Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1382 productos de "Señalización citoesquelética"
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Pre-084
CAS:<p>Pre-084 is a high affinity, selective σ1 agonist.</p>Fórmula:C19H28ClNO3Pureza:99.91%Forma y color:SolidPeso molecular:353.88Shepherdin 79-87 acetate
<p>Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.</p>Fórmula:C43H68N12O14SPureza:98.08%Forma y color:SolidPeso molecular:1009.14AZ13705339 hemihydrate
<p>AZ13705339 hemihydrate: potent PAK1 inhibitor (IC50: 0.33 nM), also binds PAK1/2 (Kd: 0.28/0.32 nM), for cancer research.</p>Fórmula:C33H36FN7O3SH2OForma y color:SolidPeso molecular:638.77Bexotegrast
CAS:<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Fórmula:C27H36N6O3Pureza:99.53%Forma y color:SolidPeso molecular:492.61Alvespimycin
CAS:<p>Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.</p>Fórmula:C32H48N4O8Pureza:99.88%Forma y color:SolidPeso molecular:616.75FAK activator 1
CAS:<p>ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.</p>Fórmula:C23H26F3N3O3Pureza:99.19%Forma y color:SoildPeso molecular:449.47RO0270608
CAS:<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Fórmula:C24H19Cl3N2O4Pureza:98.26%Forma y color:SolidPeso molecular:505.78Muromonab
CAS:<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Pureza:95% - 97.51% (SEC-HPLC)Forma y color:LiquidNeurodazine
CAS:<p>Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.</p>Fórmula:C27H21ClN2O3Pureza:98.01%Forma y color:SolidPeso molecular:456.92Bosutinib hydrate
CAS:<p>Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.</p>Fórmula:C26H31Cl2N5O4Pureza:99.87%Forma y color:SolidPeso molecular:548.46Etaracizumab
CAS:<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Pureza:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.3 (kDa)Vevorisertib trihydrochloride
CAS:<p>Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is ainhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3.</p>Fórmula:C35H41Cl3N8OPureza:98.28%Forma y color:SolidPeso molecular:696.12Ruboxistaurin hydrochloride
CAS:<p>Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.</p>Fórmula:C28H28N4O3·HClPureza:98.44% - 99.22%Forma y color:SolidPeso molecular:505.01H-Ile-Lys-Val-Ala-Val-OH
CAS:<p>H-Ile-Lys-Val-Ala-Val-OH can induce rapid differentiation of neural progenitor cells into neurons and neurite growth.</p>Fórmula:C25H48N6O6Pureza:99.92%Forma y color:SolidPeso molecular:528.69Arg-Gly-Asp-Ser
CAS:<p>Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.</p>Fórmula:C15H27N7O8Pureza:98.29%Forma y color:SolidPeso molecular:433.42NQTrp
CAS:<p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>Fórmula:C21H16N2O4Pureza:98.35%Forma y color:SolidPeso molecular:360.36Mps1-IN-2
CAS:<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Forma y color:SolidPeso molecular:480.6WZU-13
CAS:<p>WZU-13 is an inhibitor of carboxylesterase (CES). At a concentration of 100 μM, WZU-13 suppresses 77% of CES activity.</p>Fórmula:C22H16N2OForma y color:SolidPeso molecular:324.38Anti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Pureza:99%Forma y color:Odour LiquidST-401
CAS:<p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>Fórmula:C24H20N2OForma y color:SolidPeso molecular:352.43Vepsitamab
CAS:<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Forma y color:LiquidPinatuzumab
CAS:<p>Pinatuzumab is a humanised monoclonal antibody targeting CD22, B-cell malignancies non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukaemia (CLL).</p>Pureza:95%Forma y color:LiquidPasotuxizumab
CAS:<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Forma y color:LiquidTepoditamab
