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Señalización citoesquelética

Señalización citoesquelética

Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.

Se han encontrado 1381 productos de "Señalización citoesquelética"

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  • DM1-SMe

    CAS:
    <p>DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.</p>
    Fórmula:C36H50ClN3O10S2
    Pureza:99.61%
    Forma y color:Solid
    Peso molecular:784.38
  • Defactinib hydrochloride

    CAS:
    <p>Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.</p>
    Fórmula:C20H22ClF3N8O3S
    Pureza:98.06% - 98.78%
    Forma y color:Solid
    Peso molecular:546.95
  • AKT-IN-6

    CAS:
    <p>AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.</p>
    Fórmula:C22H20FN5O
    Pureza:98.68%
    Forma y color:Solid
    Peso molecular:389.43
  • JB002

    CAS:
    <p>JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM.</p>
    Fórmula:C18H15NO3
    Pureza:99.74%
    Forma y color:Soild
    Peso molecular:293.32
  • Arimoclomol

    CAS:
    <p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>
    Fórmula:C14H20ClN3O3
    Pureza:99.15%
    Forma y color:Solid
    Peso molecular:313.78
  • JH-VIII-157-02

    CAS:
    <p>JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.</p>
    Fórmula:C28H27N5O2
    Pureza:99.58%
    Forma y color:Solid
    Peso molecular:465.55
  • Firategrast

    CAS:
    <p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>
    Fórmula:C27H27F2NO6
    Pureza:99.16%
    Forma y color:Solid
    Peso molecular:499.5
  • SB-216

    CAS:
    <p>SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.</p>
    Fórmula:C17H18N4O2
    Pureza:99.70%
    Forma y color:Solid
    Peso molecular:310.35
  • Terflavoxate

    CAS:
    <p>Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine.</p>
    Fórmula:C26H29NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:419.51
  • LY3372689

    CAS:
    <p>LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.</p>
    Fórmula:C16H22FN5O3S
    Pureza:99.43% - 99.53%
    Forma y color:Solid
    Peso molecular:383.44
  • UMK57

    CAS:
    <p>UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,</p>
    Fórmula:C17H17N3S
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:295.4
  • PPY A

    CAS:
    <p>PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cells</p>
    Fórmula:C22H20N4O2
    Pureza:98.77%
    Forma y color:Solid
    Peso molecular:372.42
  • Iroxanadine

    CAS:
    <p>Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation in</p>
    Fórmula:C14H20N4O
    Pureza:98.04% - 99.04%
    Forma y color:Solid
    Peso molecular:260.33
  • DZ2002

    CAS:
    <p>DZ2002: Oral, reversible SAHH inhibitor (Ki=17.9 nM), low-toxicity, immunosuppressive, counters dermal fibrosis, used in autoimmune research.</p>
    Fórmula:C10H13N5O3
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:251.24
  • CID-663143

    CAS:
    <p>CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.</p>
    Fórmula:C19H18N4O2S
    Pureza:99.68% - 99.77%
    Forma y color:Solid
    Peso molecular:366.44
  • JB061


    <p>JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle</p>
    Fórmula:C19H17NO4
    Pureza:99.67%
    Forma y color:Soild
    Peso molecular:323.34
  • Rosabulin

    CAS:
    <p>v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency.</p>
    Fórmula:C22H16N4O2S
    Pureza:98.06%
    Forma y color:Solid
    Peso molecular:400.45
  • Tubulin inhibitor 8

    CAS:
    <p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>
    Fórmula:C21H14N2O3
    Pureza:98.51% - 99.87%
    Forma y color:Solid
    Peso molecular:342.35
  • AZ13705339

    CAS:
    <p>AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM.</p>
    Fórmula:C33H36FN7O3S
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:629.75
  • EMT inhibitor-1

    CAS:
    <p>EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.</p>
    Fórmula:C12H12Cl2N2O2S
    Pureza:99.53%
    Forma y color:Solid
    Peso molecular:319.21
  • JG-231

    CAS:
    <p>JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.</p>
    Fórmula:C22H18BrCl2N3OS4
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:619.47
  • AMP-PCP disodium

    CAS:
    <p>AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM.</p>
    Fórmula:C11H16N5Na2O12P3
    Pureza:99.32%
    Forma y color:Solid
    Peso molecular:549.17
  • CMPF

