Pureza:98%Forma y color:SolidPeso molecular:428.99Arterolane maleate
CAS:<p>Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.</p>Fórmula:C26H40N2O8Pureza:98%Forma y color:SolidPeso molecular:508.612Lasonolide A
CAS:<p>Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.</p>Fórmula:C41H60O9Forma y color:SolidPeso molecular:696.91Enprostil
CAS:<p>Enprostil: synthetic PGE2 analog, reduces gastric acid, protects mucosa, lowers post-meal gastrin, treats ulcers effectively and safely.</p>Fórmula:C23H28O6Pureza:98%Forma y color:SolidPeso molecular:400.46BXL0124
CAS:<p>BXL0124 is a gemini vitamin D analog which targets CD44-STAT3 signaling and inhibits breast cancer invasion.</p>Fórmula:C32H44F6O4Forma y color:SolidPeso molecular:606.68KC-11404
CAS:<p>KC-11404 is an LTB4 inhibitor for the treatment of b-cell leukemias and lymphomas, potently inhibiting histamine, platelet activating factor and 5-lipoxygenase.</p>Fórmula:C28H38N4OForma y color:SolidPeso molecular:446.632,3-Dimethoxy-4-(methylthio)benzeneethanamine
CAS:<p>2,3-Dimethoxy-4-(methylthio)benzeneethanamine (compound 22) is an analog of methoxybenzothiazine, employed in researching pharmacological agents that model human psychiatric disorders.</p>Fórmula:C11H17NO2SForma y color:SolidPeso molecular:227.32Porphine
CAS:<p>Porphine (Porphyrin), the parent compound of the porphyrin family, plays a crucial role within biological systems.</p>Fórmula:C20H14N4Forma y color:SolidPeso molecular:310.355-Fluoroorotic acid monohydrate
CAS:<p>5-Fluoroorotic acid (monohydrate) (5-Fluorouracil-6-carboxylic acid Mono(hydrate); 5-FOA) is employed to detect the expression of the URA3 gene in yeast molecular genetic constructs. Yeast possessing an active URA3 gene (which encodes orotidine-5'-monophosphate decarboxylase) convert 5-FOA into 5-fluorodeoxyuridine, a substance toxic to cells. Yeast strains with mutations in the URA3 gene that confer resistance can grow in the presence of 5-FOA if uracil is added to the medium.</p>Fórmula:C5H5FN2O5Forma y color:SolidPeso molecular:192.10CRV431
CAS:<p>CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM).</p>Fórmula:C67H122N12O13Forma y color:SolidPeso molecular:1303.76MTSES sodium
CAS:<p>MTSES sodium (Sodium (2-Sulfonatoethyl)methanethiosulfonate) is a negatively charged, membrane-impermeable methanethiosulfonate (MTS). This MTS compound can react with thiol groups to form mixed disulfides, frequently utilized in studying cysteine residues on proteins.</p>Fórmula:C3H7NaO5S3Forma y color:SolidPeso molecular:242.276-Aminopyridine-3-thioamide
CAS:<p>6-Aminopyridine-3-thioamide is a compound noted for its anticancer properties, capable of inhibiting the activity of specific enzymes that affect cell proliferation and survival. Furthermore, it has been studied for its potential to mitigate neurodegenerative diseases, exhibiting capabilities to enhance neural functions. The structural characteristics of 6-Aminopyridine-3-thioamide render it a significant bioactive molecule in compound development.</p>Fórmula:C6H7N3SForma y color:SolidPeso molecular:153.21Antitumor agent-187
CAS:<p>Antitumor agent-187 (compound I) is an isoflavone derivative with antitumor activity. It exhibits IC50 values of 5.23 μM and 2.63 μM against A2780 and SKOV3 cell lines, respectively.</p>Fórmula:C24H26N2O7Forma y color:SolidPeso molecular:454.47CEP-2563
CAS:<p>CEP-2563 is a prodrug of CEP-751. It also used as an antitumor agent, inhibiting protein kinases.</p>Fórmula:C36H41ClN6O6Pureza:98%Forma y color:SolidPeso molecular:689.20Antitumor agent-48
<p>Antitumor agent-48, a 2,3-dehydrosilybin derivative, exhibits cytotoxicity on MCF-7, NCI-H1299, HepG2, HT29 cells; IC50 ranging 8.06-16.51 µM.</p>Fórmula:C35H34N2O14Forma y color:SolidPeso molecular:706.65AY-22,252
CAS:<p>AY-22,252 is an inhibitor of beef heart & rat brain nucleoside-3',5'- monophosphate phosphodiesterase.</p>Fórmula:C27H37NaO7Forma y color:SolidPeso molecular:496.57OP-2507