CAS:<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Forma y color:LiquidGresonitamab
CAS:<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Forma y color:LiquidObrindatamab
CAS:<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Forma y color:LiquidEnlimomab
CAS:<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Forma y color:LiquidNivatrotamab
<p>Nivatrotamab: Humanized anti-GD2/CD3 bispecific antibody for neuroblastoma research.</p>Forma y color:Odour LiquidSemorinemab
CAS:<p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>Pureza:95% - 95%Forma y color:Liquid4-Desacetylvinblastine hydrazide
CAS:<p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>Fórmula:C43H56N6O7Forma y color:SolidPeso molecular:768.94Raludotatug
CAS:<p>Raludotatug is a humanized antibody targeting cadherin-6 (CDH6). As part of the ADC Raludotatug deruxtecan, it shows promise in researching platinum-sensitive ovarian cancer.</p>Pureza:95% - 95%Forma y color:LiquidGosuranemab
CAS:<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Pureza:95% - 95%Forma y color:LiquidMeclofenamate sodium hydrate
CAS:<p>Meclofenamate sodium: a strong NSAID inhibiting leukocyte function—chemotaxis, degranulation, and radical production.</p>Fórmula:C14H12Cl2NNaO3Forma y color:SolidPeso molecular:336.15Posdinemab
CAS:<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Forma y color:LiquidPlamotamab
CAS:<p>Plamotamab (XmAb-13676) is a bispecific antibody targeting CD3 and CD20, recruiting T cells to destroy CD20+ tumors and causing mild hematologic reactions.</p>Forma y color:LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Pureza:98%Forma y color:Odour LiquidUbamatamab
CAS:<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Forma y color:LiquidOsemitamab
CAS:<p>Osemitamab (TST001) is a humanised monoclonal antibody targeting claudin-18.2, gastric/gastric-oesophageal junction adenocarcinoma, PDAC, and lung cancer.</p>Pureza:95%Forma y color:LiquidVoxalatamab
CAS:<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Forma y color:LiquidVonsetamig
CAS:<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Forma y color:LiquidFlotetuzumab
CAS:<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Forma y color:LiquidPacanalotamab
CAS:<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Forma y color:LiquidVibecotamab
CAS:<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Forma y color:LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Pureza:95%Forma y color:Odour LiquidRovelizumab
CAS:<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Forma y color:LiquidLixudebart
CAS:<p>Lixudebart is a humanised monoclonal antibody targeting CLDN1 (Claudin-1), which can be used to reverse organ fibrosis and reduce initial ALT/AST levels.</p>Pureza:95%Forma y color:LiquidVatelizumab
CAS:<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Pureza:95%Forma y color:LiquidLinvoseltamab
CAS:<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Forma y color:LiquidCevostamab
CAS:<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Forma y color:LiquidOdronextamab
CAS:<p>Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].</p>Forma y color:LiquidPavurutamab
CAS:<p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>Forma y color:Liquid17-AEP-GA
CAS:<p>17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.</p>Fórmula:C34H50N4O8Pureza:97.77% - 99.56%Forma y color:SolidPeso molecular:642.78Tubulin polymerization-IN-2
CAS:<p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>Fórmula:C17H12F2N2O2Forma y color:SolidPeso molecular:314.29Meclofenamic acid
CAS:<p>Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.</p>Fórmula:C14H11Cl2NO2Pureza:98%Forma y color:SolidPeso molecular:296.15SB273005