    CAS:
    <p>CMPF is a microtubule protein inhibitor that can be used to study tumors.</p>
    Fórmula:C12H16O5
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:240.25
  • Conteltinib

    CAS:
    <p>Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.</p>
    Fórmula:C32H45N9O3S
    Pureza:98.12% - 99.54%
    Forma y color:Solid
    Peso molecular:635.82
  • Dynapyrazole A

    CAS:
    <p>Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).</p>
    Fórmula:C20H12ClIN4O
    Pureza:98.01%
    Forma y color:Solid
    Peso molecular:486.69
  • Elarofiban

    CAS:
    <p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>
    Fórmula:C22H32N4O4
    Pureza:98.76%
    Forma y color:Solid
    Peso molecular:416.51
  • para-Nitroblebbistatin

    CAS:
    <p>para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.</p>
    Fórmula:C18H15N3O4
    Pureza:99.09% - 99.84%
    Forma y color:Solid
    Peso molecular:337.33
  • Erbulozole

    CAS:
    <p>Erbulozole (R 55104) is a synthetic microtubule inhibitor with anti-invasive activity that induces Wernicke's encephalopathy-like neurotoxicity.</p>
    Fórmula:C24H27N3O5S
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:469.55
  • JB062

    CAS:
    <p>JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and &gt;100 μM against skeletal muscle myosin, cardiac</p>
    Fórmula:C19H17NO4
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:323.34
  • DCPLA-ME

    CAS:
    <p>DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative</p>
    Fórmula:C21H38O2
    Pureza:99.80%
    Forma y color:Solid
    Peso molecular:322.53
  • BMD4503-2

    CAS:
    <p>BMD4503-2 is a competitive inhibitor of the LRP5/6-sclerostin complex that restores the activity of the Wnt/β-catenin signaling pathway cancer.</p>
    Fórmula:C26H21N5O3S
    Pureza:99.18%
    Forma y color:Solid
    Peso molecular:483.54
  • TCS 2210

    CAS:
    <p>TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.</p>
    Fórmula:C18H17N3O3
    Pureza:98.62%
    Forma y color:Solid
    Peso molecular:323.35
  • BIRT-377

    CAS:
    <p>BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).</p>
    Fórmula:C18H15BrCl2N2O2
    Pureza:99.93%
    Forma y color:Solid
    Peso molecular:442.13
  • Bis-T-23

    CAS:
    <p>Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative.</p>
    Fórmula:C23H20N4O8
    Pureza:96.81% - 98.13%
    Forma y color:Solid
    Peso molecular:480.43
  • Elsibucol

    CAS:
    <p>Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant,</p>
    Fórmula:C35H54O4S2
    Pureza:99.73%
    Forma y color:Solid
    Peso molecular:602.93
  • SNX0723

    CAS:
    <p>SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.</p>
    Fórmula:C22H26FN3O3
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:399.46
  • Nilotinib hydrochloride

    CAS:
    <p>Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.</p>
    Fórmula:C28H23ClF3N7O
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:565.98
  • PVZB1194

    CAS:
    <p>PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through</p>
    Fórmula:C13H9F4NO2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:319.28
  • SB-267268

    CAS:
    <p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>
    Fórmula:C22H24F3N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:451.44
  • CNS-11

    CAS:
    <p>CNS-11, a compound that disaggregates tau fibrils, is utilized in Alzheimer's disease (AD) research [1].</p>
    Fórmula:C25H21N3O2
    Forma y color:Solid
    Peso molecular:395.45
  • MC-Val-Cit-PAB-Ispinesib

    CAS:
    <p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>
    Fórmula:C59H71ClN10O10
    Forma y color:Solid
    Peso molecular:1115.71
  • Oxaline

    CAS:
    <p>Oxaline, a fungal alkaloid derived from Penicillium oxalicum, impedes tubulin polymerization, leading to cell cycle arrest at the M phase [1] [2].</p>
    Fórmula:C24H25N5O4
    Forma y color:Solid
    Peso molecular:447.49
  • Tubulin polymerization-IN-52