CAS:<p>OP-2507, a prostacyclin agonist, is used potentially for the treatment of hepatic insufficiency and hypertension.</p>Fórmula:C25H41NO4Pureza:98%Forma y color:SolidPeso molecular:419.6CH-38083
CAS:<p>CH-38083 is a selective and effective alpha-2 adrenoceptors antagonist.</p>Fórmula:C18H24ClNO3Pureza:98%Forma y color:SolidPeso molecular:337.84PD-149163
CAS:<p>PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.</p>Fórmula:C42H71N9O6Forma y color:SolidPeso molecular:798.07Everafenib
<p>Everafenib: potent BRAF inhibitor, crosses blood-brain barrier, hinders MAPK, effective on V600EBRAF cells, outperforms other drugs in trials.</p>Fórmula:C20H23ClFN5O2S2Forma y color:SolidPeso molecular:484.01Resolvin E4
CAS:<p>RvE4, a bioactive lipid from eicosapentaenoic acid and synthesized by 15-LO, is anti-inflammatory and boosts efferocytosis in human macrophages.</p>Fórmula:C20H30O4Forma y color:SolidPeso molecular:334.45MMG-11 quarterhydrate
<p>MMG-11 quarterhydrate, a potent hTLR2 antagonist, inhibits TLR2/1 and TLR2/6 with IC50s of 1.7μM and 5.7μM; low toxicity.</p>Fórmula:C15H16O8Forma y color:SolidPeso molecular:310.78Revamilast
CAS:<p>Revamilast, also known as GRC4039, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritis</p>Fórmula:C18H9Cl2F2N3O4Forma y color:SolidPeso molecular:440.18Antileishmanial agent-4
<p>Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].</p>Fórmula:C17H18N4O4Forma y color:SolidPeso molecular:342.35Novokinin
CAS:<p>Angiotensin AT2 receptor agonist</p>Fórmula:C39H61N11O7Pureza:98%Forma y color:SolidPeso molecular:795.97Tilpisertib fosmecarbil
CAS:<p>Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.</p>Fórmula:C35H36ClN8O7PForma y color:SolidPeso molecular:747.14PD-1/PD-L1-IN-13
<p>PD-1/PD-L1-IN-13 is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM for PD-1/PD- L1 interaction.PD-1/PD-L1-IN-13 promotes CD8+ T-</p>Fórmula:C36H34ClF2N3O9Forma y color:SolidPeso molecular:726.12CYP1B1-IN-2
<p>CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of CYP1B1, a cytochrome P450 enzyme. It exhibits an IC50 value of 0.52 nM [1].</p>Fórmula:C20H11F3O2Forma y color:SolidPeso molecular:340.3LI-3948
CAS:<p>IP6K-IN-2 (compound 29c) is an IP6K inhibitor that demonstrates oral bioavailability and the ability to permeate the blood-brain barrier (IC 50 : 15.8 nM), making it suitable for research on central nervous system diseases.</p>Fórmula:C19H16Cl2FN3O3Forma y color:SolidPeso molecular:424.25Heme Oxygenase-1-IN-3
CAS:<p>Heme Oxygenase-1-IN-3 (compound 4) serves as a potent and selective inhibitor of heme oxygenase-1 (HO-1) with a dissociation constant (Kd) of 141 nM, making it suitable for use in cancer and neurodegenerative disease research.</p>Fórmula:C22H18BrFN4O2SForma y color:SolidPeso molecular:501.37HR-546
CAS:<p>HR-546 is a prostaglandin E2 and prostaglandin F2alpha antagonist.</p>Fórmula:C26H44O6Forma y color:SolidPeso molecular:452.62PfPKG-IN-1
<p>PfPKG-IN-1, an imidazole-based inhibitor, targets the Plasmodium falciparum cyclic guanosine monophosphate-dependent protein kinase (PfPKG).</p>Fórmula:C24H22ClN7OSForma y color:SolidPeso molecular:492Bcl-2-IN-8
<p>Bcl-2-IN-8: potent, hinders cell growth/migration, induces apoptosis, promising in triple-negative breast cancer research.</p>Fórmula:C36H44O6Forma y color:SolidPeso molecular:572.73Chitinase-IN-4
<p>Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.</p>Fórmula:C21H24ClN7Forma y color:SolidPeso molecular:409.92ETH 157
CAS:<p>ETH 157 is a synthetic neutral carrier-based Na+ selective microelectrode, with sufficient selectivity against K+, Ca2+, and Mg2+ for extracellular measurement of Na+ activity.</p>Fórmula:C36H32N2O4Forma y color:SolidPeso molecular:556.65Barixibat
CAS:<p>Barixibat is a bile acid transport inhibitor.</p>Fórmula:C42H55N5O8Forma y color:SolidPeso molecular:757.91T-3861174
