Otros inhibidores

<p>m-Anisidine, 4-(benzyloxy)- is a bioactive chemical.</p>

<p>P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123</p>

<p>BMS-419437 is a bio-active chemical.</p>

<p>Trichophydine is a useful organic compound for research related to life sciences and the catalog number is T124429.</p>

<p>ALS22335 is an antiviral agent.</p>

<p>Water-soluble 3-Azidopropionic Acid Sulfo-NHS Ester reacts via Click Chemistry; labels proteins' amines.</p>

<p>Praeroside III is a useful organic compound for research related to life sciences. The catalog number is T126292 and the CAS number is 117306-98-6.</p>

<p>L 659286 is one kind of cephalosporin derivative.</p>

<p>8(S)-HETrE: a fatty acid by rabbit enzyme from dihomo-γ-linolenic acid, similar to 8(S)-HETE.</p>

<p>Geissoschizine is a natural product that can be used as a reference standard. The CAS number of Geissoschizine is 439-66-7.</p>

<p>Gambogin is a useful organic compound for research related to life sciences and the catalog number is T125580.</p>

<p>Primordazine NC-6364997 is a negative control for Primordazine A and Primordazine B.</p>

<p>VUF 5207 is a bioactive chemical.</p>

<p>Axillarin 4'-glucuronide is a useful organic compound for research related to life sciences. The catalog number is T124474 and the CAS number is 65039-74-9.</p>

<p>Levetimide C-11 is a radiotracer.</p>

<p>Lyxonic acid is an aldonic acid.</p>

<p>Maejaposide C is a useful organic compound for research related to life sciences. The catalog number is T125307 and the CAS number is 221467-31-8.</p>

<p>Benzenesulfonic acid, 3-hydrazinyl- is a bioactive chemical.</p>

<p>Homothiocystine has appreciable activity as a substrate.</p>

<p>Lup-12-en-3-ol, (3beta,18beta,19beta)- is a bioactive chemical.</p>

<p>5'-hydroxy Meloxicam is one of the metabolites of meloxicam (MEL).</p>

<p>Isocalolongic acid is a useful organic compound for research related to life sciences. The catalog number is T124889 and the CAS number is 40737-92-6.</p>

<p>Rubenorside B is a natural product that can be used as a reference standard. The CAS number of Rubenorside B is 218615-42-0.</p>

<p>Petasinine is a useful organic compound for research related to life sciences and the catalog number is T124363.</p>

<p>Anticancer agent 111 (compound 11), exhibiting anticancer activity, serves as a potent inhibitor of cytochrome P450, particularly targeting CYP3A4 with an</p>

<p>WW-781 is used to measure action potential propagation in the heart.</p>

<p>Canophyllol is a useful organic compound for research related to life sciences and the catalog number is T131495.</p>

<p>Tetraketide is a natural product that can be used as a reference standard.</p>

<p>Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate), a sulfur-containing isomer of 2'-deoxyguanosine-5'-O-triphosphate (dGTP), functions as an inhibitor of the</p>

<p>Compound N094-0017 is a useful organic compound for research related to life sciences and the catalog number is T131159.</p>

<p>Adamantane diazirine is a biochemical.</p>

<p>Nortenuazonic acid is a useful organic compound for research related to life sciences and the catalog number is T125622.</p>

<p>Feruloyl arabinobiose is a bioactive chemical extracted from the cell walls of spinach cells.</p>

<p>Transdermal Peptide is a 11-amino acid peptide, binds to Na+/K+-ATPase beta-subunit (ATP1B1), and enhances the transdermal delivery of many macromolecules.</p>

<p>Compound N039-0038 is a useful organic compound for research related to life sciences and the catalog number is T131267.</p>

<p>Hygrophylline is a useful organic compound for research related to life sciences and the catalog number is T124965.</p>

<p>Lucartamide is a bioactive chemical.</p>

<p>Uridine 5’-methylenediphosphate (UMP-CP), a hydrolytically stable derivative of UDP and agonist of the purinergic P2Y14 receptor, exhibits selective inhibition</p>

<p>Clorexolone is a low-ceiling sulfonamide diuretic.</p>

<p>Brachynoside is a useful organic compound for research related to life sciences and the catalog number is T125839.</p>

<p>Choline oxidase is an enzyme that facilitates the conversion of choline to glycine betaine through an intermediate, betaine aldehyde, during the synthesis of</p>

<p>Perfluidone is a a fluorinated arylalkylsulphonamide plant growth regulator and herbicide.</p>

<p>Cyanazine is a triazine herbicide controlling grass and broadleaf weeds, non-genotoxic, selective, and widely used in agriculture and environmental research.</p>