CAS:<p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>Fórmula:C22H24F3N3O4Pureza:99.58%Forma y color:SolidPeso molecular:451.44N-Desmethylnefopam
CAS:<p>N-Desmethylnefopam is the main Nefopam metabolite .</p>Fórmula:C16H17NOPureza:98%Forma y color:SolidPeso molecular:239.31Ionomycin calcium
CAS:<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Fórmula:C41H70CaO9Pureza:98% - 98.11%Forma y color:SolidPeso molecular:747.07Phorbol 12,13-dibutyrate
CAS:<p>Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.</p>Fórmula:C28H40O8Pureza:99.32% - 99.37%Forma y color:SolidPeso molecular:504.61D-GsMTx4 TFA
<p>D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective stretch-activated channels (SACs), and attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglia reactivity. toxicity and microglia reactivity.D-GsMTx4 TFA prevented myocardial infarction in a mouse model of ischemia/reperfusion and can be used to characterize the role of excitatory MSCs in normal physiology and pathology.</p>Fórmula:C187H279F3N48O48S6Pureza:99.29% - 99.65%Forma y color:SoildPeso molecular:4216.93IPA-3
CAS:<p>IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).</p>Fórmula:C20H14O2S2Pureza:97.40%Forma y color:SolidPeso molecular:350.45Tirofiban
CAS:<p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>Fórmula:C22H36N2O5SPureza:99.83%Forma y color:SolidPeso molecular:440.6Auristatin F
CAS:<p>Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.</p>Fórmula:C40H67N5O8Pureza:98.41% - 99.25%Forma y color:SolidPeso molecular:745.99Mps1-IN-1
CAS:<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Fórmula:C28H33N5O4SPureza:98.33%Forma y color:SolidPeso molecular:535.66BAY1217389
CAS:<p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).</p>Fórmula:C27H24F5N5O3Pureza:98.14% - 99.42%Forma y color:SolidPeso molecular:561.5AS1938909
CAS:<p>AS1938909: SHIP2 inhibitor boosts Akt phosphorylation, glucose use, and uptake via GLUT1 in L6 myotubes.</p>Fórmula:C19H13Cl2F2NO2SPureza:98%Forma y color:SolidPeso molecular:428.28IQTub4P
CAS:<p>IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).</p>Fórmula:C19H18NNa2O8PForma y color:SolidPeso molecular:465.305HSP90-IN-14
CAS:<p>HSP90-IN-14 inhibits Hsp90 (Kd=0.26 μM) and fights influenza A/H3N2, A/H1N1, B with EC50 of 2.6, 3.9, 17 μM in MDCK cells.</p>Fórmula:C14H8Cl2N4O4SForma y color:SolidPeso molecular:399.21Microtubule inhibitor 4
CAS:<p>Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).</p>Fórmula:C25H23FN4O3Forma y color:SolidPeso molecular:446.47NC9 TG2 inhibitor
CAS:<p>NC9 is an irreversible inhibitor of transglutaminase 2 (TG2) and also inhibits Factor XIIIA (FXIIIA).</p>Fórmula:C35H47N5O8SPureza:98%Forma y color:SolidPeso molecular:697.84Antiproliferative agent-30
CAS:<p>Antiproliferative agent-30 (Compound 8g) demonstrates broad-spectrum antiproliferative activity, with IC50 values of 0.054 nM, 0.008 nM, and 0.144 nM against</p>Fórmula:C24H26N4O4Forma y color:SolidPeso molecular:434.49Tubulin polymerization-IN-42
CAS:<p>Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].</p>Fórmula:C22H21NO5Forma y color:SolidPeso molecular:379.41CCT251236
CAS:<p>CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.</p>Fórmula:C32H32N4O5Pureza:98.82% - 99.89%Forma y color:SolidPeso molecular:552.62GR 144053 trihydrochloride
CAS:<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Fórmula:C18H30Cl3N5O2Pureza:98%Forma y color:SolidPeso molecular:454.82Alyssin
CAS:<p>Alyssin: sulforaphane analog, antioxidant; boosts Nrf2 and phase II enzymes in cancer cells; lowers PAH metabolism, reducing cancer risk in vitro.</p>Fórmula:C7H13NOS2Pureza:98%Forma y color:SolidPeso molecular:191.31CH5164840
