Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1384 productos de "Señalización citoesquelética"
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β-catenin-IN-6
CAS:<p>β-Catenin-IN-6 is an inhibitor of the canonical Wnt/β-catenin signaling pathway, effectively impeding the proliferation of human colorectal cancer cells and</p>Fórmula:C22H19ClN6OForma y color:SolidPeso molecular:418.88CT-721
CAS:<p>CT-721: potent, time-bound Bcr-Abl inhibitor, IC50 21.3 nM, effective against CML.</p>Fórmula:C30H29ClN6OPureza:98%Forma y color:SolidPeso molecular:525.04BIO-7662
CAS:<p>BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.</p>Fórmula:C38H48N6O8SPureza:98%Forma y color:SolidPeso molecular:748.89HSP90-IN-27
CAS:<p>HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].</p>Fórmula:C18H21N3O2SPureza:98%Forma y color:SolidPeso molecular:343.44Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2
CAS:<p>Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 demonstrates serum stability and non-toxicity to neuronal cells, while selectively inhibiting the fibrilization of tau in</p>Fórmula:C38H65N11O9Forma y color:SolidPeso molecular:819.99WAY 316606 hydrochloride
CAS:<p>WAY 316606 hydrochloride is a chemical compound that serves as an inhibitor of sFRP-1 (secreted protein), which functions as an endogenous antagonist of the Wnt (secreted glycoprotein). Its affinity for sFRP-1 is measured through the FP (fluorescence polarization) binding assay, revealing an IC50 (half maximal inhibitory concentration) of 0.5 μM [1].</p>Fórmula:C18H20ClF3N2O4S2Forma y color:SolidPeso molecular:484.94AKT-IN-13
CAS:<p>AKT-IN-13 inhibits Akt1, Akt2, Akt3 (IC50: 1.6, 2.4, 0.3 nM); used in cancer research.</p>Fórmula:C24H31ClN6O2Forma y color:SolidPeso molecular:470.99Ifebemtinib
CAS:<p>Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.</p>Fórmula:C28H28F4N6O4Pureza:98.84% - 99.85%Forma y color:SolidPeso molecular:588.55Zamaporvint
CAS:<p>Zamaporvint (RXC004) , a Wnt pathway inhibitor with antitumor and antiproliferative activity, blocks Wnt ligand palmitoylation and secretion.</p>Fórmula:C21H16F3N7OPureza:97.5%Forma y color:SolidPeso molecular:439.39Gossypolone
CAS:<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Fórmula:C30H26O10Pureza:96.66%Forma y color:SolidPeso molecular:546.52UCL-TRO-1938
CAS:<p>UCL-TRO-1938 is a subtype-selective PI3Kα allosteric activator with cardioprotective and neuroregenerative effects.</p>Fórmula:C27H32N6OPureza:99.95%Forma y color:SolidPeso molecular:456.58M2698
CAS:<p>M2698 (MSC2363318A) is an inhibitor of p70S6K, Akt1 and Akt3 with IC50s of 1 nM. M2698 shows anti-cancer activity.</p>Fórmula:C21H19ClF3N5OPureza:99.88%Forma y color:SolidPeso molecular:449.86Roxifiban acetate
CAS:<p>Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used in</p>Fórmula:C23H33N5O8Pureza:97.91% - 98.36%Forma y color:SolidPeso molecular:507.54CFI-402257
CAS:<p>CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.</p>Fórmula:C28H30N6O3Pureza:96.66% - 99.51%Forma y color:SolidPeso molecular:498.58αvβ1 integrin-IN-1
CAS:<p>αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.</p>Fórmula:C26H34N6O6SPureza:99.74% - >99.99%Forma y color:SolidPeso molecular:558.65ATM-3507
CAS:<p>ATM-3507 is an inhibitor of tropomyosin. In human melanoma cell lines, the IC50s are from 3.83-6.84 μM.</p>Fórmula:C37H46FN5O2Pureza:96.77% - 98.81%Forma y color:SolidPeso molecular:611.79GNF-6231
CAS:<p>GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.</p>Fórmula:C24H25FN6O2Pureza:99.74% - >99.99%Forma y color:SolidPeso molecular:448.49PKC-IN-1
CAS:PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,Fórmula:C25H37FN8O2Pureza:98% - 98.79%Forma y color:SolidPeso molecular:500.61PM-060184
CAS:<p>PM-060184, a tubulin polymerisation inhibitor, is used potentially for the treatment of solid tumours and breast cancer.</p>Fórmula:C31H45N3O7Pureza:98%Forma y color:SolidPeso molecular:571.7Dictyostatin
CAS:<p>Dictyostatin: potent microtubule stabilizer & anticancer agent with antiproliferative effects; researched for tauopathies.</p>Fórmula:C32H52O6Forma y color:SolidPeso molecular:532.75
