Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1381 productos de "Señalización citoesquelética"
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Oxaline
CAS:<p>Oxaline, a fungal alkaloid derived from Penicillium oxalicum, impedes tubulin polymerization, leading to cell cycle arrest at the M phase [1] [2].</p>Fórmula:C24H25N5O4Forma y color:SolidPeso molecular:447.49Tubulin polymerization-IN-52
CAS:<p>Tubulin polymerization-IN-52 (compound SC23) effectively inhibits tubulin polymerization, exhibiting an IC50 value of 2.9 μM [1].</p>Fórmula:C21H18F3N5O3Forma y color:SolidPeso molecular:445.39Risvodetinib
CAS:<p>Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.</p>Fórmula:C33H34N8O2Forma y color:SolidPeso molecular:574.68Solitomab
CAS:<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Forma y color:LiquidTubulin inhibitor 25
CAS:<p>Potent Tubulin inhibitor 25: IC50 0.98 μM, blocks HT29 cell growth, hinders cell migration & microtubule formation, anti-angiogenic.</p>Fórmula:C26H22O8Forma y color:SolidPeso molecular:462.45β-Catenin modulator-4
CAS:<p>β-Catenin modulator-4 (compound IIa-92), encompassing oxazole and thiazole moieties, acts as a potent and selective modulator of β-Catenin [1].</p>Fórmula:C21H21ClN2O2SForma y color:SolidPeso molecular:400.92KIF18A-IN-7
CAS:<p>KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent</p>Fórmula:C27H35N3O5S2Forma y color:SoildPeso molecular:545.71EG-011
CAS:<p>EG-011, a potent first-in-class WASP activator, enhances actin polymerization, showing selective anti-tumor effects in lymphomas.</p>Fórmula:C28H26N4O4Forma y color:SolidPeso molecular:482.53TCS 21311
CAS:<p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.</p>Fórmula:C27H25F3N4O4Pureza:99.39% - ≥98%Forma y color:SolidPeso molecular:526.51αvβ1 integrin-IN-2
CAS:<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Fórmula:C29H38N4O4Pureza:98%Forma y color:SolidPeso molecular:506.64Gly-Arg-Gly-Asp-Ser TFA
CAS:<p>Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.</p>Fórmula:C19H31F3N8O11Forma y color:SolidPeso molecular:604.49Pin1 modulator 1
CAS:<p>Pin1 modulator 1 (compound IIb-219) is a specific β-Catenin targeting agent that inhibits the Wnt pathway and is applicable in researching Wnt-mediated diseases, including cancer [1].</p>Fórmula:C18H15NO3S2Forma y color:SolidPeso molecular:357.44BX-2819
CAS:<p>BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .</p>Fórmula:C21H24N4O4SPureza:98%Forma y color:SolidPeso molecular:428.51WAY 316606 hydrochloride
CAS:<p>WAY 316606 hydrochloride is a chemical compound that serves as an inhibitor of sFRP-1 (secreted protein), which functions as an endogenous antagonist of the Wnt (secreted glycoprotein). Its affinity for sFRP-1 is measured through the FP (fluorescence polarization) binding assay, revealing an IC50 (half maximal inhibitory concentration) of 0.5 μM [1].</p>Fórmula:C18H20ClF3N2O4S2Forma y color:SolidPeso molecular:484.94KSP-IA
CAS:<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Fórmula:C21H22F2N2OPureza:98%Forma y color:SolidPeso molecular:356.41Kif15-IN-2
CAS:<p>Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.</p>Fórmula:C20H20N6O4SPureza:98.17%Forma y color:SolidPeso molecular:440.48VTX-27
CAS:VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).Fórmula:C20H24ClFN6OPureza:99.84%Forma y color:SolidPeso molecular:418.9BIO-7662
CAS:BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.Fórmula:C38H48N6O8SPureza:98%Forma y color:SolidPeso molecular:748.89Demethylasterriquinone B1
CAS:<p>insulin receptor (IR) activator</p>Fórmula:C32H30N2O4Pureza:98%Forma y color:SolidPeso molecular:506.59Pterostilbene-isothiocyanate
CAS:<p>Pterostilbene-isothiocyanate (PTER-ITC) demonstrates strong anticancer properties in vitro, particularly disrupting the interaction between β-catenin and TCF-4</p>Fórmula:C18H19N3O3SForma y color:SolidPeso molecular:357.43