    CAS:
    <p>Tubulin polymerization-IN-52 (compound SC23) effectively inhibits tubulin polymerization, exhibiting an IC50 value of 2.9 μM [1].</p>
    Fórmula:C21H18F3N5O3
    Forma y color:Solid
    Peso molecular:445.39
  • Demethylasterriquinone B1

    CAS:
    <p>insulin receptor (IR) activator</p>
    Fórmula:C32H30N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:506.59
  • WAY 316606 hydrochloride

    CAS:
    <p>WAY 316606 hydrochloride is a chemical compound that serves as an inhibitor of sFRP-1 (secreted protein), which functions as an endogenous antagonist of the Wnt (secreted glycoprotein). Its affinity for sFRP-1 is measured through the FP (fluorescence polarization) binding assay, revealing an IC50 (half maximal inhibitory concentration) of 0.5 μM [1].</p>
    Fórmula:C18H20ClF3N2O4S2
    Forma y color:Solid
    Peso molecular:484.94
  • Valecobulin hydrochloride

    CAS:
    <p>Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.</p>
    Fórmula:C26H29ClN6O5S
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:573.06
  • Paluratide

    CAS:
    <p>Paluratide (LUNA18) is a reversible KRAS inhibitor oral , which inhibits cancer cell proliferation by phosphorylating ERK and AKT, RAS with (GEFs).</p>
    Fórmula:C73H105F5N12O12
    Pureza:98.70%
    Forma y color:Solid
    Peso molecular:1437.68
  • BIO-7662

    CAS:
    <p>BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.</p>
    Fórmula:C38H48N6O8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:748.89
  • ER degrader 7

    CAS:
    <p>ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor.</p>
    Fórmula:C33H31F4N3O5SSe
    Forma y color:Solid
    Peso molecular:736.63
  • ASN90

    CAS:
    <p>ASN90 is a specific, orally active inhibitor of the O-GlcNAcase (OGA) enzyme, demonstrating an IC50 of 10.2 nM.</p>
    Fórmula:C17H21N5O3S
    Forma y color:Solid
    Peso molecular:375.45
  • Zaurategrast

    CAS:
    <p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>
    Fórmula:C26H25BrN4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:521.41
  • Akt-I-1,2

    CAS:
    <p>Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.</p>
    Fórmula:C23H22ClN3
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:375.89
  • HSP90-IN-29

    CAS:
    <p>HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].</p>
    Fórmula:C19H20ClN3O4
    Forma y color:Solid
    Peso molecular:389.83
  • BI-1950

    CAS:
    <p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>
    Fórmula:C32H26Cl2FN7O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:646.5
  • 3,4',5-Trismethoxybenzophenone

    CAS:
    <p>3,4',5-Trismethoxybenzophenone (compound 16a) is an effective inhibitor of tubulin assembly, demonstrating a half-maximal inhibitory concentration (IC 50) of 2.6 µM [1].</p>
    Fórmula:C16H16O4
    Forma y color:Solid
    Peso molecular:272.3
  • TCS 21311

    CAS:
    <p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ &amp; GSK3β; &gt;100x selective over JAK1, JAK2, TYK2.</p>
    Fórmula:C27H25F3N4O4
    Pureza:99.39% - ≥98%
    Forma y color:Solid
    Peso molecular:526.51
  • Tirofiban HCl

    CAS:
    <p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>
    Fórmula:C22H37ClN2O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:477.06
  • KSP-IA

    CAS:
    <p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>
    Fórmula:C21H22F2N2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:356.41
  • Integrin Antagonists 27

    CAS:
    <p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>
    Fórmula:C24H20N4O5
    Forma y color:Solid
    Peso molecular:444.44
  • Kif15-IN-2

    CAS:
    <p>Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.</p>
    Fórmula:C20H20N6O4S
    Pureza:98.17%
    Forma y color:Solid
    Peso molecular:440.48
  • PAK4-IN-1

    CAS:
    <p>PAK4-IN-1: selective, potent oral PAK4 inhibitor; stable in acid/neutral; shows strong anti-tumor in vivo.</p>
    Fórmula:C26H30ClN7O5
    Forma y color:Solid
    Peso molecular:556.01
  • Porcn-IN-2

    CAS:
    <p>Porcn-IN-2 (Example 107) is a potent Wnt pathway inhibitor, exhibiting an IC50 of 0.05 nM.</p>
    Fórmula:C24H17F3N6O
    Forma y color:Solid
    Peso molecular:462.43
  • CCT251455