CAS:<p>CH5164840: strong HSP90 blocker; excels in NSCLC treatment; boosts erlotinib efficacy on EGFR-mutant tumors.</p>Fórmula:C19H23N5O2SForma y color:SolidPeso molecular:385.48Tubulozole
CAS:<p>Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.</p>Fórmula:C23H23Cl2N3O4SPureza:98%Forma y color:SolidPeso molecular:508.42SEW84
CAS:<p>SEW84, an Aha1-stimulated Hsp90 inhibitor, has an IC50 of 0.3 μM, aiding protein deposition disease research.</p>Fórmula:C19H14F4N4OSForma y color:SolidPeso molecular:422.4Hsp90-Cdc37-IN-1
CAS:<p>Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.</p>Fórmula:C43H57FN2O6SPureza:98%Forma y color:SolidPeso molecular:748.99PP2A Cancerous-IN-1
CAS:<p>PP2A Cancerous-IN-1 is a potent inhibitor of CIP2A (Cancerous inhibitor of PP2A) and p-Akt that exhibits potent anti-proliferative effects.</p>Fórmula:C30H24N4O3Forma y color:SolidPeso molecular:488.54OXi8007
CAS:<p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>Fórmula:C26H24NNa2O10PForma y color:SolidPeso molecular:587.428Hsp90-IN-17
CAS:<p>Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.</p>Fórmula:C21H20N4O7Forma y color:SolidPeso molecular:440.41Chrysotobibenzyl
CAS:<p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>Fórmula:C19H24O5Forma y color:SolidPeso molecular:332.39Hydromethylthionine HBr
CAS:<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Fórmula:C16H21Br2N3SForma y color:SolidPeso molecular:447.233CHPG
CAS:<p>CHPG is a selective mGluR5 agonist protects against traumatic brain injury.activates the ERK and Akt pathways, It also alleviates LPS-induced inflammation.</p>Fórmula:C8H8ClNO3Pureza:98%Forma y color:SolidPeso molecular:201.61Heat Shock Protein Inhibitor II
CAS:<p>Hsp inhibitor II, an active benzylidene lactam, blocks inducible Hsp synthesis, reduces tumor thermotolerance, and enhances AmB effects on A. fumigatus.</p>Fórmula:C12H11NO3Forma y color:SolidPeso molecular:217.22Tau-aggregation-IN-1
CAS:<p>Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).</p>Fórmula:C28H37N5O2SForma y color:SolidPeso molecular:507.69AK963
CAS:<p>AK963 (40708899) is a powerful PAK1 inhibitor reducing gastric cancer cell growth via the PAK1-NFκB-CyclinB1 pathway.</p>Fórmula:C16H18N2OForma y color:SolidPeso molecular:254.33(R)-TTBK1-IN-1
CAS:<p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.</p>Fórmula:C18H19N5O2Forma y color:SolidPeso molecular:337.38BMS-688521
CAS:<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Fórmula:C26H19Cl2N5O4Pureza:98.87%Forma y color:SolidPeso molecular:536.37Syntelin
CAS:<p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>Fórmula:C21H20N6O2S3Forma y color:SolidPeso molecular:484.62LS-104
CAS:<p>LS-104 is a JAK2 inhibitor.</p>Fórmula:C19H16N2O3Forma y color:SolidPeso molecular:320.34Tubulin polymerization-IN-25
CAS:<p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>Fórmula:C24H18N2O3SForma y color:SolidPeso molecular:414.48AKT-IN-8
CAS:<p>AKT-IN-8 is a potent inhibitor of AKT, acting on AKT1 (IC50: 4.46 nM), AKT2 (IC50: 2.44 nM) and AKT3 (IC50: 9.47 nM).</p>Fórmula:C22H25ClN6O3Forma y color:SolidPeso molecular:456.93AKT-IN-5
CAS:<p>AKT-IN-5, an Akt inhibitor, targets Akt1/Akt2 with IC50s: 450/400 nM.</p>Fórmula:C23H20N4O2Forma y color:SolidPeso molecular:384.43Zalunfiban
CAS:<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Fórmula:C16H18N8O2SForma y color:SolidPeso molecular:386.43cemadotin free base
CAS:<p>Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks</p>Fórmula:C35H56N6O5Pureza:98.70% - 99.64%Forma y color:SolidPeso molecular:640.86Zarilamide
CAS:<p>Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.</p>Fórmula:C11H11ClN2O2Forma y color:SolidPeso molecular:238.67Tubulin polymerization-IN-20
