Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1381 productos de "Señalización citoesquelética"
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JG-231
CAS:<p>JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.</p>Fórmula:C22H18BrCl2N3OS4Pureza:99.79%Forma y color:SolidPeso molecular:619.47BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Fórmula:C18H15BrCl2N2O2Pureza:99.93%Forma y color:SolidPeso molecular:442.13AMP-PCP disodium
CAS:AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM.Fórmula:C11H16N5Na2O12P3Pureza:99.32% - 99.32%Forma y color:SolidPeso molecular:549.17Nilotinib hydrochloride
CAS:<p>Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.</p>Fórmula:C28H23ClF3N7OPureza:>99.99%Forma y color:SolidPeso molecular:565.98EMT inhibitor-1
CAS:<p>EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.</p>Fórmula:C12H12Cl2N2O2SPureza:99.53%Forma y color:SolidPeso molecular:319.21JH-VIII-157-02
CAS:<p>JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.</p>Fórmula:C28H27N5O2Pureza:99.58%Forma y color:SolidPeso molecular:465.55AKT-IN-6
CAS:<p>AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.</p>Fórmula:C22H20FN5OPureza:98.68%Forma y color:SolidPeso molecular:389.43Erbulozole
CAS:<p>Erbulozole (R 55104) is a synthetic microtubule inhibitor with anti-invasive activity that induces Wernicke's encephalopathy-like neurotoxicity.</p>Fórmula:C24H27N3O5SPureza:99.88%Forma y color:SolidPeso molecular:469.55JB061
<p>JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle</p>Fórmula:C19H17NO4Pureza:99.67%Forma y color:SoildPeso molecular:323.34Dynapyrazole A
CAS:<p>Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).</p>Fórmula:C20H12ClIN4OPureza:98.01%Forma y color:SolidPeso molecular:486.69Arimoclomol
CAS:<p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>Fórmula:C14H20ClN3O3Pureza:99.15%Forma y color:SolidPeso molecular:313.78JB002
CAS:<p>JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM.</p>Fórmula:C18H15NO3Pureza:99.74%Forma y color:SoildPeso molecular:293.32CID-663143
CAS:<p>CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.</p>Fórmula:C19H18N4O2SPureza:99.68% - 99.77%Forma y color:SolidPeso molecular:366.44Defactinib hydrochloride
CAS:<p>Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.</p>Fórmula:C20H22ClF3N8O3SPureza:98.06% - 98.78%Forma y color:SolidPeso molecular:546.95TCS 2210
CAS:<p>TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.</p>Fórmula:C18H17N3O3Pureza:98.62%Forma y color:SolidPeso molecular:323.35SB-216
CAS:<p>SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.</p>Fórmula:C17H18N4O2Pureza:99.70%Forma y color:SolidPeso molecular:310.35para-Nitroblebbistatin
CAS:<p>para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.</p>Fórmula:C18H15N3O4Pureza:99.09% - 99.84%Forma y color:SolidPeso molecular:337.33Porcn-IN-2
CAS:<p>Porcn-IN-2 (Example 107) is a potent Wnt pathway inhibitor, exhibiting an IC50 of 0.05 nM.</p>Fórmula:C24H17F3N6OForma y color:SolidPeso molecular:462.43CNS-11
CAS:<p>CNS-11, a compound that disaggregates tau fibrils, is utilized in Alzheimer's disease (AD) research [1].</p>Fórmula:C25H21N3O2Forma y color:SolidPeso molecular:395.45MC-Val-Cit-PAB-Ispinesib
CAS:<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Fórmula:C59H71ClN10O10Forma y color:SolidPeso molecular:1115.71