    CAS:
    <p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>
    Fórmula:C26H26ClN7O2
    Pureza:99.1% - 99.1%
    Forma y color:Solid
    Peso molecular:503.98
  • 3-Hydroxyxanthone

    CAS:
    <p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>
    Fórmula:C13H8O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:212.2
  • αvβ6 integrin inhibitor 2

    CAS:
    <p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>
    Fórmula:C21H30N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:386.49
  • NTRC 0066-0

    CAS:
    <p>NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.</p>
    Fórmula:C33H39N7O2
    Pureza:98.30%
    Forma y color:Solid
    Peso molecular:565.71
  • HSP90-IN-27

    CAS:
    <p>HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].</p>
    Fórmula:C18H21N3O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:343.44
  • MK-6240

    CAS:
    <p>MK-6240: A tau PET tracer with high specificity for NFTs binding.</p>
    Fórmula:C16H11FN4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:278.28
  • Carotegrast

    CAS:
    <p>Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.</p>
    Fórmula:C27H24Cl2N4O5
    Forma y color:Solid
    Peso molecular:555.41
  • THK-5105

    CAS:
    <p>THK-5105, a tau-binding arylquinoline, could be an 18F-PET imaging probe for Alzheimer's disease.</p>
    Fórmula:C20H21FN2O2
    Forma y color:Solid
    Peso molecular:340.39
  • IWP 12

    CAS:
    <p>IWP 12 is a potent inhibitor of porcupine (Porcn), blocking Wnt signaling and inhibiting fin regeneration in adult and juvenile fish.</p>
    Fórmula:C18H18N4O2S3
    Pureza:98.88%
    Forma y color:Solid
    Peso molecular:418.56
  • KU-177

    CAS:
    <p>KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.</p>
    Fórmula:C27H23NO8
    Pureza:96.92% - 98.54%
    Forma y color:Solid
    Peso molecular:489.47
  • Gly-Arg-Gly-Asp-Ser TFA

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.</p>
    Fórmula:C19H31F3N8O11
    Forma y color:Solid
    Peso molecular:604.49
  • Lamifiban

    CAS:
    <p>Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.</p>
    Fórmula:C24H28N4O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:468.5
  • SC-52012

    CAS:
    <p>SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.</p>
    Fórmula:C25H30N4O6
    Pureza:97.20%
    Forma y color:Solid
    Peso molecular:482.53
  • Pin1 modulator 1

    CAS:
    <p>Pin1 modulator 1 (compound IIb-219) is a specific β-Catenin targeting agent that inhibits the Wnt pathway and is applicable in researching Wnt-mediated diseases, including cancer [1].</p>
    Fórmula:C18H15NO3S2
    Forma y color:Solid
    Peso molecular:357.44
  • β-Catenin modulator-3

    CAS:
    <p>β-Catenin modulator-3 (compound IIa-112), an oxazole and thiazole-based chemical entity, serves as a potent and selective modulator of β-Catenin [1].</p>
    Fórmula:C21H22N2O3S
    Forma y color:Solid
    Peso molecular:382.48
  • Pterostilbene-isothiocyanate

    CAS:
    <p>Pterostilbene-isothiocyanate (PTER-ITC) demonstrates strong anticancer properties in vitro, particularly disrupting the interaction between β-catenin and TCF-4</p>
    Fórmula:C18H19N3O3S
    Forma y color:Solid
    Peso molecular:357.43
  • PKC-θ inhibitor 1

    CAS:
    <p>PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)</p>
    Fórmula:C17H15F3N4O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:348.32
  • 22-(4′-py)-JA

    CAS:
    <p>22-(4′-py)-JA, a semisynthetic derivative of junamycin A isolated from the Thai blue sponge (Xestospongia sp.), exhibits antimetastatic properties by inhibiting</p>
    Fórmula:C32H30N4O8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:598.6
  • PBB3

    CAS:
    <p>PBB3 is a tau-specific PET tracer.</p>
    Fórmula:C17H15N3OS
    Forma y color:Solid
    Peso molecular:309.39
  • AT7867 hydrochloride