CAS:<p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>Fórmula:C25H24FNO5Forma y color:SolidPeso molecular:437.46Tubulin/MMP-IN-1
<p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>Fórmula:C38H44NO9PForma y color:SolidPeso molecular:689.73HSP90-IN-20
CAS:<p>HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.</p>Fórmula:C26H32N4O4Forma y color:SolidPeso molecular:464.56Tubulin inhibitor 12
CAS:<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Fórmula:C24H20N2OForma y color:SolidPeso molecular:352.43BCR-ABL1-IN-1
CAS:<p>BCR-ABL1-IN-1: potent, orally active ABL kinase inhibitor with high specificity, promising for CNS research.</p>Fórmula:C18H12F3N3O2Forma y color:SolidPeso molecular:359.3KY-04031
CAS:<p>KY-04031 is an inhibitor of p21-activated kinase 4.</p>Fórmula:C21H20N8OForma y color:SolidPeso molecular:400.44AFG210
CAS:<p>AFG210 is a novel first-generation “type II” FLT3 inhibitor.</p>Fórmula:C19H14F3N3O2Forma y color:SolidPeso molecular:373.33BCR-ABL-IN-5
CAS:<p>BCR-ABL-IN-5: Bcr-Abl kinase inhibitor, IC50: Bcr-AblWT 0.014 μM, Bcr-AblT315I 0.45 μM; anti-leukemia cell growth.</p>Fórmula:C25H21Cl2N5O2Forma y color:SolidPeso molecular:494.37Iso-Fludelone
CAS:<p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>Fórmula:C27H36F3NO6Forma y color:SolidPeso molecular:527.5710-DEBC hydrochloride
CAS:<p>10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2].</p>Fórmula:C20H26Cl2N2OForma y color:SolidPeso molecular:381.34DRP1i27
CAS:<p>DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.</p>Fórmula:C20H26N6OForma y color:SolidPeso molecular:366.46KY-04045
CAS:<p>KY-04045 is a PAK4 inhibitor.</p>Fórmula:C13H14BrN5Forma y color:SolidPeso molecular:320.19NAMI-A
CAS:<p>NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.</p>Fórmula:C8H15Cl4N4ORuSPureza:98%Forma y color:SolidPeso molecular:458.18SSTC3
CAS:<p>SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.</p>Fórmula:C23H17F3N4O3S2Pureza:98.65% - 99.94%Forma y color:SolidPeso molecular:518.53CHMFL-ABL-053
CAS:<p>CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.</p>Fórmula:C28H26F3N7O2Forma y color:SolidPeso molecular:549.55BuChE-IN-5
CAS:<p>"BuChE-IN-5 is a potent inhibitor with an IC50 of 1.94 μM and shows promise for Alzheimer's research."</p>Fórmula:C25H35N3Forma y color:SolidPeso molecular:377.57Microtubule inhibitor 5
CAS:<p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>Fórmula:C22H15FN2O4Forma y color:SolidPeso molecular:390.36AJH-836
CAS:<p>AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of</p>Fórmula:C22H38O5Pureza:98%Forma y color:SolidPeso molecular:382.53Tubulin inhibitor 27
CAS:<p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>Fórmula:C21H19NO4Forma y color:SolidPeso molecular:349.38Tubulin polymerization-IN-10
CAS:<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Fórmula:C18H21NO6SForma y color:SolidPeso molecular:379.43HSP90-IN-22
CAS:<p>HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in</p>Fórmula:C25H30N4O3Pureza:98%Forma y color:SolidPeso molecular:434.53YM-1
CAS:<p>YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.</p>Fórmula:C20H20ClN3OS2Forma y color:SolidPeso molecular:417.98Sibrafiban
CAS:<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Fórmula:C20H28N4O6Forma y color:SolidPeso molecular:420.46Neuroinflammatory-IN-3
CAS:<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Fórmula:C19H19ClO3Forma y color:SolidPeso molecular:330.81Tubulin polymerization-IN-36
CAS:<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Fórmula:C18H18N2O3Forma y color:SolidPeso molecular:310.35Tubulin polymerization-IN-16
CAS:<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Fórmula:C24H27N5O5Forma y color:SolidPeso molecular:465.5BCR-ABL-IN-6