<p>Limonene oxide, (-)- is a bioactive chemical.</p>

<p>Org 2058 is a synthetic progestin.</p>

<p>Stachybotrysin B from S. chartarum, antiviral (HIV IC50=19.2μM) &amp; anticancer (K562 IC50=21.72μM, HeLa IC50=39.63μM, HL-60 IC50=18.5μM).</p>

<p>TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells-2 (TREM2) agonist (EC50: 3.0 μM-100 μM).</p>

<p>MK-251 is a potential bioactive agent. No further details yet.</p>

<p>Spectabiline is a useful organic compound for research related to life sciences and the catalog number is T124728.</p>

<p>DiIC1(5): a fluorescent probe for mitochondrial potential disruption, detects cell death stages and PTMs, with 659/666 nm excitation/emission.</p>

<p>Acronycine (Acronine) is a useful organic compound for research related to life sciences and the catalog number is T131464.</p>

<p>Tunicamycin VII is a useful organic compound for research related to life sciences. The catalog number is T124449 and the CAS number is 66081-36-5.</p>

<p>Compound N039-0023 is a useful organic compound for research related to life sciences and the catalog number is T131274.</p>

<p>R-724 is a bioactive chemical.</p>

<p>Euchrenone A10 is a useful organic compound for research related to life sciences and the catalog number is T125597.</p>

<p>Lentztrehalose B, a microbial disaccharide metabolite isolated from Lentzea, exhibits a range of biological activities. At a concentration of 100 µM, it demonstrates antioxidant properties in an oxygen radical absorbance capacity (ORAC) assay. Furthermore, Lentztrehalose B at 10 mM inhibits porcine kidney trehalase, an enzyme involved in trehalose metabolism. Additionally, it induces autophagy in MeWo melanoma and OVK18 ovarian cancer cells when applied at 100 mM.</p>

<p>(-)-De-O-methylcentrolobin is a useful organic compound for research related to life sciences. The catalog number is T125088 and the CAS number is 30359-00-3.</p>

<p>Lucifer yellow is a coloring agent used in indicators and reagents.</p>

<p>Dihydroaspyrone is a useful organic compound for research related to life sciences and the catalog number is T130822.</p>

<p>A1-226 is a cephalosporin of the class of β-lactam antibiotics, it is originally derived from the fungus Acremonium.</p>

<p>3-Hydroxy-2-phenyl-propanamide is a useful organic compound for research related to life sciences.</p>

<p>Mal-Ph-CONH-PEG4-NHS ester, a non-cleavable four-unit polyethylene glycol (PEG) ADC linker, plays a crucial role in the synthesis of antibody-drug conjugates (</p>

<p>24,25-Dihydrolanosterol (Lanostenol) is a chemical compound found in the seeds of the red pepper (Capsicum annuum).</p>

<p>Pulsatilloside C, an isolated compound from Pulsatilla koreana, exhibits notable inhibition of adipocyte differentiation.</p>

<p>Matesaponin 1 is a useful organic compound for research related to life sciences. The catalog number is T126122 and the CAS number is 126622-38-6.</p>

<p>Akhdarenol is a biochemical.</p>

<p>(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is derived exclusively from the roots of Sophora flavescens.</p>

<p>Benzyl-PEG4-Azido is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>Eriosematin A is a useful organic compound for research related to life sciences and the catalog number is T125571.</p>

<p>PF-1163A, a depsipeptide antifungal compound isolated from Penicillium, blocks ergosterol synthesis with an IC50 of 12 ng/ml. This compound specifically inhibits the enzyme ERG25p, a C-4 methyl oxidase in the ergosterol biosynthetic pathway, leading to its antifungal activity. Notably, in Saccharomyces cerevisiae modified to express ERG biosynthesis genes, PF-1163A exhibits an inhibition concentration (MIC value) of 12.5 µg/ml against ERG25p, though strains overexpressing ERG25p show resistance. Additionally, PF-1163A effectively suppresses the growth of Candida albicans (MIC = 8 µg/ml), without affecting other Candida species, Aspergillus fumigatus, or HepG2 cells. Remarkably, it enhances the efficacy of fluconazole against azole-resistant C. albicans strains, showing a significant decrease in MICs (1 and 0.0078 µg/ml alone and in combination, respectively). PF-1163A distinguishes itself from PF-1163B by its more polar nature.</p>

<p>AB 74 is an antibiotic.</p>

<p>m-Anisidine, 4-(heptyloxy)- is a bioactive chemical.</p>

<p>Lentztrehalose A, a disaccharide microbial metabolite identified in Lentzea, exhibits a range of biological activities. This compound specifically inhibits M. smegmatis trehalase—an enzyme involved in trehalose metabolism—more effectively than trehalase from porcine kidney, with IC50 values of 0.67 mM and &gt;20 mM, respectively. Additionally, Lentztrehalose A at a concentration of 100 mM promotes autophagy in MeWo melanoma and OVK18 ovarian cancer cells. When administered at 50 mg/kg daily, it enhances survival rates and impedes tumor growth in a Sarcoma 180 murine sarcoma model.</p>

