Otros inhibidores

<p>HO-PEG-amine (MW 1000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>Ajugamarin L2 is a natural product that can be used as a reference standard.</p>

<p>KDdiA-PC is an oxidized phosphatidylcholine (oxPC) directly related to atherosclerosis.</p>

<p>Antioxidant agent-17 (compound 59) potently inhibits superoxide anion generation, exhibiting an IC50 value of 9.06 nM [1].</p>

<p>4”-O-Glucosylvitexin is a naturally derived compound that inhibits TPO activity. It is extracted and purified from the fruit of hawthorn (Crataegus pinnatifida).</p>

<p>(-)-Carveol is an unsaturated, cyclic monoterpenoid alcohol; used in cosmetics for fragrance and as a food flavor additive.</p>

<p>Bromo-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>TKD (450-463), a 14-peptide (TKDNNLLGRFELSG), exhibits the ability to stimulate NK cells' cytolytic and proliferative activities at concentrations comparable to the full-length Hsp70 protein.</p>

<p>Kefton-2 is bioactive chemical.</p>

<p>Kibdelone A, a natural heterocyclic polyketide, was first isolated from the soil actinomycete Kibdelosporangium. It exhibits potent and selective cytotoxicity against various human tumor cell lines, in addition to showing significant antibacterial and nematocidal activity.</p>

<p>7-Hydroxyflavanone-glucoside is a useful organic compound for research related to life sciences and the catalog number is T130446.</p>

<p>Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.<br>[1]. Wei S et al. Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice. Immunopharmacol Immunotoxicol. 2016 Jun;38(3):197-204.</p>

<p>N-Mal-N-bis(PEG4-amine) is a PEG-based linker utilized for PROTAC synthesis[1].</p>

<p>WKYMVm is a selective FPR2 agonist with high affinity, which was identified through screening of a synthetic peptide library.</p>

<p>Gestonorone is steroid progesterone in the 19-nometroprogesterone and 17α -hydroxyprogesterone groups.</p>

<p>The HiBiT tag, a complementary peptide (VSGWRLFKKIS), exhibits high affinity for LgBiT. It is fused with the Gβ subunit of the receptor. The interaction between LgBiT and HiBiT facilitates the stabilization of ETR and G proteins. Additionally, HiBiT can be attached to target proteins (GFP) to quantify their transport to the cytosol.</p>

<p>Gepefrine, (+/-)- is a bioactive chemical.</p>

<p>Lunularin is a bioactive chemical.</p>

<p>Phenethyl rutinoside is a useful organic compound for research related to life sciences and the catalog number is T130918.</p>

<p>m-PEG7-CH2-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>Nephilatoxin 9 is a Joro spider toxin (JSTX) from Nephila clavata.</p>

<p>7-Hydroxy-beta-carboline-1-propionic acid is a useful organic compound for research related to life sciences and the catalog number is T125336.</p>

<p>Ormutivimab (rhRIG), a recombinant human monoclonal antibody designed to target the rabies virus, effectively neutralizes various strains and demonstrates</p>

<p>M&amp;amp;B 4261 is a bioactive chemical.</p>

<p>Detajmium bitartrate is used as an antiarrhythmic drug.</p>

<p>Jmv 332 is a cyclic analog of the C-terminal hexapeptide of CCK. It is a CCK/gastrin receptor agonist.</p>

<p>Oleyl myristate is a bioactive chemical.</p>

<p>Tresperimus TFA can be used as an immune agent and can be used to study retinitis.</p>

<p>Ustusolate C and ustusolate E exhibit moderate cytotoxicity against A549 and HL-60 cells with IC50 values of 10.5 and 9.0 microM, respectively.</p>

<p>SRA880: sst1-receptor antagonist, low affinity for other somatostatin receptors, binds to dopamine D4, may enhance antidepressant effects.</p>

<p>RGD-PEG-Cy3 is a fluorescent labeling reagent that combines the Cy3 fluorescent dye, peptide (RGD), and polyethylene glycol (PEG). The Cy3 fluorophore is commonly employed in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry, with a peak emission wavelength of approximately 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that targets tumor tissues specifically by binding to αvβ3 and αvβ5 integrin receptors, which are involved in tumor neovascularization.</p>

<p>1-Phenyloctane enhances the liquid-phase exfoliation of graphene in organic solvents.</p>

<p>Enkephalin, pen(2,5)- is a bioactive chemical.</p>

<p>XY-52 (Compound 32), an ST2 (Stimulation-2) inhibitor, exhibits IC50 values of 5.68 μM and 4.59 μM in the AlphaLISA and HEK-Blue assays, respectively.</p>

<p>H2N-PEG8-Hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>2,4-Dimethylbenzaldehyde is an aromatic aldehyde widely used in biochemical experiments and drug synthesis research.</p>

<p>TP-5801 TFA is an orally active inhibitor of TNK1, a non-receptor tyrosine kinase, with an IC50 value of 1.40 nM, demonstrating anti-tumor activity [1].</p>

<p>CP-18 F-18 is a DEVD (the caspase 3 substrate recognition motif) that is an imaging tracer for caspase-3 activity in apoptotic cells.</p>

<p>Ethyl brevifolincarboxylate is a natural product for research related to life sciences. The catalog number is TN5744 and the CAS number is 107646-82-2.</p>

<p>Robustaside G is a natural product that can be used as a reference standard. The CAS number of Robustaside G is 1262023-42-6.</p>

<p>IT-143A from Streptomyces sp. IT-143.1 kills M. luteus (MIC 6.25 μg/ml), and some fungi (MIC 12.5-25 μg/ml).</p>

<p>5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound primarily located in the leaves of Ilex glabra L. Gray (Aquifoliaceae).</p>

<p>Glucobrassicin is a glucosinolate (GSL) that can be isolated from wild carrot (Raphanus raphanistrum L.). It is utilized in research on biofumigation or allelopathic plants for weed management.</p>

<p>ATG-031 is a humanized anti-CD24 monoclonal antibody that shows antitumor activity in vitro and in vivo.ATG-031 blocks the CD24-Siglec10 axis in TME.</p>

<p>(±)-7-epiJasmonic acid, the primary metabolite in the 12-oxo phytodienoic acid pathway of 13(S)-hydroperoxy linolenic acid metabolism in plants, is synthesized initially as the more active (+)-7-epijasmonic acid. It quickly epimerizes to the more stable (−)-7-jasmonic acid isomer, demonstrating its biological relevance. Acting as a plant growth regulator, (±)-7-epiJasmonic acid triggers various signal transduction pathways, which can either promote growth or inhibit it, likely as a response to stress conditions.</p>

<p>Danaidal is a useful organic compound for research related to life sciences and the catalog number is T125138.</p>

<p>Metrazifone is a potential bioactive agent. No detail information yet.</p>

<p>Amino-PEG24-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>Carbamic acid, N-mercapto-N-methyl-, m-isopropylphenyl ester is a bioactive chemical.</p>

<p>Methyl ganoderate F significantly inhibited the induction of Epstein-Barr virus early antigen (EBV-EA).</p>