CAS:<p>BCR-ABL-IN-6, an imatinib derivative, inhibits Bcr-AblWT (4.6 nM IC50) and T315I (277 nM), for chronic myeloid leukemia study.</p>Fórmula:C27H22F3N5O2Forma y color:SolidPeso molecular:505.49Retaspimycin
CAS:<p>Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).</p>Fórmula:C31H45N3O8Pureza:98%Forma y color:SolidPeso molecular:587.7Tubulin polymerization-IN-15
CAS:<p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>Fórmula:C18H17N3O4Forma y color:SolidPeso molecular:339.35Tubulin inhibitor 18
CAS:<p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>Fórmula:C22H26O5Forma y color:SolidPeso molecular:370.44Tubulin polymerization-IN-18
CAS:<p>Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.</p>Fórmula:C25H25NO6Forma y color:SolidPeso molecular:435.47GNF-1331
CAS:<p>GNF-1331: potent, selective oral porcupine inhibitor; IC50=12 nM; targets aberrant Wnt signaling in cancers.</p>Fórmula:C20H20N6O2S2Forma y color:SolidPeso molecular:440.54Synstab A
CAS:<p>Synstab A is a microtubule stabilizer.</p>Fórmula:C15H13BrCl3N3O3SForma y color:SolidPeso molecular:501.61KUNB31
CAS:<p>KUNB31 is a potent and selective inhibitor of Hsp90β.</p>Fórmula:C19H18N2O3Forma y color:SolidPeso molecular:322.36Microtubule inhibitor 7
CAS:<p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>Fórmula:C25H19FN2O5Forma y color:SolidPeso molecular:446.43(S)-Dolaphenine hydrochloride
CAS:<p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>Fórmula:C11H13ClN2SPureza:98%Forma y color:SolidPeso molecular:240.75Dihydrocytochalasin B
CAS:<p>Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.</p>Fórmula:C29H39NO5Pureza:98%Forma y color:SolidPeso molecular:481.62MK-0668
CAS:<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Fórmula:C31H30Cl2N6O6SForma y color:SolidPeso molecular:685.58Tau tracer 1
CAS:<p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>Fórmula:C34H23N5O2Forma y color:SolidPeso molecular:533.591Deox B 7,4
CAS:<p>Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.</p>Fórmula:C18H18O5Forma y color:SolidPeso molecular:314.33SW02
CAS:<p>SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).</p>Fórmula:C19H23BrN2O5Forma y color:SolidPeso molecular:439.3Tubulin polymerization-IN-30
CAS:<p>Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.</p>Fórmula:C22H25N5O3Forma y color:SolidPeso molecular:407.47Tubulin inhibitor 29
CAS:<p>Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.</p>Fórmula:C12H8F2O2S2Forma y color:SolidPeso molecular:286.32Microtubule inhibitor 6
CAS:<p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>Fórmula:C24H19FN2O5Forma y color:SolidPeso molecular:434.42Tubulin inhibitor 31
<p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>Fórmula:C22H19NO2Forma y color:SolidPeso molecular:329.39BCR-ABL-IN-1
CAS:<p>BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.</p>Fórmula:C23H21F4N5OPureza:98%Forma y color:SolidPeso molecular:459.44PD-173956
CAS:<p>PD-173956 is an inhibitor of the Src family tyrosine kinases.</p>Fórmula:C20H13Cl2FN4OForma y color:SolidPeso molecular:415.25Tubulin polymerization-IN-7
CAS:<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Fórmula:C28H24N4O6SForma y color:SolidPeso molecular:544.58PF-06651481-00
CAS:<p>PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.</p>Fórmula:C26H29Cl2N5O3Pureza:97.01%Forma y color:SolidPeso molecular:530.45β-glycosidase-IN-1
CAS:<p>β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.</p>Fórmula:C13H23NO5Pureza:98%Forma y color:SolidPeso molecular:273.33TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Fórmula:C28H34N4O6Pureza:98%Forma y color:SolidPeso molecular:522.59Anticancer agent 60