CAS:<p>T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation.</p>Fórmula:C26H25FN6O2Forma y color:SolidPeso molecular:472.51DGY-08-097
CAS:<p>DGY-08-097: potent HCV NS3 degrader, low resistance risk, strong inhibition in cells, DC50 of 50nM at 4h.</p>Fórmula:C60H76N10O14Forma y color:SolidPeso molecular:1161.3Lafadofensine (D-(-)-Mandelic acid)
<p>Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.</p>Fórmula:C32H32F2N2O6Forma y color:SolidPeso molecular:578.6Fipronil desulfinyl
CAS:<p>Fipronil desulfinyl, a photodegradation product of the insecticide Fipronil, exhibits similar in vivo toxicity to Fipronil and possesses higher environmental toxicity.</p>Fórmula:C12H4Cl2F6N4Forma y color:SolidPeso molecular:389.08GK241
CAS:<p>GK241 (compound 31a-c), a 2-oxoamide-based compound, exhibits inhibitory activity against group IIA secretory phospholipase A2 (GIIA sPLA2) in humans and mice, with IC50 values of 143 nM and 68 nM, respectively. The mechanism of inhibition has been explored through molecular dynamics simulations.</p>Fórmula:C21H39NO4Forma y color:SolidPeso molecular:369.54OXS007417
<p>OXS007417 induces AML cell differentiation at 48 nM EC50 and shows potent in vivo antitumor effects.</p>Fórmula:C20H14F3N3OForma y color:SolidPeso molecular:369.34Metocurine chloride
CAS:<p>Metocurine: a muscle relaxant, not for kidney failure patients as it's kidney-excreted.</p>Fórmula:C40H48Cl2N2O6Forma y color:SolidPeso molecular:723.72PPARγ agonist 1
<p>PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects.</p>Fórmula:C34H39NO3Forma y color:SolidPeso molecular:509.68BDZ-h
CAS:<p>BDZ-h inhibits both closed/open states of all 4 homomeric & 2 GluA2R-complex AMPA receptors.</p>Fórmula:C21H21N5O3SForma y color:SolidPeso molecular:423.49CYP2C9/CYP2C19-IN-1
<p>CYP2C9/CYP2C19-IN-1 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.</p>Fórmula:C27H28N2O6SForma y color:SolidPeso molecular:508.59GS-9160
CAS:<p>GS-9160 is a novel and potent inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase (IN) that specifically targets the process of strand transfer.</p>Fórmula:C20H18FN3O4SForma y color:SolidPeso molecular:415.44rel-MDM2/4-p53-IN-3
<p>rel-MDM2/4-p53-IN-3 inhibits MDM2/4-p53 PPI, IC50: MDM2 18.5nM, MDM4 14.8nM, targets cancer research.</p>Fórmula:C25H24Cl2FN3O3Forma y color:SolidPeso molecular:504.38YM-60828 dihydrochloride
CAS:<p>YM-60828 dihydrochloride is a Factor Xa (FXa) inhibitor and anticoagulant used in the treatment of venous thromboembolic disease.</p>Fórmula:C27H33Cl2N5O5SForma y color:SolidPeso molecular:610.55MurB-IN-1
<p>MurB-IN-1 (compound 44) inhibits key bacterial enzyme MurB with 3.57 μM affinity, offering treatment potential against P. aeruginosa.</p>Fórmula:C12H7Cl2F3N2O2Forma y color:SolidPeso molecular:339.1Anti-inflammatory agent 19
<p>Anti-inflammatory agent 19: NO inhibitor (IC50: 36μM), blocks HMGB1, for late-stage inflammation, relevant for COVID-19, sepsis.</p>Fórmula:C30H50O7Forma y color:SolidPeso molecular:522.71FR 900452
CAS:<p>FR 900452 is a platelet activating factor antagonist from fermentatiion products of Streptomyces phaeofaciens.</p>Fórmula:C22H25N3O3SForma y color:SolidPeso molecular:411.52EICAR
CAS:<p>EICAR: IMP dehydrogenase inhibitor with anticancer and antiviral properties, failed in leukemia trials, active against various viruses but not SARS.</p>Fórmula:C11H13N3O5Forma y color:SolidPeso molecular:267.24NNTA
CAS:<p>NNTA is a highly selective and potent activator of μ/κ-opioid heteromers.</p>Fórmula:C31H32N2O4Forma y color:SolidPeso molecular:496.60Ascofuranone
CAS:<p>Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH</p>Fórmula:C23H29ClO5Forma y color:SolidPeso molecular:420.93OncoFAP
CAS:<p>OncoFAP is an ultra-high affinity fibroblast activating protein (FAP) ligand with potential tumour targeting.</p>Fórmula:C21H19F2N5O5Pureza:99.77%Forma y color:SolidPeso molecular:459.40A1-Phytoprostane-I