<p>7-Geranyloxy-1,3-dihydroxyxanthone is a useful organic compound for research related to life sciences and the catalog number is T129912.</p>

<p>Chlortoluron-mecoprop mixt. is a bioactive chemical mixture.</p>

<p>L-Pyrohomoglutamic acid, an amino acid, aids in synthesizing FKBP ligands and HDAC inhibitors.</p>

<p>2E-Decenoylpiperidide is a useful organic compound for research related to life sciences and the catalog number is T125821.</p>

<p>Kayexalate, a cation-exchange resin, functions as an oral inhibitor of plasma potassium levels and is utilized in the investigation of hyperkalemia [1] [2].</p>

<p>Schizokinen is a citrate-containing dihydroxamate and a siderophore produced by Bacillus megaterium and Anabaena sp.</p>

<p>Mal-CO-PEG5-NHS ester is a 5-unit PEG-based, non-cleavable ADC linker utilized in the fabrication of antibody-drug conjugates (ADCs).</p>

<p>(+)-Goniothalesdiol, from G. borneensis bark, has anti-leukemic and pesticidal properties, with ED50 ≥30 μg/ml against P388.</p>

<p>Jaceoside is a useful organic compound for research related to life sciences. The catalog number is T125193 and the CAS number is 25474-11-7.</p>

<p>Formamide, N-(5-(p-aminophenoxy)pentyl)- is a bioactive chemical.</p>

<p>Eicosapentaenoic acid is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases.</p>

<p>Ceylantin is a natural product that can be used as a reference standard. The CAS number of Ceylantin is 68421-13-6.</p>

<p>Negative control for st-Ht31 .</p>

<p>β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate.</p>

<p>NCGC00538431 is a potent SIRPα-CD47 modulator [1].</p>

<p>2’-O-Methylguanosine-5’-O-triphosphate (2’-methyl GTP) acts as an inhibitor targeting the hepatitis C virus (HCV) non-structural protein 5B (NS5B; with an IC50</p>

<p>Promoxolane is a biochemical.</p>

<p>Isobauerenol is a triterpenoid compound isolated from sterile stems.</p>

<p>DSPE-MPEG(2000), a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE), is employed in the formulation of liposomes for delivering anticancer and antimalarial agents.</p>

<p>6-O-demethyl Griseofulvin is a metabolite of the antifungal griseofulvin .1,2</p>

<p>"PDS-IN-1 potently inhibits Oryza sativa phytoene desaturase (OsPDS), exhibiting herbicidal activity [1]."</p>

<p>Dimethicone 350: silicone oil, fully methylated siloxanes, used in skin/hair care.</p>

<p>Denticulatain B is a useful organic compound for research related to life sciences and the catalog number is T125518.</p>

<p>Tuberculosis Inhibitor 10 moderately inhibits the enzyme MSMEG_6649 and potentiates the antimycobacterial activity of PAS [1].</p>

<p>Lentztrehalose C, a disaccharide identified in Lentzea, exhibits autophagy-inducing activity.</p>

<p>Phomopsidin is a useful organic compound for research related to life sciences. The catalog number is T125428 and the CAS number is 199173-60-9.</p>

<p>Sodium D-mannuronate, derived from the seaweed Macrocystis pyrifera, shows promise as a therapeutic agent in studies of autoimmune encephalomyelitis (EAE),</p>

<p>Parkeyl acetate is a bioactive chemical.</p>

<p>(–)-β-Sesquiphellandrene, a sesquiterpene identified in Z. officinale, exhibits antiviral and anticancer properties. It effectively inhibits rhinovirus IB virus replication in a plaque reduction assay with an IC50 of 0.44 µM. Additionally, at a concentration of 10 µM, it demonstrates cytotoxicity to HCT116 cells.</p>

<p>Z-Pro-Ala, an acid carboxypeptidase, can be isolated from the grains and leaves of Triticum aestivum L. (wheat) [1].</p>

<p>PF-03622905: potent ATP-competitive PKC inhibitor, IC50: 5.6-74.1 nM for PKCα/βI/βII/γ/θ, high specificity for PKC.</p>

<p>β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI.</p>

<p>Kingiside is a natural product that can be used as a reference standard. The CAS number of Kingiside is 25406-67-1.</p>

<p>Keto-itraconazole is a metabolite of Itraconazole.</p>

<p>Phenol, m-(2-(dipropylamino)ethyl)-, hydrobromide is a bioactive chemical.</p>

<p>EP 171 is a potent agonist of TP-receptors.</p>