CAS:<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Fórmula:C27H33N5O4SForma y color:SolidPeso molecular:523.65Cevipabulin
CAS:<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Fórmula:C18H18ClF5N6OPureza:99.53%Forma y color:SolidPeso molecular:464.82Mps-BAY2b
CAS:<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Fórmula:C20H23N5OForma y color:SolidPeso molecular:349.43Mps1-IN-4
CAS:<p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>Fórmula:C26H31F3N6O2Forma y color:SolidPeso molecular:516.56AP 24149
CAS:<p>AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.</p>Fórmula:C23H24N5OPForma y color:SolidPeso molecular:417.44SB26019
CAS:<p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>Fórmula:C24H20O4Forma y color:SolidPeso molecular:372.41YW1159
CAS:<p>YW1159 is an inhibitor of Wnt signaling.</p>Fórmula:C19H14FN5OForma y color:SolidPeso molecular:347.35AMXI-5001
CAS:<p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>Fórmula:C25H20FN5O3Forma y color:SolidPeso molecular:457.46Tubulin polymerization-IN-21
CAS:<p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>Fórmula:C30H29NO7Forma y color:SolidPeso molecular:515.55AM-9635
CAS:<p>AM-9635: Potent PI3Kδ inhibitor, cellular IC50 4.2 nM, reduces IgG/IgM, well-tolerated, affects cell growth/division.</p>Fórmula:C19H14F2N8Forma y color:SolidPeso molecular:392.36Clathrin-IN-2
CAS:<p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>Fórmula:C17H18Br2N2OForma y color:SolidPeso molecular:426.15Tubulin inhibitor 20
CAS:<p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>Fórmula:C19H18O4Forma y color:SolidPeso molecular:310.34BIIB028
CAS:<p>BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.</p>Fórmula:C19H21ClN5O5PForma y color:SolidPeso molecular:465.83Tubulin inhibitor 26
CAS:<p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>Fórmula:C17H19N3O3Forma y color:SolidPeso molecular:313.35O-GlcNAcase-IN-4
CAS:<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Fórmula:C16H22FN5O3SForma y color:SolidPeso molecular:383.44BMS-587101
CAS:<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Fórmula:C26H20Cl2N4O4SForma y color:SolidPeso molecular:555.43Tubulin polymerization-IN-37
CAS:<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Fórmula:C19H20N2O4Forma y color:SolidPeso molecular:340.37BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Fórmula:C25H29N3NaO7SForma y color:SolidPeso molecular:538.57THK-5117
CAS:<p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>Fórmula:C19H19FN2O2Forma y color:SolidPeso molecular:326.36Integrin modulator 1
CAS:<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Fórmula:C13H14N2O4Pureza:99.61%Forma y color:SolidPeso molecular:262.26XVA143
CAS:<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Fórmula:C25H21Cl2N3O8Forma y color:SolidPeso molecular:562.36Debio 0617B
CAS:<p>Debio 0617B inhibits kinases for AML stem cell treatment, targeting JAK, ABL, SRC, and STAT3-related tumours.</p>Fórmula:C28H23ClF3N7O2Forma y color:SolidPeso molecular:581.98Antitumor agent-68
CAS:<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Fórmula:C17H11NO2Forma y color:SolidPeso molecular:261.27Antitumor agent-71
CAS:<p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>Fórmula:C26H31N5O4SForma y color:SolidPeso molecular:509.62BMS-358233
CAS:<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Fórmula:C25H25ClN6O2SForma y color:SolidPeso molecular:509.02PU24FCl
CAS:<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Fórmula:C20H21ClFN5O3Forma y color:SolidPeso molecular:433.86KIF18A-IN-4
CAS:<p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>Fórmula:C22H27N3O3SForma y color:SolidPeso molecular:413.53Sabeluzole