CAS:<p>A1-Phytoprostane-I: cyclopentenone from α-linolenic acid in plants, induces gene expression & increases phytoalexin synthesis.</p>Fórmula:C18H28O4Forma y color:SolidPeso molecular:308.41Latrunculin M
CAS:<p>Latrunculin M, a novel marine toxin, disrupts microfilament organization in cultured cells.</p>Fórmula:C21H33NO5SForma y color:SolidPeso molecular:411.55FCE-24379
CAS:<p>FCE-24379 is a selective antagonist of vascular serotonin receptors that has been shown to lowers blood pressure in hypertensive rats.</p>Fórmula:C20H22N4O2Forma y color:SolidPeso molecular:350.41VRT-18858
CAS:<p>VRT-18858 is a metabolite of VX-740.</p>Fórmula:C24H25N5O7Forma y color:SolidPeso molecular:495.489(S)-HEPE
CAS:<p>9(S)-HEPE is a monohydroxy fatty acid derived from EPA. The biological activity of 9(S)-HEPE has not been documented.</p>Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.45KP 10614
CAS:<p>KP 10614 is a new prostacyclin analog that inhibits platelet-polymorphonuclear leukocyte interaction.</p>Fórmula:C23H32O4Forma y color:SolidPeso molecular:372.50MPO-IN-8
CAS:<p>MPO-IN-8, an orally active myeloperoxidase (MPO) inhibitor, effectively inhibits the production of hypochlorous acid in neutrophils and the release of extracellular traps (NETosis). In mice exhibiting gouty arthritis, it reduces swelling, decreases peroxidase activity, and lowers IL-1β levels.</p>Fórmula:C12H9N3O2Forma y color:SolidPeso molecular:227.22Dimesna free acid
CAS:<p>Dimesna (BNP-778), when used in conjunction with active cancer chemotherapy agents, can reduce the toxicity associated with uremia.</p>Fórmula:C4H10O6S4Forma y color:SolidPeso molecular:282.38Netobimin
CAS:<p>Netobimin is an anthelmintic effective against naturally acquired gastrointestinal nematodes in cows.</p>Fórmula:C14H20N4O7S2Forma y color:SolidPeso molecular:420.46FWM-1
<p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>Fórmula:C15H11ClN4O4S2Forma y color:SolidPeso molecular:410.86BAY-693
CAS:<p>BAY-693 is a ERK5 negative control agent with IC50 (ERK5) = 6400 nM. Its analog, BAY-885, is a potent and selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM</p>Fórmula:C26H30F3N7O2Forma y color:SolidPeso molecular:529.56M-COPA
CAS:<p>M-COPA disrupts Golgi, blocks MET & Arf1 activation, and inhibits angiogenesis via VEGFR & NF-kB pathways.</p>Fórmula:C25H34N2O2Forma y color:SolidPeso molecular:394.55LASSBio-1632
<p>LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR & lung TNF-α, crosses BBB.</p>Fórmula:C18H20N2O6SForma y color:SolidPeso molecular:392.43Tofogliflozin
CAS:<p>Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).</p>Fórmula:C22H26O6Pureza:98%Forma y color:SolidPeso molecular:386.44ORP-101
CAS:<p>ORP-101: large, stable molecule with partial μ agonist, full κ antagonist properties.</p>Fórmula:C60H84N2O8Forma y color:SolidPeso molecular:961.32AGN-204396
CAS:<p>AGN-204396 is an antagonist that selectively blocks the activity of prostamides (prostaglandin-ethanolamides).</p>Fórmula:C32H44FN3O4Forma y color:SolidPeso molecular:553.71ATX inhibitor 12
<p>Oral ATX inhibitor 12 (IC50: 1.72 nM) at 60 mg/kg prevents lung damage in C57Bl/6J mice.</p>Fórmula:C30H34FN5O2Forma y color:SolidPeso molecular:515.62PARP1-IN-5
<p>PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.</p>Fórmula:C25H24N2O5SForma y color:SolidPeso molecular:464.53Leukotriene F-4 sulfone
CAS:<p>Leukotriene F-4 sulfone induces vascular permeability changes.</p>Fórmula:C28H44N2O10SForma y color:SolidPeso molecular:600.72Mevidalen HBA
CAS:<p>Mevidalen (LY3154207), a potent D1 positive allosteric modulator, is in clinical trials for Lewy body dementia.</p>Fórmula:C31H35Cl2NO6Forma y color:SolidPeso molecular:588.52Steroid sulfatase/17β-HSD1-IN-4
<p>Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a potent dual inhibitor of steroid sulfatase ( STS ) and 17β-hydroxysteroid dehydrogenase type 1 ( 17β HSD1 ).</p>Fórmula:C18H17N3O4S2Forma y color:SolidPeso molecular:403.48
