Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1460 productos de "Señalización citoesquelética"
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DHNQ
CAS:<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Fórmula:C18H14N2OForma y color:SolidPeso molecular:274.32NSC305787
CAS:NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.Fórmula:C25H30Cl2N2OPureza:99.40%Forma y color:SolidPeso molecular:445.42Clathrin-IN-25
CAS:Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.Fórmula:C19H13KNO5SForma y color:SolidPeso molecular:406.47BGB659
CAS:<p>BGB659 is effective inhibitor of RAF.</p>Fórmula:C29H29F3N4O3Pureza:98%Forma y color:SolidPeso molecular:538.56Retaspimycin Hydrochloride
CAS:Retaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).Fórmula:C31H46ClN3O8Pureza:98%Forma y color:SolidPeso molecular:624.17Anticancer agent 48
CAS:<p>Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.</p>Fórmula:C26H25N3O4Forma y color:SolidPeso molecular:443.49CAY10701
CAS:CAY10701, a 7-deazahypoxanthine, impedes cell growth (GI50: 9-38 nM) while sparing normal fibroblasts (>1,500-fold), and shrinks mouse colorectal tumors.Fórmula:C24H19N3O2Forma y color:SolidPeso molecular:381.43ME-143
CAS:ME-143, a 2nd-gen NADH oxidase inhibitor, blocks WNT/β-catenin pathway, active against various cancers in vitro/vivo.Fórmula:C21H18O4Forma y color:SolidPeso molecular:334.37GR 144053 trihydrochloride
CAS:<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Fórmula:C18H30Cl3N5O2Pureza:98%Forma y color:SolidPeso molecular:454.82EMD534085
CAS:<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Fórmula:C25H31F3N4O2Pureza:98%Forma y color:SolidPeso molecular:476.536BrCaQ
CAS:<p>6BrCaQ inhibits TRAP1, has antiproliferative effects, and is used in 6BrCaQ-TPP synthesis.</p>Fórmula:C18H15BrN2O3Forma y color:SolidPeso molecular:387.23MPC-3100
CAS:<p>MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1].</p>Fórmula:C22H25BrN6O4SForma y color:SolidPeso molecular:549.44Tau-aggregation-IN-1
CAS:Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).Fórmula:C28H37N5O2SForma y color:SolidPeso molecular:507.69Hydromethylthionine HBr
CAS:<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Fórmula:C16H21Br2N3SForma y color:SolidPeso molecular:447.233Ellipticine quinone
CAS:Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.Fórmula:C15H8N2O2Forma y color:SolidPeso molecular:248.24MK-0668 Mesylate
CAS:MK-0668 Mesylate is the mesylate form of MK-0668 that is a very potent and orally active very late antigen-4 antagonist.Fórmula:C32H34Cl2N6O9S2Forma y color:SolidPeso molecular:781.68Tubulin polymerization-IN-7
CAS:<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Fórmula:C28H24N4O6SForma y color:SolidPeso molecular:544.58NC043
CAS:NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.Fórmula:C20H26O4Pureza:98%Forma y color:SolidPeso molecular:330.42S-methyl DM1
CAS:S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Fórmula:C36H50ClN3O10SPureza:98%Forma y color:SolidPeso molecular:752.31Tubulin polymerization-IN-39
<p>Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.</p>Fórmula:C21H21N5O5Forma y color:SolidPeso molecular:423.42