CAS:<p>Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.</p>Fórmula:C22H26FN3O2SPureza:98.51%Forma y color:SolidPeso molecular:415.52Valategrast hydrochloride
CAS:<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Fórmula:C30H33Cl4N3O4Pureza:98%Forma y color:SolidPeso molecular:641.41αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Fórmula:C28H35F3N6O8SPureza:98%Forma y color:SolidPeso molecular:672.67K-80003
CAS:<p>K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.</p>Fórmula:C22H21FO2Pureza:99.76%Forma y color:SolidPeso molecular:336.4PS315
CAS:<p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>Fórmula:C23H19ClO2Pureza:98%Forma y color:SolidPeso molecular:362.85AKT-IN-2
CAS:<p>AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).</p>Fórmula:C25H34F3N7OPureza:98%Forma y color:SolidPeso molecular:505.58Balamapimod
CAS:<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Fórmula:C30H32ClN7OSPureza:98%Forma y color:SolidPeso molecular:574.14GB1874
CAS:<p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>Fórmula:C24H27N3O2SForma y color:SolidPeso molecular:421.56AMP-PCP
CAS:<p>AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.</p>Fórmula:C11H18N5O12P3Pureza:98%Forma y color:SolidPeso molecular:505.21SR31527
CAS:<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Fórmula:C15H14ClN3OSPureza:98%Forma y color:SolidPeso molecular:319.81Eg5 Inhibitor V, trans-24
CAS:<p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>Fórmula:C26H21N3O3Pureza:99.75%Forma y color:SolidPeso molecular:423.46BBO-10203
CAS:<p>BBO-10203 is an oral small molecule that disrupts PI3Kα-Ras interaction, inhibits Akt signaling selectively, and targets KRAS-mutant tumors.</p>Fórmula:C34H30F2N6O3SPureza:98.62%Forma y color:SolidPeso molecular:640.7ZINC194100678
CAS:<p>ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.</p>Fórmula:C10H13N5OPureza:98.3%Forma y color:SolidPeso molecular:219.24TC-Mps1-12
CAS:<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Fórmula:C17H20N6OPureza:98%Forma y color:SolidPeso molecular:324.38KP-23172
CAS:<p>KP-23172 is a inhibitor of PI3-K/Akt pathway.</p>Fórmula:C10H4N6OPureza:98%Forma y color:SolidPeso molecular:224.18Tau-aggregation and neuroinflammation-IN-1
CAS:<p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>Fórmula:C25H20N2O7Pureza:99.85%Forma y color:SolidPeso molecular:460.44BCR-ABL-IN-7
CAS:<p>BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.</p>Fórmula:C19H16FN3O3SPureza:98.28%Forma y color:SolidPeso molecular:385.41CpCDPK1/TgCDPK1-IN-1
CAS:<p>CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.</p>Fórmula:C18H17N5Pureza:99.61%Forma y color:SolidPeso molecular:303.36AM-5308
CAS:<p>AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.</p>Fórmula:C26H35N5O5SPureza:98.06% - 99.58%Forma y color:SolidPeso molecular:529.65CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Fórmula:C18H18ClN5OPureza:98.81%Forma y color:SolidPeso molecular:355.82Pentachloropseudilin
CAS:<p>Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.</p>Fórmula:C10H4Cl5NOPureza:98.14%Forma y color:SolidPeso molecular:331.41Tyrphostin AG 568
CAS:<p>Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.</p>Fórmula:C13H9N5O2Pureza:98%Forma y color:SolidPeso molecular:267.24DHNQ
CAS:<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Fórmula:C18H14N2OForma y color:SolidPeso molecular:274.32NSC305787
CAS:<p>NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.</p>Fórmula:C25H30Cl2N2OPureza:99.40%Forma y color:SolidPeso molecular:445.42Clathrin-IN-25
CAS:<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Fórmula:C19H13KNO5SForma y color:SolidPeso molecular:406.47