    CAS:
    <p>AT7867 hydrochloride is a potent inhibitor of AKT and p70 S6 kinase, displaying oral activity and demonstrating an anticancer effect [1].</p>
    Fórmula:C20H21Cl2N3
    Forma y color:Solid
    Peso molecular:374.31
  • TC-I 15

    CAS:
    <p>α2β1 integrin inhibitor</p>
    Fórmula:C23H28N4O6S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:520.62
  • L-739758

    CAS:
    <p>L-739758 is a glycoprotein IIb/IIIa inhibitor.</p>
    Fórmula:C22H26N4O5S3
    Forma y color:Solid
    Peso molecular:522.66
  • BCR-ABL-IN-4

    CAS:
    <p>BCR-ABL-IN-4: Anticancer BCR-ABL inhibitor; stops K562 cells (IC50: 0.67 nM), targets T315I Ba/F3 cells (IC50: 16 nM).</p>
    Fórmula:C27H24ClF2N5O4
    Forma y color:Solid
    Peso molecular:555.96
  • (-)-Indolactam V

    CAS:
    <p>(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.</p>
    Fórmula:C17H23N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:301.38
  • β-catenin-IN-4

    CAS:
    <p>β-Catenin-IN-4 is a β-catenin inhibitor characterized by a K_i value of 0.64 μM.</p>
    Fórmula:C38H33ClF3N5O9
    Forma y color:Solid
    Peso molecular:796.14
  • L 738167

    CAS:
    <p>L 738167 is a potent antagonist of the long-acting fibrinogen receptor.</p>
    Fórmula:C25H34N6O6S
    Forma y color:Solid
    Peso molecular:546.64
  • Solenopsin

    CAS:
    <p>Solenopsin is an ATP-competitive inhibitor of AKT(IC50 : 10 μM) .</p>
    Fórmula:C17H35N
    Pureza:98%
    Forma y color:Solid
    Peso molecular:253.47
  • SEN461

    CAS:
    <p>SEN461 is a wnt inhibitor.</p>
    Fórmula:C25H34N4O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:486.56
  • HDAC-IN-55

    CAS:
    <p>HDAC-IN-55(8j) is a small-molecule inhibitor that enhances E-cadherin expression and suppresses cancer cell proliferation [1].</p>
    Fórmula:C17H17N3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:311.34
  • Levocabastine hydrochloride

    CAS:
    <p>Levocabastine HCl is an agent with antihistaminic activity.</p>
    Fórmula:C26H30ClFN2O2
    Forma y color:Solid
    Peso molecular:456.98
  • Heclin

    CAS:
    <p>Heclin is an inhibitor of HECT E3 ubiquitin ligase that acts by inhibiting Smurf2, Nedd4, and WWP1 with IC50 values of 6.8, 6.3, and 6.9 μM, respectively.</p>
    Fórmula:C17H17NO3
    Pureza:95.79%
    Forma y color:Solid
    Peso molecular:283.32
  • αvβ1 integrin-IN-2

    CAS:
    <p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>
    Fórmula:C29H38N4O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:506.64
  • CT-721

    CAS:
    <p>CT-721: potent, time-bound Bcr-Abl inhibitor, IC50 21.3 nM, effective against CML.</p>
    Fórmula:C30H29ClN6O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:525.04
  • Litronesib

    CAS:
    <p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>
    Fórmula:C23H37N5O4S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:511.7
  • AKT-IN-13

    CAS:
    <p>AKT-IN-13 inhibits Akt1, Akt2, Akt3 (IC50: 1.6, 2.4, 0.3 nM); used in cancer research.</p>
    Fórmula:C24H31ClN6O2
    Forma y color:Solid
    Peso molecular:470.99
  • ATN-161

    CAS:
    <p>ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.</p>
    Fórmula:C23H35N9O8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:597.64
  • VTX-27

    CAS:
    <p>VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).</p>
    Fórmula:C20H24ClFN6O
    Pureza:99.84%
    Forma y color:Solid
    Peso molecular:418.9
  • Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2

    CAS:
    <p>Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 demonstrates serum stability and non-toxicity to neuronal cells, while selectively inhibiting the fibrilization of tau in</p>
    Fórmula:C38H65N11O9
    Forma y color:Solid
    Peso molecular:819.99